Abstracts Archive - Page 1364 of 2425 - ACR Meeting Abstracts

Abstract Number: 2377 • 2017 ACR/ARHP Annual Meeting
Impact of Body Mass Index and Weight Loss on Incident Disability in Patients with Rheumatoid Arthritis
Joshua Baker¹, Ted R. Mikuls², Bryant R. England³, Michael D. George⁴, Grant Cannon⁵, Harlan Sayles⁶, Brian Sauer⁵, Liron Caplan⁷ and Kaleb Michaud⁶, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁴Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶University of Nebraska Medical Center, Omaha, NE, ⁷Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Obese patients with rheumatoid arthritis (RA) have greater disability in cross-sectional studies. There are no long-term studies that assess trajectories of disability among individuals…
Abstract Number: 2378 • 2017 ACR/ARHP Annual Meeting
Body Mass Index and Persistence of Conventional Dmards and TNF Inhibitors in Rheumatoid Arthritis
Caroline McCulley¹, Ted R. Mikuls², Jennifer Barton³, Grant Cannon⁴, Brian C. Sauer, PhD⁵, Liron Caplan⁶, Bryant R. England⁷, Chia-Chen Teng⁸ and Joshua Baker⁹, ¹Rheumatology, Oregon Health & Science University, Portland, OR, ²Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³VA Portland Health Care System, Portland, OR, ⁴Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁵Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁶Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁷Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁸Rheumatology, University of Utah, Salt Lake City, UT, ⁹Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Low body mass index (BMI) is associated with more destructive disease in rheumatoid arthritis (RA). Paradoxically, obese patients have been shown in studies to…
Abstract Number: 2379 • 2017 ACR/ARHP Annual Meeting
Effect of DKK-1 and Osteoprotegerin on Bone Mass in Tightly Controlled Rheumatoid Arthritis
Javier Narváez¹, Irene Martin-Esteve², Andrea Zacarias³, Pedro Alia⁴, Estibaliz Loza⁵, Loreto Carmona⁵, Joan Miquel Nolla² and Carmen Gomez Vaquero⁶, ¹Rheumatology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, ²Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Hospital Universitari de Bellvitge, Barcelona, Spain, ⁴Clinical Laboratory Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, ⁵Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, ⁶Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: To analyze the association between osteoprotegerin (OPG) and Dickkopf-related protein 1 (DKK-1) and the annual percent change (Δ%) in bone mineral density (BMD) in patients…
Abstract Number: 2380 • 2017 ACR/ARHP Annual Meeting
The Use of Fibroscan in Detecting Early Liver Fibrosis in RA Patients on Long Term MTX with Normal Liver Enzymes
Malack Alachkar¹, T Mathialahan², Sandra Walsh² and Vun Lim³, ¹Rheumatology, The Pennine Acute Hospitals NHS Trust, Manchester, United Kingdom, ²Gastroenterology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham, United Kingdom, ³Rheumatology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham, United Kingdom
Background/Purpose: FibroScan (FS) is a non-invasive investigation that allows assessment of possible liver fibrosis by measuring liver stiffness. There are studies which confirm that MTX-related…
Abstract Number: 2381 • 2017 ACR/ARHP Annual Meeting
Hematologic Abnormalities during the Use of Low Dose Methotrexate for Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Kathleen Vanni¹, Zhi Zhang¹, Cassandra Corrigan² and Daniel H. Solomon³, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology, Brigham and Women's Hospital, Boston, MA, ³Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Methotrexate (MTX) is known to increase the risk of cytopenias, but the prevalence of hematologic abnormalities among patients taking low dose MTX is poorly…
Abstract Number: 2382 • 2017 ACR/ARHP Annual Meeting
Reliability of the Biochemical Bone Markers CTX and P1NP during a TNF-Inhibitor Treatment Cycle in Patients with Rheumatoid Arthritis
Kim Holmsted¹, Niklas Rye Jørgensen² and Ole Rintek Madsen¹, ¹Center for Rheumatology and Spine Diseases & The DANBIO Registry, Copenhagen University Hospital Rigshospitalet Gentofte Glostrup, Copenhagen, Denmark, ²Dept. of Clinical Biochemistry, Rigshospitalet, Glostrup, Denmark
Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of developing osteoporosis. Dual Energy X-ray Absorptiometry (DXA) with assessment of BMD is used for…
Abstract Number: 2383 • 2017 ACR/ARHP Annual Meeting
Frailty and Risk of Fractures in Patients with Rheumatoid Arthritis: Data from the Ontario Best Practices Research Initiative (OBRI)
Guowei Li¹, Xiuying Li², Angela Cesta³, Arthur Lau⁴, Claire Bombardier³ and J Adachi⁵, ¹Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada, ²University of Toronto, TORONTO, ON, Canada, ³Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ⁴50 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ⁵St Joseph's Healthcare Hamilton, Hamilton, ON, Canada
Background/Purpose: Measuring the degree of frailty can help screen, quantify and predict future risk of adverse health outcomes at a clinical research level and at…
Abstract Number: 2384 • 2017 ACR/ARHP Annual Meeting
Incidence and Predictors of Dyspnea on Exertion in a Prospective Cohort of Patients with Rheumatoid Arthritis
Jeffrey A. Sparks¹, Tracy Doyle², Beatrice Pan³, Christine Iannaccone⁴, Michelle Frits³, Paul Dellaripa⁵, Ivan Rosas⁵, Bing Lu⁶, Michael Weinblatt⁶, Nancy A. Shadick⁷ and Elizabeth Karlson⁵, ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Pulmonary Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Dyspnea on exertion symptoms often prompt clinical evaluation related to respiratory, cardiovascular, and functional status. However, the incidence and predictors of clinically significant…
Abstract Number: 2385 • 2017 ACR/ARHP Annual Meeting
High Incidence of Hepatitis Related to HBV Reactivation in Rheumatoid Arthritis Patients with Resolved Hepatitis B Infection during Rituximab Treatment
Ming-Han Chen¹, Yen-Po Tsao², Yi-Hsiang Huang³, Chung-Tei Chou⁴ and Chang Youh Tsai², ¹Division of Allergy- Immunology- Rheumatology, Department of Medicine, Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ²Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ³Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
AbstractBackground/Purpose: Rituximab-based chemotherapy can induce hepatitis B virus (HBV) reactivation (HBVr) in patients with hematological malignancies who have been exposed to HBV infection. However, informative…
Abstract Number: 2386 • 2017 ACR/ARHP Annual Meeting
The Risk Factors of Newly Developing/Worsening Pulmonary Abnormalities in Rheumatoid Arthritis
Ayae Tanaka¹, Kazuhiro Kurasawa¹, Yuta Takamura¹, Tomoyuki Miyao¹, Ryutaro Yamazaki², Satoko Arai¹, Takayoshi Owada¹, Reika Maezawa¹ and Masafumi Arima¹, ¹Rheumatology, Dokkyo Medical University, Mibu, Tochigi, Japan, ²Rheumatology, Dokkyo Medical University, Mibu, tochigi, Japan
Background/Purpose: Rheumatoid arthritis (RA) is a systemic inflammatory disease that affects various organs including the lung. The pulmonary involvement is critical for prognosis of the…
Abstract Number: 2387 • 2017 ACR/ARHP Annual Meeting
Prevalence of Hepatitis C Virus Infection in Egyptian Patients with Rheumatoid Arthritis
Dahlia Abdel Mohsen¹, Sherin H. Hamza¹, Nashwa Aly Morshedy¹, F. DeWolfe Miller² and Mahmoud S. Elzalabany^3,4, ¹Internal Medicine and Rheumatology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt, ²Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, ³Internal Medicine Department, Ahmed Maher Teaching Hospital, Cairo, Egypt, ⁴Tahya Misr HCV Treatment Center, Luxor, Egypt
Background/Purpose: HCV is a major public health problem affecting approximately 2-3% of the world’s population with about 130-150 million people chronically infected worldwide. Egypt has…
Abstract Number: 2388 • 2017 ACR/ARHP Annual Meeting
Women and Men with Rheumatoid Arthritis Present with Different Risks for Glucocorticoid-Related Comorbidities
Dörte Huscher¹, Katinka Albrecht¹, Frank Buttgereit², Thorsten Eidner³, Stefan Kleinert⁴, Wolfgang Ochs⁵ and Angela Zink⁶, ¹Epidemiology Unit, German Rheumatism Research Centre (DRFZ), Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité Univeris, Berlin, Germany, ³Rheumatology/ Osteology, Friedrich-Schiller-University Jena, University Clinic, Jena, Germany, ⁴Rheumatologie, Praxisgemeinschaft Rheumatologie-Nephrologie, Rheumatologische Schwerpunktpraxis, Erlangen, Germany, ⁵Internistisch-rheumatologische Praxisgemeinschaft Bayreuth, Bayreuth, Germany, ⁶Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany
Background/Purpose: Osteoporosis, diabetes, hypertension and cardiovascular diseases are the most threatening glucocorticoid (GC)-related comorbidities in rheumatoid arthritis (RA), both from the patients and rheumatologists perspective1.…
Abstract Number: 2389 • 2017 ACR/ARHP Annual Meeting
Joint Surgery in Rheumatoid Arthritis 1980-2013: A Population-Based Study to Identify Risk Factors and Time Trends in Incidence
Michael Richter¹, Cynthia S. Crowson², Eric L. Matteson³ and Ashima Makol³, ¹Internal Medicine, Mayo Clinic, Rochester, MN, ²Department of Medicine, Division of Rheumatology,Mayo Clinic, Rochester, MN, ³Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN
Background/Purpose: Over the past two decades, the use of disease modifying anti-rheumatic drugs and treat-to-target strategies have dramatically improved the outcomes of patients with rheumatoid…
Abstract Number: 2390 • 2017 ACR/ARHP Annual Meeting
Trends and Predictors of Guideline Adherence for Glucocorticoid-Induced Osteoporosis Prevention in an Early Rheumatoid Arthritis Cohort
Stephanie Gottheil¹, Orit Schieir², Carter Thorne³, Carol A Hitchon⁴, Diane Tin⁵, Edward C. Keystone⁶, Gilles Boire⁷, Boulos Haraoui⁸, Susan J. Bartlett⁹, Vivian P. Bykerk¹⁰ and Janet E. Pope¹¹, ¹University of Western Ontario, LONDON, ON, Canada, ²McGill University, Montreal, ON, Canada, ³University of Toronto, Newmarket, ON, Canada, ⁴University of Manitoba, Winnipeg, MB, Canada, ⁵The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ⁶Mt. Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁸Institute de Rheumatologie, Montreal, QC, Canada, ⁹Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ¹⁰2-005, Mt Sinai Hospital, Toronto, ON, Canada, ¹¹Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada
Background/Purpose: RA patients are at a high risk of osteoporosis and fracture, in part due to frequent glucocorticoid use. Despite recommendations from ACR guidelines on…
Abstract Number: 2391 • 2017 ACR/ARHP Annual Meeting
Incidence of Infections in Early Arthritis
Meriem Kerbachi¹, Louis Bessette², Cristiano S. Moura³, Sasha Bernatsky⁴, Orit Schieir⁵, Susan J. Bartlett⁶, Carol A Hitchon⁷, Janet E. Pope⁸, Gilles Boire⁹, Boulos Haraoui¹⁰, Edward C. Keystone¹¹, Diane Tin¹², Carter Thorne¹³ and Vivian P. Bykerk¹⁴, ¹McGill University, Montreal, QC, Canada, ²Centre d'ostéoporose et de rhumatologie de Québec (CORQ), Québec, QC, Canada, ³1Division of Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ⁴Divisions of Rheumatology and Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁵McGill University, Montreal, ON, Canada, ⁶Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ⁷University of Manitoba, Winnipeg, MB, Canada, ⁸Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada, ⁹Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ¹⁰Institut de Rhumatologie de Montréal, Montreal, QC, Canada, ¹¹Mt. Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³University of Toronto, Newmarket, ON, Canada, ¹⁴2-005, Mt Sinai Hospital, Toronto, ON, Canada
Background/Purpose: Few studies have focused on analyzing infection risk in recent-onset rheumatoid arthritis (RA).The main objective of this study was to estimate the incidence of…

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