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  • Abstract Number: 2412 • 2018 ACR/ARHP Annual Meeting

    Evaluating Gaps in Reproductive Health Knowledge Among Women with Rheumatic Diseases

    Mehret Birru Talabi1, Megan E. B. Clowse2, Susan J. Blalock3, Lan Yu4, Alaina Chodoff5 and Sonya Borrero4, 1Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, 3Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 4Medicine, University of Pittsburgh, Pittsburgh, PA, 5General Internal Medicine, UPMC, Pittsburgh, PA

    Background/Purpose: While women with rheumatic diseases may face considerable reproductive health challenges, few studies have objectively assessed what these women know about their reproductive risks.…
  • Abstract Number: 2413 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Mixed Connective Tissue Disease: Results from a Multicentre Cohort Study

    Massimo Radin1, Karen Schreiber2, Maria Jose Cuadrado3, Irene Cecchi4, Laura Andreoli5, Franco Franceschini6, Maria Teresa Caleiro7, Danieli Andrade8, Elena Gibbone9, Munther A Khamashta10, Jill P. Buyon11, Peter M. Izmirly12, Maria Aguirre13, Chiara Benedetto9, Dario Roccatello14, Luca Marozio15 and Savino Sciascia16, 1Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 2Department of Thrombosis and Haemophilia, Guy's and St Thomas' Hospital, London, United Kingdom., London, United Kingdom, 3Clinica Universidad de Navarra, Madrid, Spain, 4Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 5Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy, Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 6Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy, Rheumatology and Clinical Immunology, Brescia, Italy, 7Rheumatology, University of São Paulo, Tucson, AZ, 8Rheumatology, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 9University of Turin, Turin, Italy, 10Graham Hughes Lupus Research Laboratory, The Rayne Institute, London, United Kingdom, 11Medicine, New York University School of Medicine, New York, NY, 12NYU Langone Health, New York, NY, 13IMIBIC, Cordoba, Cordoba, Spain, 14Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy, 15University of Turin, Torino, Italy, 16Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy

    Background/Purpose: Mixed connective tissue disease (MCTD) is characterized by signs and symptoms of a combination of disorders, primarily systemic lupus erythematosus (SLE), scleroderma and polymyositis…
  • Abstract Number: 2414 • 2018 ACR/ARHP Annual Meeting

    The Global Antiphospholipid Syndrome Score in Women with Systemic Lupus Erythematosus and Adverse Pregnancy Outcomes

    Karen Schreiber1, Massimo Radin2, Irene Cecchi3, Elena Rubini4, Dario Roccatello5, Søren Jacobsen6, Maria Jose Cuadrado7 and Savino Sciascia8, 1Department of Thrombosis and Haemophilia, Guy's and St Thomas' Hospital, London, United Kingdom., London, United Kingdom, 2Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 3Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 4Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bosco Hospital, Turin, Italy., Turin, Italy, 5Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy, 6University of Copenhagen, Copenhagen, Denmark, 7Clinica Universidad de Navarra, Madrid, Spain, 8Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy

    Background/Purpose: Systemic lupus erythematosus (SLE) and antiphospholipid antibodies (aPL) are associated with pregnancy complications. Methods: 143 women ever pregnant with SLE who presented in our…
  • Abstract Number: 2415 • 2018 ACR/ARHP Annual Meeting

    Increased Sperm DNA Fragmentation in Male Systemic LUPUS Erythematosus Patients

    Bruno C Tiseo1, Clovis A Silva2, Eduardo Ferreira Borba3, Gabriela A Munhoz3, Miguel Srougi1, Eloisa Bonfa4 and Marcello Cocuzza1, 1Discipline of Urology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, 2Pediatric Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 3Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 4Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Gonadal dysfunction may affect male systemic lupus erythematosus (SLE) patients. Recently, sperm DNA integrity analysis has shown better diagnostic and prognostic performance for predicting…
  • Abstract Number: 2416 • 2018 ACR/ARHP Annual Meeting

    Good Pregnancy and Neonatal Outcomes in Lupus Nephritis Patients with Complete Remission

    Weixin HU, Kang LI, Yinghua CHEN, Zhenzhao LIU, Liu YANG, Duqun CHEN and Haitao Zhang, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China

    Background/Purpose: To investigate the outcomes of pregnancy and neonatal and the risk factors of lupus flares and pregnancy complications in Chinese patients with lupus nephritis…
  • Abstract Number: 2417 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Systemic Lupus Erythematous and Pre-Systemic Lupus Erythematous: A Population-Based Cohort Study

    A. Nicole Wade1, Mary A. De Vera2, Eric C. Sayre3 and J. Antonio Avina-Zubieta4, 1Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 3Arthritis Research Canada, Richmond, BC, Canada, 4Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: The adverse effects of systemic lupus erythematosus (SLE) on maternal and fetal outcomes in pregnancy have been explored mainly in clinic-based cohorts. However, data…
  • Abstract Number: 2418 • 2018 ACR/ARHP Annual Meeting

    Awareness of Fertility and Contraception Issues Among Women with Rheumatologic Diseases

    Christina Payne1, Meagan Clark2, Sneha Patel3, Tanya Allawh3, Mei-An Ty-Arias2, Ashley Davis2 and Arundathi ‎ Jayatilleke ‎4, 1Rheumatology, Drexel University COM/ HUH, Philadelphia, PA, 2Drexel University COM, Philadelphia, PA, 3Internal Medicine, Drexel University COM, Philadelphia, PA, 4Rheumatology, Drexel University COM, Philadelphia, PA

    Background/Purpose: Because many autoimmune conditions preferentially affect women of childbearing age and both disease and treatment can negatively affect pregnancy outcomes, healthcare providers to women…
  • Abstract Number: 2419 • 2018 ACR/ARHP Annual Meeting

    Needs Assessment and Implementation of a Reproductive Health Intention Screen for Women with Systemic Rheumatic Diseases

    Elizabeth Janiak1, Latoya Bartlett2, Joy Gulla2, Bill Albert3, Sonali Desai4, Susan Ritter5, Laura Tarter5, Jonathan Coblyn5, Bonnie L. Bermas6, Wan-Ju Wu1, Caryn Dutton1, Lydia Pace7 and Candace H. Feldman4, 1Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Power to Decide, Washington, DC, DC, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 6Rheumatology, University of Texas, Southwestern, Dallas, TX, 7Division of Women's Health, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Among women with systemic rheumatic diseases (SRD), poor maternal and fetal outcomes may occur if disease activity and medication use are not optimized preconception.…
  • Abstract Number: 2420 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcome and Perinatal Complications of Neonate Born to Mothers with Juvenile Idiopathic Arthritis in Asia

    Chao-Yi Wu1, Shang-Chun Changchien2, Huang-Yu Yang3, Kuo-Wei Yeh4 and Jing-Long Huang1,2, 1Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 2Medicine, Chang-Gung University, Taoyuan city, Taiwan, 3Department of Nephrology,, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 4Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the leading pediatric rheumatic disease affecting 30 out of a million women. Although spontaneous remission may occur in most…
  • Abstract Number: 2421 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Women with Rheumatic Diseases and Thrombophilia Treated in a Multidisciplinary Unit

    Isabel Añón Oñate1, Irene Notario1, Miguel Ángel Ferrer1, Lorena Pérez1, María Ramírez1 and Rafael Cáliz2, 1Rheumatology, Hospital Universitario Virgen de las Nieves, Granada, Spain, 2Hospital Universitario Virgen de las Nieves, Granada, Spain

    Background/Purpose: To evaluate the efficacy of the treatment on the pregnancy outcomes of women with Rheumatic Diseases and Thrombophilia from a Spanish cohort. Their pregnancies…
  • Abstract Number: 2422 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Patients with Interstitial Lung Disease Related to Autoimmune Disease and Sarcoidosis

    Stephanie L. Giattino, Amanda M. Eudy and Megan E. B. Clowse, Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC

    Background/Purpose: Currently published data regarding pregnancy outcomes in patients with interstitial lung disease (ILD) related to autoimmune disease and sarcoidosis is limited, with widely variant…
  • Abstract Number: 2423 • 2018 ACR/ARHP Annual Meeting

    Births to Women with Systemic Lupus Erythematosus Can be Identified Accurately in the Electronic Health Record

    Ashley Blaske1, Amanda M. Eudy2, Jim C. Oates3, Megan E. B. Clowse2 and April Barnado4, 1Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 2Division of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC, 3Division of Rheumatology & Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, 4Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN

     Background/Purpose: Studying births in women with systemic lupus erythematosus (SLE) is difficult given its rarity and the challenges of randomized trials. While the electronic health…
  • Abstract Number: 2424 • 2018 ACR/ARHP Annual Meeting

    Bisphosphonates during Pregnancy: A Systematic Review Sayanika Kaur MD Fellow Drexel Rheumatology, Mojdeh Khaamesi MD Resident Internal Medicine Arundathi Jayatilleke MD Program Director Drexel Rheumatology

    Sayanika Kaur1, Mojdeh Khaamesi2 and Arundathi ‎ Jayatilleke ‎1, 1Rheumatology, Drexel University COM, Philadelphia, PA, 2Internal Medicine, Drexel University COM, Philadelphia, PA

    Background/Purpose: Recent ACR guidelines on prevention and treatment of CS-induced osteoporosis state that women of childbearing potential who are at moderate-to-high risk of fracture should…
  • Abstract Number: 2425 • 2018 ACR/ARHP Annual Meeting

    The Impact of Biologic Treatment for Rheumatoid Arthritis Patients Who Hope to Conceive

    Hiromi Shimada, Taichi Miyagi, Mikiya Kato, Risa Wakiya, Shusaku Nakashima, Tomohiro Kameda and Hiroaki Dobashi, Internal Medicine Division of Hematology, Rheumatology, and Respiratory Medicine, Kagawa University, Kagawa, Japan

    Background/Purpose: Previous reports revealed that it was difficult for rheumatoid arthritis (RA) patients to conceive1). Age, nulliparity, disease activity, NSAIDs, corticosteroid was known as the…
  • Abstract Number: 2426 • 2018 ACR/ARHP Annual Meeting

    Defining a Standardized Core Data Set for Pregnancy Registers in Rheumatic Diseases – an European Approach

    Yvette Meißner1, Anja Strangfeld1, Nathalie Costedoat-Chalumeau2,3, Frauke Förger4,5, Anna Moltó6, Marianne Wallenius7,8 and Rebecca Fischer-Betz9, 1Programme Area Epidemiology, German Rheumatism Research Center, Berlin, Germany, 2Université Paris-Descartes, Paris, France, 3Internal Medicine, Hopital Cochin, Paris, France, 4University of Bern, Bern, Switzerland, 5Rheumatology, Clinical Immunology and Allergology, Inselspital-University Hospital, Bern, Switzerland, 6Rheumatology B Department, Paris Descartes University, Cochin Hospital, AP-HP,Paris, Paris, France, 7Norwegian University of Science and Technology, Trondheim, Norway, 8St. Olav's University Hospital, Trondheim, Norway, 9Department of Rheumatology and Hiller Research Unit, University Hospital Duesseldorf, Duesseldorf, Germany

    Background/Purpose: Robust data on the outcomes of pregnancy and influence of drug exposure in various inflammatory rheumatic diseases (IRD) are needed. Joint analyses of data…
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