Abstracts Archive - Page 1333 of 2607 - ACR Meeting Abstracts

Abstract Number: 2201 • 2018 ACR/ARHP Annual Meeting
Evaluation of 18f-Fluorodeoxyglucose Positron Emission Tomography/ Magnetic Resonance Imaging (18F-FDG PET/MRI) in C Protein-Induced Myositis Model in Mice
Jeong Yeon Kim^1,2, Jung Woo Byun³, Jae Hwan Shin³, Ji Soo Park^1,2, Ji Hye Lee², Shin Eui Kang^1,4, Hyun Jung Yoo^1,2, Eun Bong Lee², Do Won Hwang³, Yun Sang Lee³, Jin Chul Paeng³, Eun Young Lee⁵ and Yeong Wook Song^1,6, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ³Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, seoul, Korea, Republic of (South), ⁵Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), ⁶Rheumatology, Seoul National University Hospital, Seoul, Korea, Republic of (South)
Background/Purpose: Polymyositis is a chronic inflammatory myopathy with proximal muscle weakness due to lymphocyte infiltration, especially CD8 + T cells to the muscle layer. C…
Abstract Number: 2202 • 2018 ACR/ARHP Annual Meeting
The Relationship between Periodontitis and the Treatment Response to Biologics in Rheumatoid Arthritis Patients; A Post-Hoc Analysis Using [18F] Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
Masahiro Tachibana^1,2, Yukio Yonemoto³, Takahito SUTO³, Koichi OKAMURA³, Chisa OKURA³, Hideo SAKANE³ and Hirotaka CHIKUDA³, ¹Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan, ²Orthopedic Surgery, Kiryu Kosei General Hospital, Kiryu, Japan, ³Orthopaedic Surgery, Gunma University Graduate School of Medicine, MAEBASHI, Japan
Background/Purpose: Rheumatoid arthritis(RA) and periodontitis have been suggested to be related, and they share many clinical and pathologic features. Both diseases are chronic inflammatory diseases…
Abstract Number: 2203 • 2018 ACR/ARHP Annual Meeting
Atherosclerotic Inflammation in Rheumatoid Arthritis Patients: A Post-Hoc Study Using Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
Yukio Yonemoto¹, Masahiro Tachibana², Koichi OKAMURA¹, Takahito SUTO¹, Hideo SAKANE¹, Chisa OKURA¹, Tetsuya Kaneko² and Hirotaka CHIKUDA¹, ¹Orthopaedic Surgery, Gunma University Graduate School of Medicine, MAEBASHI, Japan, ²Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan
Background/Purpose: Rheumatoid arthritis (RA) has long been associated with an increased cardiovascular risk, and despite substantial improvements in disease management, its associated mortality remains high.…
Abstract Number: 2204 • 2018 ACR/ARHP Annual Meeting
Clinical Utility of a Multi-Energy Spectral CT in Crystal Arthritis
Lisa K. Stamp¹, Nigel Anderson², Fabio Becce³, Maya Rajeswari², Matthew Polson⁴, Olivier Guyen³, Anais Viry³, Chloe Choi², Tracy Kirkbride⁵ and Aamir Raja², ¹University of Otago, Christchurch, New Zealand, ²University of Otago, Christchurch, Christchurch, New Zealand, ³Lausanne University Hospital, Lausanne, Switzerland, ⁴University of Canterbury, Christchurch, New Zealand, ⁵Ara Institute of Canterbury, Christchurch, New Zealand
Background/Purpose: The gold standard for the diagnosis of crystal-related arthritis requires aspiration and visualization of crystals from synovial fluid or tophus material. However, crystal identification…
Abstract Number: 2205 • 2018 ACR/ARHP Annual Meeting
Initial Phase 2 Clinical Data of SEL-212 in Symptomatic Gout Patients: Measurement of Dissolution of Urate Deposits Associated with Monthly Dosing of a Pegylated Uricase (Pegadricase) with Svp-Rapamycin By Dual Energy Computed Tomography
Rehan Azeem¹, Earl Sands¹, Lloyd Johnston², Wesley DeHaan Ph.D.², Alan J. Kivitz³, Takashi Kei Kishimoto², Justin Park¹ and Savvas Nicolaou⁴, ¹Selecta Biosciences, Inc, Watertown, MA, ²Selecta Biosciences, Watertown, MA, ³Altoona Center for Clinical Research, Duncansville, PA, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Pegylated uricases are therapies for treatment of severe chronic gout, particularly for rapid resolution of tophi. However, uricases are limited by induction of anti-drug…
Abstract Number: 2206 • 2018 ACR/ARHP Annual Meeting
Joint Repair While Initiating Biologic Therapy in Rheumatoid Arthritis
Scott Brunet^1,2,3, Sarah Manske^1,2,3, Klaus Engelke^4,5, Steven K. Boyd^1,2,3 and Cheryl Barnabe^2,6, ¹Biomedical Engineering, University of Calgary, Calgary, AB, Canada, ²McCaig Institute for Bone and Joint Health, Calgary, AB, Canada, ³Department of Radiology, University of Calgary, Calgary, AB, Canada, ⁴Institute of Medical Physics, University of Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Department of Medicine, Erlangen University Hospital, Erlangen, Germany, ⁶Division of Rheumatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Functional decline and reduced quality of life for patients with rheumatoid arthritis (RA) results from chronic changes to joints in patients, including bone erosions…
Abstract Number: 2207 • 2018 ACR/ARHP Annual Meeting
Detecting Hand Joint Ankylosis in Radiographic Images Using Deep Learning: A Step in Development of Automatic Radiographic Scoring System for Bone Destruction
Keisuke Izumi^1,2, Masahiro Hashimoto³, Kanata Suzuki⁴, Toshio Endoh⁴, Kentaro Doi⁵, Yuki Iwai⁵, Masahiro Jinzaki³, Shigeru Ko⁶ and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ³Department of Radiology, Keio University School of Medicine, Tokyo, Japan, ⁴Machine Learning Technology Project, Artificial Intelligence Laboratory, FUJITSU LABORATORIES LTD., Kawasaki, Japan, ⁵SOLUTIONS DEVELOPMENT DEPT.I, MEDICAL SOLUTIONS DIV.V, Healthcare Solutions Unit. II, FUJITSU LTD., Tokyo, Japan, ⁶Department of Systems Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Artificial intelligence (AI) techniques including deep learning have been rapidly evolving and shown good performance in many fields over recent years. However, there are…
Abstract Number: 2208 • 2018 ACR/ARHP Annual Meeting
Novel Fluorescence Optical Imaging Scoring System of Inflammation in the Hand and Wrist Is in Patients with Rheumatoid Arthritis – Agreement with Ultrasonography and Sensitivity to Change
Mads Ammitzbøll-Danielsen¹, Daniel Glinatsi¹, Lene Terslev² and Mikkel Østergaard^3,4, ¹Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Fluorescence optical imaging (FOI) has been used for assessment of inflammation in the hands and has in several cross sectional studies been compared with…
Abstract Number: 2209 • 2018 ACR/ARHP Annual Meeting
Fluorescence Optical Imaging Xiralite® Is Helpful in the Decision for Rituximab Re-Therapy in Patients with Rheumatoid Arthritis
Sarah Ohrndorf¹, Lisa Ridha², Anne-Marie Glimm³, Gerd R. Burmester¹, Gabriela Schmittat³, Marina Backhaus⁴ and Jens Klotsche⁵, ¹Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, ⁴Department of Rheumatology & Immunology, University Medicine Charit, Berlin, Germany, ⁵Program Area Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: Rituximab (RTX) is an effective and well-tolerated therapeutic option in rheumatoid arthritis (RA) patients with insufficient response to TNFα inhibitors. However, the exact time…
Abstract Number: 2210 • 2018 ACR/ARHP Annual Meeting
Effects of Anti-Citrullinated Peptide Antibody (ACPA) on Bone Microstructure in Rheumatoid Arthritis: A HR-pQCT Study
Ikuko Tanaka¹, Takashi Kato², Motokazu Kai³, Kunikazu Ogawa³, Hiroaki Mizuno¹, Mari Ushikubo⁴, Keisuke Izumi⁵, Hisaji Oshima⁶ and Shigenori Tamaki¹, ¹Nagoya Rheumatology Clinic, Nagoya, Japan, ²Department of Radiology, National Center for Geratrics and Gerontology, Obu, Japan, ³Mie Rheumatology Clinic, Suzuka, Japan, ⁴National Tokyo Medical Center, Tokyo, Japan, ⁵Department of connective Tissue Disease, National Tokyo Medical Center, Tokyo, Japan, ⁶Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) induces systemic osteoporosis as well as osteoporotic change in the bones having arthritis by RA. Recently immune complex and anti-citrullinated peptide…
Abstract Number: 2211 • 2018 ACR/ARHP Annual Meeting
Technetium Tc 99m Tilmanocept: A Targeted Immunodiagnostic Radiopharmaceutical for the Assessment of Synovial Macrophage Activity in Rheumatoid Arthritis
Arash Kardan¹, Allison Kissling², Bonnie Abbruzzese², Ahmad Ismail², Rachael Hershey², Carley Hartings², David Ralph², Izabela Gierach², Michael Blue², Hannah Bailey², Christopher Gablemann², Katherine Repp² and Frederick Cope², ¹Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, OH, ²Navidea Biopharmaceuticals, Inc., Dublin, OH
Background/Purpose: Activated macrophages are a critical component of the inflammatory etiology of RA. It is well established that these macrophages perpetuate joint inflammation and destruction…
Abstract Number: 2212 • 2018 ACR/ARHP Annual Meeting
Feasibility and Performance of HR-pQCT-Derived Joint Space Width Measurement As Outcome Parameter in Arthropathic Disease – Lessons from Hemochromatosis Arthropathy
Ursula Heilmeier¹, Andrew J Burghardt¹, Puneet Kapoor², Georg Schett³, Reinhard Voll⁴ and Stephanie Finzel⁵, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany, ⁴Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ⁵Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Background/Purpose: High resolution peripheral quantitative computed tomography (HR-pQCT) allows in vivo 3 D imaging of human joint microstructure and joint space width (JSW) at an…
Abstract Number: 2213 • 2018 ACR/ARHP Annual Meeting
Usefulness of Shoulder Radiographs to Aid in Determining Need for Advanced Imaging to Detect Operable or Inoperable Full-Thickness Rotator Cuff Tears
Ryan Hoggan¹, Andrea Barker², Zhenhao Liu³, Curry L. Koening⁴ and Michael J. Battistone⁵, ¹University of Utah, Salt Lake City, UT, ²Veterans Affairs Salt Lake City Health Care System and University of Utah School of Medicine, Salt Lake City, UT, ³Rheumatology, University of Utah, Salt Lake City, UT, ⁴Division of rheumatology, George E. Wahlen Department of Veterans Affairs Medical Center Salt Lake City and University of Utah, University of Utah School of Medicine, Salt Lake City, UT, ⁵Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT
Background/Purpose: Full-thickness rotator cuff tears (FTT) can be a debilitating cause of shoulder pain and loss of function. Delay in surgical evaluation may result in…
Abstract Number: 2214 • 2018 ACR/ARHP Annual Meeting
Lung Involvement in Primary Sjögren’s Syndrome: Spectrum of Pulmonary Abnormalities and Computed Tomography Findings
Janet Flores¹, Diego Baenas², Nadia Riscanevo³, Emanuel Saad⁴, Maria Jezabel Haye Salinas⁵, Soledad Retamozo⁶, Ana C. Alvarez⁵, Alejandro Alvarellos⁷, Juan Pablo Pirola⁸, Nadia Benzaquén⁵, Verónica Saurit⁹ and Francisco Caeiro⁸, ¹Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, ²Reumatologia, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, ³Rheumatology, Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, ⁴Internal medicine, Hospital Privado, Cordoba, Argentina, ⁵Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, ⁶Sociedad Argentina de Reumatologia, Córdoba, Argentina, ⁷Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ⁸Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, ⁹Hospital Privado Centro Médico de Córdoba, Cordoba, Argentina
Background/Purpose: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that affects exocrine glands. It can generate pulmonary compromise due to dysfunction of the glandular…
Abstract Number: 2215 • 2018 ACR/ARHP Annual Meeting
Evaluation of Left Ventricular Systolic and Diastolic Myocardial Function in Patients with Ankylosing Spondylitis By Speckle-Tracking Echocardiography
Hang Yang¹, Yi Zhao¹, Yujia Liang², Wenkai Yan³, Yi Liu⁴, Lingshu Zhang¹ and Tony Marion⁵, ¹Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China, ²Department of Cardiology, West China Hospital, Sichuan University, CHENGDU, China, ³Southern Medical University, GUANGZHOU, China, ⁴Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, Chengdu, China, ⁵Immunology and Biochemistry University of Tennessee Health Science Center, Memphis, TN
Background/Purpose: Patients with ankylosing spondylitis (AS) are at increased risk for cardiovascular disease (CVD), although strategies to detect subclinical CVD are poorly characterized. The aim…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].