Abstracts Archive - Page 1316 of 2607 - ACR Meeting Abstracts

Abstract Number: 1945 • 2018 ACR/ARHP Annual Meeting
Early Prediction of Long-Term Renal Outcomes in Lupus Nephritis Using Hazard Index Equations
Farah Tamirou¹, Meggan Mackay², Maria Dall'Era³, Joanna Fishbein⁴, Kenneth C. Kalunian⁵, Brad H. Rovin⁶ and Frédéric A. Houssiau⁷, ¹Rheumatology Department, Cliniques universitaires Saint-Luc, Brussels, Belgium, ²The Feinstein Institute for Medical Research, Manhasset, NY, ³University of California, San Francisco, San Francisco, CA, ⁴The Feinstein Institute for Medical Research, New York, NY, ⁵University of California San Diego, San Diego, CA, ⁶Division of Nephrology, Ohio State University Medical Center, Columbus, OH, ⁷Pôle de pathologies rhumatismales systémiques et inflammatoires, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium
Background/Purpose: Early endpoints predicting long-term outcome in lupus nephritis (LN), which could be used as outcome measures in clinical trials, are still debated. Recently, a…
Abstract Number: 1946 • 2018 ACR/ARHP Annual Meeting
Changing the Conversation about Pain: Development and Testing of an Interprofessional Pain CME Applicable for Rheumatologists and Rheumatology Health Professionals
Kim Jones¹, Catriona Buist², Denise Taray³, Rubin Halperin⁴, Mark Stephens³ and Nora Stern⁴, ¹Schools of Nursing and Medicine, Oregon Health & Science University, Portland, OR, ²Anesthesiology and Pain Management, Oregon Health & Science University, Portland, OR, ³Oregon State Pain Management Commission, Portland, OR, ⁴Providence St Joseph Health and Services, Portland, OR
Background/Purpose: Pain is a near universal symptom of rheumatic diseases. Persistent pain can cause changes in the central and peripheral nervous system transforming pain from…
Abstract Number: 1947 • 2018 ACR/ARHP Annual Meeting
Do Changes in Pain Sensitization and Depressive Symptoms Mediate the Effect of Extreme Weight Loss on Knee Pain Improvement?
S. Reza Jafarzadeh¹, Tuhina Neogi¹, Joshua J. Stefanik², Margaret M. Clancy¹, Jing-Sheng Li³ and David T. Felson¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Department of Physical Therapy, University of Delaware, Newark, DE, ³College of Health and Rehabilitation Sciences: Sargent College, Boston University, Boston, MA
Background/Purpose: We previously showed that the one-year effects of weight loss on knee pain reduction were not mediated by changes in structural features of osteoarthritis…
Abstract Number: 1948 • 2018 ACR/ARHP Annual Meeting
Beliefs and Preferences for Reducing Sedentary Time in Those with Current or Past Knee Symptoms
Christine Pellegrini^1,2, Sara Powell², Chelsea Larsen² and Siobhan Phillips³, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Exercise Science, University of South Carolina, Columbia, SC, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Physical activity is beneficial for those with current or previous knee symptoms, yet few meet federal physical activity guidelines. Reducing sedentary time, which has…
Abstract Number: 1949 • 2018 ACR/ARHP Annual Meeting
Implementation of a Health Diary for Patients with Fibromyalgia
Verónica De Cillis¹, Ayelen Semerano², Adriana Pérez Dávila², Analía Bohr³, Sandra Pelaez⁴ and E. Scheines⁵, ¹Occupational Therapist Service, Hospital de Rehabilitación Manuel Rocca., Buenos Aires, Argentina, ²Hospital de Rehabilitación Manuel Rocca, Buenos Aires, Argentina, ³Rheumatology Section, Hospital de Rehabilitación Manuel Rocca, Buenos Aires, Argentina, ⁴Research Centre of the St.Justine Hospital, Montreal, QC, Canada, ⁵Reumatology, Instituto de Rehabilitación Psicofísica, CABA, Argentina
Background/Purpose: Fibromyalgia (FM) is a syndrome of central sensitization that encompasses many disorders where the central nervous system amplifies sensory input across many organ systems…
Abstract Number: 1950 • 2018 ACR/ARHP Annual Meeting
Self-Reported Depression and Anxiety Among US Adults Aged 18-44 Years with Arthritis, National Health Interview Survey 2014-2016
Dana Guglielmo¹, Jennifer M. Hootman², Louise Murphy², Michael Boring³, Kristina Theis², Charles G. Helmick², Kamil E. Barbour² and Patricia Katz⁴, ¹Oak Ridge Institute for Science and Education, Oak Ridge, TN, ²Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ³Cutting Edge Technology and Solutions, Mesa, AZ, ⁴University of California San Francisco, San Francisco, CA
Background/Purpose: Depression and anxiety are frequent comorbid conditions among adults with arthritis, and are associated with poorer quality of life, reduced adherence and efficacy of…
Abstract Number: 1951 • 2018 ACR/ARHP Annual Meeting
The Effect and Psychosocial Impact of a Longstanding Telephone Peer Counseling Service on Volunteers with Systemic Lupus Erythematosus
Priscilla Toral¹, Melissa T. Flores¹, Roberta Horton¹ and Jillian Rose², ¹Social Work Programs, Hospital for Special Surgery, New York, NY, ²Hospital for Special Surgery, New York, NY
Background/Purpose: Studies have demonstrated the value of peer volunteers providing psychosocial support to people living with rheumatic & other chronic conditions. An evaluation was conducted…
Abstract Number: 1952 • 2018 ACR/ARHP Annual Meeting
Experimental Tendinopathy Treatment with SM04755, a Topical Small Molecule Inhibitor of the Wnt Pathway
Vishal Deshmukh, Timothy Seo and Yusuf Yazici, Samumed, LLC, San Diego, CA
Background/Purpose: Tendinopathy is an inflammatory and degenerative disorder caused by injuries and overuse. The Wnt pathway is upregulated in chronic tendinopathy and involved in inflammation,…
Abstract Number: 1953 • 2018 ACR/ARHP Annual Meeting
Randomized Trial on Exercise at Late-Stage after Total Knee Replacement
Sara R. Piva¹, Michael Schneider¹, Charity Moore-Patterson¹, M. Beatriz Catelani¹, Alexandra Gil¹, Brian Klatt², Anthony DiGioia³, Gustavo J. Almeida¹, Samannaaz S. Khoja⁴, Gwendolin Sowa⁵ and James Irrgang¹, ¹Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, ³University of Pittsburgh Medical Center, Pittsburgh, PA, ⁴Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ⁵Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: Total knee replacement (TKR) improves pain and quality of life; however, the functional limitations that existed for years before surgery tend to persist after…
Abstract Number: 1954 • 2018 ACR/ARHP Annual Meeting
Factors Associated with Overweight or Obesity in Athletes 5 Years after Anterior Cruciate Ligament Injury
Louise Thoma¹, Jessica Johnson², Daniel White³, May Arna Risberg^4,5 and Lynn Snyder-Mackler², ¹Physical Therapy, University of Delaware, Newark, DE, ²Physical Therapy; Biomechanics and Movement Science, University of Delaware, Newark, DE, ³Department of Physical Therapy, University of Delaware, Newark, DE, ⁴Norwegian Research Center for Active Rehabilitation, Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway, ⁵Division of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway
Background/Purpose: Obesity and knee injury, including anterior cruciate ligament (ACL) rupture, are strong risk factors for the development of knee osteoarthritis. Identifying participant and post-injury…
Abstract Number: 1955 • 2018 ACR/ARHP Annual Meeting
Race Is Associated with Discharge Disposition after Total Knee Arthroplasty (TKA), Which Is Associated with 90-Day Readmission Rate
Jasvinder A. Singh¹, Michael Kallan² and Said Ibrahim³, ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Pennsylvania, Philadelphia, PA, ³Cornell University, New York, NY
Background/Purpose: To assess whether race/ethnicity is associated with differences in discharge disposition after elective primary total knee arthroplasty (TKA), and if discharge disposition is associated…
Abstract Number: 1956 • 2018 ACR/ARHP Annual Meeting
Cohort Effects in Back Pain: The Effect of Changes in Life-Style and Co-Occurring Conditions
Elizabeth M. Badley^1,2, Anthony V. Perruccio² and Mayilee Canizares², ¹Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ²Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: The goal of this study was to determine a) if the age-trajectory (life course) of back pain differs by birth cohort and b) whether…
Abstract Number: 1957 • 2018 ACR/ARHP Annual Meeting
Peri-Operative Glycemic Evaluation Prior to Total Joint Replacement in Patients with and without Diabetes
Lindsey A. MacFarlane¹, Yinzhu Jin², Patricia D. Franklin³, Joyce Lii⁴, Jeffrey N. Katz⁵ and Seoyoung C. Kim⁶, ¹Rheumatology, Brigham & Women's Hospital, Boston, MA, ²Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worchester, MA, ⁴Brigham and Women'a Hospital, Boston, MA, ⁵Brigham & Women's Hospital and Harvard Medical School, Boston, MA, ⁶Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Elevated hemoglobin A1c (HbA1c) has been associated with a 9-fold increase in wound complications after total joint replacement (TJR). Data suggest that including HbA1c…
Abstract Number: 1958 • 2018 ACR/ARHP Annual Meeting
Gene Expression Pathways across Multiple Tissues in Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Reveal Core Pathways of Disease Pathology
Marcia Friedman¹, Donseok Choi^1,2,3,4, Steven Planck^1,4, James T. Rosenbaum⁵ and Cailin Sibley¹, ¹Oregon Health & Science University, Portland, OR, ²OHSU-PSU School of Public Health, Portland, OR, ³Graduate School of Dentistry, Kyung Hee Universtiy, Seoul, Korea, Republic of (South), ⁴Casey Eye Institute, Portland, OR, ⁵Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR
Background/Purpose: In recent years, several studies have characterized the gene expression signatures of different tissues affected by ANCA-associated vasculitis (AAV). The purpose of this study…
Abstract Number: 1959 • 2018 ACR/ARHP Annual Meeting
Stability of DNA Methylation Signature in Primary RA Synovial Fibroblasts Compared with Cultured Fibroblast-like Synoviocytes
Rizi Ai¹, Deepa Hammaker², Wei Wang³ and Gary S. Firestein⁴, ¹University of California San Diego, La Jolla, CA, ²Medicine, UC San Diego, La Jolla, CA, ³Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, ⁴Medicine, University of California San Diego, La Jolla, CA
Background/Purpose: Rheumatoid arthritis (RA) is an aggressive immune-mediated joint disease with synovial inflammation and joint destruction. Fibroblast-like synoviocytes (FLS) play a key role in mediating…

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