ACR Meeting Abstracts

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  • Abstract Number: 1627 • 2017 ACR/ARHP Annual Meeting

    Changes in Heart Rate Variability Reflect Changes in Clinical Status and Patient Reported Outcomes in Systemic Lupus Erythematosus: A Longitudinal Analysis

    Aikaterini Thanou1, Stavros Stavrakis2, Justin Reynolds3, Stan Kamp1, Paul Kamp1, Judith A. James4 and Joan T. Merrill5, 1Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Oklahoma Health Sciences Center, Ok, OK, 3University of Oklahoma Health Sciences Center, Oklahoma City, OK, 4Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: We have previously observed associations between systemic lupus erythematosus (SLE) disease activity and heart rate variability (HRV) between 2 time points (1). We aim…
  • Abstract Number: 1628 • 2017 ACR/ARHP Annual Meeting

    Atrial Fibrillation/Flutter Hospitalizations Among Patients with SLE and Diabetes Compared to the General U.S. Medicaid Population

    Sarah Chen1, Medha Barbhaiya2, Michael A. Fischer3, Hongshu Guan4, Candace H. Feldman5, Brendan M. Everett6 and Karen H. Costenbader7, 1Brigham and Women's Hospital, Boston, MA, 2Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Rheumatology, Brigham & Women's Hospital, Boston, MA, 6Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 7Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: SLE patients have increased cardiovascular disease (CVD) risk, including higher risk of stroke, compared to age- and sex-matched diabetes mellitus (DM) patients. Although DM…
  • Abstract Number: 1629 • 2017 ACR/ARHP Annual Meeting

    Disease Activity Is an Independent Predictor of Leukopenia in a Large International SLE Cohort

    Rangi Kandane-Rathnayake1, Vera Golder2, Worawit Louthrenoo3, Sargunan Sockalingam4, Aisha Lateef5, Yuan An6, Leonid Zamora7, Yeong-Jian Wu8, Shue-Fen Luo9, Madelynn Chan10, Fiona Goldblatt11, Chak Sing Lau12, Zhan-Guo Li13, Sandra V. Navarra7, Mandana Nikpour14, Eric F Morand15 and Alberta Y. Hoi2, 1Rheumatology, Monash University, Melbourne, Australia, 2Centre for Inflammatory Diseases, Monash University, Melbourne, Australia, 3Division of Rheumatology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand, 4University of Malaya, Kuala Lumpur, Malaysia, 5Medicine, Division of Rheumatology, National University Hospital of Singapore, Singapore, Singapore, 6Peking University People's Hospital, Beijing, China, 7Rheumatology, University of Santo Tomas Hospital, Manila, Philippines, 8Chang Gung University, Taoyuan County, Taiwan, 9Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 10Tan Tock Seng Hospital, Singapore, Singapore, 11Flinders University, Adelaide, Australia, 12Univ Dept of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong, 13Peking University International Hospital, Beijing, China, 14Melbourne University, Melbourne, Australia, 15Monash University, Melbourne, Australia

    Background/Purpose: Leukopenia is commonly seen in SLE, but its predictors are not well understood, as it can be a result of disease activity or bone…
  • Abstract Number: 1630 • 2017 ACR/ARHP Annual Meeting

    Achievement of Lupus Low Disease Activity State (LLDAS) in the Early Phase of Systemic Lupus Erythematosus Prevent Damage Accrual

    Matteo Piga, Alberto Floris, Giulia Cappellazzo, Alessandro Mathieu and Alberto Cauli, Unit and Chair of Rheumatology, University Hospital of Cagliari, Cagliari, Italy

    Background/Purpose: The Asia-Pacific Collaboration Group has recently proposed the definition of Lupus Low Disease Activity state (LLDAS). This potential target in SLE treatment has been…
  • Abstract Number: 1631 • 2017 ACR/ARHP Annual Meeting

    Hospital Readmissions for SLE in the United States: A National Database Study

    Narender Annapureddy1, Aparna Saha2 and Girish Nadkarni3, 1Vanderbilt University Medical Center, Nashville, TN, 2Department of Public Health, Icahn School of Medicine at Mount Sinai, New york, NY, 3Division of Nephrology, Icahn School of Medicine at Mount Sinai, New york, NY

    Hospital Readmissions For SLE In The United States: A National Database Study Background/Purpose: Systemic lupus erythematosus (SLE) is associated with significant mortality and morbidity, and…
  • Abstract Number: 1632 • 2017 ACR/ARHP Annual Meeting

    SLE Characteristics Associated with Modified Framingham Risk Score in Patients without Clinical Cardiovascular Disease

    Elizabeth George1, Thania Perez2, Nelson Perez3, Anca Askanase4 and Laura Geraldino-Pardilla5, 1Rheumatology, Columbia University College of Physicians and Surgeons, New york, NY, 2Columbia University College of Physicians & Surgeons, New York, NY, 3Hospital Regional Universitario Jose Maria Cabral y Baez, Santiago, Dominican Republic, 4Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 5Columbia University, New york, NY

     Background/Purpose: Cardiovascular disease (CVD) is a leading cause of mortality in SLE and identifying those at risk remains challenging. While in the general population the…
  • Abstract Number: 1633 • 2017 ACR/ARHP Annual Meeting

    Use of Emergency Department (ED) and Resulting Hospitalization By Patients with Systemic Lupus Erythematosus (SLE) in a Predominantly Afro-Caribbean Inner-City Cohort

    Maushmi Savjani1, Justin Levinson2 and Ellen M. Ginzler3, 1Internal Medicine, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, 2Medicine, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, 3Rheumatology, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY

    Background/Purpose: Given the complexity, chronicity and associated co-morbidities, management of SLE poses a challenge. Despite established care in private and fellow/resident clinics, our patients often…
  • Abstract Number: 1634 • 2017 ACR/ARHP Annual Meeting

    Body Mass Index and Disease Activity in Systemic Lupus Erythematosus- a Paradoxical Relationship?

    George Stojan1, Wei Fu2 and Michelle Petri3, 1Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD

    Background/Purpose: Obesity is more common in patients with SLE compared to the general population. The prevalence of obesity among SLE patients is between 28 and…
  • Abstract Number: 1635 • 2017 ACR/ARHP Annual Meeting

    Cachexia in Systemic Lupus Erythematosus- an Underrecognized Syndrome

    George Stojan1, Laurence S Magder2,3 and Michelle Petri4, 1Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Epidemiology and Public Health, Johns Hopkins University School of Medicine, Baltimore, MD, 3Epidemiology and Public health, University of Maryland School of Medicine, Baltimore, MD, 4Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD

    Background/Purpose: Cachexia is a syndrome that may accompany a range of diseases, including cancer, chronic heart failure, chronic obstructive pulmonary disease, and rheumatoid arthritis. It…
  • Abstract Number: 1636 • 2017 ACR/ARHP Annual Meeting

    Body Mass Index at Disease Onset Is Predictive of Future Organ Damage in Systemic Lupus Erythematosus

    George Stojan1, Wei Fu2 and Michelle Petri3, 1Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD

    Background/Purpose:   Obesity is more common in patients with SLE compared to the general population. The prevalence of obesity among SLE patients is between 28…
  • Abstract Number: 1637 • 2017 ACR/ARHP Annual Meeting

    Sexual Function in Married Indian Women with Systemic Lupus Erythematosus

    Benzeeta Pinto1, Sandeep Grover2, Manish Rathi3 and Aman Sharma4, 1PGIMER, CHANDIGARH, India, 2PGIMER, Chandigarh, India, 3Department of Nephrology,, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 4Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

    Background/Purpose: This study was carried out to evaluate the impact of disease activity, damage, marital satisfaction, fatigue, psychiatric comorbidity and QoL on sexual function in…
  • Abstract Number: 1638 • 2017 ACR/ARHP Annual Meeting

    High Genetic Risk Score Is Associated with Increased Organ Damage in SLE

    Sarah Reid1, Andrei Alexsson1, Martina Frodlund2, Johanna K Sandling1, Elisabet Svenungsson3, Andreas Jönsen4, Christine Bengtsson5, Iva Gunnarsson3, Anders A. Bengtsson4, Solbritt Rantapaa-Dahlqvist5, Maija-Leena Eloranta1, Ann-Christine Syvänen6, Christopher Sjöwall2, Lars Rönnblom1 and Dag Leonard1, 1Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Sweden, Uppsala, Sweden, 2Department of Clinical and Experimental Medicine, Linköping University, Sweden, Linköping, Sweden, 3Rheumatology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden, 4Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, 5Dept of Public Health and Clinical Medicine/Rheumatology, Umeå University, Sweden, Umeå, Sweden, 6Uppsala University, Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala, Sweden

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease with a complex genetic etiology. Over 80 risk genes for SLE have been identified and…
  • Abstract Number: 1639 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Evolution in a Nationwide Cohort Originally Classified As Mixed Connective Tissue Disease

    Silje Reiseter1, Ragnar Gunnarsson2, Jukka Corander3, Johanna Haydon4, May Brit Lund5 and Øyvind Molberg1, 1Oslo University Hospital, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital, Oslo, Norway, OSLO, Norway, 3Departement of Biostatistics, University of Oslo, Oslo, Norway, 4Rheumatology, Vestre Viken Hospital, Drammen, Norway, 5Respiratory Medicine, Oslo University Hospital, Oslo, Norway

    Background/Purpose: Ever since Mixed Connective Tissue Disease was presented as a distinct entity in 1972, it has been discussed whether MCTD represents an undifferentiated, transient…
  • Abstract Number: 1640 • 2017 ACR/ARHP Annual Meeting

    SLICC Damage Index Is Associated with Tubulointerstitial Nephritis on Lupus Nephritis Biopsies

    Cianna Leatherwood, Brigham and Women's Hospital, Boston, MA

    SLICC Damage Index is associated with Tubulointerstitial Nephritis on Lupus Nephritis BiopsiesKristin D’ Silva, Paul Hoover, Gearoid McMahon, Sushrut Waikar, Helmut Rennke, Karen Costenbader Background/Purpose:…
  • Abstract Number: 1641 • 2017 ACR/ARHP Annual Meeting

    Indications for Initial Renal Biopsy in Systemic Lupus Erythematosus: A Systematic Review of the Literature

    Andrew McKinnon1, Annaliese Tisseverasinghe2, Susan Barr3, Paul R. Fortin4, John G. Hanly5, Stephanie Keeling6 and Christine A. Peschken2, 1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada, 2Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 3Medicine, University of Calgary, Calgary, AB, Canada, 4Division of Rheumatology, Department of Medicine, CHU de Québec-Université Laval, Québec, QC, Canada, 5Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, 6Department of Medicine, University of Alberta, Division of Rheumatology, Edmonton, AB, Canada

    Background/Purpose: Lupus nephritis (LN) is an important cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). An initial renal biopsy (RB) is…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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