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  • Abstract Number: 1780 • 2018 ACR/ARHP Annual Meeting

    Shear Wave Elastography in the Evaluation of Submandibular Gland Characteristics in IgG4-Related Disease

    Keisuke Nishimura, Keiichiro Kadoba, Hiroki Mukoyama, Rintaro Saito, Daisuke Waki and Toshihiko Yokota, Department of Endocrinoligy and Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan

    Background/Purpose: IgG4-related disease (IgG4RD) is a chronic and systemic disease that can involve multiple organs. One of the most commonly involved organs are the salivary…
  • Abstract Number: 1781 • 2018 ACR/ARHP Annual Meeting

    Retrospective Analysis of IgG4-RD Patient Population at the Cleveland Clinic between 2007-2017

    Chan Mi Lee1, Mohamed Alalwani2, Richard Prayson1,3 and Carmen E. Gota1,4, 1Education, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, 2Hospital Medicine, Cleveland Clinic, Cleveland, OH, 3Anatomic Pathology, Cleveland Clinic, Cleveland, OH, 4Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH

    Background/Purpose: IgG4-related disease (IgG4-RD) is a rare multisystem fibro-inflammatory condition, characterized by organ mass lesions, IgG4+ lymphoplasmacytic infiltrate, and storiform fibrosis. To gain better understanding…
  • Abstract Number: 1782 • 2018 ACR/ARHP Annual Meeting

    Cigarette Smoking Is a Risk Factor for IgG4-Related Disease

    Rachel Wallwork1, Hyon K. Choi2, Cory A. Perugino3, Yuqing Zhang4, John H. Stone5 and Zachary Wallace6, 1Department of Medicine, Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 3Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 4Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, 5Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA, 6Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by tumefactive lesions that can occur at nearly any site, often associated with an elevated serum…
  • Abstract Number: 1783 • 2018 ACR/ARHP Annual Meeting

    Salivary Gland Disease in IgG4-Related Disease Is Associated with Allergic Histories

    Samantha Sanders1, Emanuel Della Torre2, Cory A. Perugino3, Aidan Long4, Hyon K. Choi4, John H. Stone5 and Zachary Wallace6, 1Harvard Medical School, Boston, MA, 2Unit of Medicine and Clinical Immunology, San Raffaele Scientific Institute, Milan, Italy, 3Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 4Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 5Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA, 6Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The etiology of IgG4-related disease (IgG4-RD) remains unknown. The role of T-helper type 2 (Th2) cells in the pathogenesis of IgG4-RD is controversial. Given…
  • Abstract Number: 1784 • 2018 ACR/ARHP Annual Meeting

    Serum IgG4 Test Characteristics: Immunonephelometry Versus Liquid Chromatography Tandem Mass Spectrometry

    Mollie Carruthers1, Andre Mattman2, Veronika Boyeva3, Liliana Cartagena4, Grace van der Gugten5, Michael Seidman2 and Luke Chen6, 1Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada, 3Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 4Mary Pack Arthritis Centre, Vancouver, BC, Canada, 5Pathology and Laboratory Medicine, St. Pauls Hospital, Vancouver, BC, Canada, 6Department of Hematology, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: IgG4-related disease (IgG4-RD) is a fibroinflammatory condition that may involve essentially any organ. The disease spectrum is also often associated with elevated serum IgG4,…
  • Abstract Number: 1785 • 2018 ACR/ARHP Annual Meeting

    A Data-Driven Approach to Guide Physicians When Considering the Differential Diagnosis of IgG4-Related Disease

    Mark A. Matza1, Zachary Wallace2 and John H. Stone3, 1Rheumatology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-Related Disease (IgG4-RD) is a chronic immune-mediated fibro-inflammatory disorder of unknown etiology.  The differential diagnosis is broad, partly because of the myriad potential organ…
  • Abstract Number: 1786 • 2018 ACR/ARHP Annual Meeting

    Favourable Response to Rituximab for the Treatment of IgG4-Related Disease: Long-Term Follow-up of 10 Patients Resistant to Glucocorticoids and Immunosuppressives

    Emin Oguz1, Gizem Dagcı2, Murat Erdugan1, Bahar Artim-Esen1, Ahmet Gül1, Lale Ocal1 and Murat Inanc3, 1Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 2Department of Internal Medicine, Istanbul Unıversity, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, İstanbul, Turkey

    Background/Purpose: Immunoglobulin G4-related disease (IgG4-RD) is a systemic, immuno-mediated fibro-inflammatory disease that affects various organ systems, with typical pathological findings and increased IgG4 levels. Glucocorticoids…
  • Abstract Number: 1787 • 2018 ACR/ARHP Annual Meeting

    How to Better Diagnose IgG4 Related Disease: a Single-Center Based Experience

    Anji Xiong1, Yuan Yang1, Beibei Cui1, Jianhong Sun1, Qibing Xie1, Yi Zhao1, Chunyu Tan1, Min Yang1, Yi Liu1, Honghu Tang1, Pingying Qing1, Lingshu Zhang1, Yubin Luo1, Yan Liang1, Ying Wang1, Yali Ye1, Ling Ma1, Shiyu Yi1 and Yi Liu2, 1Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China, 2Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, Chengdu, China

    Background/Purpose: Pathology associated with IgG4-related disease (IgG4-RD) has been described in virtually every tissue and organ of the body. The heterogeneous clinical manifestations of IgG4-RD…
  • Abstract Number: 1788 • 2018 ACR/ARHP Annual Meeting

    Predictive Factors for Work-Day Loss in a Multi-Center Study in Behcet’s Disease: Indirect Costs for Healthcare

    Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: In chronic diseases, work-day loss due to health problems is associated with indirect costs for healthcare management. The aim of this multi-center study is…
  • Abstract Number: 1789 • 2018 ACR/ARHP Annual Meeting

    Mucocutaneous Activity Index As a Patient-Reported Outcome Measure in Behcet’s Disease: A Multi-Center Study from Turkey

    Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Organ-specific patient-reported outcome (PRO) measures may help management decisions of Behcet’s disease (BD). The aim of this prospective study was to evaluate the factors…
  • Abstract Number: 1790 • 2018 ACR/ARHP Annual Meeting

    An Unmet Need for Oral Ulcer Activity in Patients with Behcet’s Disease: A Multi-National Study

    Gonca Mumcu1, Adebowale Adesanya2, Aysun Aksoy3, Joice Moraes Faria M Belem4, Natalia Borges Cardin4, Fatma Alibaz-Oner5, Tulin Ergun6, Nevsun Inanc7, Alexandre W.S. Souza8, Wafa Madanat9, Farida Fortune10 and Haner Direskeneli7, 1Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, 2Barts and The London, School of Medicine and Dentistry, Institute of Dentistry, Clinical and Diagnostic Oral Sciences, London, UK, London, United Kingdom, 3Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 4Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, 5Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Istanbul, Turkey, 6Department of Dermatology, Faculty of Medicine, Marmara University, Istanbul, Turkey, 7Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 8Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, 9Jordan’s Friends of Behcet’s disease Patients Society, Medical department, Amman, Jordan, Amman, Jordan, 10Dental Institute, Barts and The London NHS Trust, London, United Kingdom

    Background/Purpose: Efficacy of current management approaches for oral ulcer treatment in routine clinical practice is insufficiently explored in Behcet’s disease (BD) patients. The aim of…
  • Abstract Number: 1791 • 2018 ACR/ARHP Annual Meeting

    Efficacy of Apremilast for Oral Ulcers Associated with Active Behçet’s Syndrome in a Phase III Study: A Prespecified Analysis By Baseline Patient Demographics and Disease Characteristics

    Gulen Hatemi1, Alfred Mahr2, Mitsuhiro Takeno3, Do-Young Kim4, Melike Melikoglu1, Sue Cheng5, Shannon McCue5, Maria Paris5, Mindy Chen5 and Yusuf Yazici6, 1Istanbul University Cerrahpasa Medical School, Istanbul, Turkey, 2Hospital Saint-Louis, University Paris Diderot, Paris, France, 3Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 4Yonsei University College of Medicine and Severance Hospital, Seoul, Korea, Republic of (South), 5Celgene Corporation, Summit, NJ, 6New York University School of Medicine, New York, NY

    Background/Purpose: Behçet’s syndrome is a chronic, multi-system inflammatory disorder characterized by recurrent oral ulcers (OU) that can be disabling and negatively affect quality of life.…
  • Abstract Number: 1792 • 2018 ACR/ARHP Annual Meeting

    Work Productivity Is Impaired in Patients with Behcet’s Syndrome

    Nergis Serin1, Yesim Ozguler1, Sinem Nihal Esatoglu1, Vedat Hamuryudan1 and Gulen Hatemi2, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Istanbul University Cerrahpasa Medical School, Istanbul, Turkey

    Background/Purpose: Behcet’s syndrome (BS) is most active during young adulthood and working years, thus affecting productivity. Work disability was previously reported especially among BS patients…
  • Abstract Number: 1793 • 2018 ACR/ARHP Annual Meeting

    The Omeract Core Domain Set for Clinical Trials in Behçet’s Syndrome

    Gulen Hatemi1, Alexa Meara2, Yesim Ozguler3, Haner Direskeneli4, Alfred Mahr5, Beverly Shea6, Esen Cam7, Ahmet Gül8, Yusuf Yazici9, Peter Tugwell10, Hasan Yazici11 and Peter A. Merkel12, 1Istanbul University Cerrahpasa Medical School, Istanbul, Turkey, 2Internal Medicine/Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 3Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 4Rheumatology, Marmara University, School of Medicine Hospital, Istabul, Turkey, 5Hôpital Saint-Louis (Hôpitaux Universitaires Saint-Louis), Paris, France, 6Bruyere Research Institute, Ottawa, ON, Canada, 7The Univeristy of Istanbul, Istanbul, Turkey, 8Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 9New York University School of Medicine, New York, NY, 10Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada, 11Division of Rheumatology,, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 12Division of Rheumatology and the Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: There is an unmet need for reliable, validated, and widely-accepted outcome measures for clinical trials in Behçet’s syndrome (BS). The Outcome Measures in Rheumatology…
  • Abstract Number: 1794 • 2018 ACR/ARHP Annual Meeting

    Venous Vessel Wall Thickness in Lower Extremity Is Increased in Male Behcet’s Disease Patients

    Fatma Alibaz-Oner1, Rabia Ergelen2, Aydan Mutiş3, Zeynep Erturk1, Ruslan Asadov4, Tulin Ergun5 and Haner Direskeneli6, 1Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 2Marmara University School of Medicine, Radiology, ISTANBUL, Turkey, 3Marmara University, School of Medicine, Rheumatology, ISTANBUL, Turkey, 4Marmara University School of Medicine, Radiology, Istanbul, Turkey, 5Marmara University, School of Medicine, Dermatology, Istanbul, Turkey, 6Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's Disease (BD), especially in young males and is one of the…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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