ACR Meeting Abstracts

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  • Abstract Number: 1615 • 2018 ACR/ARHP Annual Meeting

    Comparative Risk of Atrial Fibrillation and Cardiovascular Events between TNF-Inhibitors and Ustekinumab in Patients with Psoriasis and Psoriatic Arthritis: A Population-Based Multi-Database Study

    Moa Lee1, Rishi J. Desai2, Yinzhu Jin3, Gregory Brill1, Alexis Ogdie4 and Seoyoung C. Kim1, 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Division of Pharmacoepidemiology and Pharmacoeconimics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 4Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Cardiovascular disease is a major comorbidity in patients with psoriasis (PsO) and psoriatic arthritis (PsA). Increasing evidence suggests a potential reduction in the risk…
  • Abstract Number: 1616 • 2018 ACR/ARHP Annual Meeting

    Region-Specific Differences in Clinical Presentation of Patients with Axial Spondyloarthritis – Results from a Large Multinational Cohort Study

    Denis Poddubnyy1, Robert D Inman2, Joachim Sieper1, Fabiana Ganz3 and Maja Hojnik4, 1Charité Universitätsmeidzin Berlin, Berlin, Germany, 2Department of Medicine, University of Toronto, Toronto, ON, Canada, 3AbbVie, Baar, Switzerland, 4AbbVie, Ljubljana, Slovenia

    Background/Purpose: There is limited evidence on the phenotypic characteristics of axial spondyloarthritis (axSpA) patients (pts) in various geographic regions around the world. This analysis aimed…
  • Abstract Number: 1617 • 2018 ACR/ARHP Annual Meeting

    Influence of Disease Activity in the Physical Activity of Psoriatic Arthritis Patients

    M. Vanesa Hernandez-Hernandez1, Hiurma Sanchez-Perez2, Esmeralda Delgado-Frías1, Iván Ferraz-Amaro3 and Federico Díaz-González4, 1Rheumatology Division, Hospital Universitario de Canarias, La Laguna, Spain, 2Rheumatology, Rheumatology Division, Hospital Universitario de Canarias, La Laguna, Spain, 3Rheumatology Division, Hospital Insular de Gran Canaria, La Laguna, Spain, 4University of La Laguna, Hospital Universitario de Canarias, La Laguna, Spain

    Background/Purpose: It is generally assumed that patients with chronic arthritis conditions tend to exercise less than what is currently recommended. Although several evidences support this…
  • Abstract Number: 1618 • 2018 ACR/ARHP Annual Meeting

    Adipose Tissue Inflammation in Psoriatic Arthritis: Overexpression of a Wide Array of Inflammatory Mediators and Associations with Disease and Treatment Characteristics

    Jae Hee Yun1, Robert Winchester2, Hui-Zhu Zhang2, Christopher Depender1 and Jon T. Giles1, 1Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose: Obesity is associated with PsA risk, severity, and lack of response to DMARDs.  However, no studies have explored adipose tissue inflammation at the molecular…
  • Abstract Number: 1619 • 2018 ACR/ARHP Annual Meeting

    Patterns and Outcomes on As Patients Disease Activity Using Smart System of Disease Management (SSDM): Analysis of T2T Pattern Shift and the Correlation between Disease Activity and Mental Health

    Jing Xue1, Hui Song2, Jing Yang3, Zhenchun Zhang4, Chun Li5, Hongbin Li6, Zhenbiao Wu7, Hua Wei8, Jianlin Huang9, Hongzhi Wang10, Yasong Li11, Xiaohan Wang12, Henglian Wu13, Miaojia Zhang14, Yuhua Jia15, Hui Xiao15, Fei Xiao15 and Huaxiang Wu16, 188 Jiefang Road, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China, 2Department of Rheumatology, Beijing Jishuitan Hospital, Beijing, China, 3Department of rheumatology, Central Hospital of MianYang, Sichuan, Mian Yang, China, 4People's Hospital of Linyi, Shandong, Linyi, China, 5Peking University People's Hospital, Beijing, China, 6The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China, 7The First Affiliated Hospital of The Fourth Military Medical University, Xi'an, China, 8Northern Jiangsu People's Hospital, Yangzhou, China, 9Department of rheumatology, The Sixth Hospital Affiliated to Sun yat-sen University, Guangzhou, China, 10The First Hospital of Jiaxing, Jiaxing, China, 11Department of Rheumatology and Immunology, Zhejiang Provincal People's Hospital, Hangzhou, China, 12Department of Rheumatology and Immunology, Anyang district hospital, Anyang, China, 13Dongguan Donghua Hospital, Dongguan, China, 14Department of Rheumatology and Immunology, Jiangsu Province Hospital, Nanjing, China, 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China, 16The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China

    Background/Purpose: Ankylosing Spondylitis Disease Activity Score (ASDAS) was adopted to evaluate the degree of disease activity and the inflammatory response in AS patients. ASDAS score…
  • Abstract Number: 1620 • 2018 ACR/ARHP Annual Meeting

    Lateral DXA More Effective in Detecting Osteoporosis Than Conventional DXA in Axial Spondyloarthropathy

    Gillian Fitzgerald1,2, Jason Wyse3, Tochukwu Anachebe4, Ronan Mullan5, David Kane6, Kevin McCarroll7 and Finbar O' Shea2, 1School of Medicine, Trinity College Dublin, Dublin 2, Ireland, 2Rheumatology, St. James's Hospital, Dublin 8, Ireland, 3School of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland, 4Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, 5Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, 6Department of Rheumatology, Tallaght Hospital, TCD, Dublin 24, Ireland, 7Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland

    Background/Purpose: The severe consequences of osteoporosis in the general population are well outlined. In axial spondyloarthropathy (axSpA), osteoproliferation of the spine means posterioanterior (PA) dual-energy…
  • Abstract Number: 1621 • 2018 ACR/ARHP Annual Meeting

    Higher Serum Uric Acid Levels Protect Against Osteoporosis in Patients with Axial Spondyloarthropathy

    Gillian Fitzgerald1,2, Tochukwu Anachebe3, Ronan Mullan4, David Kane5, Kevin McCarroll6 and Finbar O' Shea2, 1School of Medicine, Trinity College Dublin, Dublin 2, Ireland, 2Rheumatology, St. James's Hospital, Dublin 8, Ireland, 3Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, 4Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, 5Department of Rheumatology, Tallaght Hospital, Dublin 24, Ireland, 6Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland

    Background/Purpose: High serum urate (SUA) is a risk factor for metabolic disease, including hypertension and coronary artery disease. However, SUA has an antioxidant effect and…
  • Abstract Number: 1622 • 2018 ACR/ARHP Annual Meeting

    ASAS Consensus on Spanish Nomenclature for Spondyloarthritis

    Victoria Navarro-Compán1, Teresa Oton-Sanchez2, Estibaliz Loza3, Raquel Almodóvar González4, Rafael Ariza5, Wilson Bautista-Molano6, Rubén Burgos-Vargas7, Eduardo Collantes Estevez8, Eugenio De Miguel9, Carlos M Gonzalez10, Jordi Gratacos-Masmitja11, Sebastián Ibáñez12, Xavier Juanola13, José A. Maldonado-Cocco14, Anna Molto15, Juan D. Mulero16, Cesar Pacheco-Tena17, Cesar Ramos-Remus18, Jesus Sanz19, Rafael Valle-Oñate20, Pedro Zarco21 and Helena Marzo-Ortega22, 1Immuno-Rheumatology research group, IdiPaz. La Paz University Hospital, Madrid, Spain, 2InMusc. Instituto de Salud Músculo-Esquelética, Madrid, Spain, 3INMUSC, Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, 4Rheumatology, Hospital Universitario Fundación Alcorcón. Madrid. Spain, Madrid, Spain, 5Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, 6Hospital Militar, Bogotá, Colombia, 7Department of Rheumatology, Hospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico, 8IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 9Rheumatology, University Hospital La Paz, IdiPaz, Madrid, Spain, 10Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 11Rheumatology, Hospital Parc Taulí, Sabadell - Barcelona, Spain, 12Rheumatology Department, Clínica Alemana de Santiago, Santiago, Chile, 13Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 14Buenos Aires University, Consulting Professor of Rheumatology, Buenos Aires University. Argentina, Buenos Aires, Argentina, 15Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, 16Hospital Puerta de Hierro, Majadahonda, Madrid, Spain, 17Universidad Autónoma de Chihuahua, Hospital Christus Muguerza del Parque, Chihuahua, Mexico, 18Universidad Autonoma de Guadalajara, Zapopan, Mexico, 19Rheumatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 20Unidad de Reumatologia, Hospital Militar, Bogota, Colombia, 21H Fundación Alcorcón, Alcorcón, Spain, 22NIHR LBRC, LTHT and LIRMM, UoL, Leeds, United Kingdom

    Background/Purpose: In the last three decades, major advances in the spondyloarthritis (SpA) field have been achieved leading to new terminology. Whilst this terminology is well…
  • Abstract Number: 1623 • 2018 ACR/ARHP Annual Meeting

    Insight into the Quality of Life of Patients with Ankylosing Spondylitis: Real-World Data from a US-Based Life Impact Survey

    James T. Rosenbaum1, Lisa Pisenti2, Yujin Park3 and Richard Howard4, 1Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, 2UCB, Inc., Smyrna, GA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Spondylitis Association of America, Van Nuys, CA

    Background/Purpose: While severe pain and stiffness are common hallmarks of ankylosing spondylitis (AS), disease progression is slow and not always visible; however, the quality of…
  • Abstract Number: 1624 • 2018 ACR/ARHP Annual Meeting

    Real-World Insight into the Disease Burden and Treatment of Spondyloarthritis from a US-Based Life Impact Survey

    James T. Rosenbaum1, Lisa Pisenti2, Yujin Park3 and Richard Howard4, 1Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, 2UCB, Inc., Smyrna, GA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Spondylitis Association of America, Van Nuys, CA

    Background/Purpose: Spondyloarthritis (SpA) is a group of chronic, inflammatory diseases associated with severe pain in the joints and entheses. There is limited evidence on real-world…
  • Abstract Number: 1625 • 2018 ACR/ARHP Annual Meeting

    Association of HLA-B Type and Sacroiliitis in Patients with Psoriatic Arthritis

    Daniel Kuo1, Isela Valera2, Mihaela Taylor1, Roy Altman1, Veena K. Ranganath1, Thanda Aung1, James Louie1 and Suzanne Kafaja1, 1Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Autoimmunity and Tolerance Laboratory, Division of Rheumatology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease with strong genetic heritability. Class I major histocompatibility complex (MHC) genes have been associated with PsA phenotype…
  • Abstract Number: 1626 • 2018 ACR/ARHP Annual Meeting

    The Disease Expression in Familial and Sporadic Axial Spondyloarthritis Patients

    Dilek Solmaz1, Onay Gercik2, Gökhan Kabadayı1 and Servet Akar3, 1Rheumatology, Izmir Katip Celebi University, Faculty of Medicine, Izmir, Turkey, 2Rheumatology, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 3Faculty of Medicine, Department of Rheumatology, Izmir Katip Celebi University, Izmir, Turkey

    Background/Purpose: Familial aggregation of the SpA in particular AS has long been known and up to 40% of AS patients have a positive family history…
  • Abstract Number: 1627 • 2018 ACR/ARHP Annual Meeting

    Assessment of Myocardial Dysfunction Using Speckle Tracking Echocardiography in Patients with Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

    Volkan Emren1, Onay Gercik2, Emre Ozdemir3, Dilek Solmaz2, Nihan Eren3, Mehmet Tokac3, Gökhan Kabadayı2, Sercan Gucenmez2 and Servet Akar4, 1Faculty Of Medicine, Department of Cardiology, Izmir Katip Celebi University, Izmir, Turkey, 2Rheumatology, Izmir Katip Celebi University, Faculty of Medicine, Izmir, Turkey, 3Faculty Of Medicine, Department Of Cardiology, Izmir Katip Celebi University, Izmir, Turkey, 4Faculty of Medicine, Department of Rheumatology, Izmir Katip Celebi University, Izmir, Turkey

    Background/Purpose: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that mainly affects axial skeleton. Although some differences like sex and objective signs of inflammation were…
  • Abstract Number: 1628 • 2018 ACR/ARHP Annual Meeting

    Is Axial Psoriatic Arthritis Distinct from Ankylosing Spondylitis with and without Concomitant Psoriasis?

    Joy Feld1, Justine Y. Ye2, Vinod Chandran2, Robert D Inman3, Nigil Haroon4, Richard J. Cook5 and Dafna D Gladman1, 1Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 4Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, 5Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Spondyloarthritis include two major phenotypes: ankylosing spondylitis (AS) and psoriatic arthritis (PsA). 10% of AS patients have concomitant psoriasis, while 25% - 70% of…
  • Abstract Number: 1629 • 2018 ACR/ARHP Annual Meeting

    Hyperlipoproteinemia (a) in Patients with Spondyloarthritis. Results of the CARMA Study

    María Carmen García-Gómez1, Maria Auxiliadora Martin2, Cristina Fernández-Carballido3, Santos Castañeda4, Carlos González-Juanatey5, Fernando Sánchez-Alonso6, María José González-Fernández7, Raimon Sanmarti8, Alberto Garcia-Vadillo9, Benjamin Fernandez Gutierrez10, Miriam García-Arias11, Javier Manero12, José Miguel Senabre13, Amalia Rueda Cid14, Sergio Ros Expósito15, José Manuel Pina Salvador16, Alba Erra Durán17, Ingrid Moller18, Javier Llorca19 and Miguel Angel González-Gay20, 1Rheumatology Division, Consorci Sanitari de Terrassa, Terrassa (Barcelona), Spain, 2Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 3Rheumatology Division, Hospital General Universitario de Elda, Elda, Spain, 4Rheumatology, Hospital La Princesa. Madrid. Spain, Madrid, Spain, 5Division of Cardiology, Hospital Universitario Lucus Augusti, Lugo, Spain, 6Unidad de Investigación, Spanish Society of Rheumatology, Madrid, Spain, 7Rheumatology, Institut Dexeus, Barcelona, Spain, 8Rheumatology Service, Hospital Clinic, Barcelona, Spain, 9Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 10Rheumatology Department, Hospital Clínico San Carlos, Madrid, Spain, 11Hospital Universitario de la Princesa. Madrid. Spain, Madrid, Spain, 12Ophthalmology and Rheumatology, Hospital Miguel Servet. Zaragoza. Spain, Zaragoza, Spain, 13Rheumatology, Hospital Marina Baixa, Alicante, Spain, 14Rheumatology, Hospital General de Valencia, Valencia, Spain, 15Rheumatology, Hospital de Viladecans, Barcelona, Spain, 16Rheumatology, Hospital de Barbastro, Huesca, Spain, 17Rheumatology, Hospital de Sant Rafael, Barcelona, Spain, 18Instituto de Poal, Barcelona, Spain, 19Division of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, Santander, Spain, 20School of Medicine, University of Cantabria, Santander, Spain, Santander, Spain

    Background/Purpose: Cardiovascular disease (CVD) is one of the main cause of mortality and morbidity in patients with spondyloarthritis (SpA), partially explained by traditional CV risk…
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