Abstracts Archive - Page 1291 of 2425 - ACR Meeting Abstracts

Abstract Number: 1282 • 2017 ACR/ARHP Annual Meeting
Assessing the Prevalence of Juvenile Systemic Sclerosis in Childhood Using Administrative Claims Data from the United States
Ivan Foeldvari¹, Timothy Beukelman² and Fenglong Xie³, ¹Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ²Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Juvenile systemic Sclerosis (jSSc) is an orphan disease. There are some data regarding the incidence, but nearly no data exist regarding the prevalence of…
Abstract Number: 1283 • 2017 ACR/ARHP Annual Meeting
Male Patients Have a More Severe Course As Female Patients with Diffuse Juvenile Systemic Scleroderma? Results from the Juvenile Scleroderma Inception Cohort Www.Juvenile-Scleroderma.Com
Ivan Foeldvari¹, Jens Klotsche², Ozgur Kasapcopur³, Amra Adrovic⁴, Valda Stanevicha⁵, Maria Teresa Terreri⁶, Ekaterina Alexeeva⁷, Maria M. Katsicas⁸, Vanessa Smith⁹, Rolando Cimaz¹⁰, Mikhail Kostik¹¹, Thomas J. A. Lehman¹², Jordi Anton¹³, Walter A. Sifuentes-Giraldo¹⁴, Flavio Sztajnbok¹⁵, Tadey Avcin¹⁶, Mahesh Janarthanan¹⁷, Maria José Santos¹⁸, Dana Nemkova¹⁹, Cristina Battagliotti²⁰, Despina Eleftheriou²¹, Liora Harel²², Tilmann Kallinich²³, K Minden²⁴, Susan Mary Nielsen²⁵, Kathryn S. Torok²⁶, Yosef Uziel²⁷, Anne Stevens²⁸, Clarissa Pilkington²⁹ and Nicola Helmus¹, ¹Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ²Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, ³Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ⁴Department of Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey, ⁵Pediatric cathedra, Riga Stradiņš University, Riga, Latvia, ⁶Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo, Brazil, ⁷Children's Health of RAMS and IM Sechenov First Moscow State Medical University, Moscow, Russian Federation, ⁸Service of Immunology & Rheumatology., Hospital de Pediatría Prof Dr JP Garrahan, Buenos Aires, Argentina, ⁹Faculty of Internal Medicine, Ghent University, Ghent, Belgium, ¹⁰Pediatrics, Ospedale Pediatrico Anna Meyer, Florence, Italy, ¹¹Hospital Pediatrics, State Pediatric Medical University, Saint-Petersburg, Russia, ¹²Pediatric Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ¹³pediatric Rheumatology, University Childrenxs Hospital, Barcelona, Spain, ¹⁴Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, ¹⁵Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, ¹⁶University Children's Hospital, Ljubljana, Slovenia, ¹⁷Pediatric Rheumatology, Chennai, India, ¹⁸Reuma.pt, Almada, Portugal, Almada, Portugal, ¹⁹Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, General University Hospital in Prague, Prague, Czech Republic, ²⁰Hospital de Niños Dr Orlando Alasia, Santa Fé, Argentina, ²¹Infection, Inflammation and Rheumatology, UCL Institute of Child Health, London, United Kingdom, ²²Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, ²³Charité, Humbolt University Medicine Berlin, Berlin, Germany, ²⁴Charité – University of Medicine Berlin, Berlin, Germany, ²⁵Rigshospitalet, Copenhagen, Denmark, ²⁶Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ²⁷Meir Medical Center, Kfar Saba, Israel, ²⁸University of Washington, Department of Pediatrics, Seattle, WA, ²⁹Paediatric Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Background/Purpose: In adult systemic scleroderma patients male have a more sever course. This issue was never evaluated in a larger juvenile scleroderma cohort. Methods: Patients…
Abstract Number: 1284 • 2017 ACR/ARHP Annual Meeting
The Localized Scleroderma Quality of Life Instrument (LoSQI): Initial Validation in Pediatric Localized Scleroderma
Christina K. Zigler¹, Kaveh Ardalan², Kaila Schollaert-Fitch³, Heidi Jacobe⁴ and Kathryn S. Torok³, ¹Physical Medicine & Rehabilitation, University of Pittsburgh, Pittsburgh, PA, ²Division of Rheumatology, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, ³Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX
Background/Purpose: There is a current need to integrate health related quality of life (HRQoL) into outcomes for clinical trials (Chang & Reeve, 2005). For pediatric…
Abstract Number: 1285 • 2017 ACR/ARHP Annual Meeting
Extracutaneous Involvement Is Common in Juvenile Localized Scleroderma and Associated with a Higher Level of Perceived Disease Impact
Suzanne C. Li¹, Tracy Andrews², Mallory Chen³, Kathryn S. Torok⁴, Elena Pope⁵, Katie G. Stewart⁶, Gloria C. Higgins⁷, C. Egla Rabinovich⁸, Ronald M. Laxer⁹, Kathleen Haines¹⁰, Marilynn Punaro¹¹, Heidi Jacobe¹² and Kathleen O'Neil¹³, ¹Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack Meridian Health, Hackensack, NJ, ²Research, Hackensack University Medical Center, Hackensack Meridian Health, Hackensack, NJ, ³Williams College, williamstown, MA, ⁴Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ⁵Section of Dermatology, The Hospital for Sick Children, Hospital for Sick Children, Toronto, ON, Canada, ⁶Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ⁷Pediatric Rheumatology Ohio State University, Nationwide Childrens Hospital, Columbus, OH, ⁸Pediatric Rheumatology, Duke University Medical Center, Durham, NC, ⁹Div of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁰Joseph M Sanzari Children’s Hospital, Hackensack Meridian Health, Hackensack, NJ, ¹¹Texas Scottish Rite Hospital for Children, Dallas, TX, ¹²Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, ¹³Pediatric Rheumatology, RIley Hospital for Children, Indianapolis, IN
Background/Purpose: Juvenile localized scleroderma (jLS) is often associated with deep tissue and extracutaneous involvement (ECI), putting children at risk for severe morbidity such as hemiatrophy,…
Abstract Number: 1286 • 2017 ACR/ARHP Annual Meeting
Performance of Juvenile Scleroderma Classification Criteria for Juvenile Systemic Sclerosis. Results from the Jssc Inception Cohort
Jens Klotsche¹, Ivan Foeldvari², Ozgur Kasapcopur³, Vanessa Smith⁴, Flavio Sztajnbok⁵, Maria M. Katsicas⁶, Rolando Cimaz⁷, Mahesh Janarthanan⁸, Jordi Anton⁹, Mikhail Kostik¹⁰, Dana Nemkova¹¹, Walter A. Sifuentes-Giraldo¹², Valda Stanevicha¹³, Kathryn S. Torok¹⁴, Simone Appenzeller¹⁵, Tadey Avcin¹⁶, Lillemor Berntson¹⁷, Liora Harel¹⁸, Tilmann Kallinich¹⁹, Maria José Santos²⁰, Maria Teresa Terreri²¹, Yosef Uziel²² and Nicola Helmus², ¹Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, ²Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ³Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ⁴Faculty of Internal Medicine, Ghent University, Ghent, Belgium, ⁵Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, ⁶Service of Immunology & Rheumatology., Hospital de Pediatría Prof Dr JP Garrahan, Buenos Aires, Argentina, ⁷Pediatrics, Ospedale Pediatrico Anna Meyer, Florence, Italy, ⁸Pediatric Rheumatology, Chennai, India, ⁹pediatric Rheumatology, University Childrenxs Hospital, Barcelona, Spain, ¹⁰Hospital Pediatrics, State Pediatric Medical University, Saint-Petersburg, Russia, ¹¹Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, General University Hospital in Prague, Prague, Czech Republic, ¹²Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, ¹³Pediatric cathedra, Riga Stradiņš University, Riga, Latvia, ¹⁴Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ¹⁵Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil, ¹⁶University Children's Hospital, Ljubljana, Slovenia, ¹⁷Dept. of Pediatrics, Uppsala University Hospital, Uppsala, Sweden, ¹⁸Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, ¹⁹Charité, Humbolt University Medicine Berlin, Berlin, Germany, ²⁰Reuma.pt, Almada, Portugal, Almada, Portugal, ²¹Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo, Brazil, ²²Meir Medical Center, Kfar Saba, Israel
Background/Purpose: Juvenile systemic sclerosis (jSSc) is a rare disease during childhood. Classification criteria for jSSc were published in 2007. They include a major criterion that…
Abstract Number: 1287 • 2017 ACR/ARHP Annual Meeting
Cone Beam Computed Tomography for the Assessment of Linear Scleroderma of the Face
Francesco Zulian¹, Chiara Di Giovanni², Stafano Puggina³, Alessandra Meneghel¹, Sabina Trainito⁴ and Giorgia Martini², ¹University of Padua, Department of Woman and Child Health, Padua, Italy, ²Department of Woman and Child Health, University of Padua, Padua, Italy, ³Unix Radiology Service, Affidea Group inc., Piove di Sacco, Italy, ⁴Division of Physical Medicine and Rehabilitation, University of Padua, Padua, Italy
Background/Purpose: Linear scleroderma of the face (LSF) is a very disabling condition and, to date, standardized and validated methods for assessing and monitoring the disease…
Abstract Number: 1288 • 2017 ACR/ARHP Annual Meeting
Renal Disease Course in Pediatric Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis in the First 12-Months – a Pediatric Vasculitis Initiative (PedVas) Study
Kimberly Morishita¹, Audrea Chen², Cherry Mammen¹, Angelyne Rivera³ and David Cabral¹, ¹BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ²Medicine, University of British Columbia, Vancouver, BC, Canada, ³Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Renal disease is the most common manifestation of pediatric anti-neutrophil cycloplasmic antibody (ANCA) associated vasculitis (AAV). Renal disease course and early trajectories have not…
Abstract Number: 1289 • 2017 ACR/ARHP Annual Meeting
Assessing ACR/EULAR Provisional 2017 Classification Criteria for Granulomatosis with Polyangiitis (GPA) in a Cohort of 376 Children with Small to Medium Vessel Chronic Vasculitis – a Pediatric Vasculitis Initiative (PedVas) Study
Angelyne Rivera¹, Kimberly Morishita², David Cabral² and Raashid Luqmani³, ¹Pediatrics, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ²BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ³Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
Background/Purpose: Classification of chronic vasculitis to clinically or etiologically meaningful groups has been challenging. In 2008, the 1990 ACR classification criteria for GPA was adapted…
Abstract Number: 1290 • 2017 ACR/ARHP Annual Meeting
Preterm Birth Phenotypes in Women with Autoimmune Diseases
Kathleen D. Kolstad¹, Jonathan A. Mayo², Lorinda Chung³, Yashaar Chaichian⁴, Victoria M. Kelly⁵, Maurice Druzin⁶, David K. Stevenson⁷, Gary M. Shaw⁸ and Julia F Simard⁹, ¹Rheumatology, Stanford University Medical Center, Stanford, CA, ²Stanford University Medical Center, Stanford, CA, ³Rheumatology, Stanford University Medical Center, Palo Alto, CA, ⁴Medicine, Immunology & Rheumatology Division, Stanford School of Medicine, Stanford, CA, ⁵Palo Alto Medical Foundation, Palo Alto, CA, ⁶Obstetrics & Gynecology, Stanford School of Medicine, Stanford, CA, ⁷Pediatrics - Neonatology, Stanford University, Stanford, CA, ⁸Pediatrics, Division of Neonatology and Developmental Medicine, Stanford School of Medicine, Stanford, CA, ⁹Division of Epidemiology, Health Research and Policy Department, Stanford School of Medicine, Stanford, CA
Background/Purpose: Systemic autoimmune diseases expose patients to chronic inflammation, immune dysregulation, and vascular abnormalities; complications that can impact obstetric outcomes. The goal of this study…
Abstract Number: 1291 • 2017 ACR/ARHP Annual Meeting
Preterm Delivery Phenotypes in SLE Pregnancies
Julia F Simard¹, Yashaar Chaichian², Marios Rossides³, Anna-Karin Wikstrom⁴, Gary M. Shaw⁵ and Maurice Druzin⁶, ¹Medicine, Division of Immunology & Rheumatology, Stanford School of Medicine, Stanford, CA, ²Medicine, Immunology & Rheumatology Division, Stanford School of Medicine, Stanford, CA, ³Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, ⁴Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden, ⁵Pediatrics, Division of Neonatology and Developmental Medicine, Stanford School of Medicine, Stanford, CA, ⁶Obstetrics & Gynecology, Stanford School of Medicine, Stanford, CA
Background/Purpose: Women with systemic lupus erythematosus (SLE) are at greater risk of preterm delivery compared to women without lupus. A significant proportion of SLE pregnancies…
Abstract Number: 1292 • 2017 ACR/ARHP Annual Meeting
Long-Term Follow-up of 320 Chilren Born to Mothers with Systemic Autoimmune Diseases: A Multicentre Survey from 24 Rheumatology Centers in Italy
Maria Grazia Lazzaroni¹, Cecilia Nalli¹, Laura Andreoli¹, Chiara Carini¹, Marilia Rodrigues², Francesca Dall'Ara¹, Elena Bartoloni-Bocci³, Roberto Gerli³, Maria Gerosa⁴, Cecilia B. Chighizola⁵, Pier Luigi Meroni⁴, Luigi Sinigaglia⁶, Paola Conigliaro⁷, Roberto Perricone⁷, Ada Corrado⁸, Francesco Paolo Cantatore⁸, Salvatore D'Angelo⁹, Ignazio Olivieri⁹, Maria Favaro¹⁰, Maddalena Larosa¹⁰, Andrea Doria¹⁰, Amelia Ruffatti¹¹, Elena Generali¹², Carlo Selmi¹³, Marianna Meroni¹⁴, Maurizio Cutolo¹⁵, Melissa Padovan¹⁶, Marcello Govoni¹⁶, Giulia Pazzola¹⁷, Carlo Salvarani¹⁸, Susanna Peccatori¹⁹, Giuseppe Paolazzi¹⁹, Imma Prevete²⁰, Giovanni Minisola²⁰, Gian Domenico Sebastiani²¹, Antonio Brucato²², Véronique Ramoni²³, Roberto Caporali²⁴, Carlomaurizio Montecucco²⁴, Viola Signorini²⁵, Chiara Tani²⁶, Marta Mosca²⁵, Marica Trevisani²⁷, Nazzarena Malavolta²⁷, Marta Vadacca²⁸, Antonella Afeltra²⁹, Ester Vivaldelli³⁰, Armin Maier³⁰, Elisa Visalli³¹, Rosario Foti³¹, Carolina Benigno³², Lucia Zuliani³³, Armando Gabrielli³³, Corrado Campochiaro³⁴, Elena Baldissera³⁵, Maria Grazia Sabbadini³⁶, Nicoletta Romeo³⁷ and Angela Tincani¹, ¹University and Spedali Civili of Brescia, Brescia, Italy, ²Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ³University and Azienda Ospedaliera of Perugia, Perugia, Italy, ⁴Istituto Ortopedico Gaetano Pini, University of Milan, Milano, Italy, ⁵Rheumatology, Istituto Auxologico Italiano, University of Milan, Cusano Milanino, Italy, ⁶Istituto Ortopedico Gaetano Pini, University of Milan, Italy, Milan, Italy, ⁷Policlinico Tor Vergata of Rome, Rome, Italy, ⁸Ospedali Riuniti of Foggia, Foggia, Italy, ⁹San Carlo Hospital of Potenza, Potenza, Italy, ¹⁰University and Azienda Ospedaliera of Padova, Padova, Italy, ¹¹Unità di Reumatologia, Dipartimento di Medicina-DIMED, Università di Padova., Padova, Italy, ¹²Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano (MI), Italy, ¹³Humanitas Research Hospital of Milan, Rozzano, Italy, ¹⁴Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genova, Italy, ¹⁵Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genoa, Italy, ¹⁶UOC of Rheumatology, University Hospital S. Anna, Cona Ferrara, Italy, ¹⁷Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico of Reggio-Emilia, Reggio-Emilia, Italy, ¹⁸Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy, ¹⁹Azienda Provinciale Servizi Sanitari of Trento, Trento, Italy, ²⁰Azienda Ospedaliera San Camillo of Rome, Roma, Italy, ²¹Rheumatology, San Camillo Forlanini Hospital, Roma, Italy, ²²Struttura Complessa Medicina Interna, ASST Papa Giovanni XXIII, Bergamo, Italy, ²³Ospedale Papa Giovanni XXIII of Bergamo, Policlinico San Matteo of Pavia, Bergamo, Pavia, Italy, ²⁴University and Policlinico San Matteo of Pavia, Pavia, Italy, ²⁵University of Pisa, Pisa, Italy, ²⁶Rheumatology Unit, University of Pisa, Pisa, Italy, ²⁷Policlinico S.Orsola-Malpighi, Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy, ²⁸University Campus Biomedico of Rome, Roma, Italy, ²⁹University Campus Biomedico of Rome, roma, Italy, ³⁰Ospedale of Bolzano, Bolzano, Italy, ³¹Policlinico Vittorio Emanuele-Ferrarotto-Bambin Gesù of Catania, Catania, Italy, ³²University Federico II of Napoli, Napoli, Italy, ³³Ospedali Riuniti of Ancona, Ancona, Italy, ³⁴Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, London, United Kingdom, ³⁵Ospedale San Raffaele of Milan, Milan, Italy, ³⁶Unit of Medicine and Clinical Immunology, Ospedale San Raffaele of Milano, Milan, Italy, ³⁷Ospedale S.Croce e Carle of Cuneo, Cuneo, Italy
Background/Purpose: Rheumatic Diseases (RD) frequently affect women during reproductive age, therefore counseling on family planning is crucial for their quality of life. Children's outcome is…
Abstract Number: 1293 • 2017 ACR/ARHP Annual Meeting
Indications for Cesarean Delivery in Systemic Lupus Erythematosus Pregnancies
Evelyne Vinet¹, Paul R. Fortin², Stéphanie Roberge³, Emmanuel Bujold⁴ and Nils Chaillet⁵, ¹Divisions of Rheymatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ²Infectious Diseases and Immunity Research Division, CHU de Québec-Université Laval Research Center, Québec, QC, Canada, ³Centre de recherche du CHU de Québec-Université Laval, Québec, QC, Canada, ⁴Reproduction, mother and youth health, Centre Hospitalier de l'Université Laval (CHUL), Québec, QC, Canada, ⁵Département d’obstétrique et gynécologie et département de Médecine de famille et médecine d’urgence, Université de Sherbrooke, Sherbrooke, QC, Canada
Background/Purpose: Pregnant SLE women are at increased risk of cesarean delivery compared to pregnant women from the general population. Yet, to date, no one has…
Abstract Number: 1294 • 2017 ACR/ARHP Annual Meeting
Time to Pregnancy in Women with Systemic Lupus Erythematosus
Meriem El bakali¹, Sasha Bernatsky², Christian A. Pineau³ and Evelyne Vinet⁴, ¹Division of Rheumatology, McGill University Health Centre, Montreal, QC, Canada, ²Divisions of Rheumatology and Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³McGill University Health Centre, Montreal, QC, Canada, ⁴Divisions of Rheymatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Women diagnosed with systemic lupus erythematosus (SLE) during the reproductive period have fewer children than unaffected women. Multiple disease-related factors might influence family size…
Abstract Number: 1295 • 2017 ACR/ARHP Annual Meeting
Pregnancy Outcome in Patients with SLE Compared to Patients with Other Inflammatory Rheumatic Diseases: Real World Data from a Prospective Pregnancy Register
Rebecca Fischer-Betz¹, Christina Bungartz², Matthias Schneider¹, Jutta Richter¹, Anja Weiss², Angela Zink³ and Anja Strangfeld⁴, ¹Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ²German Rheumatism Research Center, Berlin, Germany, ³Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany, ⁴Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: SLE pregnancies are complicated due to risk for maternal disease exacerbation and potential for fetal and neonatal complications. With careful pre-pregnancy counseling and monitoring…
Abstract Number: 1296 • 2017 ACR/ARHP Annual Meeting
Hydroxychloroquine Level Decreases throughout Pregnancy: Implications for Maternal and Neonatal Outcomes
Stephen Balevic¹, Michael Cohen-Wolkowiez², Amanda M. Eudy³, Laura E. Schanberg⁴ and Megan E. B. Clowse⁵, ¹Rheumatology, Adult and Pediatric, Duke University Medical Center, Durham, NC, ²Pharmacometrics Center, Duke Clinical Research Institute, Durham, NC, ³Duke University Medical Center, Chapel Hill, NC, ⁴Pediatrics, Duke University Medical Center, Durham, NC, ⁵Duke University Medical Center, Durham, NC
Background/Purpose: Pregnancies in women with active rheumatic disease often result in poor neonatal outcomes. Prior data suggests that hydroxychloroquine (HCQ) can reduce disease activity and…

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