Abstract Number: 1570 • 2018 ACR/ARHP Annual Meeting
Clinical Utility of a Second Minor Salivary Gland Biopsy in Patients with Suspected Sjögren’s Syndrome: A Retrospective Cohort Study
Background/Purpose: To determine whether the repetition of minor salivary gland biopsy (MSGB) has a clinical diagnostic utility in patients with suspicion of primary Sjögren’s syndrome…Abstract Number: 1571 • 2018 ACR/ARHP Annual Meeting
RNA Sequencing Detection of Gene Dysregulation in Epithelial Cells Sorted from Salivary Gland Tissue Reveals Interesting Pathways Involved in Primary Sjögren’s Syndrome Pathophysiology
Background/Purpose: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder characterized by lymphocytic infiltrates and destruction of the salivary glands. Several lines of evidence support…Abstract Number: 1572 • 2018 ACR/ARHP Annual Meeting
Salivary Flow Rates and Oral Health Related Quality of Life Are Associated with Ultrasonographic Scoring of the Major Salivary Glands in Sjogren Syndrome
Background/Purpose: Ultrasonography (USG) of major salivary glands (SG-USG) as a non-invasive method is widely used to evaluate salivary gland involvement in Sjogren’s syndrome (SjS). Since…Abstract Number: 1573 • 2018 ACR/ARHP Annual Meeting
Salivary Dysbiosis Correlates with Clinical Status of Anti-Ro Positive Mothers of Children with Neonatal Lupus
Background/Purpose: Neonatal lupus is linked to the presence of circulating anti-Ro antibodies in the mother. These antibodies are present in asymptomatic individuals, who in a…Abstract Number: 1574 • 2018 ACR/ARHP Annual Meeting
Autoantibodies Present in Saliva from Sjogren’s Syndrome and Non-Sjogren’s Sicca Patients Are Not Detectible in Serum
Background/Purpose: There is evidence for B cell involvement in the pathogenesis of Sjögren’s syndrome by the presence of autoantigen-specific B cells. Autoantibodies toward Ro/SSA and…Abstract Number: 1575 • 2018 ACR/ARHP Annual Meeting
The Association between Salivary Gland Ultrasonography and Clinical Manifestation in Patients with Early Primary Sjögren’s Syndrome
Background/Purpose: To investigate the clinical manifestations in patients with early primary Sjögren¡¦s syndrome based on different severity score under salivary gland ultrasonography.Methods: We enrolled 44…Abstract Number: 1576 • 2018 ACR/ARHP Annual Meeting
Soluble Semaphorin 4D/CD100 Is Increased in the Saliva of Sjögren’s Syndrome
Background/Purpose: Sjögren’s syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration in exocrine organs with dry mouth and dry eyes. Semaphorin 4D (SEMA4D) /…Abstract Number: 1577 • 2018 ACR/ARHP Annual Meeting
Soluble Siglec-5 Is a Novel Salivary Biomarker for Primary Sjogren’s Syndrome
Background/Purpose: Despite advances in the understanding of the pathogenesis, disease-specific biomarkers have not been included in the classification criteria for Primary Sjogren's syndrome (pSS). Based…Abstract Number: 1578 • 2018 ACR/ARHP Annual Meeting
Exercise Increases Aerobic Capacity in Primary Sjögren´s Syndrome: A Randomized Controlled Trial
Background/Purpose: Recent studies have shown increased cardiovascular risk in patients with primary Sjögren's syndrome (pSS). As physical exercise is one of the pillars in primary…Abstract Number: 1579 • 2018 ACR/ARHP Annual Meeting
Sjögren’s Syndrome Is Associated with Reduced Sex Hormone Exposure: A Case-Control Study
Background/Purpose: Sjögren’s Syndrome (SS) is an autoimmune disease with female predominance and frequent perimenopausal onset, indicating a potential pathogenic role for sex hormones. The goal…Abstract Number: 1580 • 2018 ACR/ARHP Annual Meeting
Persistent Serological Activity in Primary Sjögren’s Syndrome
Background/Purpose: To assess presence of persistent serological activity and its association with clinical outcomes in a cohort of patients with primary Sjögren’s syndrome (pSS). Methods:…Abstract Number: 1581 • 2018 ACR/ARHP Annual Meeting
Lack of Specificity in Testing for Murine Tissue Specific Autoantibodies for the Diagnosis of Sjogren’s Syndrome
Background/Purpose: A group of murine parotid tissue specific autoantibodies (TSAs) which includes anti-SP1 (salivary protein 1), anti-PSP (parotid secretory protein) and anti-CA6 (carbonic anhydrase) are…Abstract Number: 1582 • 2018 ACR/ARHP Annual Meeting
Clinical Correlations and Expression Pattern of the Autoimmunity Susceptibility Factor Diora-1 in Primary Sjögren’s Syndrome
Background/Purpose: Genome-wide association studies of multiple autoimmune diseases, including primary Sjögren’s syndrome (pSS), systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) have revealed an association…Abstract Number: 1583 • 2018 ACR/ARHP Annual Meeting
Low-Dose IL-2 Promotes the Proliferation of Peripheral Regulatory T Cells in Primary Sjogren’s Syndrome to Restore Its Balances with Pro-Inflammatory Lymphocytes
Background/Purpose: To investigate the effect of low-dose IL-2 on the balance of Treg with Teff and other pro-inflammatory lymphocytes in peripheral blood of pSS patients.Methods:…Abstract Number: 1584 • 2018 ACR/ARHP Annual Meeting
Evaluation of the Performance of the 2016 American College of Rheumatology-European League Against Rheumatism (Acr-Eular) Classification Criteria for Primary Sjogren`S Syndrome in Different Centers of Argentina
Background/Purpose: Primary Sjögren`s Syndrome (pSS) is a multisystemic, autoimmunity disease, characterized mainly by the hypofunction of the salivary and lacrimal glands, however the clinical spectrum…
ACR Meeting Abstracts