Abstracts Archive - Page 1282 of 2425 - ACR Meeting Abstracts

Abstract Number: 1147 • 2017 ACR/ARHP Annual Meeting
Macrophage Activation Syndrome or Acquired Hemophagocytic Lymphohistiocytosis in Adults: Demographics, Clinical Characteristics, and Survivorship in an American Academic Medical Center
Seema Malkana¹ and Irene Tan², ¹Internal Medicine, Temple University Hospital, Philadelphia, PA, ²Section of Rheumatology, Temple University Lewis Katz School of Medicine, Philadelphia, PA
Background/Purpose: Macrophage Activation Syndrome, also known as acquired Hemophagocytic Lymphohistiocytosis in adults, is an immune-mediated systemic inflammatory state. It is associated with multisystem organ failure…
Abstract Number: 1148 • 2017 ACR/ARHP Annual Meeting
Arthritis after Cancer Immunotherapy: Symptom Duration and Treatment Response
Melanie H. Smith¹ and Anne R. Bass^2,3, ¹Medicine, New York Presbyterian Hospital (Cornell), New York, NY, ²Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ³Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY
Background/Purpose: Checkpoint inhibitor immunotherapy has fundamentally changed the treatment for an actively expanding list of cancers, however its use is associated with immune related adverse…
Abstract Number: 1149 • 2017 ACR/ARHP Annual Meeting
Clinical Implications of Ultrasonography (US) in Monitoring Disease Activity of Relapsing Polychondritis (RP) and Comparative Investigation By US between Auricle of RP, Repeated Trauma and Healthy Subject
Eri Amano¹, Yoshinori Taniguchi², Satoshi Inotani¹, Hirofumi Nishikawa¹, Tatsuki Matsumoto³, Shuichi Nakayama⁴ and Yoshio Terada⁵, ¹Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School, Nankoku, Japan, ²Endocrinology, Metabolism,Nephrology and Rheumatology, Kochi University, Kochi, Japan, ³Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi University, Nankoku, Japan, ⁴Kochi Medical School, Nankoku, Japan, ⁵Kochi University, Nankoku, Japan
Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disorder and might often be refractory. Therefore, the discovery of more convenient imaging modality than contrast-CT,…
Abstract Number: 1150 • 2017 ACR/ARHP Annual Meeting
Ocular Involvement Is Exclusive with Genital Ulcer and Skin Lesion in the Early Phase of Behçet’s Disease: Nationwide Japanese Registration.
Nobuyuki Horita¹, Akiko Suwa², Mitsuhiro Takeno³, Takehito Ishido², Yohei Kirino⁴ and Nobuhisa Mizuki⁵, ¹National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ²Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ³Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ⁴Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ⁵Yokohama City University, Yokohama, Japan
Background/Purpose: Behçetfs disease (BD) is a chronic inflammatory syndrome with features of multi-organ involvement and presents with mucocutaneous and ocular symptoms. We have previously found…
Abstract Number: 1151 • 2017 ACR/ARHP Annual Meeting
Clinical Manifestations of BehçEt’s Disease Depending on Sex and Age: Nationwide Japanese Registration
Takehito Ishido¹, Nobuyuki Horita², Mitsuhiro Takeno³, Mizuho Ishido¹, Yohei Kirino⁴ and Nobuhisa Mizuki⁵, ¹Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ⁴Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ⁵Yokohama City University, Yokohama, Japan
Background/Purpose: Behçetfs disease (BD) has a broad spectrum of clinical phenotypes. Sex differences in BD presentation has been one of the major topics of BD…
Abstract Number: 1152 • 2017 ACR/ARHP Annual Meeting
Interleukin-37 As an Independent Disease Activity Marker of Adult-Onset Still’s Disease
Seoung Wan Nam¹, SuMan Kang², Hyoungyoung Kim³, Ga-Young Ahn⁴, Min Jung Kim³ and Dae-Hyun Yoo¹, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), ³Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), ⁴Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South)
Background/Purpose: Diagnosis and accurate measurement of disease activity in adult-onset Still¡¯s disease (AOSD) are still challenging due to its heterogeneous clinical manifestations and the lack…
Abstract Number: 1153 • 2017 ACR/ARHP Annual Meeting
Rheumatic Manifestations of Whim Syndrome
Ananta Subedi¹, Shubhasree Banerjee¹, Blas Betancourt¹, James D. Katz¹, Peter C. Grayson¹, Elena Cho², Daniel Velez², Philip M. Murphy² and David H. McDermott², ¹National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, ²National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD
Background/Purpose: WHIMS (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome) is a rare autosomal dominant primary immunodeficiency due to gain of function mutations of the CXC chemokine…
Abstract Number: 1154 • 2017 ACR/ARHP Annual Meeting
Use of Including Serum Ferritin and Heme Oxygenase 1 in the Yamaguchi’s Classification for Adult-Onset Still’s Disease: A Multicenter Retrospective Study
Yohei Kirino¹, Yasushi Kawaguchi², Yoshifumi Tada³, Hiroshi Tsukamoto⁴, Toshiyuki Ota⁵, Masahiro Iwamoto⁶, Hiroki Takahashi⁷, Kohei Nagasawa⁸, Syuji Takei⁹, Takahiko Horiuchi¹⁰, Hisae Ichida², Seiji Minota¹¹, Atsuhisa Ueda¹, Akihide Ohta¹² and Yoshiaki Ishigatsubo¹³, ¹Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ³Department of Internal Medicine, Division of Rheumatology, Saga University, Saga, Japan, ⁴Department of medicine and biosystemic science, Kyushu University Hospital, Fukuoka, Japan, ⁵Department of Rheumatology, Iizuka Hospital, Iizuka, Japan, ⁶Deivision of Rheumatology and Clinical Immunology, Jichi Medical University, Shimotsuke, Japan, ⁷Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan, ⁸Rheumatic Disease Center, Sawara Hospital, Sawara, Japan, ⁹Pediatrics of Developmental Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, ¹⁰Department of Internal Medicine, Kyushu University Beppu Hospital, Beppu, Japan, ¹¹Department of Internal Medicine, Division of Rheumatology/Clinical Immunology, Jichi Medical University, Shimotsuke, Japan, ¹²Saga University School of Medicine, Saga, Japan, ¹³Yokohama City University, Yokohama, Japan
Background/Purpose: Yamaguchi’s criteria for classification of adult-onset Still’s disease (AOSD) has been widely applied in clinic despite it was established decades ago. However, hyperferritinemia, which…
Abstract Number: 1155 • 2017 ACR/ARHP Annual Meeting
Impact of Adalimumab on Immunosuppressant Use in Patients with Active and Inactive Non-Infectious Intermediate, Posterior, or Pan-Uveitis in the Ongoing Open Label Study: Visual-III
Sergio Schwartzman¹, Irene Van der Horst-Bruinsma², Alfredo Adan³, Hiroshi Goto⁴, Koju Kamoi⁵, Martina Kron⁶, Alexandra P. Song⁷, Kevin Douglas⁷, Sophia Pathai⁸ and C. Stephen Foster⁹, ¹Hospital for Special Surgery, New York, NY, ²Department of Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ³Hospital Clinic. Barcelona. Spain, Barcelona, Spain, ⁴Tokyo Medical University, Tokyo, Japan, ⁵Tokyo Medical and Dental University, Tokyo, Japan, ⁶AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany, ⁷AbbVie Inc., North Chicago, IL, ⁸AbbVie Ltd, Maidenhead, United Kingdom, ⁹Massachusetts Eye Research and Surgery foundation and Harvard Medical School, Boston, MA
Background/Purpose: The morbidity associated with the use of immunosuppressants is well described in patients (pts) with autoimmune ophthalmic disease and presents a challenge to treating…
Abstract Number: 1156 • 2017 ACR/ARHP Annual Meeting
Rheumatic Immune Related Adverse Events from Checkpoint Inhibitor Therapy for Cancer: Long-Term Follow up Data
Cassandra Calabrese¹, Elizabeth Kirchner¹, Apostolos Kontzias¹, Laura Wood², Brian Rini², Vamsidhar Velcheti² and Leonard H. Calabrese¹, ¹Rheumatic & Immunologic Disease, Cleveland Clinic Foundation, Cleveland, OH, ²Hematology and Oncology, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: The new and emerging field of immune related adverse events (irAEs) from cancer immunotherapies presents many unanswered questions. The spectrum of irAEs is broad…
Abstract Number: 1157 • 2017 ACR/ARHP Annual Meeting
Hypocomplementemia Is Closely Related to IgG Subclasses Other Than IgG4 in IgG4-Related Disease
Ichiro Mizushima¹, Kazunori Yamada², Motohisa Yamamoto³, Takako Saeki⁴, Shoko Matsui⁵, Satoshi Hara⁶, Hiroki Takahashi⁷, Hideki Nomura⁸, Shigeyuki Kawa⁹ and Mitsuhiro Kawano⁶, ¹Kanazawa University Hospital, Kanazawa, Japan, ²Department of Advanced Research in Community Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, ³First Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, ⁴Department of Internal Medicine, Nagaoka Red Cross Hospital, Nagaoka, Japan, ⁵Health Administration Center, University of Toyama, Toyama, Japan, ⁶Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan, ⁷Department of Gastroenterology, Rheumatology and Clinical Immunology, Sapporo Medical University School of Medicine, Sapporo, Japan, ⁸Department of General Medicine, Kanazawa University Hospital, Kanazawa, Japan, ⁹Center for Health, Safety and Environmental Management, Shinshu University, Matsumoto, Japan
Background/Purpose: Hypocomplementemia frequently occurs in IgG4-related disease (IgG4-RD), especially IgG4-related kidney disease (IgG4-RKD). This study aimed to investigate the clinical features of IgG4-RD patients (pts)…
Abstract Number: 1158 • 2017 ACR/ARHP Annual Meeting
Treatment of Non-Infectious Uveitis: A Comparative Long-Term Study between Biologic Therapy with Adalimumab and Two Conventional Disease-Modifying Antirheumatic Drugs
Esteban Rubio Romero¹, Roberto Aguilar Galán², Raúl Menor Almagro¹, Alejandro Muñoz¹ and Juan Povedano¹, ¹Rheumatology, Hospital Universitario Virgen del Rocío, Sevilla, Spain, ²Ophthalmology, Hospital Universitario Virgen del Rocío, Sevilla, Spain
Background/Purpose: Uveitis are inflammatory processes of the vascular layer of the eye, the uvea, which is divided into iris (anterior uvea), ciliary body (intermediate) and…
Abstract Number: 1159 • 2017 ACR/ARHP Annual Meeting
National Recommendations on the Use of Immunomodulatory Drugs in Patients with NON-Infectious NON-Malignant Anterior Uveitis
Gerard Espinosa¹, Santiago Muñoz², Jose M Ruiz de Morales³, Jose M Herreras⁴ and Miguel Cordero-Coma⁵, ¹Autoimmune Diseases Department. Hospital Clínic de Barcelona, Barcelona, Spain, ²Rheumatology, Hospital Infanta Sofia, Madrid, Spain, ³Complejo Asistencial Universitario de León, León, Spain, ⁴Ophthalmology, Hospital Universitario, IOBA, Valladolid, Spain, ⁵Ophthalmology, Hospital de León. Spain, León, Spain
Background/Purpose: Anterior uveitis (AU) is the most common pattern of uveitis, that migh lead to important ocular complications including blindness. Immunomodulatory drugs have been used…
Abstract Number: 1160 • 2017 ACR/ARHP Annual Meeting
Increased Incidence of Upper and Lower Gastrointestinal Events in Patients with Sarcoidosis: A Population-Based Cohort Study
Patompong Ungprasert¹, Cynthia S. Crowson² and Eric L. Matteson³, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN
Increased Incidence of Upper and Lower Gastrointestinal Events in Patients with Sarcoidosis: A Population-Based Cohort StudyBackground/Purpose: An increased incidence of gastrointestinal (GI) events has…
Abstract Number: 1161 • 2017 ACR/ARHP Annual Meeting
Clinical Characteristics of Ocular Sarcoidosis: A Population Based Study 1976-2013
Patompong Ungprasert¹, Andrea Tooley², Cynthia S. Crowson³, Eric L. Matteson⁴ and Wendy M. Smith⁵, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Opthalmology, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁴Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵Department of Ophthalmology, Mayo Clinic, Rochester, MN
Clinical Characteristics of Ocular Sarcoidosis: A Population Based Study 1976-2013Background/Purpose: To characterize the epidemiology and clinical characteristics of ocular involvement in patients with systemic sarcoidosis.Methods:…

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