Abstract Number: 1072 • 2017 ACR/ARHP Annual Meeting
Mutated Peptidylarginine Deiminase from Porphyromonas Gingivalis Is a Target in Rheumatoid Arthritis and Citrullinates Major RA-Autoantigens
Background/Purpose: Previous reports showed that peptidylarginine deiminase (PPAD) form Porphyromonas gingivalis (P.g.) is not able to citrullinate proteins internally. Mutated PPAD (mPPAD) from P.g. involved…Abstract Number: 1073 • 2017 ACR/ARHP Annual Meeting
Aberrant Cell Signaling in Peripheral Blood Mononuclear Cells upon Interferon Alpha Stimulation in Patients with Primary Sjögren’s Syndrome Associates with Type I Interferon Signature
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a complex heterogeneous systemic autoimmune disease. Biomarkers for patient stratification are scarce. Several single nucleotide polymorphisms within type I…Abstract Number: 1074 • 2017 ACR/ARHP Annual Meeting
High Cholesterol Levels By ApoE Defenciency Reduce Bone Destruction in Murine Antigen-Induced Arthritis Via Inhibition of Osteoclastogenesis
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by immune complex- deposition in the synovium, leading to increased bone destruction. In RA, joint…Abstract Number: 1075 • 2017 ACR/ARHP Annual Meeting
Higher Frequencies of Lymphocytes Expressing the Natural Killer Group 2D Receptor and Cytotoxic Potential of NK Cells in Patients with Behcet Disease
Background/Purpose: Behçhet disease (BD) is a rare, systemic, inflammatory disorder with multiorgan damage and various clinical manifestations such as oral ulcers, genital ulcers and uveitis.…Abstract Number: 1076 • 2017 ACR/ARHP Annual Meeting
TGF-β1 Induces AXL in Murine and Human Synovium and Protects Ankle Joints, but Not Knee Joints, during Murine Inflammatory Arthritis
Background/Purpose: Rheumatoid arthritis (RA) manifests in a symmetrical fashion in anatomically distinct synovial joints. The innate immune system, which plays a crucial role in the…Abstract Number: 1077 • 2017 ACR/ARHP Annual Meeting
The Lectin Pathway of the Complement System Is Activated in Patients with Systemic Lupus Erythematosus
Background/Purpose: The pathogenesis of Systemic Lupus Erythematosus (SLE) involves complement activation. It is well established that activation of complement through the classical pathway (CP) and…Abstract Number: 1078 • 2017 ACR/ARHP Annual Meeting
Initial Combination Therapy Versus Step-up Therapy Is More Effective and Less Costly As a Treat to Target Strategy for RA: A Markov Model Based upon the Dutch Rheumatoid Arthritis Monitoring Registry Cohorts
Background/Purpose: Adjusting medication of patients with rheumatoid arthritis (RA) until predefined disease activity targets are met, i.e. Treat to Target (T2T), is the currently recommended…Abstract Number: 1079 • 2017 ACR/ARHP Annual Meeting
Treat to Target Adherence Measurement Tool Performance in Rheumatoid Arthritis
Background/Purpose: The purpose of the T2T approach in RA is to achieve remission or LDA according to results from objective activity measurements. This strategy has…Abstract Number: 1080 • 2017 ACR/ARHP Annual Meeting
Electronic Patient Reported Outcomes Increase Pediatric Rheumatology Clinic Operations Efficiency While Increasing Patient and Caregiver Satisfaction
Electronic Patient Reported Outcomes Increase Pediatric Rheumatology Clinic Operations Efficiency While Increasing Patient and Caregiver SatisfactionBackground/Purpose: Patient reported outcomes (PROs) are powerful tools that facilitate…Abstract Number: 1081 • 2017 ACR/ARHP Annual Meeting
Improving Patient-Reported Outcomes Collection and Documentation for Patients with Rheumatoid Arthritis at Multilingual, Safety Net Hospital Rheumatology Clinic
Background/Purpose: The Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function-10a (PF10a) survey is a reliable and valid measure of function in patients with rheumatoid arthritis…Abstract Number: 1082 • 2017 ACR/ARHP Annual Meeting
Responsiveness and Minimally Clinically Important Differences of Promis Measures in Rheumatoid Arthritis
Responsiveness and Minimally Clinically Important Differences of PROMIS Measures in Rheumatoid ArthritisBackground/Purpose: The ability to detect meaningful change in clinical status (responsiveness) is an important…Abstract Number: 1083 • 2017 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Patients Achieved Better Quality of Life Than Systemic Lupus Erythematosus Patients at Sustained Remission: The Impact of Disease Diagnosis on Health-Related Quality of Life Outcomes
Background/Purpose: Patients with Systemic Lupus Erythematous (SLE) and Rheumatoid Arthritis (RA) had profound negative effects on their health-related quality of life (HRQoL) that can be…Abstract Number: 1084 • 2017 ACR/ARHP Annual Meeting
Emdhaq: (electronic multidimensional health assessment questionnaire) to Record and Document eRAPID3 (electronic routine assessment of patient index data3) and eFAST3 (electronic fibromyalgia assessment screening tool3) in Routine Rheumatology Care
Background/Purpose: RAPID3 (routine assessment of patient index data) on a multi-dimensional health assessment questionnaire (MDHAQ) distinguishes active from control treatments in RA clinical trials as…Abstract Number: 1085 • 2017 ACR/ARHP Annual Meeting
Application of Lupus Nephritis Quality Measures to Understand Gaps in Care for SLE
Background/Purpose: In 2012, the ACR released guidelines for monitoring and treatment of lupus nephritis (LN), but studies have yet to evaluate adherence to these recommendations.…Abstract Number: 1086 • 2017 ACR/ARHP Annual Meeting
Screening and Intervention of Depression in Rheumatoid Arthritis and Systemic Lupus Erythematosus
Background/Purpose: Depression is common and associated with worse outcomes among patients with RA and SLE. Our study assessed depression using Patient Help Questionnaire (PHQ-9) and…