Abstracts Archive - Page 1262 of 2607 - ACR Meeting Abstracts

Abstract Number: 1135 • 2018 ACR/ARHP Annual Meeting
Genome-Wide Meta-Analysis Identified Two Novel Variants Associated with Hallux Valgus
Liubov Arbeeva¹, Braxton Mitchell², Rebecca D. Jackson³, Michelle S. Yau⁴, Kathleen Ryan⁵, Yvonne M. Golightly⁶, Marian T. Hannan⁷, Amanda Nelson⁸, Joanne M. Jordan⁹ and Marc C. Hochberg², ¹TARC, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²School of Medicine, University of Maryland, Baltimore, MD, ³Ohio State University, Columbus, OH, ⁴Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ⁵University of Maryland, Baltimore, MD, ⁶Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁷Institute for Aging Research, Hebrew SeniorLife & Harvard Medical School, Boston, MA, ⁸UNC School of Medicine, Chapel Hill, NC, ⁹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Hallux valgus (HV) is a common foot disorder that is highly heritable. A genome-wide association study (GWAS) conducted in 4,409 Caucasians from the Framingham…
Abstract Number: 1136 • 2018 ACR/ARHP Annual Meeting
Association of Mitochondrial DNA Haplotypes with Symptomatic Hand and Thumb Based Osteoarthritis and Hand OA Progression
Charles Eaton¹, Mary Roberts², Jeffrey B. Driban³, Ida Kristin Haugen⁴, Lena Franziska Schaefer⁵, Bing Lu⁶, Rebecca D. Jackson⁷, Marc C. Hochberg⁸, C. Kent Kwoh⁹, Francisco J Blanco¹⁰ and Timothy E. McAlindon¹¹, ¹Family Medicine and Epidemiology, Warren Alpert Medical School, School of Public Health, Brown University, Providence, RI, ²Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, ³Rheumatology, Tufts Medical Center, BOSTON, MA, ⁴Diakonhjemmet Hospital, Oslo, Norway, ⁵Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁶Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, ⁷Ohio State University, Columbus, OH, ⁸School of Medicine, University of Maryland, Baltimore, MD, ⁹Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, ¹⁰Rheumatology Division, ProteoRed, PRB2-ISCIII. INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, ¹¹Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Hand osteoarthritis (OA) can be a painful, disabling condition, with an increased prevalence in women, the elderly, and has a strong genetic component (hereditability…
Abstract Number: 1137 • 2018 ACR/ARHP Annual Meeting
Prediction Models for Poor Function Outcomes over 10 Years in Persons at High Risk for Knee Osteoarthritis
Leena Sharma¹, Orit Almagor¹, Alison H. Chang¹, C. Kent Kwoh², Michael C. Nevitt³, Marc C. Hochberg⁴, Rebecca D. Jackson⁵, Charles B. Eaton⁶, Jane A. Cauley⁷, Julie Szymaszek⁸ and Joan S. Chmiel¹, ¹Northwestern University, Chicago, IL, ²University of Arizona, Tucson, AZ, ³UCSF, San Francisco, CA, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Ohio State University, Columbus, OH, ⁶Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, ⁷University of Pittsburgh, PIttsburgh, PA, ⁸Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Among persons at high risk for knee osteoarthritis (OA), identifying those who will have function decline is important; instituting prevention strategies in all…
Abstract Number: 1138 • 2018 ACR/ARHP Annual Meeting
Public Health Impact of Physical Inactivity in the Knee OA Population in the US
Elena Losina¹, Genevieve S. Silva², Karen C. Smith², Jamie E. Collins³, David J. Hunter⁴, Swastina Shrestha², Stephen P. Messier⁵, Edward H. Yelin⁶, Lisa Gale Suter⁷, A. David Paltiel⁸ and Jeffrey N. Katz⁹, ¹Orthopedics, Brigham and Women's Hospital, BU School of Public Health and Harvard Medical School, Boston, MA, ²Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ³Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁵Department of Health and Exerc, Wake Forest University, Winston-Salem, NC, ⁶Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ⁷Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, ⁸Yale University, New Haven, CT, ⁹Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: The benefits of physical activity (PA) in persons with OA are well-documented: PA reduces OA pain, improves mental health, and reduces the risk of…
Abstract Number: 1139 • 2018 ACR/ARHP Annual Meeting
Can Body Composition Explain the Sex Disparity in Risk of Osteoarthritis?
Shanshan Li¹, Tuhina Neogi², Devyani Misra³, Ann Schwartz⁴, Michael C. Nevitt⁵, Cora E. Lewis⁶, James Torner⁷ and David T. Felson², ¹Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Cambridge, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³School of Medicine, Boston University School of Medicine, Boston, MA, ⁴University of California San Francisco, San Francisco, CA, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶University of Alabama Birmingham, Birmingham, AL, ⁷University of Iowa, Iowa City, IA
Background/Purpose: Obesity is a major risk factor for knee osteoarthritis (OA), but the mechanisms by which obesity confers OA risk remains unclear. There is a…
Abstract Number: 1140 • 2018 ACR/ARHP Annual Meeting
Cause-Specific Mortality in Knee, Hip and Hand Osteoarthritis
Aleksandra Turkiewicz, Aliasghar Kiadaliri and Martin Englund, Clinical Sciences Lund, Clinical Epidemiology Unit, Lund University, Lund, Sweden
Background/Purpose: All-cause mortality in osteoarthritis (OA) is reported to be increased. However, the knowledge about cause-specific mortality in OA is still very limited. Thus, our…
Abstract Number: 1141 • 2018 ACR/ARHP Annual Meeting
Trajectories of Extensive Sitting and Associated Predictors in Persons at High Risk for Knee Osteoarthritis
Julia (Jungwha) Lee¹, Alison H. Chang², Orit Almagor², Joan S. Chmiel³, Karen W. Hayes², C. Kent Kwoh⁴ and Leena Sharma⁵, ¹Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, ⁵Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Too much sitting has been recognized as a major public health issue. However, it is unknown if distinctive patterns of extensive sitting over time…
Abstract Number: 1142 • 2018 ACR/ARHP Annual Meeting
Trend of Lymphoma Incidence in US Veterans with Rheumatoid Arthritis Vs Osteoarthritis: 2002-2017
Namrata Singh¹, Yubo Gao², Brice Beck³, Bryant R. England⁴, Grant W. Cannon⁵, Ted R. Mikuls⁶, Jeffrey R. Curtis⁷, Brian Link⁸, Charles Lynch⁹, Elizabeth Field¹⁰ and Mary Vaughan-Sarrazin², ¹Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, ²University of Iowa Hospitals and Clinics, Iowa City, IA, ³Internal Medicine, Iowa City VA Medical Center, Iowa City, IA, ⁴Rheumatology, VA Nebraska-Western Iowa Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁵Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶Internal Medicine, Division of Rheumatology, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ⁷University of Alabama, Birmingham, AL, ⁸Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, ⁹Epidemiology, University of Iowa, Iowa City, IA, ¹⁰Iowa City VA, Iowa City, IA
Background/Purpose: Past epidemiologic studies have consistently demonstrated a link between Rheumatoid Arthritis (RA) and lymphomas and have posited that high systemic inflammatory activity is a…
Abstract Number: 1143 • 2018 ACR/ARHP Annual Meeting
Periodontal Disease Is Associated with an Increased Risk of Ankylosing Spondylitis: A Systematic Review and Meta-Analysis
Patompong Ungprasert¹, Karn Wijarnpreecha² and Wisit Cheungpasitporn³, ¹Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ²Internal medicine, Bassett medical center, cooperstown, NY, ³Medicine, University of Mississippi Medical center, Jackson, MS
Periodontal Disease is Associated with an Increased Risk of Ankylosing Spondylitis: A Systematic Review and Meta-analysisAbstractBackground/Purpose: The association between periodontal disease and rheumatoid arthritis is…
Abstract Number: 1144 • 2018 ACR/ARHP Annual Meeting
Risk of Osteoporotic Fractures in Patients with Rheumatoid Arthritis and End Stage Renal Disease. Findings from the Usrds Database
Renee Peterkin-McCalman, Jennifer Waller, Brian Le, Alyce Oliver, Evan Manning, Stanley Nahman and Laura Carbone, Medical College of Georgia at Augusta University, Augusta, GA
Background/Purpose: Rheumatoid arthritis (RA) and End Stage Renal Disease (ESRD) are independent risk factors for osteoporotic fractures. Approximately one percent of persons with ESRD have…
Abstract Number: 1145 • 2018 ACR/ARHP Annual Meeting
Association of Niacin Intake with Osteoporosis. the Cardiovascular Health Study
Brian Le¹, Petra Bůžková², Howard Fink³, John Robbins⁴, Mattie Raiford¹, Carlos Isales¹, James Shikany⁵, Steven Coughlin¹ and Laura Carbone¹, ¹Medical College of Georgia at Augusta University, Augusta, GA, ²Washington University, Seattle, WA, ³Minneapolis VA Health Care System, Minneapolis, MN, ⁴University of California-Davis, Sacramento, CA, ⁵University of Alabama, Birmingham, AL
Background/Purpose: Interest in niacin has increased in the setting of reports suggesting that niacin plays a role in diseases of aging, including Parkinson’s disease and…
Abstract Number: 1146 • 2018 ACR/ARHP Annual Meeting
The Association of Raas Inhibitor Use with Osteoporosis. Findings from the Women’s Health Initiative
Laura Carbone¹, Sowmya Vassan², Ross Prentice², Greg Harshfield¹, Bernhard Haring³, Jane A. Cauley⁴ and Karen Johnson⁵, ¹Medical College of Georgia at Augusta University, Augusta, GA, ²Fred Hutchinson Cancer Research Center, Seattle, WA, ³University of Wurzburg, Bavaria, Germany, ⁴University of Pittsburgh, PIttsburgh, PA, ⁵University of TN Health Science Center, Memphis, TN
Background/Purpose: Experimental studies have implicated a role for the Renin Angiotensin Aldosterone System (RAAS) in osteoporosis. However, the relationship of pharmacological inhibition of the RAAS…
Abstract Number: 1147 • 2018 ACR/ARHP Annual Meeting
Golimumab Improves Work Productivity and Activity Impairment in Patients with Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA): 1-Year Results from a Non- Interventional Trial in Germany
Klaus Krüger¹, Sven Remstedt², Astrid Thiele³ and Ines Klaudius⁴, ¹Medical Centre of Rheumatology, Munich, Germany, ²Rheuma Praxis Berlin, Berlin, Germany, ³Krankenhaus St. Josef Wuppertal, Wuppertal, Germany, ⁴MSD Sharp & Dohme GmbH, Haar, Germany
Background/Purpose: Non-interventional studies (NIS) are essential instruments in pharmaceutical research not only for pharmaceutical companies but also for regulatory authorities or reimbursement bodies in Germany.…
Abstract Number: 1148 • 2018 ACR/ARHP Annual Meeting
The Effects of Physical Activity on Bone Density of High School Girls: A Prospective Study
Ria Desai¹, Brian Carpenter¹, Matthew Kennedy¹, Milind Desai², Lisa Damour¹ and Chad Deal^3,4, ¹Laurel School, Shaker Heights, OH, ²Cleveland Clinic, Cleveland, OH, ³Orthopedic and Rheumatology Institute, Cleveland Clinic Foundation, Cleaveland, OH, ⁴Cleveland Clinic, Shaker Heights, OH
Background/Purpose: More than 50% of peak bone mass (PBM) is gained during adolescence and high impact exercise has been shown to impact bone accrual. We…
Abstract Number: 1149 • 2018 ACR/ARHP Annual Meeting
Contemporary Prevalence of Gout and Hyperuricemia in the United States (National Health and Nutrition Examination Survey [NHANES] 2015-2016) and Decadal Trends (NHANES 2007-2016)
Michael Chen-Xu¹, Chio Yokose², Michael Pillinger³ and Hyon K. Choi², ¹General Medicine, Wairarapa District Health Board, Masterton, New Zealand, ²Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ³Medicine/Rheumatology, NYU School of Medicine, New York, NY
Background/Purpose: The prevalences of gout and hyperuricemia from the National Health and Nutrition Examination Survey (NHANES) 2007-2008 were 3.9% (8.3 million) and 21.4% (43.3 million…

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