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  • Abstract Number: 940 • 2018 ACR/ARHP Annual Meeting

    Inactivated Influenza Vaccine Prevents Respiratory Infections and Improves All-Cause and Cause-Specific Mortality in Immunosuppressed People with Autoimmune Rheumatic Diseases: Propensity Score Adjusted Cohort Study Using Data from Clinical Practice Research Datalink

    Georgina Nakafero1, Matthew Grainge2, Puja Myles2, Christian Mallen3, Weiya Zhang1, Michael Doherty4, Jonathan Nguyen-van-tam2 and Abhishek Abhishek1, 1Academic Rheumatology, The University of Nottingham, Nottingham, United Kingdom, 2Epidemiology and Public Health, The University of Nottingham, Nottingham, United Kingdom, 3Research Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom, 4The University of Nottingham, Nottingham, United Kingdom

    Background/Purpose: To assess the effectiveness of inactivated influenza vaccine (IIV) in preventing influenza like illness (ILI), lower respiratory tract infection (LRTI), pneumonia, chronic obstructive pulmonary…
  • Abstract Number: 941 • 2018 ACR/ARHP Annual Meeting

    Causal Inference Methods for the Effect of Rheumatoid Arthritis on Mortality Independent of Lifestyle and Clinical Factors before and after RA Diagnosis

    Jeffrey A. Sparks1, Kazuki Yoshida1,2, Tzu-Chieh Lin3, Carlos Camargo4, Benjamin Raby5, Hyon K. Choi6, Medha Barbhaiya7, Sara K. Tedeschi1, Bing Lu8, Karen Costenbader1 and Elizabeth Karlson1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Harvard T.H. Chan School of Public Health, Boston, MA, 3Amgen, Thousand Oaks, CA, 4Emergency Medicine, Massachusetts General Hospital, Boston, MA, 5Pulmonary, Brigham and Women's Hospital, Boston, MA, 6Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 7Rheumatology, Hospital for Special Surgery, New York, NY, 8Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: RA is associated with increased total, cardiovascular, and respiratory mortality compared to the general population. This excess RA mortality may be mediated through lifestyle,…
  • Abstract Number: 942 • 2018 ACR/ARHP Annual Meeting

    Risk of Serious Infections in Tocilizumab Versus TNF Inhibitor Initiators in Patients with RA: A Multi-Database Cohort Study

    Ajinkya Pawar1, Rishi J. Desai2, Daniel Solomon1, Sara Gale3, Min Bao4, Khaled Sarsour3, Sebastian Schneeweiss1 and Seoyoung C. Kim1, 1Brigham and Women's Hospital, Boston, MA, 2Division of Pharmacoepidemiology and Pharmacoeconimics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Genentech, South San Francisco, CA, 4Roche Innovation Center, New York, NY

    Background/Purpose: While biologics are known to be associated with risk of serious infections, data on head-to-head comparison of different biologic drugs for the risk of…
  • Abstract Number: 943 • 2018 ACR/ARHP Annual Meeting

    Risk of Prostate Cancer in US Veterans with Rheumatoid Arthritis

    Kaitlyn Brittan1, Punyasha Roul2, Joshua Baker3, Brian Sauer4, Namrata Singh5, Harlan Sayles2, Grant W. Cannon6, Ted R. Mikuls7 and Bryant R. England8, 1University of Nebraska Medical Center & VA Nebraska-Western IA Health Care System, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3Philadelphia VA Medical Center and University of Pennsylvania, Philadelphia, PA, 4Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 5Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, 6Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 7VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 8Rheumatology, VA Nebraska-Western Iowa Health Care System & University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at a small, but significantly increased risk of cancer compared with the general population. This risk varies by…
  • Abstract Number: 944 • 2018 ACR/ARHP Annual Meeting

    Gout: A Potential Risk Factor for Uveitis in the Older Adults?

    Jasvinder A. Singh and John Cleveland, Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Elevated intraocular levels of these pro-inflammatory cytokines and systemic levels of C-reactive protein are seen in uveitis, which leads to 30,000 new cases of…
  • Abstract Number: 945 • 2018 ACR/ARHP Annual Meeting

    Pain, Functional Limitations and Physical Activity Participation Trajectories in Patients with Symptomatic Knee and Hip Osteoarthritis: A Multi-Trajectory Analysis

    Maud Wieczorek1, Christine Rotonda1, Francis Guillemin1,2 and Anne-Christine Rat1,3, 1Université de Lorraine, EA4360, APEMAC, Nancy, France, 2Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, 3Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France

    Background/Purpose: The aims of this study were to identify homogeneous subgroups of knee and/or hip osteoarthritis (OA) patients with distinct trajectories of the combination of…
  • Abstract Number: 946 • 2018 ACR/ARHP Annual Meeting

    Short-Term Safety of Fractional-Dose Yellow Fever Vaccination in Autoimmune Rheumatic Diseases and Kinetics of White Blood Cells

    Adriana C Tonacio1, Tatiana N Pedrosa2, Julio CR Ferreira Filho2, Marilia M Sampaio-Barros2, Ricardo Fuller2, Michelle Lopes2, Eduardo Ferreira Borba2, Sandra G Pasoto2, Emilly Neves2, Clovis A Silva3, Rosa M R Pereira4, Percival Sampaio-Barros5, Danieli Andrade2, Ana CM Ribeiro2, Julio CB Moraes6, Samuel K Shinjo7, Renata Miossi8, Hermes Higashino9, Silvia Costa9, Alberto Duarte10, Elaine P Leon2, Marta Lopes9, Nadia E Aikawa2 and Eloisa Bonfa11, 1Infectology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 3Pediatric Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 4Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR., São Paulo, Brazil, 6Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 8Rheumatology, Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 9Infectology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 10Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 11Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Brazil faced a new yellow fever (YFV) outbreak that reached the state of Sao Paulo in December 2016. The fractional dose was used in…
  • Abstract Number: 947 • 2018 ACR/ARHP Annual Meeting

    Clinical Characteristics and Outcome after Treatment of a National Cohort of PCR-Positive Lyme Arthritis

    Marc Scherlinger1,2, Antoine Grillon3, Jean Sibilia4, Benoit Jaulhac3 and Laurent Arnaud4,5, 1Department of Rheumatology, Bordeaux University Hospital, Bordeaux, France, 2Rheumatology, UMR CNRS 5164 - Immunoconcept, France, Bordeaux, France, 3Centre national de référence Borrelia, CHU de Strasbourg, Strasbourg, France, 4Université de Strasbourg, Strasbourg, France, 5Service de rhumatologie, CHU de Strasbourg, Strasbourg, France

    Background/Purpose: Lyme arthritis (LA) is a disseminated Borrelia infection whom prevalence is lower in Europe than in the USA, probably because of difference in Borrelia…
  • Abstract Number: 948 • 2018 ACR/ARHP Annual Meeting

    Effects of Antiretroviral Therapy with Tenofovir and Other Antiretroviral Drugs on the Inflammatory State and Bone Remodeling on Newly Diagnosed HIV-Patients at Basal and 3 Months after Starting Treatment

    Aranzazu Mediero1, Francisco Miguel Conesa-Buendia2, Patricia Llamas3, Patricia Atencio4, Ramon Perez-Tanoira4, Alfonso Cabello5, Laura Prieto-Perez4, Beatriz Alvarez4, Manuel Fernandez-Guerrero4, Raquel Largo6, Gabriel Herrero-Beaumont6 and Miguel Gorgolas7, 1Joint and Bone Research Unit, IIS-Fundación Jiménez Díaz UAM, Madrid, Spain, 2Bone and Joint Research Unit, IIS-Fundacion Jimenez Diaz- UAM, Madrid, Spain, 3Bone and Joint Research Unit, IIS-Fundacion Jimenez Díaz-UAM, Madrid, Spain, 4Internal Medicine Department, IIS-Fundacion Jimenez Diaz, MADRID, Spain, 5Internal MEdicine Department, IIS-Fundacion Jimenez Diaz-UAM, Madrid, Spain, 6Bone and Joint Research Unit, Fundación Jiménez Díaz University Hospital & Health Research Institute, Madrid, Spain, 7Internal Medicine Department, IIS-Fundacion Jimenez Diaz-UAM, Madrid, Spain

    Background/Purpose: Bone alterations have been observed in the course of HIV infection, with a notable decreases in bone mineral density (BMD) and fractures due to…
  • Abstract Number: 949 • 2018 ACR/ARHP Annual Meeting

    Long-Term Rheumatic and Musculoskeletal Disorders Associated to Ebola Virus Infection

    Yves-Marie PERS1,2, Anne DUBOIS3, Alimou BARRY4, Mariama SALL4, Mamadou SALIOU SOW5, Bernard TAVERNE6, Laura MARCH6, Jean-François ETARD6, Moumié BARRY7, Abdoulaye TOURE8 and Eric DELAPORTE6, 1Clinical Immunology and Osteoarticular Diseases Therapeutic Unit, Lapeyronie University Hospital Montpellier, MONTPELLIER, France, 2INSERM U1183, IRMB, INSERM U1183, Montpellier, France, 3Clinical immunology and osteoarticular diseases Therapeutic Unit, Lapeyronie University Hospital, Montpellier, France., Montpellier, France, 4Infectious disease, Donka University National Hospital, Conakry, Guinea, 5Infectious Disease, Donka University National Hospital, CONAKRY, Guinea, 6IRD UMI 233 INSERM U1175, University Montpellier, MONTPELLIER, France, 7Hôpital National Donka, CHU de Conakry, Service des Maladies Infectieuses et Tropicales, Conakry, Guinea, 8Department of Pharmacy, Conakry University, CONAKRY, Guinea

    Background/Purpose: Between December 2013 and April 2016, the largest epidemic of Ebola virus disease (EVD) to date generated more than 28,000 cases and more than…
  • Abstract Number: 950 • 2018 ACR/ARHP Annual Meeting

    Ultrasonographic Examinations Show Highly Prevalent Abnormalities of Hamstring Tendons in Lyme Arthritis Patients

    Sheila Arvikar1, Minna Kohler1, Amar Oza2 and Allen C. Steere1, 1Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Allergy, Immunology, and Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Lyme arthritis (LA), the most common late manifestation of Lyme disease, usually occurs months to up to 2 years after the initial infection. Joint…
  • Abstract Number: 951 • 2018 ACR/ARHP Annual Meeting

    IFN-Gamma Production in Lyme Arthritis Synovial Tissue Promotes Differentiation of Fibroblast-like Synoviocytes into Inflammatory Effector Cells

    Robert Lochhead1, David Ordonez-Del Valle1, Sheila Arvikar2, Allen C. Steere2 and Klemen Strle3, 1Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, BOSTON, MA, 2Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Department of Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, BOSTON, MA

    Background/Purpose: Lyme arthritis (LA), a late-disease manifestation of Borrelia burgdorferi infection, usually responds to antibiotic therapy. However, some patients may develop a proliferative synovitis lasting…
  • Abstract Number: 952 • 2018 ACR/ARHP Annual Meeting

    Effusion-Synovitis and Infrapatellar Fat Pad Edema Differentiate Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative

    Julie Davis1, Robert J. Ward2, James MacKay3, Bing Lu4, Lori Lyn Price5,6, Timothy E. McAlindon7, Charles B. Eaton8, Mary Barbe9, Grace H. Lo10, Matthew Harkey1 and Jeffrey B. Driban11, 1Rheumatology, Tufts Medical Center, Boston, MA, 2Radiology, Tufts Medical Center, Boston, MA, 3Radiology, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom, 4Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 5Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, 6Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 7Division of Rheumatology, Tufts Medical Center, Boston, MA, 8Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, 9Temple University School of Medicine, Philadelphia, PA, 10Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, 11Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Accelerated knee osteoarthritis (AKOA) is a unique endotype of knee osteoarthritis (KOA) that is characterized by a sudden onset of advance-stage disease and greater…
  • Abstract Number: 953 • 2018 ACR/ARHP Annual Meeting

    Evaluating MRI-Detected Knee Inflammation Prior to Total Knee Replacement As a Predictive Biomarker of Clinically Important Pain Reduction Two Years Later

    Manjinder Kaur1, Lili Zhou2, Erin L. Ashbeck2, Ernest Vina3, Frank Roemer4, Ali Guermazi5, David J. Hunter6 and C. Kent Kwoh1,2, 1Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, 2University of Arizona Arthritis Center, Tucson, AZ, 3University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, 4Department of Radiology, Boston University School of Medicine, Boston, MA, USA, Boston, MA, 5Boston University School of Medicine, Boston, MA, 6University of Sydney, Sydney, Australia

    Background/Purpose: Some patients do not experience clinical improvement after total knee replacement (TKR). Presence of structural abnormalities on MRI before surgery may inform pain prognosis…
  • Abstract Number: 954 • 2018 ACR/ARHP Annual Meeting

    A New Way to Think about Composite Magnetic Resonance Imaging Scores to Measure Osteoarthritis Severity and Progression

    Lori Lyn Price1,2, Jeffrey B. Driban3, Grace H. Lo4, Ming Zhang5, Michael P. LaValley6 and Timothy E. McAlindon7, 1Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 2Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, 3Medicine, Division of Rheumatology, Tufts Medical Center, Boston, MA, 4Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, 5Tufts Medical Center, Boston, MA, 6Biostatistics, Boston University School of Public Health, Boston, MA, 7Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: For some rheumatologic diseases (e.g. lupus), separate scores evaluate cumulative damage and disease activity.  No such strategy exists for osteoarthritis (OA).  The prevailing approach…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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