Abstract Number: 444 • 2018 ACR/ARHP Annual Meeting
Trajectories of Sport or Recreational Activities over Eight Years and Associated Factors in Persons at Risk for Knee Osteoarthritis
Background/Purpose: Participation in exercise, sport or recreational activities offers multiple health benefits, promotes wellbeing and weight management, and preserves function and quality of life. Staying…Abstract Number: 445 • 2018 ACR/ARHP Annual Meeting
Interleukin-1β Inhibition with Canakinumab Associates with Reduced Rates of Total Hip and Knee Replacement (THR/TKR) and Osteoarthritis (OA) Symptoms: Exploratory Results from the Canakinumab Anti-Inflammatory Thrombosis Outcomes Study (CANTOS)
Background/Purpose: In osteoarthritis (OA), there are no therapeutics to prevent disease progression. Canakinumab, a monoclonal antibody targeting interleukin-1β, reduced inflammation and cardiovascular events in the…Abstract Number: 446 • 2018 ACR/ARHP Annual Meeting
Participation in American Football Is Associated with Increased Risk for Knee Pain and Osteoarthritis: Data from the Osteoarthritis Initiative
Background/Purpose: Male youth commonly participate in American football. Little data inform whether this is associated with knee pain or osteoarthritis (OA) later in life. We…Abstract Number: 447 • 2018 ACR/ARHP Annual Meeting
Discriminating between Central & Peripheral Pain Sensitization Using a Slowly Repeated Evoked Pain Protocol
Background/Purpose: In a prior study, the response of pain sensitization by fibromyalgia (FM) patients to a protocol of Slowly Repeated Evoked Pain (SREP)* was strongly…Abstract Number: 448 • 2018 ACR/ARHP Annual Meeting
Tizanidine, a Frequently Used Muscle Relaxant, Is Associated with Severe Hypotension: Role of Cytochrome P450 1A2 Inhibition in Routine Clinical Practice
Background/Purpose: Tizanidine, a muscle relaxant widely used for musculoskeletal pain, can lower blood pressure and is metabolized by the cytochrome P450 1A2 (CYP1A2). As a…Abstract Number: 449 • 2018 ACR/ARHP Annual Meeting
Pain Processing in Chronic Low Back Pain Individuals with or without Sick Leave
Background/Purpose: Chronic low back pain (LBP) is one of the most common musculoskeletal complaints in industrialized societies. It affects 80% of the adult population at…Abstract Number: 450 • 2018 ACR/ARHP Annual Meeting
Injection Site Reaction Associated with Subcutaneous Biologic Agents and Methotrexate. Analysis from the Rhumadata® Clinical Database and Registry
Background/Purpose: Injection Site Reaction (ISRs) are associated with the subcutaneous (SC) route of administration of all biologic agents, and 3% to 15% of patients reports…Abstract Number: 451 • 2018 ACR/ARHP Annual Meeting
The Frequency of Neuropathic Pain in Patients with Low Back Pain and the Relationship with Demographic Characteristics: A Cross-Sectional Study
Background/Purpose: Low back pain (LBP) is one of the most challenging chronic pain conditions. The pathophysiology of LBP is complex and contains nociceptive and neuropathic…Abstract Number: 452 • 2018 ACR/ARHP Annual Meeting
Features of Peripheral and Central Sensitization and Neuropathic Pain Are Seen in Both Osteoarthritis and Rheumatoid Arthritis
Background/Purpose: OA and RA are among the most common chronic painful rheumatic diseases. Appreciation of the role of pain sensitization in OA has revolutionized the…Abstract Number: 453 • 2018 ACR/ARHP Annual Meeting
Profound Changes in the NaV1.8 Nociceptive Innervation of the Murine Knee Joint after Destabilization of the Medial Meniscus
Background/Purpose: We aimed to compare the nociceptive innervation of healthy and osteoarthritic mouse knees. Methods: Destabilization of the medial meniscus (DMM) or sham surgery was…Abstract Number: 454 • 2018 ACR/ARHP Annual Meeting
Effects of Prolonged Chemogenetic Inhibition of Nociceptors in a Murine Surgical Model of Osteoarthritis
Background/Purpose: The aim of this study was to investigate the effects of prolonged chemogenetic inhibition of NaV1.8 nociceptors on pain-related behaviors and cellular changes in…Abstract Number: 455 • 2018 ACR/ARHP Annual Meeting
Metabolic Syndrome and Trajectories of Pain Severity and Number of Painful Sites in Knee Osteoarthritis: Data from a 10.7-Year Prospective Study
Background/Purpose: Metabolic syndrome (MetS) has been suggested as having a role in osteoarthritis (OA) pathogenesis. No study has assessed whether MetS and its components are…Abstract Number: 456 • 2018 ACR/ARHP Annual Meeting
Effect of Local and Systemic CCR2 Blockade on Knee Hyperalgesia in a Mouse Model of Osteoarthritis
Background/Purpose: Surgical destabilization of the medial meniscus (DMM) in the mouse knee results in slowly progressive osteoarthritis (OA), characterized by moderate joint damage by week…Abstract Number: 457 • 2018 ACR/ARHP Annual Meeting
Neuropathic Pain in Patients with Knee Osteoarthritis (Preliminary Report)
Background/Purpose: There are limited studies in the literature indicating that neuropathic pain occurs in knee osteoarthritis (OA) (1). The aim of this cross sectional study…Abstract Number: 458 • 2018 ACR/ARHP Annual Meeting
Validation of the 2012 Systemic Lupus International Collaborating Clinics (SLICC) Classification Criteria Compared to the 1997 Acr Criteria and 2017 Candidate Weighted Criteria for Lupus in Pediatric Patients
Background/Purpose: Different classification criteria for systemic lupus erythematosus (SLE) have been proposed over many years. The most widely used and accepted criteria have been the…
ACR Meeting Abstracts