Abstracts Archive - Page 1176 of 2607 - ACR Meeting Abstracts

Abstract Number: 599 • 2019 ACR/ARP Annual Meeting
Muscle Physical Properties in Young Adult Axial Spondyloarthritis Patients, the MyoSpA Study
Fernando Pimentel-Santos¹, Agna Neto ², Lúcia Domingues ³, Atlas Sardoo ³, Santiago Rodrigues-Manica ¹, Rita Pinheiro Torres ⁴, Carolina Crespo ⁵, Alexandre Sepriano ⁶, Sofia Ramiro ⁷, Kalyani Nair ⁸, Júlia Costa ⁹, Patrícia Gomes-Alves ¹⁰, Alfonse Masi ¹¹ and Jaime Branco ¹, ¹CEDOC, NOVA-Medical School | Hospital Egas Moniz, CHLO, Lisbon, Lisbon, Portugal, ²Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon; Hospital Central do Funchal, Madeira., Lisbon, Portugal, ³CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon, Lisbon, Portugal, ⁴Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon., Lisbon, Portugal, ⁵CEDOC, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal, Lisbon, Portugal, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, ⁸Bradley University and University of Illinois College of Medicine at Peoria, Illinois, USA, Peoria, IL, ⁹Instituto de Tecnologia Química e BiológicaAntónio Xavier, Universidade NOVA de Lisboa, Av. República, 2780-157 Oeiras, Portugal, Oeiras, Portugal, ¹⁰Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, ¹¹University of Illinois College of Medicine at Peoria and Bradley University, Peoria Illinois, USA, Peoria, IL
Background/Purpose: An important mechanism regarding axial spondyloarthritis (axSpA) susceptibility and progression is the biomechanical concept, suspected from axial myofascial hypertonicity and stiffness in ankylosing spondylitis…
Abstract Number: 600 • 2019 ACR/ARP Annual Meeting
Frequency of Disease Flares Under Long-Term Anti-TNF Therapy in Patients with Early Axial Spondyloarthritis: Results from the Etanercept versus Sulfasalazine in Early Axial Spondyloarthritis Trial (ESTHER)
Fabian Proft¹, Murat Torgutalp ², Anja Weiß ³, Mikhail Protopopov ⁴, Valeria Rios Rodriguez ⁵, Hildrun Haibel ¹, Kay-Geert Hermann ⁵, Christian Althoff ⁵, Olaf Behmer ⁶, Joachim Sieper ¹ and Denis Poddubnyy ⁷, ¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Germany and Ankara University Faculty of Medicine, Ankara, Turkey., Berlin, Germany, ³German Rheumatism Research Center (DRFZ), Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ⁵Charité Universitätsmedizin, Berlin, Germany, ⁶Pfizer Inc., Berlin, Germany, ⁷Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: Disease flares in axial spondyloarthritis (axSpA) might occur even in patients with otherwise stable disease receiving effective anti-inflammatory therapy such as TNF inhibitors. The…
Abstract Number: 601 • 2019 ACR/ARP Annual Meeting
Development of an Optimized Online Self-Referral Tool for Early Recognition of Patients with Axial Spondyloarthritis – Data from the OptiRef Study
Fabian Proft¹, Laura Spiller ², Mikhail Protopopov ³, Valeria Rios Rodriguez ², Burkhard Muche ², Judith Rademacher ², Susanne Lüders ², Anne Katrin Weber ², Imke Redeker ⁴ and Denis Poddubnyy ⁵, ¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ²Charité Universitätsmedizin, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ⁴Charité – Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, ⁵Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: One of the major reasons for a long diagnostic delay in axial spondyloarthritis (axSpA) is the late referral of patients by primary care physicians…
Abstract Number: 602 • 2019 ACR/ARP Annual Meeting
Comparison of Men and Women with Axial Spondyloarthritis in the US-Based Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry
Philip Mease¹, Mei Liu ², Sabrina Rebello ², Robert McLean ², Blessing Dube ², Meghan Glynn ³, Esther Yi ⁴, Yujin Park ⁵ and Alexis Ogdie ⁶, ¹Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA, ²Corrona, LLC, Waltham, MA, ³Corrona, LLC, Waltham, ⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁵Novartis Pharmaceuticals Corporation, East Hanover, ⁶Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease that primarily affects the axial skeleton and frequently affects the peripheral joints and entheses. AxSpA…
Abstract Number: 603 • 2019 ACR/ARP Annual Meeting
Are the Modified New York and ASAS Criteria Interchangeable in the Classification of Patients with Spondyloarthritis with Radiographic Sacroiliitis?
Anne Boel¹, Anna Moltó ², Désirée van der Heijde ³, Adrian Ciurea ⁴, Maxime Dougados ⁵, Lianne Gensler ⁶, Maria José Santos ⁷, Eugenio de Miguel ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Astrid van Tubergen ¹¹, Floris van Gaalen ³ and Sofia Ramiro ¹², ¹Leiden University Medical Centre, Leiden, Netherlands, ²Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Hospital Zürich, Zürich, Switzerland, ⁵Cochin Hospital, Paris, France, ⁶University San Francisco California, San Francisco, CA, ⁷Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ⁸Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Maastricht University Medical Centre and Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands, ¹²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands
Background/Purpose: Patients with axial spondyloarthritis (axSpA) with radiographic sacroiliitis may be classified using the modified New York (mNY) criteria as ankylosing spondylitis and using the…
Abstract Number: 604 • 2019 ACR/ARP Annual Meeting
Do Illness Perceptions and Coping Change over Time in Patients Recently Diagnosed with Axial Spondyloarthritis? A 2-Year Follow-Up Study in the SPACE Cohort
Miranda van Lunteren¹, Robert B.M. Landewé ², Camilla Fongen ³, Roberta Ramonda ⁴, Désirée van der Heijde ¹ and Floris van Gaalen ¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Amsterdam University Medical Center, Amsterdam, Netherlands, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴University of Padova, Padova, Italy
Background/Purpose: We have previously shown that in patients with recently diagnosed axial SpA (axSpA), illness perceptions had a negative impact on the relationship between back…
Abstract Number: 605 • 2019 ACR/ARP Annual Meeting
Macrophage Migration Inhibitory Factor Is a Critical Regulator in a Mouse Model of Spondyloarthritis
Akihiro Nakamura¹, Fanxing Zeng ¹, Sayaka Nakamura ¹, Richard Bucala ² and Nigil Haroon ³, ¹University Health Network, Toronto, Canada, ²Yale University School of Medicine, New Haven, CT, ³Toronto Western Hospital, Krembil Research Institute, University of Toronto, Toronto, ON, Canada
Background/Purpose: Spondyloarthritis (SpA) is a chronic rheumatic disease characterized by severe inflammation in the spine, peripheral joints, intestine, skin and eyes. Although current treatment modalities…
Abstract Number: 606 • 2019 ACR/ARP Annual Meeting
Effectiveness of TNFi After a First Switch in Patients with Early Axial Spondyloarthritis: A Longitudinal Analysis of the DESIR Cohort
Marion Pons ¹, Sylvie Chevret ², Karine Briot ³, Maria-Antonietta D’Agostino ⁴, Christian Roux ⁵, Maxime Dougados ⁶ and Anna Moltó⁵, ¹Rheumatology department, Cochin Hospital, Paris, Paris, Ile-de-France, France, ²INSERM U-1153, CRESS Paris-Sorbonne, Paris, Paris, Ile-de-France, France, ³Rheumatology department, Cochin Hospital, Paris, France, Paris, Ile-de-France, France, ⁴Department of Rheumatology, APHP, Hôpital Ambroise Paré, Paris, France, ⁵Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁶Cochin Hospital, Paris, France
Background/Purpose: Contradictory data has been reported on the effectiveness of a second and third line of TNFi in early axial spondyloarthritis (axSpA). The objective of…
Abstract Number: 607 • 2019 ACR/ARP Annual Meeting
Expansion of Peripheral Cytotoxic T Cells in Co-morbid Inflammatory Bowel Disease and Spondyloarthritis
Adam Lefferts¹, Emilie Regner ², Andrew Stahly ³, Rebecca O'Rourke ¹, Kenneth Jones ² and Kristine Kuhn ¹, ¹University of Colorado, Anschutz Medical Campus, Aurora, CO, ²University of Colorado, Anschutz Medical Campus, Denver, CO, ³University of Colorado, Aurora, CO
Background/Purpose: Background: The clinical overlap of axial spondyloarthritis (axSpA) and Crohn’s disease (CD) has given rise to the hypothesis that these conditions may share pathophysiologic…
Abstract Number: 608 • 2019 ACR/ARP Annual Meeting
Prevalence of Radiographic Entheseal Lesions at the Hip and Pelvic Region in Patients with Ankylosing Spondylitis versus Controls
Freke Wink¹, Thomas Diemel ², Suzanne Arends ² and Anneke Spoorenberg ², ¹Medical Center Leeuwarden, Leeuwarden, Netherlands, ²University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Enthesitis is one of the features of ankylosing spondylitis (AS). High prevalence of structural and inflammatory ultrasound lesions of peripheral entheses are found in…
Abstract Number: 609 • 2019 ACR/ARP Annual Meeting
Baseline Characteristics and Natural History of Radiographic versus Non-radiographic Axial Spondyloarthritis: 5 Years Follow-up of the Desir Cohort
Clementina López-Medina¹, Anna Moltó ², Pascal Claudepierre ³ and Maxime Dougados ⁴, ¹Cochin Hospital, Rheumatology Department, Paris, France, ²Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ³Rheumatology, CHU Henri Mondor Créteil, Paris, France, ⁴Cochin Hospital, Paris, France
Background/Purpose: There is still a debate concerning the concept of non-radiographic (nr-axSpA) axial Spondyloarthritis (e.g. to consider it as a distinct entity from r-axSpA (Ankylosing…
Abstract Number: 610 • 2019 ACR/ARP Annual Meeting
Ankylosing Spondylitis-associated Killer Immunoglobin-like Receptors Are Strongly Expressed on γδ T Cells
Micah Lefton¹, Nihaarika Sharma ¹ and Joerg Ermann ², ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston
Background/Purpose: The mechanism underlying the association between ankylosing spondylitis (AS) and HLA-B27 is still unknown. One of the hypotheses involves the interaction of HLA-B27 homodimers…
Abstract Number: 611 • 2019 ACR/ARP Annual Meeting
Retina of Ankylosing Spondylitis Patients Shows Early Signs of Atherosclerotic Disease in Comparison with Healthy Controls
Rianne van Bentum¹, Milad Baniaamam ², Buket Kinaci-Tas ³, Aleid van de Kreeke ⁴, Merve Kocyigit ¹, Pieter Jelle Visser ⁵, Erik Serné ⁶, Frank Verbraak ⁷, Mike Nurmohamed ⁸ and Irene van der Horst-Bruinsma ¹, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, Rheumatology, Reade, Amsterdam|Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ³Opthalmology dpt., Amsterdam University Medical Center, location AMC, Amsterdam, Amsterdam, Netherlands, ⁴Ophthalmology dpt., Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁵Dpt. of Clinical Chemistry, Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁶Dpt. Internal Medicine, Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁷Ophthalmology dpt., Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁸Amsterdam Rheumatology and immunology Center location Reade and Amsterdam UMC location VU medical center, Amsterdam, Netherlands
Background/Purpose: Chronic systemic inflammation in patients with ankylosing spondylitis (AS) contributes to the development of cardiovascular disease (CVD). Early recognition of microvascular changes could improve…
Abstract Number: 612 • 2019 ACR/ARP Annual Meeting
Objective Ankylosing Spondylitis Physical Performance Index (ASPI) Is Highly Reliable and Feasible in Chilean Patients
Rianne van Bentum¹, Sebastian Ibáñez Vodnizza ², Francisca Valenzuela Aldridge ², Maria Paz Poblete ³, Salima van weely ⁴, Marieke ter Wee ¹, Omar Valenzuela ⁵ and Irene van der Horst-Bruinsma ¹, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Rheumatology dpt., Clínica Alemana - UDD Medicine faculty, Santiago, Chile, ³Rheumatology dpt., Facultad de Medicina Clinica Alemana - UDD, Santiago, Region Metropolitana, Chile, ⁴Orthopedics, Rehabilitation and Physical Therapy dpt., Leiden University Medical Center, Leiden, Netherlands, ⁵Facultad de Medicina Clinica Alemana -UDD, Santiago, Region Metropolitana, Chile
Background/Purpose: In axial spondyloarthritis (axSpA), preservation of physical functioning is an important treatment goal and is usually assessed with the patient-reported BASFI questionnaire. The Ankylosing…
Abstract Number: 613 • 2019 ACR/ARP Annual Meeting
Can Fecal Calprotectin Predict Future Development of Inflammatory Bowel Disease in Axial Spondyloarthritis Patients? – TReasure Real-Life Preliminary Data
Gozde Kubra Yardımcı ¹, Ozan Cemal içaçan ², Gokhan Kabadayi ³, Bayram Farisoğulları ¹, Cemal Bes ⁴, Servet Akar ⁵ and Umut Kalyoncu⁶, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, ²University of Health Sciences, Bakırköy Sadi Konuk Research and Training Hospital, Rheumatology, İstanbul, ³Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ⁴University of Medical Sciences, İstanbul, Turkey, ⁵Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, ⁶Hacettepe University Department of Rheumatology, Ankara, Turkey
Background/Purpose: Inflammatory bowel disease (IBD) is frequently seen in patients with axial spondyloarthritis (axSpA). This study aimed to investigate whether fecal calprotectin levels could predict…

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