ACR Meeting Abstracts

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  • Abstract Number: 2408 • 2018 ACR/ARHP Annual Meeting

    Comparison of the Tear Cytokine and Chemokine Profile of Children with JIA and JIA-Associated Uveitis

    Sheila Angeles-Han1, Virginia Miraldi Utz2, Sherry Thornton3, Alyssa Sproles3, Najima Mwase4, Theresa Hennard3, Mekibib Altaye4 and Gary Holland5, 1Rheumatology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, 2Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, 3Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Jules Stein Eye Institute, Jules Stein Eye Institute, University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: Children with JIA are at increased risk for uveitis. Known risk factors do not accurately stratify risk. Biomarkers are needed to predict uveitis development…
  • Abstract Number: 2409 • 2018 ACR/ARHP Annual Meeting

    Do Children with Juvenile Idiopathic Arthritis Play an Active Role in Their Treatment Adherence? First Results of the Rumaji Study

    Guillaume Montagu1, Ellie Mevel1, William FAHY2, Linda Rossi-Semerano3, Elisabeth Solau-Gervais4, Sonia Tropé5 and Jean-David Cohen6, 1Research, Unknowns, strategy and innovation consulting, PARIS, France, 2KOURIR, Paris, France, 3Paediatric Rheumatology, Hôpital Kremlin Bicêtre, PARIS, France, 4Service de Rhumatologie, CHRU de Poitiers, Poitiers, France, 5149 avenue du Maine, ANDAR, Paris, France, 6IMMUNO-RHEUMATOLOGY, CHU LAPEYRONIE, MONTPELLIER, France

    Background/Purpose: Adherence to DMARDs such as methotrexate and biologics is critical for patients with Juvenile Idiopathic Arthritis (JIA). Notwithstanding, few studies exists on that topic…
  • Abstract Number: 2410 • 2018 ACR/ARHP Annual Meeting

    Determining the Need for Fatigue Management Resources for Young Adults with Rheumatic Disease

    Kristine Carandang1 and Janet L. Poole2, 1Chan Division of Occupational Science & Occupational Therapy, University of Southern California, Los Angeles, CA, 2Health Sciences Ctr OT Program, University of New Mexico, Albuquerque, NM

    Background/Purpose: Fatigue is a multi-faceted symptom of rheumatic disease that has high priority among patients due to its far-reaching effects on roles and relationships. There…
  • Abstract Number: 2411 • 2018 ACR/ARHP Annual Meeting

    The Ovarian Reserve Measuring the Anti-Müllerian Hormone Is Not Diminished in Patients with Rheumatoid Arthritis Compared to the Healthy Population

    Mireia López-Corbeto1, Sara Marsal1, Andrea Pluma2, Sergio Martinez2, Maria Lopez-Lasanta2, Agusti Sellas-Fernandez2, Juan José de Agustín2 and Mireia Barcelo2, 1Rheumatology Research Group, Vall d'Hebron Hospital Research Institute, Barcelona, Spain, 2Vall d'Hebron Hospital Research Institute, Barcelona, Spain

    Background/Purpose: Rheumatoid Arthritis (RA) is the most prevalent chronic inflammatory arthritis, affecting 0.5-1% worldwide population and predominates in females. Altered fertility has been reported due…
  • Abstract Number: 2412 • 2018 ACR/ARHP Annual Meeting

    Evaluating Gaps in Reproductive Health Knowledge Among Women with Rheumatic Diseases

    Mehret Birru Talabi1, Megan E. B. Clowse2, Susan J. Blalock3, Lan Yu4, Alaina Chodoff5 and Sonya Borrero4, 1Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, 3Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 4Medicine, University of Pittsburgh, Pittsburgh, PA, 5General Internal Medicine, UPMC, Pittsburgh, PA

    Background/Purpose: While women with rheumatic diseases may face considerable reproductive health challenges, few studies have objectively assessed what these women know about their reproductive risks.…
  • Abstract Number: 2413 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Mixed Connective Tissue Disease: Results from a Multicentre Cohort Study

    Massimo Radin1, Karen Schreiber2, Maria Jose Cuadrado3, Irene Cecchi4, Laura Andreoli5, Franco Franceschini6, Maria Teresa Caleiro7, Danieli Andrade8, Elena Gibbone9, Munther A Khamashta10, Jill P. Buyon11, Peter M. Izmirly12, Maria Aguirre13, Chiara Benedetto9, Dario Roccatello14, Luca Marozio15 and Savino Sciascia16, 1Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 2Department of Thrombosis and Haemophilia, Guy's and St Thomas' Hospital, London, United Kingdom., London, United Kingdom, 3Clinica Universidad de Navarra, Madrid, Spain, 4Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 5Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy, Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 6Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy, Rheumatology and Clinical Immunology, Brescia, Italy, 7Rheumatology, University of São Paulo, Tucson, AZ, 8Rheumatology, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 9University of Turin, Turin, Italy, 10Graham Hughes Lupus Research Laboratory, The Rayne Institute, London, United Kingdom, 11Medicine, New York University School of Medicine, New York, NY, 12NYU Langone Health, New York, NY, 13IMIBIC, Cordoba, Cordoba, Spain, 14Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy, 15University of Turin, Torino, Italy, 16Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy

    Background/Purpose: Mixed connective tissue disease (MCTD) is characterized by signs and symptoms of a combination of disorders, primarily systemic lupus erythematosus (SLE), scleroderma and polymyositis…
  • Abstract Number: 2414 • 2018 ACR/ARHP Annual Meeting

    The Global Antiphospholipid Syndrome Score in Women with Systemic Lupus Erythematosus and Adverse Pregnancy Outcomes

    Karen Schreiber1, Massimo Radin2, Irene Cecchi3, Elena Rubini4, Dario Roccatello5, Søren Jacobsen6, Maria Jose Cuadrado7 and Savino Sciascia8, 1Department of Thrombosis and Haemophilia, Guy's and St Thomas' Hospital, London, United Kingdom., London, United Kingdom, 2Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 3Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 4Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bosco Hospital, Turin, Italy., Turin, Italy, 5Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy, 6University of Copenhagen, Copenhagen, Denmark, 7Clinica Universidad de Navarra, Madrid, Spain, 8Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy

    Background/Purpose: Systemic lupus erythematosus (SLE) and antiphospholipid antibodies (aPL) are associated with pregnancy complications. Methods: 143 women ever pregnant with SLE who presented in our…
  • Abstract Number: 2415 • 2018 ACR/ARHP Annual Meeting

    Increased Sperm DNA Fragmentation in Male Systemic LUPUS Erythematosus Patients

    Bruno C Tiseo1, Clovis A Silva2, Eduardo Ferreira Borba3, Gabriela A Munhoz3, Miguel Srougi1, Eloisa Bonfa4 and Marcello Cocuzza1, 1Discipline of Urology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, 2Pediatric Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 3Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 4Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Gonadal dysfunction may affect male systemic lupus erythematosus (SLE) patients. Recently, sperm DNA integrity analysis has shown better diagnostic and prognostic performance for predicting…
  • Abstract Number: 2416 • 2018 ACR/ARHP Annual Meeting

    Good Pregnancy and Neonatal Outcomes in Lupus Nephritis Patients with Complete Remission

    Weixin HU, Kang LI, Yinghua CHEN, Zhenzhao LIU, Liu YANG, Duqun CHEN and Haitao Zhang, National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China

    Background/Purpose: To investigate the outcomes of pregnancy and neonatal and the risk factors of lupus flares and pregnancy complications in Chinese patients with lupus nephritis…
  • Abstract Number: 2417 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Systemic Lupus Erythematous and Pre-Systemic Lupus Erythematous: A Population-Based Cohort Study

    A. Nicole Wade1, Mary A. De Vera2, Eric C. Sayre3 and J. Antonio Avina-Zubieta4, 1Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 3Arthritis Research Canada, Richmond, BC, Canada, 4Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: The adverse effects of systemic lupus erythematosus (SLE) on maternal and fetal outcomes in pregnancy have been explored mainly in clinic-based cohorts. However, data…
  • Abstract Number: 2418 • 2018 ACR/ARHP Annual Meeting

    Awareness of Fertility and Contraception Issues Among Women with Rheumatologic Diseases

    Christina Payne1, Meagan Clark2, Sneha Patel3, Tanya Allawh3, Mei-An Ty-Arias2, Ashley Davis2 and Arundathi ‎ Jayatilleke ‎4, 1Rheumatology, Drexel University COM/ HUH, Philadelphia, PA, 2Drexel University COM, Philadelphia, PA, 3Internal Medicine, Drexel University COM, Philadelphia, PA, 4Rheumatology, Drexel University COM, Philadelphia, PA

    Background/Purpose: Because many autoimmune conditions preferentially affect women of childbearing age and both disease and treatment can negatively affect pregnancy outcomes, healthcare providers to women…
  • Abstract Number: 2419 • 2018 ACR/ARHP Annual Meeting

    Needs Assessment and Implementation of a Reproductive Health Intention Screen for Women with Systemic Rheumatic Diseases

    Elizabeth Janiak1, Latoya Bartlett2, Joy Gulla2, Bill Albert3, Sonali Desai4, Susan Ritter5, Laura Tarter5, Jonathan Coblyn5, Bonnie L. Bermas6, Wan-Ju Wu1, Caryn Dutton1, Lydia Pace7 and Candace H. Feldman4, 1Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Power to Decide, Washington, DC, DC, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 6Rheumatology, University of Texas, Southwestern, Dallas, TX, 7Division of Women's Health, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Among women with systemic rheumatic diseases (SRD), poor maternal and fetal outcomes may occur if disease activity and medication use are not optimized preconception.…
  • Abstract Number: 2420 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcome and Perinatal Complications of Neonate Born to Mothers with Juvenile Idiopathic Arthritis in Asia

    Chao-Yi Wu1, Shang-Chun Changchien2, Huang-Yu Yang3, Kuo-Wei Yeh4 and Jing-Long Huang1,2, 1Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 2Medicine, Chang-Gung University, Taoyuan city, Taiwan, 3Department of Nephrology,, Chang-Gung Memorial Hospital, Taoyuan city, Taiwan, 4Division of Allergy, Asthma and Rheumatology. Department of Pediatrics, Chang-Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the leading pediatric rheumatic disease affecting 30 out of a million women. Although spontaneous remission may occur in most…
  • Abstract Number: 2421 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Women with Rheumatic Diseases and Thrombophilia Treated in a Multidisciplinary Unit

    Isabel Añón Oñate1, Irene Notario1, Miguel Ángel Ferrer1, Lorena Pérez1, María Ramírez1 and Rafael Cáliz2, 1Rheumatology, Hospital Universitario Virgen de las Nieves, Granada, Spain, 2Hospital Universitario Virgen de las Nieves, Granada, Spain

    Background/Purpose: To evaluate the efficacy of the treatment on the pregnancy outcomes of women with Rheumatic Diseases and Thrombophilia from a Spanish cohort. Their pregnancies…
  • Abstract Number: 2422 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Patients with Interstitial Lung Disease Related to Autoimmune Disease and Sarcoidosis

    Stephanie L. Giattino, Amanda M. Eudy and Megan E. B. Clowse, Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC

    Background/Purpose: Currently published data regarding pregnancy outcomes in patients with interstitial lung disease (ILD) related to autoimmune disease and sarcoidosis is limited, with widely variant…
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