ACR Meeting Abstracts

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  • Abstract Number: 434 • 2019 ACR/ARP Annual Meeting

    Ixekizumab Significantly Improves Patient-reported Overall Health as Measured by SF-36 in Patients with Active Ankylosing Spondylitis/Radiographic Axial Spondyloarthritis: 52-Week Results of Two Phase 3 Trials

    Cheng-Chung Wei1, Theresa Hunter 2, Filip Van den Bosch 3, Jessica Walsh 4, Uta Kiltz 5, Yan Dong 6, David Sandoval 6, Luis Leon 6, Vibeke Strand 7 and Xiaoqi Li 2, 1Chung Shan Medical University, Taichung City, Taiwan (Republic of China), 2Eli Lilly and Company, Indianapolis, 3Ghent University Hospital, Ghent, Belgium, 4Division of Rheumatology, University of Utah, Salt Lake City, UT, 5Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, 6Eli Lilly and Company, Indianapolis, IN, 7Division of Immunology/Rheumatology, Stanford University, Stanford, CA

    Background/Purpose: Previous trials have used the Short Form (SF)-36 questionnaire to evaluate the impact of ankylosing spondylitis/radiographic axial spondyloarthritis (AS/r-axSpA) on health-related quality of life…
  • Abstract Number: 435 • 2019 ACR/ARP Annual Meeting

    Understanding Which Patient-Reported Outcomes Are Important to Rheumatology Patients: Findings from ArthritisPower

    W. Benjamin Nowell1, Carol Gaich 2, Kelly Gavigan 1, Zhihong Cai 2, Anabela Cardoso 2, Theresa Hunter 3, Julie Birt 2, Jennifer Workman 2 and Jeffrey Curtis 4, 1Global Healthy Living Foundation, Upper Nyack, NY, 2Eli Lilly and Company, Indianapolis, IN, 3Eli Lilly and Company, Indianapolis, 4University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Patient-reported outcomes (PROs) are important indicators of treatment effectiveness and their role is increasing in comparative effectiveness studies. Little is known about PRO measures…
  • Abstract Number: 436 • 2019 ACR/ARP Annual Meeting

    Poor Concordance Between Remission Judged by Physicians and a Patient-Acceptable Symptom State in Psoriatic Arthritis

    Rubén Queiro1, Estefania Pardo 1, Lilyan Charca 1, Sara Alonso 1, L. Arboleya 2 and Mercedes Alperi-López 1, 1Hospital Universitario Central de Asturias, Oviedo, Spain, 2Hospital Central Asturias, OViedo

    Background/Purpose: Both the evaluation of disease activity in psoriatic arthritis (PsA) and the determination of the impact of the disease on patients' lives are subjects…
  • Abstract Number: 437 • 2019 ACR/ARP Annual Meeting

    Is There Any Relationship Between Cardiovascular Comorbidity and a Patient-Acceptable Symptom State in Psoriatic Arthritis?

    Rubén Queiro1, Estefania Pardo 1, Lilyan Charca 1, Sara Alonso 1, L. Arboleya 2 and Mercedes Alperi-López 1, 1Hospital Universitario Central de Asturias, Oviedo, Spain, 2Hospital Central Asturias, OViedo

    Background/Purpose: Psoriatic arthritis (PsA) is accompanied by a high prevalence cardiovascular (CV) comorbidity. This comorbidity has been associated with worse therapeutic results as well as…
  • Abstract Number: 438 • 2019 ACR/ARP Annual Meeting

    Longitudinal Construct Validity and Responsiveness of MDHAQ and HAQDI in PsA: Can MDHAQ Replace HAQDI?

    Marilyn Wan1, Jessica Walsh 2, M. Elaine Husni 3, Jose Scher 4, Soumya Reddy 5 and Alexis Ogdie 6, 1University of Pennsylvania, Philadelphia, 2Division of Rheumatology, University of Utah, Salt Lake City, UT, 3Department of Rheumatologic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 4Division of Rheumatology, New York University School of Medicine and NYU Langone Orthopedic Hospital, New York, NY, 5Division of Rheumatology, New York University School of Medicine, New York, NY, 6Department of Medicine and Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

    Background/Purpose: The multi-dimensional health assessment questionnaire (MDHAQ) is a patient-reported outcome that is commonly used in clinical practice in the US and comprises of 10…
  • Abstract Number: 439 • 2019 ACR/ARP Annual Meeting

    Improved Patient-Reported Outcomes in Patients with Persistently Active Rheumatoid Arthritis Following Treatment with Repository Corticotropin Injection

    Daniel Furst1, George Wan 2, Jingyu Liu 3, Julie Zhu 3, Laura Bartels-Peculis 3, Mary Panaccio 3 and Roy Fleischmann 4, 1University of California, Los Angeles, CA, 2Mallinckrodt Pharmaceuticals, Bedminster, NJ, 3Mallinckrodt Pharmaceuticals, ARD, LLC, Bedminster, NJ, 4Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disorder characterized by progressive inflammation and irreversible joint damage. Treatment of active disease includes disease-modifying anti-rheumatic drugs (DMARDs)…
  • Abstract Number: 440 • 2019 ACR/ARP Annual Meeting

    Disease Activity and Quality of Life in Behçet’s Syndrome: The Role of Patient Reported Outcome

    Antonio Figliomeni1, Alice Parma 1, Viola Signorini 2, Emanuele Calabresi 1, Rosaria Talarico 1 and Marta Mosca 3, 1Università di Pisa, PISA, Italy, 2Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, pisa, Toscana, Italy, 3Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, Pisa, Italy

    Background/Purpose: Behçet’s syndrome (BS) is a systemic vasculitis, characterised by recurrent oro-genital ulcers, ocular inflammation and skin manifestations; articular, vascular, gastro-enteric and neurological involvement may…
  • Abstract Number: 441 • 2019 ACR/ARP Annual Meeting

    Multidimensional Health Assessment Questionnaire (MDHAQ) Scores in Spain vs USA: Similar Scores for Clinical Status and Self-report of Depression in Rheumatoid Arthritis (RA) but Poorer Scores for Both in Spondyloarthropathies (SpA) in Spain

    Rosa Morlà1, R. Castellanos 2, Virginia Ruiz-Esquide 3, Julio Ramirez 4, Raimon Sanmarti 5, Jose Gomez-Puerta 5, Mariam Riad 6, Isabel Castrejon 6 and Theodore Pincus 6, 1Rheumatology Unit, Xarxa Sanitaria Santa Tecla, Tarragona. Rheumatology, Fundacio Clinic, Barcelona, Barcelona, Spain, 2Fundacio Clinic. Hospital Clinic de Barcelona, Barcelona, Spain, 3Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, 4Hospital Clinic, Barcelona, Spain, Barcelona, Spain, 5Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Spain, 6Division of Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose: Associations of depression with clinical status in RA1 and differences in clinical status in different countries2 have been reported.  We compared MDHAQ (multidimensional health…
  • Abstract Number: 442 • 2019 ACR/ARP Annual Meeting

    Multidimensional Health Assessment Questionnaire (MDHAQ) as an Effective Screening Tool to Identify Concomitant Depression in Patients with Rheumatoid Arthritis and Spondyloarthritis in Routine Care

    Rosa Morlà1, Mariam Riad 2, Virginia Ruiz-Esquide 3, Fernando Espi 4, Julio Ramirez 5, Nuria Del Castillo 6, Jose Gomez-Puerta 7, Raimon Sanmarti 7, Theodore Pincus 2 and Isabel Castrejon 2, 1Rheumatology Unit, Xarxa Sanitaria Santa Tecla, Tarragona. Rheumatology, Fundacio Clinic, Barcelona, Barcelona, Spain, 2Division of Rheumatology, Rush University Medical Center, Chicago, IL, 3Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, 4Rush University Medical Center, Chicago, IL, 5Hospital Clinic, Barcelona, Spain, Barcelona, Spain, 6Xarxa Social i Sanitaria de Santa Tecla, Tarragona, Spain, 7Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Spain

    Background/Purpose: Patients with rheumatoid arthritis (RA) or spondyloarthritis (SpA) are more likely to report depression than the general population, and depression has been associated with…
  • Abstract Number: 443 • 2019 ACR/ARP Annual Meeting

    Validation of a Risk Perception Questionnaire Developed for Patients with Rheumatoid Arthritis

    Irazú Contreras-Yáñez 1, Pilar Lavielle 2, Patricia Clark 3 and Virginia Pascual-Ramos1, 1Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Distrito Federal, Mexico, 2Clinical Epidemiology Unit, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City, Mexico, 3Head of the Clinical Epidemiology Unit, Hospital Infantil de México Federico Gómez-Facultad de Medicina UNAM, Mexico City, Mexico

    Background/Purpose: Treatment recommendations directed to rheumatoid arthritis patients (RA) may be more easily adopted if they are patient-centered. The adoption of health behaviors is associated…
  • Abstract Number: 444 • 2019 ACR/ARP Annual Meeting

    Criterion Validity of the Flare Assessment in Rheumatoid Arthritis (FLARE-RA) Questionnaire and FLARE-RA Cut-offs for Clinical Decision Making: International Collaboration

    Elena Myasoedova1, Annette De Thurah 2, Marie-Line Erpelding 3, Emilce Schneeberger 4, Thomas Maribo 5, Gustavo Citera 6, John Davis 1, Eric Matteson 7, Cynthia Crowson 8, Bruno Fautrel 9 and Francis Guillemin 3, 1Mayo Clinic, Rochester, MN, 2Aarhus University Hospital, Aarhus, Denmark, 3Inserm, University of Lorraine, Nancy, France, 4Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 5DEFACTUM, Aarhus, 6Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, 7Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA, Rochester, 8Mayo Clinic Rochester, Rochester, 9Pitié-Salpêtrière Hospital, Department of Rheumatology, AP-HP, Sorbonne University, UPMC university, Paris, Ile-de-France, France

    Background/Purpose: Flares are inherent to the rheumatoid arthritis (RA) disease course and associated with poor clinical outcomes including low quality of life, joint damage and…
  • Abstract Number: 445 • 2019 ACR/ARP Annual Meeting

    What Is the Effect of Statins on the Risk of Rheumatoid Arthritis? Results of a Systematic Review and Meta-Analysis

    Elena Myasoedova1, Paras Karmacharya 1, Ali Duarte Garcia 1, John Davis 1, M.Hassan Murad 1 and Cynthia Crowson 2, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic Rochester, Rochester

    Background/Purpose: The anti-inflammatory and immune-modulating effects of statins suggest that these drugs may influence the risk of developing autoimmune diseases, such as rheumatoid arthritis (RA). …
  • Abstract Number: 446 • 2019 ACR/ARP Annual Meeting

    High MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data) Scores in RA Patients Who Have Depression According to a Screening Questionnaire

    Rosa Morlà1, Mariam Riad 2, Raul Castellanos-Moreira 3, Virginia Ruiz-Esquide 4, Raimon Sanmarti 5, Jose Gomez-Puerta 6, Theodore Pincus 2 and Isabel Castrejon 2, 1Rheumatology Unit, Xarxa Sanitaria Santa Tecla, Tarragona. Rheumatology, Fundacio Clinic, Barcelona, Barcelona, Spain, 2Division of Rheumatology, Rush University Medical Center, Chicago, IL, 3Rheumatology Department. Hospital Clínic Barcelona, Barcelona, Catalonia, Spain, 4Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, 5Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Spain, 6Servei de Rheumatologia, Hospital Clinic Universtari, Barcelona, Barcelona, Catalonia, Spain

    Background/Purpose: Depression in rheumatoid arthritis (RA) patients may be pre-existent, amplified, or may develop after the onset of RA1. The Patient Health Questionnaire (PHQ9) is…
  • Abstract Number: 447 • 2019 ACR/ARP Annual Meeting

    Nail Abnormalities in a Cohort of Rheumatoid Arthritis Patients: Repetitive Trauma-Related Findings in Toenails Are Associated with Radiographic Damage

    Virginia Pascual-Ramos1, Silvia Méndez-Flores 1, Judith Domínguez-Cherit 1, Ana Gabriela Sánchez-Cárdenas 1, Ana Barrera-Vargas 2, Javier Merayo-Chalico 1 and Irazú Contreras-Yáñez 1, 1Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Distrito Federal, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico

    Background/Purpose: Different dermatological changes and nail abnormalities have been reported in rheumatoid arthritis (RA) patients, some of which are specifically associated with the disease, while…
  • Abstract Number: 448 • 2019 ACR/ARP Annual Meeting

    Central Sensitization in Patients with Rheumatoid Arthritis Using the Central Sensitization Inventory

    Kentaro Noda1, Moe Saitou 1, Taro Ukichi 1, Yohsuke Oto 1, Ken Yoshida 1 and Daitaro Kurosaka 1, 1The Jikei University School of Medicine, Tokyo, Japan

    Background/Purpose: Pain of rheumatoid arthritis (RA) is thought to be nociceptive. However, recent studies indicate that RA pain also includes the mechanism of central sensitization…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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