Abstracts Archive - Page 1151 of 2425 - ACR Meeting Abstracts

Abstract Number: 2197 • 2018 ACR/ARHP Annual Meeting
Steroid Bolus Leads to a Negative 18f-FDG PET/CT Scan in Large Vessel Vasculitis. Data from a Multicenter Giant Cell Arteritis Cohort Database
Paula Estrada¹, Patricia Moya², Hector Corominas³, Delia Reina⁴, Dacia Cerdà⁴, Daniel Roig Vilaseca⁴, Vanessa Navarro⁴, Sergi Heredia⁴ and Francisco Javier Narváez⁵, ¹Rheumatology, Hospital Moisès Broggi-Hospital General de L´Hospitalet. Consorci Sanitari Integral, Barcelona, Spain, ²Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ³Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain, ⁴Rheumatology, Hospital Moisès Broggi-Hospital General de L´Hospitalet. Consorci Sanitari Integral,, barcelona, Spain, ⁵Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain
Background/Purpose: Giant cell arteritis (GCA) and polymialgia rheumatica (PMR) are overlapping inflammatory diseases. Large Vessel Vasculitis (LVV) is frequently present in any of the two…
Abstract Number: 2198 • 2018 ACR/ARHP Annual Meeting
Evaluation of 18F-Fluorodeoxyglucose PET-CT Score at Baseline on the Therapeutic Response to Prednisone in Polymyalgia Rheumatica: A Retrospective Study
Nicolas Giraud¹, Maxime Sondag², Aline Charpentier², Hatem Boulahdour³, Clément Prati^4,5, Daniel Wendling^6,7 and Frank Verhoeven⁸, ¹Rheumatology, CHU de Besançon, Besançon, France, ²rheumatology, CHU de Besançon, Besancon, France, ³CHU de Besançon, Besançon, France, ⁴EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche Comté, Besancon, France, ⁵Rheumatology, University Hospital - Bourgogne Franche Comté University, Besancon, France, ⁶Rheumatology, University Hospital - Bourgogne Franche Comté University, Besançon, France, ⁷EA 4266, Univ. Bourgogne Franche-Comté, F-25000 Besançon, France, F-25000 Besançon, France, ⁸EA 4267 PEPITE, Université de Bourgogne Franche Comté, Besançon, France
Background/Purpose: To evaluate the impact of 18F-fluorodeoxyglucose PET-CT (FDG-PET/CT) score at baseline, on the therapeutic response to prednisone, in patients with polymyalgia rheumatica (PMR). Methods:…
Abstract Number: 2199 • 2018 ACR/ARHP Annual Meeting
Active Disease and Follow up 18f-FDG-PET/CT in Patients with Giant Cell Arteritis. Which Treatment Is More Likely to Achieve Remission?
Verena Schönau¹, Georg Schett², Matthias Englbrecht¹, Juergen Rech³ and Jessica Roth¹, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ²Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany, ³Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany
Background/Purpose: Giant cell arteritis is the most common large vessel vasculitis. 18F-FDG-PET/CT is known to be a useful imaging technique for diagnosing giant cell arteritis.…
Abstract Number: 2200 • 2018 ACR/ARHP Annual Meeting
Does an 18f-FDG-PET/CT in Patients with Giant Cell Arteritis in Clinical Remission Make Sense?
Verena Schönau¹, Jessica Roth¹, Matthias Englbrecht¹, Juergen Rech² and Georg Schett³, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, ²Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany, ³Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 – Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany
Background/Purpose: Giant cell arteritis is the most common large vessel vasculitis. 18F-FDG-PET/CT is known to be a useful imaging technique for diagnosing giant cell arteritis.…
Abstract Number: 2201 • 2018 ACR/ARHP Annual Meeting
Evaluation of 18f-Fluorodeoxyglucose Positron Emission Tomography/ Magnetic Resonance Imaging (18F-FDG PET/MRI) in C Protein-Induced Myositis Model in Mice
Jeong Yeon Kim^1,2, Jung Woo Byun³, Jae Hwan Shin³, Ji Soo Park^1,2, Ji Hye Lee², Shin Eui Kang^1,4, Hyun Jung Yoo^1,2, Eun Bong Lee², Do Won Hwang³, Yun Sang Lee³, Jin Chul Paeng³, Eun Young Lee⁵ and Yeong Wook Song^1,6, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ³Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, seoul, Korea, Republic of (South), ⁵Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), ⁶Rheumatology, Seoul National University Hospital, Seoul, Korea, Republic of (South)
Background/Purpose: Polymyositis is a chronic inflammatory myopathy with proximal muscle weakness due to lymphocyte infiltration, especially CD8 + T cells to the muscle layer. C…
Abstract Number: 2202 • 2018 ACR/ARHP Annual Meeting
The Relationship between Periodontitis and the Treatment Response to Biologics in Rheumatoid Arthritis Patients; A Post-Hoc Analysis Using [18F] Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
Masahiro Tachibana^1,2, Yukio Yonemoto³, Takahito SUTO³, Koichi OKAMURA³, Chisa OKURA³, Hideo SAKANE³ and Hirotaka CHIKUDA³, ¹Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan, ²Orthopedic Surgery, Kiryu Kosei General Hospital, Kiryu, Japan, ³Orthopaedic Surgery, Gunma University Graduate School of Medicine, MAEBASHI, Japan
Background/Purpose: Rheumatoid arthritis(RA) and periodontitis have been suggested to be related, and they share many clinical and pathologic features. Both diseases are chronic inflammatory diseases…
Abstract Number: 2203 • 2018 ACR/ARHP Annual Meeting
Atherosclerotic Inflammation in Rheumatoid Arthritis Patients: A Post-Hoc Study Using Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
Yukio Yonemoto¹, Masahiro Tachibana², Koichi OKAMURA¹, Takahito SUTO¹, Hideo SAKANE¹, Chisa OKURA¹, Tetsuya Kaneko² and Hirotaka CHIKUDA¹, ¹Orthopaedic Surgery, Gunma University Graduate School of Medicine, MAEBASHI, Japan, ²Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan
Background/Purpose: Rheumatoid arthritis (RA) has long been associated with an increased cardiovascular risk, and despite substantial improvements in disease management, its associated mortality remains high.…
Abstract Number: 2204 • 2018 ACR/ARHP Annual Meeting
Clinical Utility of a Multi-Energy Spectral CT in Crystal Arthritis
Lisa K. Stamp¹, Nigel Anderson², Fabio Becce³, Maya Rajeswari², Matthew Polson⁴, Olivier Guyen³, Anais Viry³, Chloe Choi², Tracy Kirkbride⁵ and Aamir Raja², ¹University of Otago, Christchurch, New Zealand, ²University of Otago, Christchurch, Christchurch, New Zealand, ³Lausanne University Hospital, Lausanne, Switzerland, ⁴University of Canterbury, Christchurch, New Zealand, ⁵Ara Institute of Canterbury, Christchurch, New Zealand
Background/Purpose: The gold standard for the diagnosis of crystal-related arthritis requires aspiration and visualization of crystals from synovial fluid or tophus material. However, crystal identification…
Abstract Number: 2205 • 2018 ACR/ARHP Annual Meeting
Initial Phase 2 Clinical Data of SEL-212 in Symptomatic Gout Patients: Measurement of Dissolution of Urate Deposits Associated with Monthly Dosing of a Pegylated Uricase (Pegadricase) with Svp-Rapamycin By Dual Energy Computed Tomography
Rehan Azeem¹, Earl Sands¹, Lloyd Johnston², Wesley DeHaan Ph.D.², Alan J. Kivitz³, Takashi Kei Kishimoto², Justin Park¹ and Savvas Nicolaou⁴, ¹Selecta Biosciences, Inc, Watertown, MA, ²Selecta Biosciences, Watertown, MA, ³Altoona Center for Clinical Research, Duncansville, PA, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Pegylated uricases are therapies for treatment of severe chronic gout, particularly for rapid resolution of tophi. However, uricases are limited by induction of anti-drug…
Abstract Number: 2206 • 2018 ACR/ARHP Annual Meeting
Joint Repair While Initiating Biologic Therapy in Rheumatoid Arthritis
Scott Brunet^1,2,3, Sarah Manske^1,2,3, Klaus Engelke^4,5, Steven K. Boyd^1,2,3 and Cheryl Barnabe^2,6, ¹Biomedical Engineering, University of Calgary, Calgary, AB, Canada, ²McCaig Institute for Bone and Joint Health, Calgary, AB, Canada, ³Department of Radiology, University of Calgary, Calgary, AB, Canada, ⁴Institute of Medical Physics, University of Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Department of Medicine, Erlangen University Hospital, Erlangen, Germany, ⁶Division of Rheumatology, University of Calgary, Calgary, AB, Canada
Background/Purpose: Functional decline and reduced quality of life for patients with rheumatoid arthritis (RA) results from chronic changes to joints in patients, including bone erosions…
Abstract Number: 2207 • 2018 ACR/ARHP Annual Meeting
Detecting Hand Joint Ankylosis in Radiographic Images Using Deep Learning: A Step in Development of Automatic Radiographic Scoring System for Bone Destruction
Keisuke Izumi^1,2, Masahiro Hashimoto³, Kanata Suzuki⁴, Toshio Endoh⁴, Kentaro Doi⁵, Yuki Iwai⁵, Masahiro Jinzaki³, Shigeru Ko⁶ and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ³Department of Radiology, Keio University School of Medicine, Tokyo, Japan, ⁴Machine Learning Technology Project, Artificial Intelligence Laboratory, FUJITSU LABORATORIES LTD., Kawasaki, Japan, ⁵SOLUTIONS DEVELOPMENT DEPT.I, MEDICAL SOLUTIONS DIV.V, Healthcare Solutions Unit. II, FUJITSU LTD., Tokyo, Japan, ⁶Department of Systems Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Artificial intelligence (AI) techniques including deep learning have been rapidly evolving and shown good performance in many fields over recent years. However, there are…
Abstract Number: 2208 • 2018 ACR/ARHP Annual Meeting
Novel Fluorescence Optical Imaging Scoring System of Inflammation in the Hand and Wrist Is in Patients with Rheumatoid Arthritis – Agreement with Ultrasonography and Sensitivity to Change
Mads Ammitzbøll-Danielsen¹, Daniel Glinatsi¹, Lene Terslev² and Mikkel Østergaard^3,4, ¹Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Fluorescence optical imaging (FOI) has been used for assessment of inflammation in the hands and has in several cross sectional studies been compared with…
Abstract Number: 2209 • 2018 ACR/ARHP Annual Meeting
Fluorescence Optical Imaging Xiralite® Is Helpful in the Decision for Rituximab Re-Therapy in Patients with Rheumatoid Arthritis
Sarah Ohrndorf¹, Lisa Ridha², Anne-Marie Glimm³, Gerd R. Burmester¹, Gabriela Schmittat³, Marina Backhaus⁴ and Jens Klotsche⁵, ¹Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, ⁴Department of Rheumatology & Immunology, University Medicine Charit, Berlin, Germany, ⁵Program Area Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: Rituximab (RTX) is an effective and well-tolerated therapeutic option in rheumatoid arthritis (RA) patients with insufficient response to TNFα inhibitors. However, the exact time…
Abstract Number: 2210 • 2018 ACR/ARHP Annual Meeting
Effects of Anti-Citrullinated Peptide Antibody (ACPA) on Bone Microstructure in Rheumatoid Arthritis: A HR-pQCT Study
Ikuko Tanaka¹, Takashi Kato², Motokazu Kai³, Kunikazu Ogawa³, Hiroaki Mizuno¹, Mari Ushikubo⁴, Keisuke Izumi⁵, Hisaji Oshima⁶ and Shigenori Tamaki¹, ¹Nagoya Rheumatology Clinic, Nagoya, Japan, ²Department of Radiology, National Center for Geratrics and Gerontology, Obu, Japan, ³Mie Rheumatology Clinic, Suzuka, Japan, ⁴National Tokyo Medical Center, Tokyo, Japan, ⁵Department of connective Tissue Disease, National Tokyo Medical Center, Tokyo, Japan, ⁶Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) induces systemic osteoporosis as well as osteoporotic change in the bones having arthritis by RA. Recently immune complex and anti-citrullinated peptide…
Abstract Number: 2211 • 2018 ACR/ARHP Annual Meeting
Technetium Tc 99m Tilmanocept: A Targeted Immunodiagnostic Radiopharmaceutical for the Assessment of Synovial Macrophage Activity in Rheumatoid Arthritis
Arash Kardan¹, Allison Kissling², Bonnie Abbruzzese², Ahmad Ismail², Rachael Hershey², Carley Hartings², David Ralph², Izabela Gierach², Michael Blue², Hannah Bailey², Christopher Gablemann², Katherine Repp² and Frederick Cope², ¹Charles F. Kettering Memorial Hospital and Wright State University Boonshoft School of Medicine, Dayton, OH, ²Navidea Biopharmaceuticals, Inc., Dublin, OH
Background/Purpose: Activated macrophages are a critical component of the inflammatory etiology of RA. It is well established that these macrophages perpetuate joint inflammation and destruction…

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