ACR Meeting Abstracts

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  • Abstract Number: 1776 • 2018 ACR/ARHP Annual Meeting

    Clinical Significance of Allergy in IgG4-Related Disease

    Xia Zhang1, Panpan Zhang2 and Wen Zhang3, 1Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, 2rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, 3Rheuamtology, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: IgG4-related disease (IgG4-RD) is a relatively newly defined disease entity, which can affect multiple organs and exhibit clinical heterogeneity. Recently, it has been reported…
  • Abstract Number: 1777 • 2018 ACR/ARHP Annual Meeting

    Factors Related to Deterioration of IgG4-Related Disease in Untreated Patients with IgG4-Related Disease

    Ichiro Mizushima1, Kazunori Yamada2, Satoshi Hara1, Kiyoaki Ito3, Hiroshi Fujii4 and Mitsuhiro Kawano1, 1Rheumatology, Kanazawa University Hospital, Kanazawa, Japan, 2Department of Advanced Research in Community Medicine,, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan, 3Kanazawa University Hospital, Kanazawa, Japan, 4Division of Rheumatology, Kanazawa University Hospital, Kanazawa, Japan

    Background/Purpose: In IgG4-related disease (IgG4-RD), spontaneous, or at least temporary, remissions without treatment have been reported, and watchful waiting may be appropriate in certain patients…
  • Abstract Number: 1778 • 2018 ACR/ARHP Annual Meeting

    Comparison of Clinical and Angiographic Features of Arterial Involvement in Takayasu’s Arteritis and Behcet’s Disease

    Su Jin Choi1, Doo-Ho Lim2, Ji Seon Oh1, Seokchan Hong1, Yong-Gil Kim1, Chang Keun Lee1 and Bin Yoo1, 1Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of (South)

    Background/Purpose: Systemic vasculitis is one of the major manifestations of Behcet’s disease (BD). Takayasu’s arteritis (TA) is a chronic vasculitis that primarily affects the aorta…
  • Abstract Number: 1779 • 2018 ACR/ARHP Annual Meeting

    Is the Number of IgG4+ Plasma Cells Observed By Immunostaining Important Beyond Its Diagnostic Utility in IgG4-Related Disease?

    Eduardo Martín Nares1, Jacobo Guerrero Castillo2, Arturo Angeles Angeles2 and Gabriela Hernandez-Molina1, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: The histopathological findings in IgG4-related disease (IgG4-RD) includes the presence of dense lymphoplasmacytic infiltrate, obliterative phlebitis, storiform fibrosis and the presence of marked IgG4+…
  • Abstract Number: 1780 • 2018 ACR/ARHP Annual Meeting

    Shear Wave Elastography in the Evaluation of Submandibular Gland Characteristics in IgG4-Related Disease

    Keisuke Nishimura, Keiichiro Kadoba, Hiroki Mukoyama, Rintaro Saito, Daisuke Waki and Toshihiko Yokota, Department of Endocrinoligy and Rheumatology, Kurashiki Central Hospital, Kurashiki, Japan

    Background/Purpose: IgG4-related disease (IgG4RD) is a chronic and systemic disease that can involve multiple organs. One of the most commonly involved organs are the salivary…
  • Abstract Number: 1781 • 2018 ACR/ARHP Annual Meeting

    Retrospective Analysis of IgG4-RD Patient Population at the Cleveland Clinic between 2007-2017

    Chan Mi Lee1, Mohamed Alalwani2, Richard Prayson1,3 and Carmen E. Gota1,4, 1Education, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, 2Hospital Medicine, Cleveland Clinic, Cleveland, OH, 3Anatomic Pathology, Cleveland Clinic, Cleveland, OH, 4Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH

    Background/Purpose: IgG4-related disease (IgG4-RD) is a rare multisystem fibro-inflammatory condition, characterized by organ mass lesions, IgG4+ lymphoplasmacytic infiltrate, and storiform fibrosis. To gain better understanding…
  • Abstract Number: 1782 • 2018 ACR/ARHP Annual Meeting

    Cigarette Smoking Is a Risk Factor for IgG4-Related Disease

    Rachel Wallwork1, Hyon K. Choi2, Cory A. Perugino3, Yuqing Zhang4, John H. Stone5 and Zachary Wallace6, 1Department of Medicine, Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 3Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 4Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, 5Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA, 6Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by tumefactive lesions that can occur at nearly any site, often associated with an elevated serum…
  • Abstract Number: 1783 • 2018 ACR/ARHP Annual Meeting

    Salivary Gland Disease in IgG4-Related Disease Is Associated with Allergic Histories

    Samantha Sanders1, Emanuel Della Torre2, Cory A. Perugino3, Aidan Long4, Hyon K. Choi4, John H. Stone5 and Zachary Wallace6, 1Harvard Medical School, Boston, MA, 2Unit of Medicine and Clinical Immunology, San Raffaele Scientific Institute, Milan, Italy, 3Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, 4Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, 5Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA, 6Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The etiology of IgG4-related disease (IgG4-RD) remains unknown. The role of T-helper type 2 (Th2) cells in the pathogenesis of IgG4-RD is controversial. Given…
  • Abstract Number: 1784 • 2018 ACR/ARHP Annual Meeting

    Serum IgG4 Test Characteristics: Immunonephelometry Versus Liquid Chromatography Tandem Mass Spectrometry

    Mollie Carruthers1, Andre Mattman2, Veronika Boyeva3, Liliana Cartagena4, Grace van der Gugten5, Michael Seidman2 and Luke Chen6, 1Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada, 3Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 4Mary Pack Arthritis Centre, Vancouver, BC, Canada, 5Pathology and Laboratory Medicine, St. Pauls Hospital, Vancouver, BC, Canada, 6Department of Hematology, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: IgG4-related disease (IgG4-RD) is a fibroinflammatory condition that may involve essentially any organ. The disease spectrum is also often associated with elevated serum IgG4,…
  • Abstract Number: 1785 • 2018 ACR/ARHP Annual Meeting

    A Data-Driven Approach to Guide Physicians When Considering the Differential Diagnosis of IgG4-Related Disease

    Mark A. Matza1, Zachary Wallace2 and John H. Stone3, 1Rheumatology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Rheumatology (Medicine), Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-Related Disease (IgG4-RD) is a chronic immune-mediated fibro-inflammatory disorder of unknown etiology.  The differential diagnosis is broad, partly because of the myriad potential organ…
  • Abstract Number: 1786 • 2018 ACR/ARHP Annual Meeting

    Favourable Response to Rituximab for the Treatment of IgG4-Related Disease: Long-Term Follow-up of 10 Patients Resistant to Glucocorticoids and Immunosuppressives

    Emin Oguz1, Gizem Dagcı2, Murat Erdugan1, Bahar Artim-Esen1, Ahmet Gül1, Lale Ocal1 and Murat Inanc3, 1Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 2Department of Internal Medicine, Istanbul Unıversity, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, İstanbul, Turkey

    Background/Purpose: Immunoglobulin G4-related disease (IgG4-RD) is a systemic, immuno-mediated fibro-inflammatory disease that affects various organ systems, with typical pathological findings and increased IgG4 levels. Glucocorticoids…
  • Abstract Number: 1787 • 2018 ACR/ARHP Annual Meeting

    How to Better Diagnose IgG4 Related Disease: a Single-Center Based Experience

    Anji Xiong1, Yuan Yang1, Beibei Cui1, Jianhong Sun1, Qibing Xie1, Yi Zhao1, Chunyu Tan1, Min Yang1, Yi Liu1, Honghu Tang1, Pingying Qing1, Lingshu Zhang1, Yubin Luo1, Yan Liang1, Ying Wang1, Yali Ye1, Ling Ma1, Shiyu Yi1 and Yi Liu2, 1Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, China, 2Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, Chengdu, China

    Background/Purpose: Pathology associated with IgG4-related disease (IgG4-RD) has been described in virtually every tissue and organ of the body. The heterogeneous clinical manifestations of IgG4-RD…
  • Abstract Number: 1788 • 2018 ACR/ARHP Annual Meeting

    Predictive Factors for Work-Day Loss in a Multi-Center Study in Behcet’s Disease: Indirect Costs for Healthcare

    Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: In chronic diseases, work-day loss due to health problems is associated with indirect costs for healthcare management. The aim of this multi-center study is…
  • Abstract Number: 1789 • 2018 ACR/ARHP Annual Meeting

    Mucocutaneous Activity Index As a Patient-Reported Outcome Measure in Behcet’s Disease: A Multi-Center Study from Turkey

    Haner Direskeneli, Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Organ-specific patient-reported outcome (PRO) measures may help management decisions of Behcet’s disease (BD). The aim of this prospective study was to evaluate the factors…
  • Abstract Number: 1790 • 2018 ACR/ARHP Annual Meeting

    An Unmet Need for Oral Ulcer Activity in Patients with Behcet’s Disease: A Multi-National Study

    Gonca Mumcu1, Adebowale Adesanya2, Aysun Aksoy3, Joice Moraes Faria M Belem4, Natalia Borges Cardin4, Fatma Alibaz-Oner5, Tulin Ergun6, Nevsun Inanc7, Alexandre W.S. Souza8, Wafa Madanat9, Farida Fortune10 and Haner Direskeneli7, 1Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, 2Barts and The London, School of Medicine and Dentistry, Institute of Dentistry, Clinical and Diagnostic Oral Sciences, London, UK, London, United Kingdom, 3Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 4Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, 5Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Şerifali mahallesi İbrahim Hakkı sokak. Lavella 4 sitesi. B blok, D:22 Umraniye, Istanbul, Turkey, 6Department of Dermatology, Faculty of Medicine, Marmara University, Istanbul, Turkey, 7Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 8Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, 9Jordan’s Friends of Behcet’s disease Patients Society, Medical department, Amman, Jordan, Amman, Jordan, 10Dental Institute, Barts and The London NHS Trust, London, United Kingdom

    Background/Purpose: Efficacy of current management approaches for oral ulcer treatment in routine clinical practice is insufficiently explored in Behcet’s disease (BD) patients. The aim of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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