ACR Meeting Abstracts

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  • Abstract Number: 1596 • 2018 ACR/ARHP Annual Meeting

    Atherosclerotic Cardiovascular Disease in Psoriatic Arthritis: Evaluation of Risk Factor Management and Use of Aspirin and Statin for Prevention in a Primary Care Setting

    Linh Truong1, Nicole Ridolfi1 and Maida Wong2,3, 1Internal Medicine, University of California, Irvine, Orange, CA, 2Department of Medicine, University of California, Irvine, orange, CA, 3Division of Rheumatology, Tibor Rubin Veterans Affairs Medical Center Long Beach, Long Beach, CA

    Background/Purpose: There is accumulating evidence that shows an increased prevalence of atherosclerotic cardiovascular disease (ASCVD) risk factors among the psoriatic arthritis (PsA) population. The aim…
  • Abstract Number: 1597 • 2018 ACR/ARHP Annual Meeting

    Bone Mineral Density and Serum Biomarkers of Bone Turnover in Ankylosing Spondylitis Patients Treated with Secukinumab: 2-Year Data from the Pivotal Phase 3 Study

    Jürgen Braun1, Bjoern Buehring1, Xenofon Baraliakos1, Lianne S. Gensler2, Brian Porter3, Abhijit Shete4, Erhard Quebe-Fehling5 and Sibylle Haemmerle5, 1Ruhr-University Bochum, Herne, Germany, 2University of California, San Francisco, CA, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, East Hanover, NJ, 4Novartis Pharma AG, Basel, Switzerland, Basel, Switzerland, 5Novartis Pharma AG, Basel, Switzerland

    Background/Purpose: Low bone mass is common in ankylosing spondylitis (AS) and patients (pts) with AS have an increased risk of bone fracture.1-3 Treatment of AS…
  • Abstract Number: 1598 • 2018 ACR/ARHP Annual Meeting

    Depression and Anxiety Reduce Probability of Achieving a State of Minimal Disease Activity in Patients with Psoriatic Arthritis

    Antonio Wong Lam1, Justine Y. Ye2, Dafna D Gladman1 and Vinod Chandran2, 1University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Depression and/or anxiety are comorbidities associated with psoriatic arthritis (PsA) that may affect treatment response. We aimed to determine whether the presence of depression/anxiety…
  • Abstract Number: 1599 • 2018 ACR/ARHP Annual Meeting

    Performance of Referral Strategies for Spondyloarthritis: A Population-Based Nationwide Study

    Alexandre Sepriano1,2, Sofia Ramiro1,2, Filipe Araújo3, Pedro Machado4, Ana M. Rodrigues1,5, Nélia Gouveia1,5, Mónica Eusébio5, Helena Canhão5,6 and Jaime Cunha Branco1,5, 1CEDOC, NOVA Medical School, Lisbon, Portugal, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Hospital Ortopédico de Sant ‘Ana, Cascais, Portugal, 4University College London - MRC Centre for Neuromuscular Diseases, London, United Kingdom, 5EpiReumaPt Study Group, Lisbon, Portugal, 6EPIDOC, Nova Medical School, Faculdade Ciências Médicas, Lisboa, Portugal

    Background/Purpose: Several strategies have been proposed to promote early referral of patients with SpA, but consensus on the ‘best’ strategy is yet to be achieved.…
  • Abstract Number: 1600 • 2018 ACR/ARHP Annual Meeting

    Psychometric Properties of the Assessment of Spa International Society Health Index in Patients with Active As/Radiographic Axial Spa in a Phase 3 Clinical Study

    Uta Kiltz1, Désirée van der Heijde2, Annelies Boonen3,4, Lianne S. Gensler5, Theresa Hunter6, Yan Dong6, Kathleen Wyrwich6, Hilde Carlier6 and Jürgen Braun1,7, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Leiden University Medical Centre, Leiden, Netherlands, 3Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 4Caphri Research Institute, Maastricht, Netherlands, 5University of California San Francisco, San Francisco, CA, 6Eli Lilly and Company, Indianapolis, IN, 7Ruhr Universität Bochum, Bochum, Germany

    Background/Purpose: The Assessment of SpA international Society Health Index (ASAS HI) was developed to assess function, disability, and health in patients (pts) with SpA. This…
  • Abstract Number: 1601 • 2018 ACR/ARHP Annual Meeting

    Impact of Clinical Specialty Setting and Geographic Regions on Disease Management in Patients with Psoriatic Arthritis: Results from a Cross-Sectional Observational Study in the United States

    Philip J. Mease1, Clive Liu2, Evan Siegel3,4, Heather Richmond5, Meijing Wu6, Liang Chen6, Kevin Douglas6 and Benjamin Lockshin7, 1Swedish Medical Center and University of Washington, Seattle, WA, 2Bellevue Dermatology Clinic, Bellevue, WA, 3Georgetown University, Washington, DC, 4Arthritis and Rheumatism Associates, Rockville, MD, 5Clear Dermatology, Houston, TX, 6AbbVie Inc., North Chicago, IL, 7US Dermatology Partners, Rockville, MD

    Background/Purpose: In patients (pts) with psoriatic arthritis (PsA), early diagnosis and effective treatment has been shown to decrease functional disability and structural progression (Gladman DD,…
  • Abstract Number: 1602 • 2018 ACR/ARHP Annual Meeting

    Disease Characteristics, Quality of Life, and Work Productivity By Enthesitis Sites: Real-World Data from the US Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Philip J. Mease1, Mei Liu2, Sabrina Rebello3, Winnie Hua2, Robert R. McLean2, Peter Hur4 and Alexis Ogdie5, 1Swedish Medical Center and University of Washington, Seattle, WA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Southborough, MA, 4Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA, East Hanover, NJ, 5Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Prior studies showed psoriatic arthritis (PsA) patients with enthesitis had greater disease burden than patients without enthesitis, yet it is unknown whether the impact…
  • Abstract Number: 1603 • 2018 ACR/ARHP Annual Meeting

    Gender-Specific Differences in Chinese Patients with Ankylosing Spondylitis

    Weiping Kong1, Caroline Jefferies2, Thomas Learch3, Xiaowei Gan1, Jinrui Cui4, Yuan Xu1, Dier Jin1, Yingze Zhang1, Jianming Wang1, Qingwen Tao1, Xiaoping Yan1, Michael Weisman5 and Mariko Ishimori6, 1China-Japan Friendship Hospital, Beijing, China, 2Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 3Radiology, Cedars-Sinai Medical Center, Los Angeles, CA, 4Cedars-Sinai Medical Center, Los Angeles, CA, 5Harbor UCLA Medical Center, Los Angeles, CA, 6Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA

    Background/Purpose: Growing evidence suggests gender-specific differences in the phenotypes of ankylosing spondylitis (AS). However, a literature search failed to reveal evidence of such differences in…
  • Abstract Number: 1604 • 2018 ACR/ARHP Annual Meeting

    Impact of Time to Minimal Disease Activity and Quality of Life One Year after Diagnosis of Psoriatic Arthritis

    Kim Wervers1, Jolanda J. Luime1, Ilja Tchetverikov2, Andreas H. Gerards3, M.R. Kok4, Cathelijne W. Y. Appels5, Wiebo L. van der Graaff6, Johannes H. L. M. van Groenendael7, Lindy-Anne Korswagen3, Josien J Veris-van Dieren8, JMW Hazes1 and Marijn Vis1, 1Erasmus Medical Centre, Rotterdam, Netherlands, 2Albert Schweitzer Hospital, Dordrecht, Netherlands, 3Sint Franciscus Vlietland Group, Rotterdam, Netherlands, 4Rheumatology, Maasstad Ziekenhuis, Rotterdam, Netherlands, 5Rheumatology, Amphia Hospital, Breda, Netherlands, 6Rheumatology, Rivas hospital, Gorinchem, Netherlands, 7Rheumatology, Reumazorg Zuid West Nederland, Roosendaal, Netherlands, 8Rheumatology, Reumazorg Zuid West Nederland, Goes, Netherlands

    Background/Purpose: From previous cross-sectional research we know that minimal disease activity (MDA) is associated with better health-related quality of life (HRQoL) in psoriatic arthritis (PsA).…
  • Abstract Number: 1605 • 2018 ACR/ARHP Annual Meeting

    Prevalence of Anterior Uveitis in Patients with Spondyloarthropathy in a Single US Academic Center: A Retrospective Study from Routine Care

    Ofelya Gevorgyan1, Rebecca D. Sarran2, Pauline T. Merrill2, Joel A. Block3 and Isabel Castrejon1, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Ophthalmology, Rush University Medical Center, Chicago, IL, 3Division of Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose: Acute anterior uveitis (AAU) is the most common extra-articular feature of spondyloarthropathies (SpA) over the course of the disease. Around 33% of patients with…
  • Abstract Number: 1606 • 2018 ACR/ARHP Annual Meeting

    The 66/68 Joint Count for the Measurement of MSK Disease Activity/Peripheral Joint Activity in Psa: A Grappa-Omeract Working Group Initiative

    Ali Duarte-Garcia1, Lihi Eder2, Niti Goel3, Robin Christensen4, Maarten de Wit5, Oliver FitzGerald6, Dafna D Gladman7, Richard Holland8, Ying Ying Leung9, Christine Lindsay10, Neil McHugh11, Philip J. Mease12, Ana-Maria Orbai13, Beverly Shea14, Vibeke Strand15, William Tillett16, Laura C. Coates17 and Alexis Ogdie18, 1Mayo Clinic College of Medicine and Science, Rochester, MN, 2Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada, 3Kezar Life Sciences; Duke University School of Medicine, Durham, NC, 4Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, 5EULAR standing committee of PARE, Zurich, Switzerland, 6Department of Rheumatology, St Vincent's University Hospital and Conway Institute, University College Dublin, Ireland, Dublin, Ireland, 7University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 8Royal Prince Alfred Hospital Medical Centre, Sydney, Australia, 9North District Hospital, Hong Kong, China, 10Medical Affairs, Amgen Inc, Thousand Oaks, CA, 11Rheumatology, Royal National Hospital, Bath, Great Britain, 12Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, 13Johns Hopkins University School of Medicine, Baltimore, MD, 14University of Ottawa, Ottawa, ON, Canada, 15Stanford University School of Medicine, Palo Alto, CA, 16Royal National Hospital for Rheumatic Diseases and University of Bath, Bath, United Kingdom, 17University of Oxford, Oxford, United Kingdom, 18Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: A psoriatic arthritis (PsA) core domain set to be measured in randomized controlled trials (RCT) and longitudinal observational studies (LOS) was developed by Group…
  • Abstract Number: 1607 • 2018 ACR/ARHP Annual Meeting

    Achievement of Cdapsa Low Disease Activity or Remission Is Associated with Control of Articular and Extra-Articular Manifestations of Active Psa in Subjects Treated with Apremilast

    Laura C. Coates1, Philip J. Mease2, Frank Behrens3, Ana-Maria Orbai4, Alexis Ogdie5, Michele Brunori6, Lichen Teng6, Benoit Guerette6 and Josef S. Smolen7, 1University of Oxford, Oxford, United Kingdom, 2Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, 3Division of Rheumatology, Goethe University and Fraunhofer IME-TMP, Frankfurt, Germany, 4Johns Hopkins University School of Medicine, Baltimore, MD, 5University of Pennsylvania, Philadelphia, PA, 6Celgene Corporation, Summit, NJ, 7Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria

    Background/Purpose: Therapeutic targets for psoriatic arthritis (PsA) include the achievement of remission (REM) or low disease activity (LDA), measured by the Clinical Disease Activity Index…
  • Abstract Number: 1608 • 2018 ACR/ARHP Annual Meeting

    The Value of Carotid Ultrasound in Cardiovascular Risk Stratification in Patients with Psoriatic Disease

    Curtis Sobchak1, Shadi Akhtari2, Paula Harvey2, Dafna D Gladman3, Vinod Chandran4, Richard J. Cook5 and Lihi Eder6, 1Faculty of Medicine, University of Toronto, Toronto, ON, Canada, 2Cardiology, Women's College Hospital, University of Toronto, Toronto, ON, Canada, 3Department of Medicine, Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Krembil Research Institute & University of Toronto, Toronto, ON, Canada, 5Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, 6Women's College Research Institute, University of Toronto, Women's College Hospital, Toronto, ON, Canada

    Background/Purpose: Patients with psoriatic disease (PsD) are at a high risk of developing cardiovascular events (CVE). The performance of clinical algorithms for cardiovascular risk stratification,…
  • Abstract Number: 1609 • 2018 ACR/ARHP Annual Meeting

    The Incidence Rate of Spondyloarthritis in Slovenia

    Natasa Potocnik Pucelj1, Alojzija Hočevar1, Rok Jese1, Ziga Rotar2 and Matija Tomšič3, 1Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 2BioRx.si, Ljubljana, Slovenia, Ljubljana, Slovenia, 3Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

    Background/Purpose: Spondyloarthritides (SpA) are heterogeneous group of inflammatory diseases, affecting both, axial and peripheral skeleton. Incidence studies in SpA are sparse. There is no data…
  • Abstract Number: 1610 • 2018 ACR/ARHP Annual Meeting

    Incremental Benefits to Quality of Life Associated with Achieving Higher Levels of American College of Rheumatology Response and Skin Clearance in Patients with Psoriatic Arthritis

    Josef S. Smolen1, David Shrom2, Chen-Yen Lin2, Julie Birt2, Georg Schett3 and Alice B Gottlieb4, 1Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria, 2Eli Lilly and Company, Indianapolis, IN, 3Medical Clinic 3, Friedrich-Alexander University, Erlangen-Nuremberg, Germany, 4Department of Dermatology, New York Medical College, New York, NY

    Background/Purpose: PsA is a chronic inflammatory disease associated with psoriasis. For optimal quality of life (QoL) improvements, all PsA symptoms should be managed. We examine…
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