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  • Abstract Number: 2474 • 2019 ACR/ARP Annual Meeting

    Impact of Multidomain Disease Presentations on Overall Disease Burden Among Patients with Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Alexis Ogdie1, Peter Hur 2, Mei Liu 3, Sabrina Rebello 3, Robert McLean 3, Blessing Dube 3, Meghan Glynn 4 and Philip Mease 5, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Corrona, LLC, Waltham, MA, 4Corrona, LLC, Waltham, 5Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic inflammatory disease with heterogeneous presentations that may involve peripheral arthritis, axial disease, enthesitis, dactylitis, and psoriatic skin and…
  • Abstract Number: 2475 • 2019 ACR/ARP Annual Meeting

    Prevalence of Disease Domain Presentations Among Patients with Psoriatic Arthritis: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Alexis Ogdie1, Peter Hur 2, Mei Liu 3, Sabrina Rebello 3, Robert McLean 3, Blessing Dube 3, Meghan Glynn 4 and Philip Mease 5, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3Corrona, LLC, Waltham, MA, 4Corrona, LLC, Waltham, 5Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease of the skin and musculoskeletal system. Six key domains of PsA have been identified to…
  • Abstract Number: 2476 • 2019 ACR/ARP Annual Meeting

    Side Effects of Methotrexate and TNFi: Differences in Tolerability Among Patients with PsA and RA

    Alexis Ogdie1, Ervant Maksabedian 2, Bradley Stolshek 2, Yomei Shaw 3 and Kaleb Michaud 4, 1University of Pennsylvania, Philadelphia, PA, 2Amgen Inc., Thousand Oaks, CA, 3FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, 4FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS

    Background/Purpose: Methotrexate (MTX) is generally well tolerated in rheumatoid arthritis (RA) but little is known about the tolerability of MTX in psoriatic arthritis (PsA).  One…
  • Abstract Number: 2477 • 2019 ACR/ARP Annual Meeting

    Burden of Disease at Treatment Initiation Among Biologic-Naïve Patients with Oligoarticular versus Polyarticular Psoriatic Arthritis in the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Alexis Ogdie1, Mei Liu 2, Meghan Glynn 3, Kelechi Emeanuru 2, Leslie Harrold 4, Sven Richter 5, Benoit Guerette 5 and Philip Mease 6, 1Department of Medicine and Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4Corrona, LLC and University of Massachusetts Medical School, Worcester, MA, 5Celgene Corporation, Summit, 6Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Oligoarticular PsA accounts for ≈50% of PsA worldwide, but only a paucity of data describes disease burden among these patients. The Corrona PsA/SpA Registry,…
  • Abstract Number: 2478 • 2019 ACR/ARP Annual Meeting

    Enthesitis Frequency and Treatment Patterns in Patients with Psoriatic Arthritis in Europe and Japan

    Daniel Aletaha1, Patrick Zueger 2, Naijun Chen 2 and Nicola Booth 3, 1Medical University of Vienna, Vienna, Austria, 2AbbVie Inc., North Chicago, IL, 3Adelphi Real World, Bollington, United Kingdom

    Background/Purpose: Enthesitis, a symptom commonly associated with psoriatic arthritis (PsA), negatively affects quality of life. Although enthesitis is routinely reported in randomized clinical trials of…
  • Abstract Number: 2479 • 2019 ACR/ARP Annual Meeting

    Unmet Treatment Needs in Patients with Psoriatic Arthritis

    Daniel Aletaha1, Mihalina Georgallis 2, Matthew Wallace 2, Patrick Zueger 3 and Ruth Zeidman 2, 1Medical University of Vienna, Vienna, Austria, 2Covance Market Access & Phase IV Solutions, London, United Kingdom, 3AbbVie Inc., North Chicago

    Background/Purpose: Despite significant advances in the treatment of psoriatic arthritis (PsA), disease control and remission remain a challenge. Research characterizing residual disease burden with current…
  • Abstract Number: 2480 • 2019 ACR/ARP Annual Meeting

    Opioid Use Surrounding Diagnosis of Inflammatory Arthritis

    Anna Sheahan1, Victor Sloan 1, Jeffrey Stark 2 and Robert Suruki 1, 1UCB Pharma, Raleigh, NC, 2UCB Pharma, Smyrna, GA

    Background/Purpose: Although treatment of inflammatory arthritis (IA) has improved, opioid use among patients remains common. A study from Finland showed increases in opioid use leading…
  • Abstract Number: 2481 • 2019 ACR/ARP Annual Meeting

    Uveitis in 320 Patients with Psoriatic Arthritis. Epidemiology, Clinical Features and Biological Treatment: Study from a Single University Center

    Iñigo Gonzalez-Mazon1, Lara Sanchez-Bilbao 2, Natalia Palmou-Fontana 1, DAVID MARTINEZ-LOPEZ 3, Mónica Calderón-Goercke 4, DIANA PRIETO- PENA 1, Susana Armesto-Alonso 3, Miguel A Gonzalez-Gay 2 and Ricardo Blanco 2, 1Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, 2Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 4Hospital Marqués de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Uveitis is an extra articular manifestation of psoriatic arthritis (PsA). Uveitis may be more chronic Biological therapy, especially monoclonal TNF inhibitors, are useful to…
  • Abstract Number: 2482 • 2019 ACR/ARP Annual Meeting

    Differences and Similarities According to Gender in Patients with Psoriatic Arthritis Initiating Biological Therapy

    Diego Benavent1, Chamaida Plasencia 2, Victoria Navarro-Compán 3, Laura Nuño 4, Irene Monjo 5, Carolina Tornero 6 and Alejandro Balsa 7, 1Hospital Universitario La Paz, Madrid, Spain, 2Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain, 3University Hospital La Paz, IdiPaz, Madrid, Spain, 4Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, Madrid, Spain, 5FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, 6Rheumatology Department. La Paz University Hospital., Madrid, 7Hospital Universitario La Paz, Madrid

    Background/Purpose: Growing evidence has pointed gender as a key variable influencing clinical response to biological drugs in psoriatic arthritis(PsA). Although the reasons remain unclear, it…
  • Abstract Number: 2483 • 2019 ACR/ARP Annual Meeting

    Comparison Between Composite Activity Indices to Assess Clinical Response to Biological Therapy in Patients with Psoriatic Arthritis

    Diego Benavent1, Chamaida Plasencia 2, Victoria Navarro-Compán 3, Diana Peiteado 4, Laura Nuño 5, Irene Monjo 6, Elisa Fernández 7 and Alejandro Balsa 2, 1Hospital Universitario La Paz, Madrid, Spain, 2Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain, 3University Hospital La Paz, IdiPaz, Madrid, Spain, 4Hospital Universitario La Paz, Madrid, 5Immuno-Rheumatology research group , Institute for Health Research (IdiPAZ), Madrid, Spain, MADRID, Spain, 6FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, 7Rheumatology Department, La Paz University Hospital, Madrid, Madrid, Spain

    Background/Purpose: Assessment of the disease in psoriatic arthritis (PsA) remains a clinical challenge. Hence, there is no agreement on which index best correlates with the…
  • Abstract Number: 2484 • 2019 ACR/ARP Annual Meeting

    Gender Influence on Treatment Effectiveness in Psoriatic Arthritis

    Diego Benavent1, Chamaida Plasencia 2, Victoria Navarro-Compán 3, Diana Peiteado 4, Alejandro Villalba 5, Laura Nuño 6, Elisa Fernández 7 and Alejandro Balsa 2, 1Hospital Universitario La Paz, Madrid, Spain, 2Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain, 3University Hospital La Paz, IdiPaz, Madrid, Spain, 4Hospital Universitario La Paz, Madrid, 5FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, 6Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, Madrid, Spain, 7Rheumatology Department, La Paz University Hospital, Madrid, Madrid, Spain

    Background/Purpose: Gender has been lately suggested as influential in the response to treatment with biological drugs in spondyloarthritis. However, data about the association between gender…
  • Abstract Number: 2485 • 2019 ACR/ARP Annual Meeting

    Red Cell Distribution Width Positively Correlates with Atherosclerotic Cardiovascular Disease Risk Score in Psoriatic Arthritis and Decreases with BDMARD Therapy

    Angela Gupta1, Sofi Damjanovska 2, David Zidar 3, Donald Anthony 4 and Maya Mattar 3, 1Case Western Reserve University, Cleveland, 2Case Western Reserve University, Cleveland Heights, OH, 3Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 4Case Western Reserve University, Cleveland, OH

    Background/Purpose: Red blood cell distribution width (RDW) is a parameter that measures variation in red blood cell size and volume. It is elevated when there…
  • Abstract Number: 2486 • 2019 ACR/ARP Annual Meeting

    Evaluation of Clinical and Functional Parameters by Joint Involvement and Remission in Psoriatic Arthritis

    Halise Hande Gezer1, Mehmet Tuncay Duruoz 2, Kemal Nas 3, Erkan Kilic 4, Betul Sargin 5, Sevtap Acer Kasman 2, Hakan Alkan 6, Nilay Sahin 7, Gizem Cengiz 8, Nihan Cuzdan 9, Ilknur Albayrak Gezer 10, Dilek Keskin 11, Cevriye Mulkoglu 12, Hatice Resorlu 13, Ismihan Sunar 14, Ajda Bal 15, Okan Kucukakkas 16, Ozan Volkan Yurdakul 16, Meltem Alkan Melikoglu 17, Yildiray Aydin 3, Fikriye Figen Ayhan 18, Hatice Bodur 19, Mustafa Calis 8, Erhan Capkin 20, Gul Devrimsel 21, Kevser Gök 22, Sami Hizmetli 23, Ayhan Kamanli 3, Yasar Keskin 16, Hilal Kocabas 24, Oznur Kutluk 25, Nesrin Sen 26, Omer Faruk Sendur 27, Ibrahim Tekeoglu 3, Sena Tolu 28, Murat Toprak 29 and Tiraje Tuncer 25, 1Marmara University School of Medicine, PMR Department, Rheumatology Division, İstanbul, Istanbul, Turkey, 2Marmara University School of Medicine, PMR Department, Rheumatology Division, İstanbul, Turkey, 3Sakarya University School of Medicine, PMR Department, Rheumatology and Immunology Division, Sakarya, Turkey, 4Afyonkarahisar State Hospital, Afyonkarahisar, Turkey, 5Adnan Menderes University School of Medicine, PMR Department, Rheumatology Division, Aydın, Turkey, 6Pamukkale University School of Medicine, PMR Department, Rheumatology Division, Denizli, Turkey, 7Balıkesir University School of Medicine, PMR Department, Balıkesir, Turkey, 8Erciyes University School of Medicine, PMR Department, Rheumatology Division, Kayseri, Turkey, 9Şanlıurfa Training and Research Hospital, Rheumatology Clinic, Şanlıurfa, Turkey, 10Selçuk University School of Medicine, PMR Department, Konya, Turkey, 11Kırıkkale University School of Medicine, PMR Department, Kırıkkale, Turkey, 12Ankara Training and Research Hospital, PMR Clinic, Ankara, Turkey, 13Çanakkale Onsekiz Mart University School of Medicine, PMR Department, Çanakkale, Turkey, 14Ankara Unversity School of Medicine, Physical Medicine and Rehabilitation, Rheumatology Department, Ankara, Turkey, 15Dışkapı Yıldırım Beyazıt Training and Research Hospital, PMR Clinic, Ankara, Turkey, 16Bezmialem Vakıf University School of Medicine, PMR Department, İstanbul, Turkey, 17Atatürk University School of Medicine, PMR Department, Rheumatology Division, Erzurum, Turkey, 18Uşak University School of Health Sciences, PMR Department, Uşak, Turkey, 19Yıldırım Beyazıt University School of Medicine, PMR Department, Ankara, Turkey, 20Karadeniz Teknik University School of Medicine, PMR Department, Trabzon, Turkey, 21Recep Tayyip Erdoğan University School of Medicine, PMR Department, Riza, Turkey, 22Numune Training and Research Hospital, Rheumatology Clinic, Ankara, Turkey, 23Cumhuriyet University School of Medicine, PMR Department, Rheumatology Division, Sivas, Turkey, 24Necmettin Erbakan University Meram School of Medicine, PMR Department, Rheumatology Division, Konya, Turkey, 25Akdeniz University School of Medicine, PMR Department, Rheumatology Division, Antalya, Turkey, 26Kartal Dr. Lütfi Kırdar Training and Research Hospital, Rheumatology Clinic, İstanbul, Turkey, 27Adnan Menderes University School of Medicine, PMR Department, Aydın, Turkey, 28Medipol University School of Medicine, PMR Department, İstanbul, Turkey, 29Yüzüncü Yıl University School of Medicine, PMR Department, Van, Turkey

    Background/Purpose: Disease activity of psoriatic arthritis (PsA) is affected by many parameters including joint, spinal and skin involvement, enthesitis, dactylitis and pain. According to disease…
  • Abstract Number: 2487 • 2019 ACR/ARP Annual Meeting

    Identification of Circulating MicroRNA Signatures in Patients with Psoriasis and Psoriatic Arthritis to Develop Novel Strategies for Early Diagnosis of a Bone and Joint Involvement

    Judith Haschka1, David Simon 2, Sara Bayat 3, Arnd Kleyer 3, Eleni Kampylafka 3, Axel Hueber 4, Christian Muschitz 5, Susanna Skalicky 6, Matthias Hackl 6, Heinrich Resch 1, Georg Schett 7, Roland Kocijan 8 and Jürgen Rech 9, 1Karl Landsteiner Institute for Gastroenterology and Rheumatology, St. Vincent Hospital Vienna, II Medical Department, Vienna, Austria, 2Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, 3Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, 4Sozialstiftung Bamberg, Klinikum Bamberg, Section Rheumatology, Bamberg, Germany, Bamberg, Germany, 5St. Vincent Hospital Vienna, II Medical Department, VINFORCE Study Group, Vienna, Austria, 6TAmiRNA GmbH, Vienna, Austria, Vienna, Austria, 7Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, 8Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria, 9Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: MicroRNAs (miRNAs) are small non-coding RNAs which are regulating physiologic and pathological processes. In numerous diseases specific miRNA signatures have been identified and can…
  • Abstract Number: 2488 • 2019 ACR/ARP Annual Meeting

    MDA Versus DAPSA: Applicability in a Real World

    rafaela Gonçalves1, Lays Martins 2, henrique mariz 1, marina brito 3, georgia pereira 3, andrea dantas 3 and Angela Duarte 2, 1clinical hospital of federal university of pernambuco, recife, Pernambuco, Brazil, 2Universidade Federal de Pernambuco, Recife, Brazil, 3clinical hospital of federal university of pernambuco, recife, Brazil

    Background/Purpose: Background/Purpose: Psoriatic arthritis (PsA) is a progressive, chronic, and potentially irreversible inflammatory disorder. Systematic clinical follow-up of PsA patients is necessary to maintain and…
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