Abstracts Archive - Page 1101 of 2425 - ACR Meeting Abstracts

Abstract Number: 1446 • 2018 ACR/ARHP Annual Meeting
The Optimal Joint Set for Ultrasound Assessment of Synovitis in RA: Results from the Rasch Measurement Model
Elizabeth M.A. Hensor^1,2, Alan Tennant³, Philip G. Conaghan^1,2, Hilde B Hammer⁴, Richard J. Wakefield^1,2 and Maria Antonietta D'Agostino^1,5, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Leeds, United Kingdom, ³Swiss Paraplegic Research, Nottwil, Switzerland, ⁴Rheumatology, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵Rheumatology, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, France
Background/Purpose: The recently introduced composite OMERACT-EULAR power Doppler (PD)/grey scale (GS) ultrasound (PDUS) scoring system for RA with a proposed 18 joint set was developed…
Abstract Number: 1447 • 2018 ACR/ARHP Annual Meeting
Decreased Lymphatic Drainage in the Hands of Flaring RA Patients As Measured By Indocyanine Green Clearance Via Real Time Near Infrared Imaging
Richard Bell¹, Homaira Rahimi², Alicia Lieberman³, Ronald Wood⁴, Edward Schwarz⁵ and Christopher T. Ritchlin⁶, ¹Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ²Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY, ³Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁴University of Rochester, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY, ⁶Division of Allergy/Immunology and Rheumatology and Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester Medical School, Rochester, New York, USA, Rochester, NY
Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis established abnormal lymphatic vessel (LV) function during arthritic…
Abstract Number: 1448 • 2018 ACR/ARHP Annual Meeting
Clinical Impact of Articular Ultrasound in Diagnosis and Follow-up of Patients with Polyarthritis
Justine Lafleur-Careau¹, François Taschereau¹, Artur J de Brum-Fernandes², Alessandra Bruns³, Gilles Boire⁴ and Ariel Masetto⁵, ¹Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ²Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ³Rhumatologie, Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology Division, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁵Centre Hospitalier Universitaire de Sherbrooke (CHUS), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, AB, Canada
Background/Purpose: It is well established in the literature that musculoskeletal ultrasound (MSUS) is more sensitive than clinical examination in the detection of synovitis. MSUS can…
Abstract Number: 1449 • 2018 ACR/ARHP Annual Meeting
Microwave Radiometry As a Novel Additional Method for Rheumatoid Arthritis Disease Activity Assessment: A Prospective Single-Center Study
Katerina Laskari¹, George Pentazos¹, George Konstantonis¹, Maria Tektonidou¹, Elias Siores² and Petros Sfikakis¹, ¹Rheumatology Unit, 1st Dept. of Propaedeutic Internal Medicine, Joint Academic Rheumatology Program, Athens University Medical School, Athens, Greece, ²Institute of Materials Research and Innovation, University of Bolton, Bolton, United Kingdom
Background/Purpose: Microwave Radiometry (MR) is an easy-to perform, rapid, non-invasive method detecting in-depth tissue temperature that may be useful for joint inflammation assessment in RA…
Abstract Number: 1450 • 2018 ACR/ARHP Annual Meeting
Clinical Radiology Reports Are Unreliable for Assessment of Radiographic Structural Progression in US Veterans with Rheumatoid Arthritis Initiating Tumor Necrosis Factor Inhibitor Therapy
Kevin R. Lammert¹, Alan R. Erickson², Brian C. Sauer¹ and Grant W. Cannon¹, ¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Rheumatologists rely on hand radiograph findings including bone erosions (BE) and joint space narrowing (JSN) to make treatment decisions for patients with rheumatoid arthritis…
Abstract Number: 1451 • 2018 ACR/ARHP Annual Meeting
The Value of Adding MRI to a Clinical Treat-to-Target Strategy in Rheumatoid Arthritis Patients in Clinical Remission: Clinical and Radiographic Outcomes from the Imagine-RA Randomized Controlled Trial
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen², Bo Jannik Ejbjerg³, Merete Lund Hetland¹, Daniel Glinatsi⁴, Lykke Ørnbjerg¹, Jakob M. Møller⁵, Mikael Boesen⁶, Robin Christensen⁷, Kristian Stengaard-Pedersen⁸, Ole Rintek Madsen⁹, Bente Jensen¹⁰, Jan Alexander Villadsen¹¹, Ellen-Margrethe Hauge⁸, Philip Bennett¹², Oliver Hendricks², Karsten Asmussen¹³, Marcin Ryszard Kowalski¹⁴, Hanne Lindegaard¹⁵, Sabrina Mai Nielsen⁷, Henning Bliddal¹⁶, Niels Steen Krogh¹⁷, Torkell Ellingsen¹⁵, Agente Nielsen¹⁸, Lone Balding⁵, Anne Grethe Jurik¹⁹, Henrik S Thomsen⁵ and Mikkel Østergaard²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ²King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, ⁴Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ⁵Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ⁷Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, ⁸Department of Rheumatology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus, Denmark, ⁹Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Hellerup, Denmark, ¹⁰Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark, Copenhagen, Denmark, ¹¹Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, ¹²Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Copenhagen, Denmark, ¹³Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁴Department of Rheumatology, Sygehus Vendsyssel, Hjørring, Hjørring, Denmark, ¹⁵Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁶The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁷The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, ¹⁹Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ²⁰Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Targeting MRI remission in rheumatoid arthritis (RA) patients in clinical remission may improve clinical outcome and halt joint damage progression. The purpose of the…
Abstract Number: 1452 • 2018 ACR/ARHP Annual Meeting
Combination of Ultrasound Power Doppler-Verified Synovitis and Seropositivity Accurately Identifies Patients with Early Rheumatoid Arthritis
Shinya Kawashiri¹, Keita Fujikawa², Ayako Nishino¹, Ayuko Takatani¹, Toshimasa Shimizu¹, Masataka Umeda¹, Shoichi Fukui¹, Takashi Igawa¹, Tomohiro Koga¹, Naoki Iwamoto¹, Kunihiro Ichinose¹, Mami Tamai¹, Hideki Nakamura¹, Tomoki Origuchi³ and Atsushi Kawakami¹, ¹Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Japan Community Health care Organization Isahaya General Hospital, Nagasaki, Japan, ³Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
Background/Purpose: We conducted this retrospective study to determine objective and comprehensive diagnostic criteria for early rheumatoid arthritis (RA) that are based on ultrasound (US) and…
Abstract Number: 1453 • 2018 ACR/ARHP Annual Meeting
Correlation between Clinical and Ultrasonographic Remission? the Effect of Non-Inflammatory Patient-Based Factors on Different Remission Definitions
Ummugulsum Gazel¹, Sibel Yilmaz Oner², Gulsen Ozen³, Yasemin Yalçınkaya³, Pamir Atagunduz³, Haner Direskeneli³ and Nevsun Inanc³, ¹Rheumatology, Marmara University faculty of Medicine, Istanbul, Turkey, ²Rheumatology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey, ³Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: In this study, we aimed to investigate the concordance of ultrasonographic remission with other remission criteria and to show the influence of non-inflammatory patient-induced…
Abstract Number: 1454 • 2018 ACR/ARHP Annual Meeting
Levels of 14-3-3eta Are an Independent Predictor of Long-Term Radiographic Erosive Progression and of Short-Term Rapid Radiographic Erosive Progression in Patients with Inflammatory Polyarthritis
Gilles Boire¹, Nathalie Carrier², Artur J deBrum Fernandes³, Patrick Liang¹, Ariel Masetto⁴, Sophie Roux⁴, Norma K Biln⁵, Yuan Gui⁵, Jane Savill⁵, Sara Michienzi⁵ and Walter P. Maksymowych⁶, ¹Rheumatology Division, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ²Centre intégré universitaire de santé et de services sociaux de l'Estrie -Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada, ³Medicine, Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁴Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁵Augurex Life Sciences Corp, Vancouver, BC, Canada, ⁶Department of Medicine, CaRE Arthritis and University of Alberta, Edmonton, Canada, Edmonton, AB, Canada
Background/Purpose: Our objective is to examine the additional contribution of 14-3-3η levels to known predictors of radiographic progression in inflammatory polyarthritis, both over several years…
Abstract Number: 1455 • 2018 ACR/ARHP Annual Meeting
Development of a Predictive Model of Radiological Damage in Patients with Rheumatoid Arthritis Based on Artificial Intelligence
Jose M Lezcano¹, José Ivorra-Cortes², Alfredo Madrid³, Raquel Lopez-Mejías⁴, Javier Martin⁵, Benjamín Fernández-Gutiérrez⁶, Miguel Angel González-Gay⁷, Alejandro Balsa⁸, Isidoro Gonzalez-Alvaro⁹, Fernando Salazar¹⁰, Lydia A Alcazar¹¹ and Luis Rodriguez-Rodriguez¹¹, ¹Helix BioS CEO, Madrid, Spain, ²Rheumatology, University Hospital la Fe, Valencia, Spain, ³Rheumatology Department, and Instituto de Investigación Sanitaria (IdISSC), Hospital Clínico San Carlos, Madrid, Spain, ⁴Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, Santander, Spain, ⁵Instituto de Parasitología y Biomedicina López Neyra, Granada, Spain, ⁶Department of Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, ⁷School of Medicine, University of Cantabria, Santander, Spain, Santander, Spain, ⁸Rheumatology Department, Hospital Universitario La Paz, IdiPAZ, Madrid, Spain, ⁹Rheumatology Department, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, ¹⁰International Centre for Numerical Methods in Engineering (CIMNE), Madrid, Spain, ¹¹Rheumatology Department and Heath Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased mortality and disability. Although different factors have been associated with prognosis, it is…
Abstract Number: 1456 • 2018 ACR/ARHP Annual Meeting
Neutrophil Activation Is Associated with Disease Activity and Predicts Development of Erosive Disease and Extra Articular Manifestations in Rheumatoid Arthritis
Mary Bach^1,2, Tiffany Pan³, J. Lee Nelson^3,4 and Christian Lood⁵, ¹VA Puget Sound Health Care System, Seattle, WA, ²Division of Rheumatology, University of Washington, Seattle, WA, ³Fred Hutchinson Cancer Research Center, Seattle, WA, ⁴Division of Rheumatology, University of Washington, SEATTLE, WA, ⁵Department of Medicine, Division of Rheumatology, University of Washington, Seattle, WA
Background/Purpose: Neutrophil activation is associated with inflammation and autoimmunity, including rheumatoid arthritis (RA), where neutrophil infiltration into joints participates in tissue destruction and development of…
Abstract Number: 1457 • 2018 ACR/ARHP Annual Meeting
Association between Disease Activity and Radiographic Progression in the Current Treat-to-Target Paradigm of Rheumatoid Arthritis: Real World Data from the Dutch Rheumatoid Arthritis Monitoring (DREAM) Registry
Peter M. ten Klooster^1,2, Laura M.M. Steunebrink³, Letty Versteeg⁴, Inmaculada de la Torre⁵, Francesco de Leonardis⁶, Walid Fakhouri⁶, Liliana Zaremba-Pechmann⁶ and Mart van de Laar^1,3, ¹Transparency in Healthcare B.V., Hengelo, Netherlands, ²Arthritis Centre Twente, University of Twente, Enschede, Netherlands, ³Arthritis Centre Twente, Medisch Spectrum Twente, Enschede, Netherlands, ⁴Rheumatology, Arthritis Centre Twente, Medisch Spectrum Twente, Enschede, Netherlands, ⁵Eli Lilly and Company, Madrid, Spain, ⁶Eli Lilly and Company, Indianapolis, IN
Background/Purpose: Recent studies suggested a disconnect between disease activity and radiographic damage in rheumatoid arthritis (RA) patients treated with more aggressive treatment (1). Therefore, the…
Abstract Number: 1458 • 2018 ACR/ARHP Annual Meeting
Impact of the Joint Presence of Erosions and ACPA on Rheumatoid Arthritis Disease Activity over Time: Results from the Meteor Registry
Sytske Anne Bergstra¹, Maura Couto², Nimmisha Govind³, Arvind Chopra⁴, Karen Salomon-Escoto⁵, Elizabeth Murphy⁶, Tom W.J. Huizinga¹ and Cornelia F. Allaart¹, ¹Department of Rheumatology, LUMC, Leiden, Netherlands, ²Hospital Sao Teotónio, Viseu, Portugal, Viseu, Portugal, ³University of the Witwatersrand, Johannesburg, South Africa, ⁴Center for Rheumatic Diseases, Pune, India, ⁵University of Massachusetts Medical School, Rheumatology Center, UMass Memorial Medical Center, Worcester, MA, ⁶University Hospital Wishaw, Scotland, Wishaw, United Kingdom
Background/Purpose: Despite efforts to predict treatment response, treatment of rheumatoid arthritis (RA) patients remains mostly a case of trial and error. Previous research, mostly in…
Abstract Number: 1459 • 2018 ACR/ARHP Annual Meeting
Bone Erosion Volume Changes Measured By HR-pQCT at 3-Months after Initiation of Anti-TNF Treatment Predicted Erosion Volume Changes at 1-Year in RA
Tomohiro Shimizu¹, Kenji Mamoto¹, Matthew Tanaka¹, Andrew J Burghardt², Thomas Link¹, Jonathan Graf³, John B. Imboden Jr.³ and Xiaojuan Li¹, ¹Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, University of California, San Francisco, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA
Background/Purpose: Bone erosions and joint space narrowing (JSN) are significant aspects of structural damage in rheumatoid arthritis. High resolution peripheral quantitative computed tomography (HR-pQCT) allows…
Abstract Number: 1460 • 2018 ACR/ARHP Annual Meeting
Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis
Brian J. Andonian¹, Ching-Heng Chou², Virginia B. Kraus², William E. Kraus³ and Kim M. Huffman⁴, ¹Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC, ²Duke Molecular Physiology Institute, Duke University, Durham, NC, ³Medicine, Duke University, Durham, NC, ⁴School of Medicine, Division of Rheumatology, Immunology and Molecular Physiology and Durham VA Medical Center, Duke University, Durham, NC
Background/Purpose: In rheumatoid arthritis (RA), sarcopenic obesity is associated with significant cardiometabolic disease and mortality. Biomarkers of disease activity in RA and obesity are complicated…

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