ACR Meeting Abstracts

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  • Abstract Number: 1131 • 2018 ACR/ARHP Annual Meeting

    The Prevalence and Incidence of Gout, Its Associated Comorbidities and Treatment Pattern: An Epidemiological Study from Germany

    Uta Kiltz1, Fernando Perez-Ruiz2, Till Uhlig3, Tim L. Jansen4, Ravichandra Karra Gurunath5, Niklas Schmedt6, Wolfgang Galetzka6, Gudula Petersen5, Tonio Schoenfelder7 and Anne-Kathrin Tausche8, 1Rheumazentrum Ruhrgebiet, Herne, and Ruhr-University, Bochum, Herne, Germany, 2BioCruces Health Research Institute, Barakaldo, Spain, 3University of Oslo, Oslo, Norway, 4Rheumatology, VieCuri Medical Centre, Venlo, Netherlands, 5Grünenthal GmbH, Aachen, Germany, 6InGef – Institute for Applied Health Research, Berlin, Germany, 7Institute for Applied Health Services Research, Berlin, Germany, 8Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden, Germany

    Background/Purpose: The most common type of inflammatory arthritis in Germany is gout, however the last epidemiological study was done a decade ago (Annemanns, 2007). This…
  • Abstract Number: 1132 • 2018 ACR/ARHP Annual Meeting

    Diet Modification for Gout Patients: Effects on Gout Attacks and Risk Factors for Metabolic Syndrome

    Michelle DiFiore1, Maida Wong2 and Juliana Chang3, 1Internal Medicine, University of California, Irvine, School of Medicine, Orange, CA, 2Division of Rheumatology, Tibor Rubin Veterans Affairs Medical Center Long Beach, Long Beach, CA, 3UC Irvine Medical Center, Orange, CA

    Background/Purpose: Gout affects 8 million individuals in the US and is prevalent among patients with metabolic syndrome. Although there are many medications to control gout…
  • Abstract Number: 1133 • 2018 ACR/ARHP Annual Meeting

    Factors for Opioids Use in the Early Treatment Options for the Knee Osteoarthritis Patients

    Soo-Kyung Cho1, Seongmi Choi2, Seul Gi Im2, Hyoungyoung Kim1, Sun-Young Jung3, Eun Jin Jang4 and Yoon-Kyoung Sung5, 1Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), 2Statistics, Kyungpook National University, Daegu, Korea, Republic of (South), 3College of Pharmacy, Chung-Ang University, Seoul, Korea, Republic of (South), 4Information Statistics, Andong National University, Andong-si, Korea, Republic of (South), 5Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South)

    Background/Purpose: Current guidelines for osteoarthritis (OA) treatment recommend a range of nonpharmacological and pharmacological interventions to alleviate pain, improve function and quality of life. Most…
  • Abstract Number: 1134 • 2018 ACR/ARHP Annual Meeting

    Some Is Better Than None: Minimum Physical Activity Threshold to Prevent Disability in Older Adults with Lower Extremity Joint Symptoms

    Dorothy D. Dunlop1, Jing Song1, Jennifer M. Hootman2, Julia (Jungwha) Lee3, Michael C. Nevitt4, Leena Sharma5, Pamela Semanik6, Charles B. Eaton7, C. Kent Kwoh8, Marc C. Hochberg9, Rebecca D. Jackson10 and Rowland W. Chang11, 1Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, 3Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6College of Nursing, Rush University, Chicago, IL, 7Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, 8Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, 9University of Maryland School of Medicine, Baltimore, MD, 10Ohio State University, Columbus, OH, 11Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: This study evaluated physical activity and sedentary times to identify an evidence-based threshold related to remaining free of disability over 4 years among adults…
  • Abstract Number: 1135 • 2018 ACR/ARHP Annual Meeting

    Genome-Wide Meta-Analysis Identified Two Novel Variants Associated with Hallux Valgus

    Liubov Arbeeva1, Braxton Mitchell2, Rebecca D. Jackson3, Michelle S. Yau4, Kathleen Ryan5, Yvonne M. Golightly6, Marian T. Hannan7, Amanda Nelson8, Joanne M. Jordan9 and Marc C. Hochberg2, 1TARC, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2School of Medicine, University of Maryland, Baltimore, MD, 3Ohio State University, Columbus, OH, 4Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, 5University of Maryland, Baltimore, MD, 6Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 7Institute for Aging Research, Hebrew SeniorLife & Harvard Medical School, Boston, MA, 8UNC School of Medicine, Chapel Hill, NC, 9Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Hallux valgus (HV) is a common foot disorder that is highly heritable. A genome-wide association study (GWAS) conducted in 4,409 Caucasians from the Framingham…
  • Abstract Number: 1136 • 2018 ACR/ARHP Annual Meeting

    Association of Mitochondrial DNA Haplotypes with Symptomatic Hand and Thumb Based Osteoarthritis and Hand OA Progression

    Charles Eaton1, Mary Roberts2, Jeffrey B. Driban3, Ida Kristin Haugen4, Lena Franziska Schaefer5, Bing Lu6, Rebecca D. Jackson7, Marc C. Hochberg8, C. Kent Kwoh9, Francisco J Blanco10 and Timothy E. McAlindon11, 1Family Medicine and Epidemiology, Warren Alpert Medical School, School of Public Health, Brown University, Providence, RI, 2Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, 3Rheumatology, Tufts Medical Center, BOSTON, MA, 4Diakonhjemmet Hospital, Oslo, Norway, 5Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, 6Division of Rheumatology, Immunology and Allergy, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 7Ohio State University, Columbus, OH, 8School of Medicine, University of Maryland, Baltimore, MD, 9Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, 10Rheumatology Division, ProteoRed, PRB2-ISCIII. INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, 11Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Hand osteoarthritis (OA) can be a painful, disabling condition, with an increased prevalence in women, the elderly, and has a strong genetic component (hereditability…
  • Abstract Number: 1137 • 2018 ACR/ARHP Annual Meeting

    Prediction Models for Poor Function Outcomes over 10 Years in Persons at High Risk for Knee Osteoarthritis

    Leena Sharma1, Orit Almagor1, Alison H. Chang1, C. Kent Kwoh2, Michael C. Nevitt3, Marc C. Hochberg4, Rebecca D. Jackson5, Charles B. Eaton6, Jane A. Cauley7, Julie Szymaszek8 and Joan S. Chmiel1, 1Northwestern University, Chicago, IL, 2University of Arizona, Tucson, AZ, 3UCSF, San Francisco, CA, 4University of Maryland School of Medicine, Baltimore, MD, 5Ohio State University, Columbus, OH, 6Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, 7University of Pittsburgh, PIttsburgh, PA, 8Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose:   Among persons at high risk for knee osteoarthritis (OA), identifying those who will have function decline is important; instituting prevention strategies in all…
  • Abstract Number: 1138 • 2018 ACR/ARHP Annual Meeting

    Public Health Impact of Physical Inactivity in the Knee OA Population in the US

    Elena Losina1, Genevieve S. Silva2, Karen C. Smith2, Jamie E. Collins3, David J. Hunter4, Swastina Shrestha2, Stephen P. Messier5, Edward H. Yelin6, Lisa Gale Suter7, A. David Paltiel8 and Jeffrey N. Katz9, 1Orthopedics, Brigham and Women's Hospital, BU School of Public Health and Harvard Medical School, Boston, MA, 2Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 3Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 4Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 5Department of Health and Exerc, Wake Forest University, Winston-Salem, NC, 6Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 7Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, 8Yale University, New Haven, CT, 9Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: The benefits of physical activity (PA) in persons with OA are well-documented: PA reduces OA pain, improves mental health, and reduces the risk of…
  • Abstract Number: 1139 • 2018 ACR/ARHP Annual Meeting

    Can Body Composition Explain the Sex Disparity in Risk of Osteoarthritis?

    Shanshan Li1, Tuhina Neogi2, Devyani Misra3, Ann Schwartz4, Michael C. Nevitt5, Cora E. Lewis6, James Torner7 and David T. Felson2, 1Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Cambridge, MA, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3School of Medicine, Boston University School of Medicine, Boston, MA, 4University of California San Francisco, San Francisco, CA, 5Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 6University of Alabama Birmingham, Birmingham, AL, 7University of Iowa, Iowa City, IA

    Background/Purpose: Obesity is a major risk factor for knee osteoarthritis (OA), but the mechanisms by which obesity confers OA risk remains unclear. There is a…
  • Abstract Number: 1140 • 2018 ACR/ARHP Annual Meeting

    Cause-Specific Mortality in Knee, Hip and Hand Osteoarthritis

    Aleksandra Turkiewicz, Aliasghar Kiadaliri and Martin Englund, Clinical Sciences Lund, Clinical Epidemiology Unit, Lund University, Lund, Sweden

    Background/Purpose: All-cause mortality in osteoarthritis (OA) is reported to be increased. However, the knowledge about cause-specific mortality in OA is still very limited. Thus, our…
  • Abstract Number: 1141 • 2018 ACR/ARHP Annual Meeting

    Trajectories of Extensive Sitting and Associated Predictors in Persons at High Risk for Knee Osteoarthritis

    Julia (Jungwha) Lee1, Alison H. Chang2, Orit Almagor2, Joan S. Chmiel3, Karen W. Hayes2, C. Kent Kwoh4 and Leena Sharma5, 1Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Medicine, Division of Rheumatology, University of Arizona School of Medicine, University of Arizona Arthritis Center, Tucson, AZ, 5Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose:  Too much sitting has been recognized as a major public health issue. However, it is unknown if distinctive patterns of extensive sitting over time…
  • Abstract Number: 1142 • 2018 ACR/ARHP Annual Meeting

    Trend of Lymphoma Incidence in US Veterans with Rheumatoid Arthritis Vs Osteoarthritis: 2002-2017

    Namrata Singh1, Yubo Gao2, Brice Beck3, Bryant R. England4, Grant W. Cannon5, Ted R. Mikuls6, Jeffrey R. Curtis7, Brian Link8, Charles Lynch9, Elizabeth Field10 and Mary Vaughan-Sarrazin2, 1Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, 2University of Iowa Hospitals and Clinics, Iowa City, IA, 3Internal Medicine, Iowa City VA Medical Center, Iowa City, IA, 4Rheumatology, VA Nebraska-Western Iowa Health Care System & University of Nebraska Medical Center, Omaha, NE, 5Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, 6Internal Medicine, Division of Rheumatology, VA Nebraska-Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, 7University of Alabama, Birmingham, AL, 8Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, 9Epidemiology, University of Iowa, Iowa City, IA, 10Iowa City VA, Iowa City, IA

    Background/Purpose: Past epidemiologic studies have consistently demonstrated a link between Rheumatoid Arthritis (RA) and lymphomas and have posited that high systemic inflammatory activity is a…
  • Abstract Number: 1143 • 2018 ACR/ARHP Annual Meeting

    Periodontal Disease Is Associated with an Increased Risk of Ankylosing Spondylitis: A Systematic Review and Meta-Analysis

    Patompong Ungprasert1, Karn Wijarnpreecha2 and Wisit Cheungpasitporn3, 1Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Internal medicine, Bassett medical center, cooperstown, NY, 3Medicine, University of Mississippi Medical center, Jackson, MS

    Periodontal Disease is Associated with an Increased Risk of Ankylosing Spondylitis: A Systematic Review and Meta-analysisAbstractBackground/Purpose: The association between periodontal disease and rheumatoid arthritis is…
  • Abstract Number: 1144 • 2018 ACR/ARHP Annual Meeting

    Risk of Osteoporotic Fractures in Patients with Rheumatoid Arthritis and End Stage Renal Disease. Findings from the Usrds Database

    Renee Peterkin-McCalman, Jennifer Waller, Brian Le, Alyce Oliver, Evan Manning, Stanley Nahman and Laura Carbone, Medical College of Georgia at Augusta University, Augusta, GA

    Background/Purpose: Rheumatoid arthritis (RA) and End Stage Renal Disease (ESRD) are independent risk factors for osteoporotic fractures. Approximately one percent of persons with ESRD have…
  • Abstract Number: 1145 • 2018 ACR/ARHP Annual Meeting

    Association of Niacin Intake with Osteoporosis. the Cardiovascular Health Study

    Brian Le1, Petra Bůžková2, Howard Fink3, John Robbins4, Mattie Raiford1, Carlos Isales1, James Shikany5, Steven Coughlin1 and Laura Carbone1, 1Medical College of Georgia at Augusta University, Augusta, GA, 2Washington University, Seattle, WA, 3Minneapolis VA Health Care System, Minneapolis, MN, 4University of California-Davis, Sacramento, CA, 5University of Alabama, Birmingham, AL

    Background/Purpose: Interest in niacin has increased in the setting of reports suggesting that niacin plays a role in diseases of aging, including Parkinson’s disease and…
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