Abstracts Archive - Page 1055 of 2425 - ACR Meeting Abstracts

Abstract Number: 756 • 2018 ACR/ARHP Annual Meeting
Peripheral Neutrophil CD64 Index Combined with Biomarkers Improves the Ability of Diagnosing Bacterial Infection in Patients with SLE
Min Feng¹, Zhaojun Liang², Xiangcong Zhao¹, Chong Gao³ and Jing Luo⁴, ¹The Second Hospital of Shanxi Medical University, Taiyuan, China, ²Division of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China, Taiyuan, China, ³Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, Cambridge, MA, ⁴the Second Hospital of Shanxi Medical University, Taiyuan, China
Background/Purpose: Patients with Systemic lupus erythematosus (SLE) are prone to bacterial infection owing to disease activity, abnormal immune function and long-term immunosuppressive therapy. Differentiating bacterial infection from…
Abstract Number: 757 • 2018 ACR/ARHP Annual Meeting
Urinary Galectin-3 Binding Protein As a Novel Biomarker of Renal Disease Activity in Lupus Nephritis
Huihua Ding¹, Cheng Ling², Roberto Bassi³, Shinji L Okitsu⁴, Julie A. DeMartino⁴ and Nan Shen¹, ¹Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China, ²Department of Rheumatology, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China, ³EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁴TIP Immunology, EMD Serono Research and Development Institute, Inc., Billerica, MA
Background/Purpose: Lupus nephritis (LN) is one of the most common and severe manifestations of systemic lupus erythematosus (SLE). This study investigates urinary galecting-3 binding protein…
Abstract Number: 758 • 2018 ACR/ARHP Annual Meeting
Cutaneous Lupus Erythematosus Patients with a Negative ANA Meeting Acr and/or SLICC Criteria for Systemic Lupus Erythematosus
Meera Tarazi¹, Carolyn Kushner², Rebecca Gaffney² and Victoria P. Werth³, ¹Department of Dermatology, University of Pennsylvania, Philadelphia, PA, ²Dermatology, University of Pennsylvania, Philadelphia, PA, ³Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Systemic lupus erythematosus (SLE) is a disorder that is heterogeneous and can be difficult to diagnose. One hallmark of the disease is the presence…
Abstract Number: 759 • 2018 ACR/ARHP Annual Meeting
Comparison of Length of Stay and Total Hospital Charges for Hospitalizations for Sepsis in Patients with Systemic Lupus Erythematosus: A Study of National Inpatient Sample Database 2010 to 2014
Karan Chugh¹, Shraddha Jatwani², Karan Jatwani³ and Jasleen Kaur⁴, ¹Division of Pulmonary, Critical Care & Sleep, Wayne State University/Detroit Medical Center, Detroit, MI, ²Department of Internal Medicine, Division of Rheumatology, Henry Ford Allegiance Health, Jackson, MI, ³Department of Internal Medicine, Mount Sinai West - St Luke’s Hospital, New York, NY, ⁴Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI
Background/Purpose: Sepsis is a systemic inflammatory response syndrome caused by an infection with at least one acute organ failure and is major public health concern.1…
Abstract Number: 760 • 2018 ACR/ARHP Annual Meeting
Diagnosing SLE Arthritis with Dynamic Diffuse Optical Spectroscopy
George Danias¹, Youngwan Kim², Alessandro Marone³, Kayla Neville¹, Andrea Frantz¹, Teja Kapoor⁴, Laura Geraldino-Pardilla¹, Ioannis Kymissis², Andreas Hielscher^2,3,5 and Anca Askanase¹, ¹Rheumatology, Columbia University Medical Center, New York, NY, ²Electrical Engineering, Columbia University, New York, NY, ³Biomedical Engineering, Columbia University, New York, NY, ⁴Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁵Radiology, Columbia University Medical Center, New York, NY
Background/Purpose: SLE arthritis is difficult to evaluate because of the sometimes-evanescent nature of the symptoms and limitations of physical exams and imaging studies. Dynamic diffuse…
Abstract Number: 761 • 2018 ACR/ARHP Annual Meeting
Protein/Creatinin Urinary Index Has Concordance with 24 Hour Urinary Proteinuria in Patients with Systemic Lupus Erythematosus
Eugenia Picco¹, Ricardo Vicente Juárez², Emilio Buschiazzo², Natalia Lili Cucchiaro³, Gustavo Rua⁴, Patricia Talocchino¹, Ivana Romina Rojas Tessel¹, Mariana Aciar³, Maria Veronica Lencina³ and Maria Elena Crespo Espindola⁵, ¹Hospital Señor del Milagro, Salta, Argentina, ²Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, ³Rheumatology, Hospital Señor del Milagro, Salta, Argentina, ⁴Biochemistry Section, Hospital Señor del Milagro, Salta, Argentina, ⁵Reumatologia, Hospital Señor del Milagro, Salta, Argentina
Background/Purpose: Twenty-four hour proteinuria (24hp) has been the gold standard for the screening and follow up of glomerular disease. The use of protein/creatinin urinary index…
Abstract Number: 762 • 2018 ACR/ARHP Annual Meeting
Aquaporin-4 Immunoglobulin G Antibody Positive Neuromyelitis Optica Spectrum Disorder and Systemic Autoimmune Diseases Overlap Syndrome: A Single Center Experience
Eduardo Martín Nares¹, Gabriela Hernandez-Molina¹ and Hilda Fragoso-Loyo², ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, México, Mexico
Background/Purpose: The coexistence of neuromyelitis optica spectrum disorder (NMOSD) with other systemic autoimmune diseases is well recognized, especially with systemic lupus erythematosus (SLE) and Sjögren…
Abstract Number: 763 • 2018 ACR/ARHP Annual Meeting
Comparison of Clinical Characteristics and Outcome between Isolated and Classic Lupus Nephritis
Kubra Bugdayli¹, Cynthia S. Crowson², Ladan Zand³, Mariam P. Alexander⁴, Lynn D. Cornell⁴ and Vaidehi R. Chowdhary⁵, ¹Department of Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, MN, ²Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ⁴Anatomic Pathology, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN
Comparison of clinical characteristics and outcome between isolated and classic lupus nephritisBackground/Purpose: Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE). Rarely,…
Abstract Number: 764 • 2018 ACR/ARHP Annual Meeting
Cardiovascular Disease in SLE at One Center between 1981 and 2016. a Population-Based Study Highlighting the Importance of Disease Duration and Age at Diagnosis
Ola Nived¹, Ragnar F Ingvarsson¹, Anna Jöud², Petrus Linge¹, Helena Tydén¹, Anders A. Bengtsson¹ and Andreas Jönsen¹, ¹Rheumatology, Lund University, Department of Clinical Sciences, Lund, Sweden, ²Division of Occupational and Environmental Medicine, Lund University, Department of Laboratory Medicine, Lund, Sweden
Background/Purpose: Active inflammatory processes characterize early SLE disease, while later morbidity to a considerable extent consists of consequences of organ damage, particularly cardiovascular disease (CVD).…
Abstract Number: 765 • 2018 ACR/ARHP Annual Meeting
Predictors of End-Stage Renal Disease in Lupus Nephritis
Mery Deeb¹, Konstantinos Tselios², Dafna D Gladman², Jiandong Su² and Murray Urowitz³, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toront, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: End-stage renal disease (ESRD) is the most important complication of lupus nephritis (LN) and greatly affects mortality. Its incidence has been estimated at 11%…
Abstract Number: 766 • 2018 ACR/ARHP Annual Meeting
Neutrophil Extracellular Traps Are a Source of Extracellular High Mobility Group Box-1: Association with Clinical and Histopathological Features in Patients with Lupus Nephritis
Laura Patricia Whittall¹, Diana Gómez-Martín¹, Jiram Torres-Ruíz², Alejandro Zentella Dehesa¹, Miguel Tapia-Rodríguez¹ and Jorge Alcocer-Varela¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
Background/Purpose: Current evidence suggests that neutrophils play an important role in the pathophysiology of lupus nephritis (LN) mainly through the secretion of type I IFN…
Abstract Number: 767 • 2018 ACR/ARHP Annual Meeting
Tobacco and Systemic Lupus Erythematosus Relationships: Pay Attention to the Retina!
Iñigo Rúa-Figueroa¹, Celia Erausquin², Antonio Naranjo³, Celia Rua-Figueroa⁴, Soledad Ojeda⁵, Felix Francisco⁵, Juan Carlos Quevedo⁶, Laura Cáceres⁶, Ruben López⁶, Martin Greco⁶, Irene Altabás-González⁶, Francisco Rubiño⁶ and Carlos Rodriguez-Lozano⁷, ¹Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ²Rheumatology Department,, Hospital Doctor Negrin, Las Palmas GC, Spain, ³Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain, ⁴Universidad de Las Palmas de Gran Canaria, Las Palmas GC, Spain, ⁵Hospital Doctor Negrin, Las Palmas GC, Spain, ⁶Rheumatology, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁷Rheumatology, Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain
Background/Purpose: Only a few studies have analyzed the influence of tobacco smoking in SLE in a quantitative way. Furthermore, scanty information exists regarding smoking and…
Abstract Number: 768 • 2018 ACR/ARHP Annual Meeting
Spinal Cord Syndromes Associated with Systemic Lupus Erythematous: Differentiating Lupus Myelitis, Neuromyelitis Optica, and Multiple Sclerosis
Jessica Williams¹, Cameron Speyer¹, David Kreps¹, Karen Costenbader¹ and Shamik Bhattacharyya², ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Neurology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Non-infectious myelitis in SLE is caused by heterogenous disease processes including SLE myelitis, comorbid multiple sclerosis (MS), or anti-aquaporin-4 antibody (AQ4) mediated neuromyelitis optica…
Abstract Number: 769 • 2018 ACR/ARHP Annual Meeting
Herpes Zoster in Systemic Lupus Erythematosus: Prevalence and Risk Factors
Hanan Al Rayes¹, Nicole Anderson², Dennisse Bonilla², Jiandong Su² and Zahi Touma², ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Herpes zoster (HZ) commonly observed in the elderly and in immune-compromised patients. The prevalence of HZ is 3.6-19.9% in previously reported data. The higher…
Abstract Number: 770 • 2018 ACR/ARHP Annual Meeting
Cognitive Function Trajectories Are Associated with the Depressive Symptoms Trajectories in SLE over Time
Zahi Touma¹, Jiandong Su¹ and Patricia Katz², ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of California San Francisco, San Francisco, CA
Background/Purpose: We have shown that cognitive function followed particular trajectories over time in SLE, with some patients having persistently low scores and others normal scores.…

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