ACR Meeting Abstracts

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  • Abstract Number: 1723 • 2019 ACR/ARP Annual Meeting

    Mixed Cryoglobulinaemia Since the Advent of New Direct-acting Antivirals for Hepatitis C Infection: Clinical Characteristics, Etiologies and Biological Features in 679 Patients

    Gonçalo Boleto1, Pascale Ghillani-Dalbin 2, Lucile Musset 2, Patrice Cacoub 1 and David Saadoun 1, 1AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Paris, France, 2Department of Immunology, UF d’Immunochimie et d’autoimmunité, APHP, Groupe Hospitalier Pitié-Salpétrière, Paris, France, Paris, France

    Background/Purpose: Previously chronic hepatitis C virus (HCV) infection was accountable for 80-90% of cases of mixed cryoglobulinemia (MC). The advent of direct-acting antivirals (DAA) has…
  • Abstract Number: 1724 • 2019 ACR/ARP Annual Meeting

    Disease Manifestations and Impact on Quality of Life in Subjects with Pre-Pubertal Onset Systemic Lupus Erythematosus

    Brandi Stevens1, Martha Rodriquez 1, Amy Rakestraw 2 and Kathleen O'Neil 1, 1Indiana University, Indianapolis, IN, 2Indiana University Health, Indianapolis, IN

    Background/Purpose: Systemic Lupus Erythematosus (SLE) can be a severe disease, especially when diagnosed in childhood. Onset prior to puberty (Tanner stage II) is rare, and…
  • Abstract Number: 1725 • 2019 ACR/ARP Annual Meeting

    Disease Activity in Childhood-Onset Systemic Lupus Erythematosus: Initial Analysis of the Childhood Arthritis and Rheumatology Research Alliance Registry

    Emily Smitherman1, Mary Beth Son 2, Andrea Knight 3, Timothy Beukelman 4, Jeffrey Curtis 1 and Aimee Hersh 5, 1University of Alabama at Birmingham, Birmingham, AL, 2Boston Children's Hospital, Boston, MA, 3Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 4University of Alabama Birmingham, Birmingham, AL, 5University of Utah, Salt Lake City, UT

    Background/Purpose: Substantial risk of early morbidity and mortality exists for patients with childhood-onset systemic lupus erythematosus (cSLE) despite widespread use of immunosuppressive therapy. There are…
  • Abstract Number: 1726 • 2019 ACR/ARP Annual Meeting

    Disease Activity and Health Care Utilization Among Young Adults with Childhood-onset Lupus Transitioning to Adult Care: Follow-Up Data from the Pediatric Lupus Outcomes Study

    Sara Haro1, Erica Lawson 2 and Aimee Hersh 3, 1University of California San Francisco, San Francisco, CA, 2University of California San Francisco Benioff Children’s Hospital, San Francisco, CA, 3University of Utah, Salt Lake City, UT

    Background/Purpose: Individuals with childhood-onset systemic lupus erythematosus (cSLE) must transfer from pediatric to adult health care as they enter adulthood. Previous analyses of the Pediatric…
  • Abstract Number: 1727 • 2019 ACR/ARP Annual Meeting

    Worsening Disease Activity and Inability to Taper Corticosteroids in an Ethnically Diverse Cohort of Pediatric-Onset Lupus Patients After Transition to Adult Care

    Marla Guzman1, B.Anne Eberhard 1 and Joyce Hui-Yuen 1, 1Cohen Children's Medical Center, New Hyde Park, NY

    Background/Purpose: Transition of pediatric lupus (pSLE) patients from pediatric to adult rheumatology care is historically difficult and challenging. Although our division routinely assesses for transition…
  • Abstract Number: 1728 • 2019 ACR/ARP Annual Meeting

    Persistent Disease Activity Is Associated with Avascular Necrosis Development in Juvenile Systemic Lupus Erythematosus

    Anthony Hoang 1, Howard Yang 2, Tracy Andrews 3, Jennifer Weiss 4, Kathleen Haines 4, Yukiko Kimura 5 and Suzanne Li4, 1Rutgers University, New Brunswick, NJ, 2David Geffen School of Medicine at UCLA, Santa Monica, CA, 3Rutgers University, Newark, NJ, 4Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, 5Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Cincinnati, OH

    Background/Purpose: Avascular necrosis (AVN) is a serious comorbidity of juvenile systemic lupus erythematosus (jSLE) associated with disability, impaired quality of life, and increased cost of…
  • Abstract Number: 1729 • 2019 ACR/ARP Annual Meeting

    Infections and Mortality in 230 Childhood Lupus Patients: A Single Center Experience from North India

    Sumidha Mittal 1, Manjari Agarwal 1 and Sujata Sawhney1, 1Department of pediatric rheumatology, Sir Ganga Ram Hospital, New Delhi, India, New Delhi, India

    Background/Purpose: Children with systemic lupus erythematosus(cSLE) have more severe disease as compared to adults. Additionally, Asians in their geographic area have high burden of infections…
  • Abstract Number: 1730 • 2019 ACR/ARP Annual Meeting

    Impact of Preceding and Co-existing Autoimmune Cytopenias on Severity of Childhood-onset Systemic Lupus Erythematosus: A Single-Center Retrospective Cohort Study

    Ekemini Ogbu1, Shanmuganathan Chandrakasan 1, Kelly Rouster-Stevens 1, Larry Greenbaum 1, Chelsea Marion 2, Karli Singer 3, Iñaki Sanz 3 and Sampath Prahalad 1, 1Emory University and Children's Healthcare of Atlanta, ATLANTA, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Emory University, Atlanta, GA

    Background/Purpose: Autoimmune cytopenias may precede or occur with childhood-onset systemic lupus erythematosus (cSLE). Adult studies suggest that lupus patients with concurrent autoimmune cytopenias have relatively…
  • Abstract Number: 1731 • 2019 ACR/ARP Annual Meeting

    Validation of the 2017 Weighted Criteria in Pediatric Systemic Lupus Erythematosus (SLE)

    Meiqian Ma 1, Joyce Hui-Yuen2, Jane Cerise 3, Sabah Iqbal 4 and B. Anne Eberhard 5, 1Cohen Children's Medical Center Northwell Health, Lake Success, NY, 2Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY, 3Feinstein Institute for Medical Research, Manhasset, 4Hofstra Northwell School of Medicine, Hempstead, 5Cohen Children's Medical Center Northwell Health, Lake Success

    Background/Purpose: Different classification criteria for systemic lupus erythematosus (SLE) have been proposed over many years. The most widely used and accepted criteria have been the…
  • Abstract Number: 1732 • 2019 ACR/ARP Annual Meeting

    Evaluating the New 2018 ACR/EULAR SLE Classification in Pediatric Patients

    Catherine Strahle1, Angela Merritt 2, Xiaoling Niu 3, Arjun Mathur 4, Allen Watts 2 and Hermine Brunner 5, 1Univeristy of Cincinnati Medical Center, Cincinnati, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Fudan University, Shanghai, Shanghai, China (People's Republic), 4Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

    Background/Purpose: The traditional 1997 ACR SLE classification criteria classify a patient as having SLE if 4 of the 11 criteria have been met over time.…
  • Abstract Number: 1733 • 2019 ACR/ARP Annual Meeting

    Long-term Renal Survival of Pediatric Onset Lupus Patients in a Population-Based Cohort

    Catherine Park 1, Janet Figueroa 1, Cristina Drenkard 1, Laura Plantinga 1, Larry Greenbaum 2 and S Sam Lim1, 1Emory University, Atlanta, GA, 2Emory University and Children's Healthcare of Atlanta, Atlanta, GA

    Background/Purpose: Compared to adult-onset disease, pediatric-onset SLE (p-SLE) has more severe renal involvement. There are no population-based, long-term follow-up studies of pediatric lupus nephritis (LN)…
  • Abstract Number: 1734 • 2019 ACR/ARP Annual Meeting

    Low Bone Mineral Density Was Associated with Lupus Nephritis Irrespective of Duration on Steroid Treatment in a Large Observational Study of Juvenile Systemic Lupus Erythematosus Patients

    Anastasia-vasiliki Madenidou1, Yasmin Mahfouz 2, Oliver Cheng 2, Farah El-Sharnouby 2, Charlene Foley 2 and Coziana Ciurtin 3, 1Centre for Adolescent Rheumatology, University College London London, UK, LOndon, 2Centre for Adolescent Rheumatology, University College London London, UK, London, United Kingdom, 3Centre for Adolescent Rheumatology, University College London London, UK, Londond, United Kingdom

    Background/Purpose: An estimated 10-20% of all patients with systemic lupus erythematosus (SLE) develop clinical disease before the age of 18 years and are therefore classified…
  • Abstract Number: 1735 • 2019 ACR/ARP Annual Meeting

    Clinical Variables Influencing Prednisone Dosing Towards the Development of Corticosteroid Treatment Algorithms in Pediatric Proliferative Lupus Nephritis

    Nathalie Chalhoub1, Tingting Qiu 2, Jianghong Deng 3, Angela Merritt 2, Bin Huang 4 and Hermine Brunner 4, 1The University of Cincinnati College of Medicine, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Beijing Children's Hospital, Beijing, China (People's Republic), 4Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Corticosteroids (CS) are the mainstay of childhood-onset systemic lupus erythematosus (cSLE) and proliferative lupus nephritis (LN) therapy. However, there are no widely accepted CS…
  • Abstract Number: 1736 • 2019 ACR/ARP Annual Meeting

    Cognitive Impairment in Childhood-Onset Systemic Lupus Erythematosus: Early Detection with MRI Spectroscopy and Its Association with MOG Antibodies

    Huseyin Kilic 1, Sezgin Sahin 2, Mekiya Filiz Toprak 3, Gokce Hale Atay 4, Kubra Yilmaz 1, Amra Adrovic 5, Kenan Barut 6, Esin Ozturk Isik 4, Erdem Tuzun 7, Osman Kizilkilic 8, Sema Saltik 1 and Ozgur Kasapcopur9, 1Department of Pediatric Neurology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, 2Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Istanbul, Turkey, 3Department of Pediatric Neurology, Bezmialem Vakif University, School of Medicine, Istanbul, Turkey, Istanbul, Turkey, 4Institute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey, Istanbul, Turkey, 5Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, 6Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, İstanbul, Istanbul, Turkey, 7Department of Neuroscience, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey, Istanbul, Turkey, 8Department of Neuroradiology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, 9Department of Pediatric Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease characterized by the presence of various autoantibodies. Unnoticed and progressive cognitive impairment may develop in…
  • Abstract Number: 1737 • 2019 ACR/ARP Annual Meeting

    Systemic Vascular Involvement in Kawasaki Disease: A Single Center Cohort

    Monica Bray1, Andrea Ramirez 1, Eyal Muscal 1 and Marietta De Guzman 2, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine/Texas Children's Hospital, Houston, TX

    Background/Purpose: Kawasaki disease is classically thought to be a monophasic disease that primarily targets the coronary arteries. The American Heart Association Kawasaki guidelines note that…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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