ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 455 • 2018 ACR/ARHP Annual Meeting

    Metabolic Syndrome and Trajectories of Pain Severity and Number of Painful Sites in Knee Osteoarthritis: Data from a 10.7-Year Prospective Study

    Feng Pan1, Jing Tian2, Flavia Cicuttini3 and Graeme Jones4, 1Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 2Public health unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 3Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, 4Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: Metabolic syndrome (MetS) has been suggested as having a role in osteoarthritis (OA) pathogenesis. No study has assessed whether MetS and its components are…
  • Abstract Number: 456 • 2018 ACR/ARHP Annual Meeting

    Effect of Local and Systemic CCR2 Blockade on Knee Hyperalgesia in a Mouse Model of Osteoarthritis

    Shingo Ishihara1, Rachel E. Miller2, Richard J. Miller3 and Anne-Marie Malfait4, 1Internal Medicine, Rush University Medical Center, Chicago, IL, 2Biochemistry, Rush University Medical Center, Chicago, IL, 3Pharmacology/Medical Humanities and Bioethics, Northwestern University, Chicago, IL, 4Biochemistry & Rheumatology, Rush University Medical Center, Chicago, IL

    Background/Purpose: Surgical destabilization of the medial meniscus (DMM) in the mouse knee results in slowly progressive osteoarthritis (OA), characterized by moderate joint damage by week…
  • Abstract Number: 457 • 2018 ACR/ARHP Annual Meeting

    Neuropathic Pain in Patients with Knee Osteoarthritis (Preliminary Report)

    Pinar Borman1, Ferda Kaygisiz2 and Aysegul Yaman3, 1Department of Physical Medicine and Rehabilitation, University of Hacettepe Faculty of Medicine, Ankara, Turkey, 2Dept of PMR, Ankara Training and Research Hospital, Ankara, Turkey, 3Dept of PMR, University of Hacettepe Faculty of Medicine, Ankara, Turkey

    Background/Purpose: There are limited studies in the literature indicating that neuropathic pain occurs in knee osteoarthritis (OA) (1). The aim of this cross sectional study…
  • Abstract Number: 458 • 2018 ACR/ARHP Annual Meeting

    Validation of the 2012 Systemic Lupus International Collaborating Clinics (SLICC) Classification Criteria Compared to the 1997 Acr Criteria and 2017 Candidate Weighted Criteria for Lupus in Pediatric Patients

    Meiqian Ma1, Jane Cerise2, B. Anne Eberhard3 and Joyce Hui-Yuen4, 1Pediatric Rheumatology, Cohen Children's Medical Center of New York, Lake Success, NY, 2Biostatistics, The Feinstein Institute for Medical Research, Manhasset, NY, 3Pediatric Rheumatology, Cohen Children's Medical center, Lake Success, NY, 4Pediatric Rheumatology, Cohen Children's Medical Center, Lake Success, NY

    Background/Purpose: Different classification criteria for systemic lupus erythematosus (SLE) have been proposed over many years. The most widely used and accepted criteria have been the…
  • Abstract Number: 459 • 2018 ACR/ARHP Annual Meeting

    Readmission Rate within 30 Days of Hospitalization Due to New Onset Lupus Nephritis and Associated Risk Factors: The Importance of Intravenous Pulse Methylprednisolone Therapy

    Angel Alberto Herrera Guerra1, Sampath Prahalad1, Kelly A. Rouster-Stevens1, Rouba Garro2, Leah Bryan3 and Yin Hong4, 1Pediatric Rheumatology, Emory University School of Medicine, Atlanta, GA, 2Pediatric Nephrology, Emory University School of Medicine, Atlanta, GA, 3Pediatrics, Emory University School of Medicine, Atlanta, GA, 4Pathology, Children's Health Care of Atlanta, Atlanta, GA

    Background/Purpose: There is a paucity of data regarding the early hospital readmission rates in newly diagnosed childhood lupus nephritis (cLN). We conducted a retrospective study…
  • Abstract Number: 460 • 2018 ACR/ARHP Annual Meeting

    Immunomodulatory Medication Use for Youth with Newly-Diagnosed Systemic Lupus Erythematosus

    Alaina M. Davis1, Marisa S. Klein-Gitelman2, Jennifer Faerber3, Hannah Katcoff4, Zuleyha Cidav5, David Mandell6 and Andrea M. Knight7, 1Division of Pediatric Rheumatology, Monroe Carell Junior Children's Hospital at Vanderbilt, Nashville, TN, 2Division of Pediatric Rheumatology/PDD PTD, Lurie Children's Hospital of Chicago/Northwestern University, Chicago, IL, 3Division of General Pediatrics, Center for Pediatric Clinical Effectiveness, The Children’s Hospital of Philadelphia, Philadelphia, PA, 4Center for Pediatric Clinical Effectiveness, The Children’s Hospital of Philadelphia, Philadelphia, PA, 5Perelman School of Medicine, Center for Mental Health Policy and Services Research, University of Pennsylvania, Philadelphia, PA, 6Psychiatry and Pediatrics, Center for Mental Health Policy and Services Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 7Division of Rheumatology, Center for Pediatric Clinical Effectiveness & PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: To examine immunomodulatory medication use for youth with systemic lupus erythematosus (SLE) during their first year of care. Methods: We conducted a retrospective cohort…
  • Abstract Number: 461 • 2018 ACR/ARHP Annual Meeting

    Ofatumumab Use in Childhood-Onset Systemic Lupus Erythematosus: A Single-Center Experience

    Anna Carmela Sagcal-Gironella1, Eyal Muscal2, Andrea A. Ramirez1, Monica Marcus3, Miriah Gillispie1, William Blaine Lapin1 and Marietta M. De Guzman4, 1Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Houston, TX, 3Deaprtment of Pediatrics, Division of Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 4Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Ofatumumab is a fully human anti-CD20 monoclonal antibody that has been approved for the treatment of chronic lymphocytic leukemia. It has been increasingly used…
  • Abstract Number: 462 • 2018 ACR/ARHP Annual Meeting

    Steroid Use in Pediatric Proliferative Lupus Nephritis

    Nathalie Chalhoub1, Jianghong Deng2, Natasha M. Ruth3, Stacy P. Ardoin4, Mileka Gilbert5, Theresa Hennard6, Linda Hiraki7, Paul T. Jensen8, Andrea M. Knight9, Rebecca Kunder10, Laura Lewandowski11, Siok Hoon Lily Lim12, Angela Merritt13, Sonia Iqbal Savani14, Mary Beth Son15, Emily von Scheven16, Scott E. Wenderfer17 and Hermine I. Brunner6, 1Division of Immunology, Allergy, and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH, 2Division of Rheumatology, Beijing Children’s Hospital and Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Rheumatology, Medical University of South Carolina, Charleston, SC, 4Division of Rheumatology, Nationwide Children’s Hospital, Columbus, OH, 5Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, 6Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, 8Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, 9Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 10Gilead Sciences, Inc, Redwood City, CA, 11NIAMS/NIH, Bethesda, MD, 12Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada, 13Pediatric Rheumatology, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 14Medical University of South Carolina, Charleston, SC, 15Boston Children's Hospital, Harvard Medical School, Brookline, MA, 16Pediatric Rheumatology, University of California San Francisco, San Francisco, CA, 17Pediatrics-Renal, Baylor College of Medicine, Houston, TX

    Background/Purpose: Corticosteroids (CS) are the mainstay of childhood-onset lupus (cSLE) and proliferative lupus nephritis (LN) therapy. However, there are no widely accepted CS dosing regimens…
  • Abstract Number: 463 • 2018 ACR/ARHP Annual Meeting

    Percentage of Glomerular Crescents Predicts Renal Outcomes in Childhood-Onset Lupus Nephritis

    Pooja Patel1, Marietta M. De Guzman1, Joseph Maliakkal2, Michelle Rheault3, David Selewski4, Katherine Twombley5, Jason Misurac6, Cheryl Tran7, Alexandru Constantinescu8, Ali Mirza Onder9, Meredith Seamon10, Vaishali Singh11, Cynthia Pan11, Joseph Flynn12, Abiodun Omoloja13, William Smoyer14, Guillermo Hidalgo15 and Scott E. Wenderfer16, 1Pediatrics-Rheumatology, Baylor College of Medicine, Houston, TX, 2Pediatrics-Renal, Saint Louis University, St. Louis, MO, 3Pediatrics-Renal, University of Minnesota, Minneapolis, MN, 4Pediatrics-Renal, University of Michigan, Ann Arbor, MI, 5Pediatrics-Renal, Medical University of South Carolina, Charleston, SC, 6Pediatrics-Renal, University of Iowa, Iowa City, IA, 7Pediatrics-Renal, Mayo Clinic, Rochester, MN, 8Pediatrics-Renal, Joe DiMaggio Children’s Hospital, Hollywood, FL, 9Pediatrics-Renal, University of Tennessee, Memphis, TN, 10Pediatrics-Renal, The University of Utah, Salt Lake, UT, 11Pediatrics-Renal, Medical College of Wisconsin, Wauwatosa, WI, 12Pediatrics-Renal, Seattle Children's Hospital, Seattle, WA, 13Pediatrics-Renal, Wright State University, Dayton, OH, 14Pediatrics-Renal, Nationwide Children’s Hospital, Columbus, OH, 15Pediatrics-Renal, East Carolina University, Greenville, NC, 16Pediatrics-Renal, Baylor College of Medicine, Houston, TX

    Background/Purpose: Outcomes for childhood-onset crescentic lupus nephritis are unclear. The revised classification system for lupus nephritis by the Renal Pathology Society clearly distinguishes between cellular,…
  • Abstract Number: 464 • 2018 ACR/ARHP Annual Meeting

    The Long Term Outcomes in Chinese Children Diagnosed with Systemic Lupus Erythematosus and Biopsy Proven Lupus Nephritis – a 18-Year Cohort

    Grace Chiang1,2, Sik Nin Wong3, Clara Law4, Kwok Piu Lee5, Cheuk Chun Szeto6, Chi Chiu Mok7, Lai-Shan Tam8 and Ting Fan Leung9, 1Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, Hong Kong, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Paediatrics and Adolescent Medicine, Tune Mun Hospital, Hong Kong, Hong Kong, 4Medicine and Therapeutics, Alice Ho Miu Ling Nethersole Hospital, Hong Kong, Hong Kong, 5Paediatrics and Adolescent Medicine, Pamela Youde Nethersole Eastern Hospital, Hong Kong, Hong Kong, 6Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 7Medicine and Geriatrics, Tune Mun Hospital, Hong Kong, Hong Kong, Hong Kong, 8Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, Hong Kong, 9Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Background/Purpose: Renal disease occurs in 50-70% of all childhood onset systemic lupus erythematosus (cSLE).  The prevalence of LN is higher in children and the manifestations…
  • Abstract Number: 465 • 2018 ACR/ARHP Annual Meeting

    Seasonal Variation in Cutaneous Flares for Pediatric Lupus

    Tamara Tanner1, Marija Dionizovik-Dimanovski2, Dawn Wahezi3 and Tamar Rubinstein3, 1Albert Einstein College of Medicine/ Children's Hospital at Montefiore, Albert Einstein College of Medicine/ Children's Hospital at Montefiore, Bronx, NY, 2Pediatric Rheumatology, Children's Hospital at Montefiore, Bronx, NY, 3Pediatric Rheumatology, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY

    Background/Purpose: Exposure to sunlight has been proposed as a possible environmental trigger for lupus flares, particularly cutaneous disease. Contradictory findings exist regarding seasonal variation in…
  • Abstract Number: 466 • 2018 ACR/ARHP Annual Meeting

    Improving Pneumococcal Vaccination Rates in Childhood-Onset SLE Patients at a Large Tertiary Care Center: The Path to Creating a More Sustainable Model of Vaccination with the Help of EMR

    Saimun Singla and Marietta M. De Guzman, Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Streptococcus pneumonia is a leading cause of illness in children worldwide and can lead to death in those with an immunosuppressed status. Given the…
  • Abstract Number: 467 • 2018 ACR/ARHP Annual Meeting

    The Prevalence and Clinical Features of Co-Occurring Autoimmunity in Children with Systemic Lupus Erythematosus: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry

    Ohoud AlAhmed1, Vidya Sivaraman2, Melissa Moore-Clingenpeel3, Stacy P. Ardoin4 and Sharon Bout-Tabaku5, 1Pediatric Rheumatology, Nationwide Children's Hospital, Columbus, OH, 2Pediatrics, The Ohio State University, COLUMBUS, OH, 3Research, Nationwide Children's Hospital, Dublin, OH, 4Division of Rheumatology, Nationwide Children’s Hospital, Columbus, OH, 5Rheumatology, Nationwide Children's Hospital, Columbus, OH

    Background/Purpose: The co-occurrence of autoimmune disorders (AI) with systemic lupus erythematosus (SLE) in adults is associated with poor disease outcomes. We describe the co-occurrence of…
  • Abstract Number: 468 • 2018 ACR/ARHP Annual Meeting

    Baseline Features and Outcomes of Pediatric-Onset Discoid Lupus Erythematosus: Interim Data Analysis of a Multicenter Retrospective Cohort Study

    Lisa Arkin1, Kevin A. Buhr2, Cordellia Nguyen3, Heather Brandling-Bennett4, Leslie Castelo-Soccio5, Yvonne Chiu6, Benjamin F. Chong7, Lucia Diaz8, Marisa S. Klein-Gitelman9, Amy Paller10, Jennifer Schoch11, Emily von Scheven12, Victoria P. Werth13, Julie Grossman-Kranseler14, Andrew D. Hudson15, Erin M. Ibler16, Mariana C. Marques17, Reesa L. Monir11, Elana Putterman18 and Kaveh Ardalan19, 1Departments of Dermatology and Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Department of Biostatistics & Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Madison, WI, 4Division of Dermatology; Department of Pediatrics, Seattle Children’s Hospital/University of Washington School of Medicine, Seattle, WA, 5Pediatrics, Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA, 6Pediatrics and Dermatology, Medical College of Wisconsin, Milwaukee, WI, 7Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 8Department of Pediatrics, Division of Dermatology, Dell Children’s Hospital, Austin, TX, 9Department of Pediatrics, Division of Rheumatology, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 10Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, 11Department of Dermatology, University of Florida School of Medicine, Gainesville, FL, 12Department of Pediatrics, Division of Rheumatology, University of California at San Francisco, San Francisco, CA, 13Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 14Departments of Pediatrics, Division of Dermatology, University of Washington School of Medicine, Seattle, WA, 15Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX, 16Departments of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI, 17Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 18Children’s Hospital of Philadelphia, Department of Pediatrics, Section of Dermatology, Children’s Hospital of Philadelphia, Philadelphia, PA, 19Departments of Pediatrics and Medical Social Sciences, Division of Rheumatology, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL

    Background/Purpose: Discoid lupus erythematosus (DLE) is rare in children. Prior studies suggest 25-30% of children with skin-limited DLE are diagnosed with systemic lupus erythematosus (SLE)…
  • Abstract Number: 469 • 2018 ACR/ARHP Annual Meeting

    Clinical Characteristics and Treatment of 25 Children with Systemic Lupus Erythematosus Complicated with Thrombotic Microangiopathy in China

    Ji Li, Pediatrics, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: Thrombotic microangiopathy (TTP) is a rare disease involving multiple organ systems. It is caused by extensive platelet thrombosis in the terminal arterioles and anterior…
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