Abstracts Archive - Page 1029 of 2425 - ACR Meeting Abstracts

Abstract Number: 364 • 2018 ACR/ARHP Annual Meeting
Elevated sCD40L As a Predictive Biomarker of Immune-Related Adverse Events in Patients Receiving Immune Checkpoint Inhibitors
Nicholas Meti¹, Khashayar Esfahani^1,2, Ines Colmegna^1,3, Marvin J. Fritzler⁴, Nathalie A. Johnson^1,5, Ciriaco Piccirillo^1,6, Wilson H. Miller Jr.^1,2 and Marie Hudson^1,7, ¹Department of Medicine, McGill University, Montreal, QC, Canada, ²Department of Oncology, McGill University, Jewish General Hospital, Rossy Cancer Network, Montreal, QC, Canada, ³Division of Rheumatology, McGill University Health Centre, Montreal, QC, Canada, ⁴Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁵Division of Hematology, Jewish General Hospital, Montreal, QC, Canada, ⁶Department of Microbiology & Immunology, McGill University, Montreal, QC, Canada, ⁷Division of Rheumatology, Jewish General Hospital, Montreal, QC, Canada
Background/Purpose: The clinical use of immune checkpoint inhibitors (ICI) has led to outstanding clinical outcomes in previously refractory cancers, but ICI have also been associated…
Abstract Number: 365 • 2018 ACR/ARHP Annual Meeting
Monoclonal Gammopathy in Rheumatic Diseases
Yue Yang, Yuan Jia, Shi Chen, Yin Su and Zhan-Guo Li, Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing, China
Background/Purpose: To analyze the clinical spectrum, laboratory characteristics, and outcomes of monoclonal gammopathy (MG) in patients with rheumatic diseases. Methods: Screening for the presence of…
Abstract Number: 366 • 2018 ACR/ARHP Annual Meeting
Infectious Complications of Immunosuppressive Therapy in Patients with Common Variable Immunodeficiency (CVID) and Inflammatory Arthritis
Fatima Alduraibi¹, Monica Lawrence², Larry Borish² and Adam Carlson³, ¹Department of Medicine, University of Virginia Health System, charlottesville, VA, ²Department of Medicine, Division of Allergy and Immunology, University of Virginia Health System, Charlottesville, VA, ³Department of Medicine, Division of Rheumatology, University of Virginia Health System, Charlottesville, VA
Background/Purpose: Common variable immunodeficiency (CVID) is one of the most common symptomatic primary immunodeficiency syndrome with an incidence of ~1 in 25,000 people. CVID is…
Abstract Number: 367 • 2018 ACR/ARHP Annual Meeting
Incidence of Inflammatory Bowel Disease (IBD) Among Patients (Pts) with Other Chronic Inflammatory Diseases (CID) Treated with Interleukin-17a (IL-17a) or Phosphodiesterase 4 (PDE4) Inhibitors
Bruno Emond¹, Lorie A. Ellis², Soumya D Chakravarty³, Martin Ladouceur¹ and Patrick Lefebvre¹, ¹Analysis Group, Inc., Montréal, QC, Canada, ²Janssen Scientific Affairs, LLC, Horsham, PA, ³Janssen Scientific Affairs, LLC/Drexel University School of Medicine, Horsham/Phila, PA
Background/Purpose: IBD is often associated with other CID, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and psoriasis (PsO). Newer biologic agents…
Abstract Number: 368 • 2018 ACR/ARHP Annual Meeting
Synovianalysis Using Leukocyte Esterase Reagent Strips
Samantha Rodriguez-Muguruza¹, Cristian Morales², Susana Malumbres², Alicia Martinez², Alejandro Olivé-Marqués³, Susana Holgado³, Maria Lourdes Mateo⁴ and Melania Martinez-Morillo⁵, ¹Rheumatology, Hospital Verge de la Cinta, Tarragona, Spain, ²Clinical Biochemistry Service, Germans Trias i Pujol Hospital, Barcelona, Spain, ³Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁴Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, ⁵Rheumatology, Germans Trias i Pujol University Hospital, Barcelona, Spain
Background/Purpose: The analysis of synovial fluid (SF) is an important tool to study joint diseases. SF is classified into non inflammatory, inflammatory and septic according…
Abstract Number: 369 • 2018 ACR/ARHP Annual Meeting
Association of Retroperitoneal Fibrosis with Malignancy and the Pathologic Features of Malignancy with Retroperitoneal Fibrosis
Sang Jin Lee¹, Eon Jeong Nam², Yeong Wook Song³ and Young Mo Kang⁴, ¹Internal medicine, Kyungpook National University Chilgok Hospital, Daegu, Korea, Republic of (South), ²Internal Medicine, Kyungpook National University Chilgok Hospital, Daegu, Korea, Republic of (South), ³Dept of Internal Medicine, Seoul National Univ, Seoul, Korea, Republic of (South), ⁴Dept of Internal Medicine, Kyungpook National Univ Hosp, Daegu, Korea, Republic of (South)
Background/Purpose: Retroperitoneal fibrosis (RPF) is a periaortic sclerotic disease that encases adjacent structures, particularly the ureters. Because it is unclear whether RPF is associated with…
Abstract Number: 370 • 2018 ACR/ARHP Annual Meeting
Rituximab in Idiopathic Retroperitoneal Fibrosis
Veronika Boyeva¹, Hatim Alabsi², Michael Seidman³, Ryan Paterson⁴, Jason Kur⁵, Silvia Chang⁶, Luke Chen⁷ and Mollie Carruthers⁵, ¹Department of Medicine, University of British Columbia, Vancouver, BC, Canada, ²Department of Radiology, King Abdulaziz University, Jeddah, Saudi Arabia, ³Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada, ⁴Department of Urology, University of British Columbia, Vancouver, BC, Canada, ⁵Rheumatology, University of British Columbia, Vancouver, BC, Canada, ⁶Department of Radiology, University of British Columbia, Vancouver, BC, Canada, ⁷Department of Hematology, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Retroperitoneal fibrosis (RPF) is a rare disease characterized by the proliferation of fibrous tissue in the retroperitoneum, most commonly surrounding the aorta from the…
Abstract Number: 371 • 2018 ACR/ARHP Annual Meeting
Therapeutic Efficacy and Safety of Iguratimod in Treating Mild IgG4-Related Diseases
Wen Zhang¹ and Panpan Zhang², ¹Rheuamtology, Peking Union Medical College Hospital, Beijing, China, ²Department of Rheumatology, Peking Union Medical College Hospital, Beijing, China
Background/Purpose: To evaluate the therapeutic efficacy and safety of Iguratimod in the treatment of mild IgG4 related disease (IgG4-RD). Methods: Thirty patients with newly diagnosed…
Abstract Number: 372 • 2018 ACR/ARHP Annual Meeting
Arterial Involvement in Erdheim-Chester Disease: A Retrospective Cohort Study
Michel Villatoro-Villar¹, Michael Bold², Kenneth J. Warrington³, Cynthia S. Crowson⁴, Gaurav Goyal⁵, Mithun Shah⁵, Ronald Go⁵ and Matthew J. Koster¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Radiology, Mayo Clinic, Rochester, MN, ³Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, ⁴Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁵Hematology, Mayo Clinic, Rochester, MN
Background/Purpose: Erdheim-Chester disease (ECD) is a rare histiocytosis of the “L” (Langerhans) group with multisystem involvement that can affect the large and medium sized arteries…
Abstract Number: 373 • 2018 ACR/ARHP Annual Meeting
The Effect of an Intensive Controlled 6-Moth Exercise Program with Subsequent 6-Month Follow-up Period in Patients with Idiopathic Inflammatory Myopathies – Preliminary Data
Maja Spiritovic^1,2, Sabina Oreska^2,3, Hana Storkanova^2,3, Barbora Hermankova^1,2, Petr Cesak⁴, Adela Rathouska², Katerina Kubinova^2,3, Martin Klein^2,3, Lucia Vernerova^2,3, Olga Ruzickova^2,5, Herman F Mann^2,6, Karel Pavelka^2,3, Ladislav Šenolt^2,3, Jiri Vencovsky^2,7 and Michal Tomcik^2,3, ¹Department of Physiotherapy, Faculty of Physical Education and Sports, Charles University, Prague, Czech Republic, Prague, Czech Republic, ²Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, ³Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁴Body Composition Laboratory, Faculty of Physical Education and Sports, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁵Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁶First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, ⁷Department Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Muscle inflammation and weakness, subsequent atrophy and permanent muscle damage in idiopathic inflammatory myopathies (IIM) lead to impaired function, reduced muscle strength, endurance and…
Abstract Number: 374 • 2018 ACR/ARHP Annual Meeting
Nailfold Microangiopathy in Dermatomyositis and Systemic Sclerosis: What Is Different?
Alberto Sulli¹, Carmen Pizzorni¹, Sabrina Paolino², Giorgia Ferrari¹, Veronica Tomatis¹, Barbara Ruaro¹, Vanessa Smith³ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, ³Department of Internal Medicine, Department of Rheumatology, Ghent University Hospital, Department of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium
Background/Purpose: Nailfold videocapillaroscopy (NVC) is a non invasive and useful method to assess peripheral microvascular status and evaluate patients with connective tissue diseases (1). Microvascular…
Abstract Number: 375 • 2018 ACR/ARHP Annual Meeting
Only a Minor Proportion of Individuals with Anti-Aminoacyl-tRNA Synthetase Autoimmunity Presents with the Clinical Picture of “Antisynthetase-Syndrome”
Johannes Knitza, Hannah Schenker, Georg Schett and Jörg Distler, Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Antisynthetase Syndrome is a rare and severe autoimmune inflammatory disease that is associated with autoimmunity against aminoacyl-tRNA synthetase and clinical signs of arthritis, myositis…
Abstract Number: 376 • 2018 ACR/ARHP Annual Meeting
Antisynthetase Syndrome: Prevalence of Serositis in Autoantibody Subsets
Alexis Katz¹, James Bena² and Soumya Chatterjee³, ¹Internal Medicine, Cleveland Clinic, Cleveland, OH, ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ³Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH
Background/Purpose: Antisynthetase Syndrome (AS) is a relatively rare autoimmune disease characterized by interstitial lung disease (ILD), myositis, inflammatory arthritis, Raynaud phenomenon, and mechanic’s hands. Eight autoantibodies (Ab) to…
Abstract Number: 377 • 2018 ACR/ARHP Annual Meeting
Preliminary Validation of Rectus Femoris Muscle Ultrasound in Idiopathic Inflammatory Myopathy Patients
Erica McBride¹, Gulnara Mamyrova¹, Michael Harris-Love², Ahalya Premkumar³, Deloris Koziol⁴, Jianhua Yao³, Lawrence Yao³, Joseph Shrader², Minal Jain², Rodolfo Curiel¹, Frederick W. Miller⁵ and Lisa G. Rider⁵, ¹Department of Medicine, Division of Rheumatology, The George Washington University, Washington, DC, ²Rehabilitation Medicine, National Institutes of Health, Bethesda, MD, ³Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, ⁴Department Biostatistics, National Institutes of Health, Bethesda, MD, ⁵Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD
Background/Purpose: Muscle ultrasound (MUS) offers a cost effective, accessible option for detection of muscle inflammation and atrophy in patients with Idiopathic Inflammatory Myopathies (IIM). The…
Abstract Number: 378 • 2018 ACR/ARHP Annual Meeting
Pulmonary Hypertension in Anti-Synthetase Syndrome
Chantelle Carneiro¹, Pichaya O-Charoen² and Soumya Chatterjee³, ¹Department of Internal Medicine, Cleveland Clinic, Cleveland Heights, OH, ²Department of Medicine - Division of Allergy, Immunology and Rheumatology, Mahidol University, Bangkok, Thailand, ³Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH
Background/Purpose: Clinical manifestations of anti-synthetase syndrome (ASS) include fever, Raynaud phenomenon, mechanic’s hands, inflammatory arthritis, myositis and interstitial lung disease (ILD). Pulmonary hypertension (PH), although…

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