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  • Abstract Number: 1303 • 2019 ACR/ARP Annual Meeting

    Intra-Articular TPX-100 Significantly Delays Pathological Bone Shape Change at 6 and 12 Months in Moderate to Severe Tibiofemoral OA

    Dawn McGuire1, Michael Bowes 2, Alan Brett 2, Neil Segal 3, Meghan Miller 4, David Rosen 4 and Yoshinari Kumagai 4, 1OrthoTrophix, Orinda, CA, 2Imorphics, Manchester, England, United Kingdom, 3University of Kansas Medical Center, Kansas City, KS, 4OrthoTrophix, Oakland, CA

    Background/Purpose: Pathological bone shape changes in the femur precede cartilage changes in knee OA and predict disease onset and progression to joint failure (Neogi 2013;…
  • Abstract Number: 1304 • 2019 ACR/ARP Annual Meeting

    Efficacy and Safety of Hylan G-F 20 versus Intra-Articular Corticosteroids in Patients with Knee Osteoarthritis: A Systematic Literature Review, Meta-Analysis, and Network Meta-analysis

    Xavier Chevalier 1, Brendan Sheehan 2, Craig Whittington 3, Chunyi Ho 4, Wilson Ngai5 and Gustavo Campos 6, 1Department of Rheumatology, Hospital henri Mondor, Paris University XII, Creteil, France, 2Department of Medicine, Dalhousie University, Saint John, NB, Canada, 3Doctor Evidence, Santa Monica, CA, 4Doctor Evidence, Santa Monica, 5Sanofi, U.S. Medical Affairs, Bridgewater, 6Universidade Estadual de Campinas, Campinas, Brazil

    Background/Purpose: Knee OA is a progressive joint disease which affects more than 250 million people worldwide. Meta-analysis (MA) has demonstrated that IA CS were more…
  • Abstract Number: 1305 • 2019 ACR/ARP Annual Meeting

    Quality Improvement in Diagnostic and Therapeutic Arthrocentesis in the Flexed Knee Using Pneumatic Compression of the Suprapatellar Bursa

    Fatemeh Jafari Farshami1, Jaren Trost 2, Wilmer Sibbitt 2, Maheswari Muruganandam 2, Philip Band 3, Monthida Fangtham 1, Nicole Emil 1, William Hayward 4, Luke Haseler 5 and Arthur Bankhurst 1, 1Department of Internal Medicine, Division of Rheumatology and School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM, 2Department of Internal Medicine, Division of Rheumatology and School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, 3Department of Orthopaedic Surgery, Biochemistry & Molecular Pharmacology NYU School of Medicine, New York City, New York City, NY, 4The Department of Exercise and Sport Sciences, New Mexico Highlands University, Las Vegas, NM, 5Faculty of Health Sciences, School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia

    Background/Purpose: Arthrocentesis is an essential procedure in diagnosing inflammatory and septic arthritis and is a basic procedure for intra-articular therapy, including therapeutic arthrocentesis and intra-articular…
  • Abstract Number: 1306 • 2019 ACR/ARP Annual Meeting

    Risk Factors for Pain After Total Joint Replacement in Osteoarthritis: Different Pain Measures, Distinct Predictors?

    Joana Barroso1, Kenta Wakaizumi 2, Thomas Schnitzer 1, Vasco Galhardo 3 and Apkar Apkarian 1, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Chicago, IL, 3Porto University, Porto, Portugal

    Background/Purpose: Prognostic factors for pain persistence after total joint replacement (TJR) in osteoarthritis (OA) have been repeatedly proposed. These factors are commonly considered to act…
  • Abstract Number: 1307 • 2019 ACR/ARP Annual Meeting

    A Prospective, Multi-center, Randomized, Clinical Trial Comparing the Effectiveness and Safety of Cooled Radiofrequency Ablation versus a Single Injection of Hyaluronic Acid in the Management of OA Knee Pain

    Antonia Chen1, Fred Khalouf 2, Michael DePalma 3, Keith Zora 4, Lynn Kohan 5, Maged Guirguis 6, Douglas Beall 7, Eric Loudermilk 8, Matthew Pingree 9, Ignacio Badiola 10 and Jeffrey Lyman 11, 1Brigham and Women’s Hospital, Boston, MA, 2University Orthopedics Center, Altoona, PA, 3Virginia iSpine Physicians, Richmond, VA, 4University Orthopedics Center, State College, PA, 5University of Virginia School of Medicine, Charlottesville, VA, 6Ochsner Clinic Foundation, New Orleans, LA, 7Clinical Investigations, Edmond, OK, 8PCPMG Clinical Research Unit LLC, Anderson, SC, 9Mayo Clinic, Rochester, MN, 10University of Pennsylvania, Philadelphia, PA, 11Institute for Orthopedic Research and Innovation, Coeur d'Alene, IN

    Background/Purpose: This prospective, randomized, multi-center study was conducted to compare pain relief, functional improvement, and the safety of cooled radiofrequency ablation (CRFA) to hyaluronic acid…
  • Abstract Number: 1308 • 2019 ACR/ARP Annual Meeting

    Subject Enrichment Criteria for Phase 3 Studies of Lorecivivint (SM04690), a Potential Disease-Modifying Knee Osteoarthritis Drug: A Post Hoc Study on the Effects of Baseline Comorbid Pain and Joint Space Width on Patient-Reported Outcomes

    Sarah Kennedy 1, Chris Swearingen 1, Jeyanesh Tambiah1, Daniel Clauw 2 and Philip G Conaghan 3, 1Samumed, LLC, San Diego, 2Division of Rheumatology, Department of Internal Medicine and Division of Anesthesia, Michigan Medicine, Ann Arbor, MI, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom

    Background/Purpose: Patient-reported outcomes (PROs) in knee osteoarthritis (OA) trials have been difficult to accurately measure due to heterogenous sources of pain (e.g., from comorbid conditions…
  • Abstract Number: 1309 • 2019 ACR/ARP Annual Meeting

    Concordance of Baseline Pain Measures (Across Two Reporting Instruments) Influences Treatment Effect: Post Hoc Analysis of a Phase 3 Randomized Controlled Trial of Triamcinolone Acetonide Extended-Release in Patients with Knee Osteoarthritis

    Philip G Conaghan1, Edgar Ross 2, Alan Kivitz 3, Dennis Turk 4, Andrew Spitzer 5, Deryk Jones 6, Ryan Lanier 7, Amy Cinar 8, Joelle Lufkin 8 and Scott Kelley 8, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, 2Brigham and Women's Hospital, Boston, MA, 3Altoona Center for Clinical Research, Duncansville, PA, 4University of Washington, Seattle, 5Cedars-Sinai Medical Center, Los Angeles, 6Ochsner Sports Medicine Institute, Harahan, GA, 7Analgesic Solutions, Natick, 8Flexion Therapeutics, Burlington

    Background/Purpose: In a Phase 3 randomized controlled study, differing efficacy results were observed when triamcinolone acetonide extended-release (TA-ER) was compared to conventional TA crystalline suspension…
  • Abstract Number: 1310 • 2019 ACR/ARP Annual Meeting

    Osteoarthritis: What’s in a Name?

    Warren A Katz1, 1Penn Medicine; University of Pennsylvania School of Medicine, Upper Gwynedd, PA

    Background/Purpose: The nomenclature of "osteoarthritis" (OA) has been a source of confusion and likely misdiagnosis for centuries.  Prior to 1759, most patients with joint diseases…
  • Abstract Number: 1311 • 2019 ACR/ARP Annual Meeting

    Prevalence of Symptomatic Axial Osteoarthritis and Poliarticular Phenotypes in Spain: EPISER 2016 Study

    Maite Silva-Díaz1, Francisco J. Blanco 2, Victor Quevedo Vila 3, Daniel Seoane-Mato 4, Sagrario Bustabad-Reyes 5 and on behalf of the Working Group Proyecto EPISER2016 6, 1Servicio de Reumatología. Complexo Hospitalario Universitario A Coruña (CHUAC)-INIBIC, A Coruña, Spain, 2Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, 3Unidad de Reumatología. Hospital Comarcal Monforte de Lemos., Lugo, Spain, 4Unidad de Investigación. Sociedad Española de Reumatología., Madrid, Spain, 5eumatología. Hospital Universitario de Canarias., La Laguna, Santa Cruz de Tenerife, Spain, 6Grupo de trabajo del proyecto EPISER2016, Madrid, Spain

    Background/Purpose: Osteoarthritis (OA) is a heterogeneous group of diseases with common clinical and radiographic manifestations involving the peripheral and axial skeletal. OA is the most…
  • Abstract Number: 1312 • 2019 ACR/ARP Annual Meeting

    Knee Morphology Associates with Tibio-Femoral and Patello-Femoral Osteoarthritis: A Case-Control Study

    Anand Ramachandran Nair1, Weiya Zhang 2, Michael Doherty 2 and Abhishek Abhishek 3, 1Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK, Nottingham, England, United Kingdom, 2Academic Rheumatology, Division of Rheumatology,School of Medicine, University of Nottingham, Nottingham, UKArthritis Research UK Pain Centre, Nottingham, UKNational Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham, UK, Nottingham, England, United Kingdom, 3Academic Rheumatology, School of Medicine, University of Nottingham,Nottingham,UK National Institute for Health Research, Nottingham Biomedical Research Centre, Nottingham,UK, Nottingham, England, United Kingdom

    Background/Purpose: Although several morphological features of the hip joint predispose to hip osteoarthritis (OA), only a few are known to associate with knee OA. The…
  • Abstract Number: 1313 • 2019 ACR/ARP Annual Meeting

    Readmissions After Staged vs Simultaneous Bilateral Total Knee Replacements (TKR)

    Linda Russell1, Bella Mehta 2, Emily Lai 3, Jackie Finik 4, Haley Tornberg 5, Huong Do 1, Anne Bass 6, Peter Sculco 1, Thomas Sculco 5, Lazaros Poultsides 7, Stavros Memtsoudis 5 and Susan Goodman 6, 1Hospital for Special Surgery, New York, 2Hospital for Special Surgery/Weill Cornell Medicine, New York, 3Hospital for Special Surgery Healthcare Research Institute, New York, NY, 4Hospital for Special Surgery, New York, NY, New York, NY, 5Hospital for Special Surgery, New York, NY, 6Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 7NYU Langone Health, New York, NY

    Background/Purpose: The safety of bilateral total knee replacements (BTKR) under the same anesthesia as compared to staging within 12 months is debated.  The advantage is…
  • Abstract Number: 1314 • 2019 ACR/ARP Annual Meeting

    Patient-Specific Reference Values for Objective Physical Function Tests: Cross-Sectional Analysis Using Data from the Osteoarthritis Initiative

    Matthew Harkey1, Lori Lyn Price 2, Kieran Reid 3, Grace Lo 4, Shao-Hsien Liu 5, Kate Lapane 1, Lucas Dantas 6, Timothy McAlindon 7 and Jeffrey Driban 7, 1University of Massachusetts Medical School, Worcester, 2Tufts Medical Center, Tufts University, Boston, MA, 3Tufts University, Boston, 4Center of Excellence Michael E. DeBakey VAMC, Baylor College of Medicine, Houston, TX, 5University of Massachusetts Medical School, Worcester, MA, 6Tufts Medical Center, Boston, 7Tufts Medical Center, Boston, MA

    Background/Purpose: Despite an inter-play between objective physical function measures and various patient characteristics, no large-scale investigations in knee osteoarthritis (KOA) have explored complex interactions or…
  • Abstract Number: 1315 • 2019 ACR/ARP Annual Meeting

    Relation of MRI-detected Structural Damage in the Patellofemoral Joint to Pain and Performance Based Function: The MOST Study

    Jessica Maxwell1, Tuhina Neogi 2, Kay Crossley 3, Erin Macri 4, Daniel White 5, Ali Guermazi 6, Frank Roemer 7, Michael Nevitt 8, Beth Lewis 9, James Torner 10 and Joshua Stefanik 11, 1Northeastern University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3La Trobe University, Victoria, Australia, 4Erasmus MC, Rotterdam, Netherlands, 5University of Delaware, Newark, DE, 6Boston Medical Center, Boston, 7University of Erlangen-Nuremberg, Erlangen, Germany, 8University of California at San Francisco, San Francisco, CA, 9University of Alabama at Birmingham, Birmingham, AL, 10University of Iowa at Iowa City, Iowa City, 11Northeastern University, Boston

    Background/Purpose: Osteoarthritis (OA) of the knee is one of the most common causes of disability in the U.S. Often overlooked, OA specific to the patellofemoral…
  • Abstract Number: 1316 • 2019 ACR/ARP Annual Meeting

    Frail Patients Have Less Pain After Total Hip Replacement

    Lisa Mandl1, Charles Cornell 1, Michael Cross 1, Alejandro Gonzalez Della Valle 1, Mark Figgie 1, Seth Jerabek 1, Marianna Frey 2, John Roberts IV 3, Justin Do 3, Mayu Sasaki 3, Nathaniel Hupert 4, Jackie Finik 3 and Steven Magid 1, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY, 2Hospital for Special Surgery, New York, NY, New York, 3Hospital for Special Surgery, New York, NY, New York, NY, 4Weill Cornell Medicine, New York, NY, New York, NY

    Background/Purpose: To determine whether frailty is associated with patient outcomes 1 year after total hip replacement (THR).Methods: Patients ≥65yo scheduled for elective primary THR for…
  • Abstract Number: 1317 • 2019 ACR/ARP Annual Meeting

    Frail Patients Have Worse Function After Total Knee Replacement

    Lisa Mandl1, Charles Cornell 1, Michael Cross 1, Alejandro Gonzalez Della Valle 1, Mark Figgie 1, Seth Jerabek 1, Marianna Frey 2, John Roberts IV 3, Justin Do 3, Mayu Sasaki 3, Nathaniel Hupert 4, Jackie Finik 3 and Steven Magid 1, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY, 2Hospital for Special Surgery, New York, NY, New York, 3Hospital for Special Surgery, New York, NY, New York, NY, 4Weill Cornell Medicine, New York, NY, New York, NY

    Background/Purpose: To determine whether frailty is associated with patient outcomes 1 year after total knee replacement (TKR).Methods: Patients ≥65yo scheduled for elective primary TKR for…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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