Abstracts Archive - Page 1000 of 2607 - ACR Meeting Abstracts

Abstract Number: 898 • 2019 ACR/ARP Annual Meeting
Ultrasound Demonstrates Rapid Reduction of Crystal Depositions During a Treat-to-target Approach in Gout Patients: Two-year Results from a Longitudinal, Observational Study (NOR-GOUT)
Hilde Hammer¹, Lars Karoliussen ¹, Lene Terslev ², Espen A Haavardsholm ¹, Tore Kvien ³ and Till Uhlig ³, ¹Diakonhjemmet Hospital, Oslo, Norway, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen, Denmark, ³Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway
Background/Purpose: Ultrasound is sensitive for detecting depositions of uric monosodium urate (MSU) crystals and is included in the ACR/EULAR classification criteria for gout. The OMERACT…
Abstract Number: 899 • 2019 ACR/ARP Annual Meeting
Lack of Effect of Tart Cherry Concentrate Dose on Serum Urate in People with Gout
Lisa Stamp¹, Yuqing Zhang ², Christopher Frampton ³, Jill Drake ³, Peter Chapman ⁴, Stephen Duffull ⁵ and Tuhina Neogi ⁶, ¹University of Otago, Christchurch, Christchurch, Canterbury, New Zealand, ²Massachusetts General Hospital, Boston, MA, ³University of Otago, Christchurch, Christchurch, New Zealand, ⁴Christchurch Hospital, Christchurch, New Zealand, ⁵University of Otago, Dunedin, New Zealand, ⁶Boston University School of Medicine, Boston, MA
Background/Purpose: In small studies, cherries and cherry concentrate have been suggested to reduce serum urate and gout flares. The aims of this study were to…
Abstract Number: 900 • 2019 ACR/ARP Annual Meeting
Serum Urate Lowering with Allopurinol Improves Endothelial Function in Young Adults
Angelo Gaffo¹, David Calhoun ², Elizabeth Rahn ¹, Suzanne Oparil ², Peng Li ², Tanja Dudenbostel ², David Redden ², Amy Mudano ², Jeffrey Foster ¹, Daniel Feig ², Stephanie Biggers ² and Kenneth Saag ¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham
Background/Purpose: An effect of serum urate on vascular endothelium has been postulated as a mechanism for its association with hypertension and cardiovascular disease. Prior studies…
Abstract Number: 901 • 2019 ACR/ARP Annual Meeting
Sensitivity of Dual-Energy CT, Ultrasound, and X-Ray for Pseudogout: A Pilot Study
Sara K. Tedeschi¹, Daniel Solomon ², Kathleen Vanni ³, Dong Suh ³ and Stacy Smith ⁴, ¹Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ²Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston
Background/Purpose: Advanced imaging modalities such as ultrasound (US) and dual-energy CT (DECT) can help diagnose crystalline arthritis. DECT is a highly sensitive and specific modality…
Abstract Number: 902 • 2019 ACR/ARP Annual Meeting
The Effects of a Low-Fat, Mediterranean, or Low-Carbohydrate Diet on Serum Urate
Chio Yokose¹, Sharan Rai ², Na Lu ³, Natalie McCormick ⁴, Gary Curhan ⁵ and Hyon K. Choi ¹, ¹Massachusetts General Hospital, Boston, MA, ²Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, ³Massachusetts General Hosptial, Boston, MA, ⁴Massachusetts General Hospital and Harvard Medical School, Boston, MA, ⁵Channing Laboratory and Renal Division, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Gout and hyperuricemia are associated with cardiometabolic comorbidities and increased risk of premature mortality. Often, low-purine (i.e., low-protein) diets are recommended for patients with…
Abstract Number: 903 • 2019 ACR/ARP Annual Meeting
Prevalence of Atopic Features in Classic Autoinflammatory Diseases
Brian Dizon¹, Hirsch komarow ¹, Deborah Stone ¹, Patrycja Hoffmann ¹, Anne Jones ¹, Tina Romeo ¹, Karyl Barron ¹, Ivona Aksentijevich ², Daniel Kastner ¹, Amanda Ombrello ¹, Joshua Milner ¹ and Daniella Schwartz ¹, ¹National Institutes of Health, Bethesda, MD, ²National Institutes of Health, Bethesda
Background/Purpose: Autoinflammatory diseases (AIDs), often caused by single gene mutations, are disorders in which aberrant activation of innate immune cells causes uncontrolled systemic inflammation. Because…
Abstract Number: 904 • 2019 ACR/ARP Annual Meeting
Bone Manifestations in Gaucher Disease: A Monocentric Study of 128 Patients
Yann Nguyen¹, Jérôme Stirnemann ², Monia Bengherbia ¹, Karima Yousfi ¹, Dalil Hamroun ³, Wassim Allaham ⁴, Bruno Fantin ⁴ and Nadia Belmatoug ¹, ¹Centre de reference des maladies lysosomales, Hôpital Beaujon, AP-HP, Clichy, France, ²Hôpitaux Universitaires de Genève, Genève, Switzerland, ³CHRU de Montpellier, Montpellier, France, ⁴Hôpital Beaujon, AP-HP, Clichy, France
Background/Purpose: Gaucher disease (GD) is a rare lysosomal storage disorder caused by mutations in the glucocerebrosidase gene, leading to defective lysosomal acid β-glucosidase. Its incidence…
Abstract Number: 905 • 2019 ACR/ARP Annual Meeting
A Third of Relapsing Polychondritis Patients with Ear Involvement at Presentation Had Airway Involvement at the Last Follow-up with a High Mortality Rate
Jun Shimizu¹, Yoshihisa Yamano ¹, Kimito Kawahata ² and Noboru Suzuki ¹, ¹St. Marianna University School of Medicine, Kawasaki, Japan, ²Rheumatology and Allergology, St. Marianna University School of Medicine, Tokyo, Japan
Background/Purpose: We have reported that 239 patients with relapsing polychondritis (RP) were divided into three subgroups, namely patients with airway involvement (A subgroup, 20% of…
Abstract Number: 906 • 2019 ACR/ARP Annual Meeting
Sarcoidosis as a Systemic Disease. Clinical and Epidemiological Characterization of Systemic Phenotype in 1521 Patients
Soledad Retamozo¹, Roberto Pérez-Alvarez ², Carlos Feijoo-Massó ³, Begoña De Escalante ⁴, Andrés González-García ⁵, Joel Chara-Cervantes ⁶, Ricardo Gómez De La Torre ⁷, Miguel López Dupla ⁸, Ana Alguacil ⁹, Javier Rascón ¹⁰, Mercedes Pérez-Conesa ⁶, Mariona Bonet ¹¹, Angel Robles ¹², José Luis Callejas ¹³, Blanca Pinilla ¹⁴, Eva Fonseca Aizpuru ¹⁵, Patricia Perez Guerrero ¹⁶, Jose Salvador Garcia Morillo ¹⁷, Borja de Miguel ¹⁸, Miriam Akasbi ¹⁹, Silvia Ojea Varona ²⁰, Gloria De La Red Bellvis ²¹, Eva Calvo Begueria ²², Jorge Francisco Gómez Cerezo ²³, Cristina Soler i Ferrer ²⁴, Enrique Peral Gutiérrez De Ceballos ²⁵, Gracia Cruz-Caparrós ²⁶, Sergio Rodríguez Fernández ²⁷, Alberto Gato Diez ²⁸, César Morcillo ²⁹, Inmaculada Ojeda ³⁰, M José Vives ³¹, María Penadés Vidal ³², Moisés De Vicente ³³, Belchin Kostov ³⁴, Lucio Pallarés ¹⁰, Pilar Brito-Zerón ³⁵ and Manuel Ramos-Casals ³⁶, ¹Instituto De Investigaciones En Ciencias De La Salud, Univ. Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Universitario de Ciencias Biomédicas de Córdoba, Córdoba, Argentina., Cordoba, Argentina, ²Department of Internal Medicine, Hospital Alvaro Cunqueiro, Vigo, Spain., Vigo, Spain, ³Hospital Parc Tauli, Sabadell, Sabadell, Spain, ⁴Hospital Clinico, Zaragoza, Spain, Zaragoza, Spain, ⁵Hospital Ramon y Cajal, Madrid, Spain, Madrid, Spain, ⁶Hospital Universitario Miguel Servet, Zaragoza, Spain, Zaragoza, Spain, ⁷Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, Oviedo, Spain, ⁸Systemic Autoimmune Diseases Unit, Hospital Joan XXIII, Tarragona, Spain., Tarragona, Spain, ⁹Hospital Virgen de la Salud, Toledo, Spain, Toledo, Spain, ¹⁰Hospital Son Espases, Palma de Mallorca, Spain, Palma de Mallorca, Spain, ¹¹Department of Internal Medicine, Althaia, Xarxa Assistencial de Manresa, Spain, Manresa, Spain, ¹²Hospital La Paz, Madrid, Spain, Madrid, Spain, ¹³Hospital Clínico San Cecilio, Granada, Spain, Granada, Spain, ¹⁴Systemic Autoimmune Diseases Unit Medicine, Hospital Gregorio Marañón, Madrid, Spain, Madrid, Spain, ¹⁵Department of Internal Medicine, Hospital de Cabueñes, Gijón, Spain, Gijón, Spain, ¹⁶Department of Internal Medicine, Hospital Universitario Puerta del Mar, Cádiz, Spain, Cadiz, Spain, ¹⁷Department of Internal Medicine, Hospital Virgen del Rocio, Sevilla, Spain, Sevilla, Spain, ¹⁸Hospital 12 de Octubre, Madrid, Spain, Madrid, Spain, ¹⁹Hospital Infanta Leonor, Madrid, Madrid, Spain, ²⁰Department of Internal Medicine, Hospital Clínico Universitario de Salamanca-IBSAL. Salamanca, Spain, Salamanca, Spain, ²¹Department of Internal Medicine, Hospital de Santa Coloma de Gramanet, Barcelona, Spain, Barcelona, Spain, ²²Hospital Universitario Puerta del Mar, Cádiz, Spain, Cadiz, Spain, ²³Hospital Infanta Sofía, Madrid, Spain, Madrid, Spain, ²⁴Hospital de Sta Caterina, Girona, Spain, Girona, Spain, ²⁵Department of Internal Medicine, Hospital Virgen Macarena, Sevilla, Spain, Sevilla, Spain, ²⁶Department of Internal Medicine, Hospital de Poniente El Ejido, Almería, Spain, Almeria, Spain, ²⁷Department of Internal Medicine, Hospital da Barbanza, A Coruña, Spain, A Coruña, Spain, ²⁸Department of Internal Medicine, Complejo Hospitalario Albacete, Spain, Albacete, Spain, ²⁹Systemic Autoimmune Diseases Unit, Hospital CIMA-Sanitas, Barcelona, Spain, Barcelona, Spain, ³⁰Department of Internal Medicine, Hospital Valle del Guadiato, Córdoba, Spain, Cordoba, Spain, ³¹Parc Sanitari San Joan de Déu, Sant Boi, Barcelona, Spain, Barcelona, Spain, ³²Department of Internal Medicine, Hospital De Manises, Valencia, Spain, Valencia, Spain, ³³Department of Internal Medicine, Hospital Nuestra Señora del Prado, Talavera, Spain, Talavera, Spain, ³⁴Primary Healthcare Transversal Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Primary Care Centre Les Corts, Consorci d’Atenció Primària de Salut Barcelona Esquerra (CAPSBE). Department of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain., Barcelona, Spain, ³⁵Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic. Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain., Barcelona, Spain, ³⁶Department of Autoimmune Diseases, ICMiD. Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX. Department of Medicine, University of Barcelona, Hospital Clínic, Barcelona, Spain., Barcelona, Spain
Background/Purpose: To characterize the main epidemiological, clinical and radiological features at presentation of sarcoidosis in a large multicenter cohort from Southern Europe.Methods: In January 2016,…
Abstract Number: 907 • 2019 ACR/ARP Annual Meeting
Musculoskeletal Sarcoidosis: Characterization and Clinical Expression of 129 Patients with Granulomatous Infiltration of Bones And/or Muscles
Soledad Retamozo¹, Roberto Pérez-Alvarez ², Esperanza Bueno Juana ³, Carlos Feijoo-Massó ⁴, Andrés González-García ⁵, Joel Chara-Cervantes ⁶, Carmen Yllera Gutiérrez ⁷, Miguel López Dupla ⁸, Ana Alguacil ⁹, Javier Rascón ¹⁰, Mercedes Pérez-Conesa ⁶, Mariona Bonet ¹¹, Angel Robles ¹², José Luis Callejas ¹³, Neera Toledo Samaniego ¹⁴, Eva Fonseca Aizpuru ¹⁵, Patricia Perez Guerrero ¹⁶, Jose Salvador Garcia Morillo ¹⁷, Borja de Miguel ¹⁸, Miriam Akasbi ¹⁹, Rosa Tejera Pérez ²⁰, Gloria De La Red Bellvis ²¹, Eva Calvo Begueria ²², Jorge Francisco Gómez Cerezo ²³, Albert Gómez Lozano ²⁴, Enrique Peral Gutiérrez De Ceballos ²⁵, Gracia Cruz-Caparrós ²⁶, Sergio Rodríguez Fernández ²⁷, Alberto Gato Diez ²⁸, César Morcillo ²⁹, Inmaculada Ojeda ³⁰, M José Vives ³¹, María Penadés Vidal ³², Moisés De Vicente ³³, Belchin Kostov ³⁴, Lucio Pallarés ¹⁰, Pilar Brito-Zerón ³⁵ and Manuel Ramos-Casals ³⁶, ¹Instituto De Investigaciones En Ciencias De La Salud, Univ. Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Universitario de Ciencias Biomédicas de Córdoba, Córdoba, Argentina., Cordoba, Argentina, ²Department of Internal Medicine, Hospital Alvaro Cunqueiro, Vigo, Spain., Vigo, Spain, ³Hospital Clínico, Zaragoza, Spain, Zaragoza, Spain, ⁴Hospital Parc Tauli, Sabadell, Sabadell, Spain, ⁵Hospital Ramon y Cajal, Madrid, Spain, Madrid, Spain, ⁶Hospital Universitario Miguel Servet, Zaragoza, Spain, Zaragoza, Spain, ⁷Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, Oviedo, Spain, ⁸Systemic Autoimmune Diseases Unit, Hospital Joan XXIII, Tarragona, Spain., Tarragona, Spain, ⁹Hospital Virgen de la Salud, Toledo, Spain, Toledo, Spain, ¹⁰Hospital Son Espases, Palma de Mallorca, Spain, Palma de Mallorca, Spain, ¹¹Department of Internal Medicine, Althaia, Xarxa Assistencial de Manresa, Spain, Manresa, Spain, ¹²Hospital La Paz, Madrid, Spain, Madrid, Spain, ¹³Hospital Clínico San Cecilio, Granada, Spain, Granada, Spain, ¹⁴Systemic Autoimmune Diseases Unit Medicine, Hospital Gregorio Marañón, Madrid, Spain, Madrid, Spain, ¹⁵Department of Internal Medicine, Hospital de Cabueñes, Gijón, Spain, Gijón, Spain, ¹⁶Department of Internal Medicine, Hospital Universitario Puerta del Mar, Cádiz, Spain, Cadiz, Spain, ¹⁷Department of Internal Medicine, Hospital Virgen del Rocio, Sevilla, Spain, Sevilla, Spain, ¹⁸Hospital 12 de Octubre, Madrid, Spain, Madrid, Spain, ¹⁹Hospital Infanta Leonor, Madrid, Madrid, Spain, ²⁰Department of Internal Medicine, Hospital Clínico Universitario de Salamanca-IBSAL. Salamanca, Spain, Salamanca, Spain, ²¹Department of Internal Medicine, Hospital de Santa Coloma de Gramanet, Barcelona, Spain, Barcelona, Spain, ²²Hospital Universitario Puerta del Mar, Cádiz, Spain, Cadiz, Spain, ²³Hospital Infanta Sofía, Madrid, Spain, Madrid, Spain, ²⁴Hospital de Sta Caterina, Girona, Spain, Girona, Spain, ²⁵Department of Internal Medicine, Hospital Virgen Macarena, Sevilla, Spain, Sevilla, Spain, ²⁶Department of Internal Medicine, Hospital de Poniente El Ejido, Almería, Spain, Almeria, Spain, ²⁷Department of Internal Medicine, Hospital da Barbanza, A Coruña, Spain, A Coruña, Spain, ²⁸Department of Internal Medicine, Complejo Hospitalario Albacete, Spain, Albacete, Spain, ²⁹Systemic Autoimmune Diseases Unit, Hospital CIMA-Sanitas, Barcelona, Spain, Barcelona, Spain, ³⁰Department of Internal Medicine, Hospital Valle del Guadiato, Córdoba, Spain, Cordoba, Spain, ³¹Parc Sanitari San Joan de Déu, Sant Boi, Barcelona, Spain, Barcelona, Spain, ³²Department of Internal Medicine, Hospital De Manises, Valencia, Spain, Valencia, Spain, ³³Department of Internal Medicine, Hospital Nuestra Señora del Prado, Talavera, Spain, Talavera, Spain, ³⁴Primary Healthcare Transversal Research Group, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Primary Care Centre Les Corts, Consorci d’Atenció Primària de Salut Barcelona Esquerra (CAPSBE). Department of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain., Barcelona, Spain, ³⁵Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic. Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain., Barcelona, Spain, ³⁶Department of Autoimmune Diseases, ICMiD. Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX. Department of Medicine, University of Barcelona, Hospital Clínic, Barcelona, Spain., Barcelona, Spain
Background/Purpose: To analyze the prevalence and characteristics of musculoskeletal sarcoidosis in a large nationwide multicenter cohort.Methods: In January 2016, the Autoimmune Diseases Study Group (GEAS-SEMI)…
Abstract Number: 908 • 2019 ACR/ARP Annual Meeting
Epidemiology and Presentation of Sarcoidosis with and Without HIV Infection
Jennifer Hanberg¹, Liana Fraenkel ² and Amy Justice ³, ¹Yale School of Medicine; West Haven Veteran's Administration, New Haven, CT, ²Yale School of Medicine and VA Connecticut Healthcare System, New Haven, ³Yale School of Medicine; West Haven Veteran's Administration, West Haven, CT
Background/Purpose: Sarcoidosis and HIV are thought of as antithetical, one driven by excess, the other by deficiency, of CD4+ T-cells. However, case reports and series…
Abstract Number: 909 • 2019 ACR/ARP Annual Meeting
Is Long-term High-intensity Strength Training Beneficial or Harmful for Knee Osteoarthritis Patients? The Strength Training and Arthritis Trial (START)
Stephen Messier¹, Shannon Mihalko ², Daniel Beavers ³, Barbara Nicklas ³, Paul DeVita ⁴, J Carr ⁵, David Hunter ⁶, Kimberly Bennell ⁷, Ali Guermazi ⁸, Mary Lyles ³ and Richard Loeser ⁹, ¹Wake Forest University, Winston Salem, ²Wake Forest University, Winston Salem, NC, ³Wake Forest School of Medicine, Winston Salem, NC, ⁴East Carolina University, Greenville, NC, ⁵Vanderbilt University School of Medicine, Nashville, TN, ⁶University of Sydney, Sydney, Australia, ⁷Centre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, Faculty of Medicine Dentistry & Health Sciences, The University of Melbourne, Melbourne, VIC, Australia., Parkville, Victoria, Australia, ⁸Boston University School of Medicine, Boston, MA, ⁹UNC, Chapel Hill, NC
Background/Purpose: Few have studied long-term high-intensity strength training in knee osteoarthritis (OA) patients due to the unsubstantiated belief that it might exacerbate OA symptoms. Our…
Abstract Number: 910 • 2019 ACR/ARP Annual Meeting
Is There Any Role for Opioids in the Management of OA?
Mikala Osani ¹, Stefan Lohmander ² and Raveendhara Bannuru¹, ¹Tufts Medical Center, Boston, MA, ²Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden, Lund, Sweden
Background/Purpose: Opioids have long been prescribed for chronic pain conditions, including osteoarthritis (OA). Although the safety of opioids has been questioned, there is little information…
Abstract Number: 911 • 2019 ACR/ARP Annual Meeting
Perfusion in Bone Marrow Lesions Assessed on Dynamic Contrast-enhanced MRI and Its Association with Pain in Knee Osteoarthritis: A Cross-sectional Study
Cecilie Daugaard¹, Robert Riis ², Elisabeth Bandak ³, Janus Nybing ⁴, Stine Hangaard ³, Henrik Gudbergsen ³, Marius Henriksen ³, Henning Bliddal ³ and Mikael Boesen ⁴, ¹The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Frederiksberg, Sjelland, Denmark, ²Dept. of Radiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ³The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ⁴Dept. of Radiology, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark
Background/Purpose: In osteoarthritis (OA) structural changes are only weakly associated with pain. The reason for this discrepancy remains unknown and the exact cause of knee…
Abstract Number: 912 • 2019 ACR/ARP Annual Meeting
Co-morbidities Associated with Discordance Between Structural Severity and Pain in Osteoarthritis: Implications for Clinical Trial Design in OA – a Post-Hoc Analysis of Data from Two Randomized Controlled Trials
Jonathan Bjerre-Bastos¹, Inger Byrjalsen ², Morten Karsdal ³, Jeppe Andersen ¹ and Asger Bihlet ¹, ¹Nordic Bioscience Clinical Development, Herlev, Denmark, ²Nordic Bioscience, Herlev, Denmark, ³Nordic Bioscience, Copenhagen, Denmark
Background/Purpose: Development of new disease-modifying drugs in osteoarthritis (DMOADs) has proven difficult and is complicated by heterogeneous study populations and insensitive endpoints of structural change,…

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