Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Background/Purpose: There is scarce information on the epidemiology of polymyalgia rheumatic (PMR) and giant cell arteritis (GCA) in Latin America. To estimate incidence and prevalence rates of PMR and GCA in a large university hospital–based health management organization in South America.
Methods: Global, age-specific, and sex-specific incidence and prevalence rates were calculated for members of a Medical Care Program (HIMCP), age ≥ 50 years. Incidence study followed members with continuous affiliation ≥ 6 months from January 2000 to December 2015 until he/she voluntarily left the HIMCP, PMR or GCA were diagnosed, death, or study finalization. Cases from the Rheumatology Section database, electronic medical records, laboratory database, temporal artery biopsy and pharmacy database were filtered with the 2012 EULAR/ACR criteria for PMR or the ACR 1990 criteria for GCA. Prevalence was calculated on January 1, 2015.
Results: : In the study period 176,558 persons contributed a total of 1,046,620 person-years, of who 825 developed PMR for an overall incidence rate (cases per 100,000 person-years) of 78.8 (95% CI 73.4–84.2), 90.1 (95% CI 82.9–97.2) for women, and 58.9 (95% CI 51.1–66.6) for men. Ninety persons developed GCA for an overall incidence rate of 8.6 (95% CI 6.8–10.4), 11.1 (95% CI 8.5–10.6) for women, and 4.2 (2.2–6.3) for men. On January 1, 2015, 899 prevalent PMR cases and 100 prevalent ACG cases were identified from a denominator population of 80335 HIMCP members. Prevalence rates of PMR (percentage of cases in the sample population) were 11.2 per 1000 (95% CI 10.4–11.9) overall, 12.7 (95% CI 11.8–13.7) for women, and 8.2 (95% CI 7.2–9.3) for men, and prevalence rates of GCA were 1.2 per 1000 (95% CI 1–1.4) overall, 1.5 (95% CI 1.2–1.9) for women, and 6.3 (95% CI 3.4–9.3) for men. Patient’s characteristics and incidence and prevalence rates per gender and different age groups are shown in table 1 and figures 1 and 2 respectively.
Conclusion: This study’s incidence and prevalence rates are in the upper range of the rates found around the world. Our peak incidence age for PMR was in the eighth decade for both sexes and for GCA was in the seventh decades for both sexes.
To cite this abstract in AMA style:Martinez P JM, Mollerach FB, Vergara F, Gandino IJ, Scolnik M, Catoggio LJ, Rosa J, Soriano ER. Incidence and Prevalence of Polymyalgia Rheumatic and Giant Cell Arteritis: A 15-Year Study in a Health Care Management Organization [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/incidence-and-prevalence-of-polymyalgia-rheumatic-and-giant-cell-arteritis-a-15-year-study-in-a-health-care-management-organization/. Accessed November 28, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/incidence-and-prevalence-of-polymyalgia-rheumatic-and-giant-cell-arteritis-a-15-year-study-in-a-health-care-management-organization/