Session Information
Date: Sunday, November 8, 2015
Title: Fibromyalgia, Soft Tissue Disorders, Regional and Specific Clinical Pain Syndromes Poster I
Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: Abnormalities in the central
processing of pain may play a role in fibromyalgia and cytokines could be
targets for new therapies. We measured cytokine levels in the blood of patients
with fibromyalgia.
Methods: 35 Fibromyalgia patients followed in a
rheumatology office practice had their blood analyzed for cytokine levels by
the University of Miami Immunology Lab. Normal levels were established in
healthy controls by the lab. The following cytokines were
measured: Pro-inflammatory: TNF alpha, TNF beta, TNF receptor I, TNF
receptor II, interferon gamma , IL 1 alpha, IL 1 beta, IL 6.
Anti-inflammatory: IL 4, IL 5, IL 10, IL 13. IL 17, IL 23.
Results: Abnormally high and low
cytokine levels were:
Conclusion: Higher levels
of certain pro-inflammatory cytokines and lower levels of
anti-inflammatory cytokines were found in these fibromyalgia patients. The
significance of abnormal cytokine levels in fibromyalgia is unclear but
cytokines could be important in the etiology of the disorder.
To cite this abstract in AMA style:
Katz RS, Leavitt H, Pickrell D. Higher Levels of Pro-Inflammatory and Lower Levels of Anti-Inflammatory Cytokines Are Present in Fibromyalgia Patients [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/higher-levels-of-pro-inflammatory-and-lower-levels-of-anti-inflammatory-cytokines-are-present-in-fibromyalgia-patients/. Accessed .« Back to 2015 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/higher-levels-of-pro-inflammatory-and-lower-levels-of-anti-inflammatory-cytokines-are-present-in-fibromyalgia-patients/