Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: Patients with inflammatory myositis have increased prevalence of symptomatic fractures. Early detection of asymptomatic vertebral fractures may help in their prevention. We studied the frequency of asymptomatic vertebral fracture and its risk factors in inflammatory myositis.
Methods: Adults with inflammatory myositis were included and dorsal and lumbar spine lateral radiographs were taken. The scoring was done using Genant’s semi-quantitative method. Besides demographic data, weight, height, postmenopausal status, duration of corticosteroid use, anticonvulsants, calcium supplements, and other co-morbidities like diabetes or hypothyroidism and past history of non-vertebral fracture were recorded. Bone mineral density was done using DEXA. Myositis Damage Index (MDI) was also assessed. All results are expressed in median and IQR.
Results: 100 patients (82 females) with myositis of age 35.5 (28.5-46) years and disease duration 3 (1.81-8.0) years were studied. Twenty patients were postmenopausal women. 35 patients had adult dermatomyositis (DM), 26 each had polymyositis and 26 connective tissue disease associated myositis and 13 had juvenile onset myositis. Forty-six patients had asymptomatic vertebral fractures. 19 patients had more than one fracture. Half the fractures occurred in those with disease
Conclusion: Patients with inflammatory myositis have high prevalance of asymptomatic vertebral fractures.
To cite this abstract in AMA style:Gupta L, Edavalath S, Misra R, Lawrence A. High Prevalence of Asymptomatic Vertebral Fractures in Inflammatory Myositis [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/high-prevalence-of-asymptomatic-vertebral-fractures-in-inflammatory-myositis/. Accessed May 22, 2019.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/high-prevalence-of-asymptomatic-vertebral-fractures-in-inflammatory-myositis/