Session Title: Fibromyalgia, Soft Tissue Disorders and Pain II
Session Type: Abstract Submissions (ACR)
Background/Purpose: We had found in a previous study suggestions of an increased prevalence of depression in the mothers and alcohol abuse in the fathers of fibromyalgia patients. We re-examined this finding in a group of fibromyalgia patients.
Methods: 115 FMS patients and 63 control patients with other rheumatic diseases answered a rheumatology office questionnaire that included questions about whether their mother or father had been diagnosed with or had symptoms of depression, alcoholism, or FMS. The chi-square test of association and Fisher’s exact test were used to compare FMS and control patients with respect to percentages. The Mann-Whitney test was done to compare these groups with respect to age. A 0.05 significance level was used and all tests were two-sided.
Results: 81.7% of the FMS patients and 61.9% of the control patients were women (p = 0.004). The mean age was 48.1 ± 12.3 years for FMS patients and 50.7 13.6 for control patients (p = 0.092). 33.0% of FMS patients and 8.1% of control patients reported a depression diagnosis or symptoms in their mothers (p < 0.001). 26.3% of FMS patients reported a depression diagnosis or symptoms in their fathers, compared to 10.0% of control patients (p = 0.013). Although FMS patients were more likely than control patients to report an alcoholism diagnosis or symptoms in their mothers (9.6% vs. 4.8%. p = 0.38) and fathers (19.2% vs. 10.0%, p = 0.18), the differences were not statistically significant. FMS patients were significantly more likely than control patients to report a FMS diagnosis or symptoms in their mothers (26.4% vs. 3.2%. p < 0.001), but not in their fathers (6.2% vs. 0%, p = 0.083).
Conclusion: FMS patients were significantly more likely than control patients to report that their parents had a diagnosis or symptoms of depression, and significantly more likely to report that their mothers had the diagnosis or symptoms of FMS. No statistically significant differences were found with respect to paternal FMS or maternal or paternal alcoholism.
R. S. Katz,
B. J. Small,
S. M. Ferbert,
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/fibromyalgia-and-parental-medical-histories-of-depression-and-alcoholism/