Session Type: Abstract Submissions (ARHP)
The purpose of this study was to identify factors influencing the Health-related quality of life (HR-QOL) for Korean patients with rheumatoid arthritis and factors associated with each domain of the Health-related quality of life(SF-36).
A total of 299 patients with rheumatoid arthritis were recruited from one University Hospital in Seoul, Korea. Their clinical and socio-demographic data were widely collected by means of interviews, self-administered questionnaires and clinical examinations. Disease activity score in 28 joints (DAS28), patient visual analogue pain scale (100mm), functional disability measured with Korean Health assessment questionnaire (KHAQ), The Functional Assessment of Chronic Illness Therapy-Fatigue, (FACIT-Fatigue), Centers for Epidemiologic Studies Depression (CES-D), sleep scale were assessed. The HR-QOL was assessed by Short Form Health Survey-36 (SF-36). Pearson’s correlation coefficient, stepwise multiple regression analyses were performed to determine the factors influencing HR-QOL and associated with each domain of the SF-36.
Of the 299 subjects with RA, 272 (91%) were women and mean age was 49.5±10.5 years. The mean disease duration was 117 ± 91.2 months. The mean scores of SF-36 physical component summary (PCS) and mental component summary (MCS) were 42.5 ± 7.9, 45.8 ± 10.9.The mean scores of DAS 28, functional disability (KHAQ), visual analog pain scale were 3.83±1.41 , 0.57±0.63 , 34.95±24.43 and FACIT-Fatigue was 36.25±10.43, depression (CES-D) was 15.28±10.07 and sleep quality scale was 44.58±8.46.
On the socio-demographic features, educational level, occupation state, exercise were associated with HR-QOL (SF-36).History of hospitalization within 2 years, ESR(mm/hr), CRP(mg/dl), DAS28 score, visual analog pain, KHAQ, disability index, FACIT-Fatigue, depression (CES-D) and sleep quality scale were associated with all domains of HR-QOL (SF-36). Visual analog pain was strong association with HR-QOL(SF-36) domain of bodily pain (BP) (r=-0.74,p=<.0001) and depression(CES-D) was also strong association with mental component summary (MCS)(r=-0.73,p=<.0001).
In multiple stepwise regression model, KHAQ disability index (p=<.0001) was significant predicting variable of the physical component summary (PCS) and depression (CES-D) (p=<.0001) was significant predicting variable of the mental component summary (MCS) of HR-QOL (SF-36).KHAQ disability index (p=<.0001) was significant predicting variable on the domain of PF(Physical Functioning), RP(Role-Physical), SF(Social Functioning) and the FACIT-Fatigue (p=<.0001) was significant predicting variable on the domain of GH(General Health), RE(Role-Emotional), VT(Vitality) of HR-QOL (SF-36).
The factors influencing HR-QOL were functional disability, fatigue, depression and pain. However various factors are influencing the quality of life for patient with rheumatoid arthritis. It suggests that all healthcare professionals should pay more attention to improve fatigue, depression, pain and prevent progressing disability of patient with rheumatoid arthritis.
K. Y. Sohng,
S. H. Park,
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/factors-influencing-health-related-quality-of-life-hr-qol-for-korean-patients-with-rheumatoid-arthritis/