Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: To evaluate disease characteristics, treatment patterns and comorbidities in patients with polymyalgia rheumatica (PMR) to those with giant cell arteritis (GCA), or with both diseases (PMR+GCA).
Methods: Patients enrolled in the national database of the German Collaborative Arthritis Centres between 2007 and 2014 were stratified to PMR, GCA, PMR+GCA. They were compared with regard to patient characteristics, treatment and comorbidities, subdivided by disease duration. Logistic regression analyses were performed to evaluate the risk of having PMR+GCA and the association of this condition with malignant neoplasms. To put the prevalence of malignant neoplasms into perspective, patients of the three groups were matched with patients with rheumatoid arthritis (RA) by age, sex and disease duration.
Conclusion: Patients with PMR+GCA had higher inflammatory activity, the highest need of glucocorticoids and a high comorbid burden. The observed associations of PMR+GCA with smoking on the one hand and with malignant neoplasms on the other should be further investigated, since both would significantly affect patient education and GCA management.
To cite this abstract in AMA style:Huscher D, Albrecht K, Buttgereit F, Aringer M, Hoese G, Ochs W, Thiele K, Zink A. Disparities in Disease Characteristics, Treatment Pattern and Comorbidities in 1,858 Patients with Polymyalgia Rheumatica, Giant Cell Arteritis or Both Diseases [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/disparities-in-disease-characteristics-treatment-pattern-and-comorbidities-in-1858-patients-with-polymyalgia-rheumatica-giant-cell-arteritis-or-both-diseases/. Accessed January 22, 2022.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/disparities-in-disease-characteristics-treatment-pattern-and-comorbidities-in-1858-patients-with-polymyalgia-rheumatica-giant-cell-arteritis-or-both-diseases/