Correlations between Clinical and Ultrasound Scores of Peripheral Enthesitis and Disease Activity Scores in a Cohort of Spondyloarthritis

Assia Haddouche¹, Sabrina Haid², Siham Bencheikh³, Samy Slimani⁴, Amina Abdessemed⁵, Nadjia Brahimi⁶, Aïcha Ladjouz Rezig⁶ and Fella Hanni⁶, ¹of Medicine, Department of Medicine, University of Algiers 1, Algiers, Algeria, ²medicine, Department of Medicine, University of Algiers 1, Algiers, Algeria, ³EPH HADJOUT, Algiers, Algeria, ⁴Department of Medicine, University of Batna, Batna, Algeria, ⁵Medicine, Department of Medicine, University of Algiers 1, Algiers, Algeria, ⁶Department of Medicine, University of Algiers 1, Algiers, Algeria

Meeting: 2017 ACR/ARHP Annual Meeting

Date of first publication: September 18, 2017

Keywords: Enthesitis, spondylarthropathy and ultrasound

Session Information

Date: Sunday, November 5, 2017

Title: Imaging of Rheumatic Diseases Poster I

Session Type: ACR Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: To look correlations between clinical and ultrasound (US) scores of peripheral enthesitis (PE) and disease activity scores of SpA

Methods: A prospective study of 208 SpAs meeting SpA ASAS criteria. In the same consultation, 30 enthesitic sites per patient were examined clinically and 34 sites per patient were examined with US according to the US OMERACT 2014 definition of enthesitis. PE was assessed by the following clinical scores: Enthesitis Peripheral Score (PES= Sum of symptomatic peripheral entheses sites on clinical examination), Visual Analog Scale of peripheral enthesitis (VAS), Spondyloarthritis Research Consortium of Canada score (SPARCC) as well as the following US enthesitis scores: Acute Enthesitis scorev Correlations between clinical scores and ultrasound scores and disease activity scores were calculated using SPSS software.

Results: A total of 208 patients were included, mainly men (63.5%). The mean age was 40.2 ± 11.7 years. The mean duration of the SpA was 11.8 ± 8.7 years. Axial radiographic SpA was the most frequent phenotype (69.2%). On examination 64.4% of SpA were NSAIDs and 88.9% had active disease (ASDAS-vs and / or ASDAS-crp> 1.3). Tables (1, 2) summarize the results of correlations between clinical scores and US scores and disease activity scores. A weak correlation was found between: the acute enthesitis score and two clinical scores (peripheral enthesitis score, mean score of enthesitic VAS); the global enthesitis score and all clinical enthesitis scores and finally between the SES score and two clinical enthesitic scores (peripheral enthesitis score, mean score of enthesitic VAS).

A moderate correlation was observed between disease activity scores and all US scores of peripheral enthesitis except for the chronic enthesitis score for which the correlation was weak.

Table 1

Scores	PES	VASm Enthestis	SPARCC
Acute Enthesitis	r: 0,15 p: 0,03	r: 0,15 p: 0,03	r: 0,13 p: 0,06
Chronic Enthesitis	r: 0,10 p: 0,15	r: 0,09 p: 0,17	r: 0,09 p: 0,26
Global Enthesitis	r: 0,16 p: 0,02	r: 0,16 p: 0,03	r: 0,14 p: 0,04
Doppler Enthesitis	r: 0,06 p: 0,36	r: 0,07 p: 0,32	r: 0,06 p: 0,42
MASEI	r: 0,13 p: 0,06	r: 0,13 p: 0,23	r: 0,13 p: 0,07
SES	r: 0,13 p : 0,06	r: 0,13 p : 0,04	r: 0,13 p:0,05

Table 2

	ASDAS-vs	ASDAS-crp
PES	r: 0,41* p <0,0001	r: 0,39* p <0,0001
VASm Enthestis	r: 0,43* p <0,0001	r: 0,40* p <0,0001
SPARCC	r: 0,39* p <0,0001	r: 0,38* p<0,0001
Acute Enthesitis	r: 0,33* P <0,0001	r: 0,46* p<0,0001
Chronic Enthesitis	r: 0,18 p: 0,006	r: 0,23 p: 0,002
Global Enthesitis	r: 0,35* p <0,0001	r: 0,46* p<0,0001
Doppler Enthesitis	r: 0,29* p <0,0001	r: 0,34* p<0,0001
MASEI	r: 0,38* p <0,0001	r:0,48* p<0,0001
SES	r: 0,32* p <0,0001	r: 0,42* p<0,0001

Conclusion: All clinical and US scores, except for the chronic enthesitis score, would be of interest in assessing disease activity of SpA. US scores are weakly or even uncorrelated to the peripheral enthesitis clinical scores

Disclosure: A. Haddouche, None; S. Haid, None; S. Bencheikh, None; S. Slimani, None; A. Abdessemed, None; N. Brahimi, None; A. Ladjouz Rezig, None; F. Hanni, None.

To cite this abstract in AMA style:

Haddouche A, Haid S, Bencheikh S, Slimani S, Abdessemed A, Brahimi N, Ladjouz Rezig A, Hanni F. Correlations between Clinical and Ultrasound Scores of Peripheral Enthesitis and Disease Activity Scores in a Cohort of Spondyloarthritis [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 10). https://acrabstracts.org/abstract/correlations-between-clinical-and-ultrasound-scores-of-peripheral-enthesitis-and-disease-activity-scores-in-a-cohort-of-spondyloarthritis/. Accessed .

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