Date: Monday, November 6, 2017
Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Background/Purpose: Osteoporosis is a systemic skeletal disease characterized by a decrease in bone mineral density with alterations in bone microarchitecture and an increased risk of fracture. The World Health Organization asserts that it is a major public health problem and increases morbidity and mortality in elderly patients. The FRAX® score is a tool that estimates the risk of fracture at 10 years. It was adapted to the Ecuadorian population in 2009. The purpose of this study was to identify the risk of fracture of the Ecuadorian population using the FRAX® Ecuador calculator and compare the results with FRAX® Colombia, Brazil and the United States (Hispanics).
Methods: A retrospective study that included the Ecuadorian population between 40-90 years old, who underwent bone densitometry between 2013-2015, and whose risk of fracture was assessed with FRAX® Ecuador, Colombia, Brazil and the United States (Hispanics). The DXA values considered were: Osteopenia: T Score -1.0 -2.5 and Osteoporosis: T Score ≥2.5.
Results: We analyzed 1154 patients with a mean age of 61.39 [SD 11.07] (26-97). The predominant gender was female with 88.6% (1022) versus 11.4% (132) male. The mean age of menopause was 45.81 [SD 5.5]. The diagnoses according to bone densitometry were: 18.8% (217) normal, 32.3% (373) osteopenia and 48.9% (564) osteoporosis. The risk of major osteoporotic fracture of the population using FRAX® Ecuador was 1.5% (0.3-27%) and hip 0.5% (0-22%). For FRAX Colombia: 3.0% (0.2-40%) for major osteoporotic fracture and 0.8% (0-34%) for hip fracture. With FRAX® Brazil, 4.2% (1.2-56) was obtained for major osteoporotic fracture and 1.3% (0-49%) for a hip. Finally, FRAX® USA (Hispanic) had a risk of 5.1% (0.7-59%) for major osteoporotic fracture and 1.2% (0-50%) for hip fracture.
Conclusion: The risk of fracture for the Ecuadorian population according to the FRAX® Ecuador calculator was 1.5% for major osteoporotic fracture and 0.5% for hip fracture. Surprisingly, this population presents a low risk of fracture using the calculator of this country, in comparison to the scores obtained using the FRAX® of Colombia, Brazil and the United States (Hispanic). This may indicate that the risk of fracture may be underestimated with FRAX® Ecuador, although more specific studies are needed.
To cite this abstract in AMA style:Maldonado G, Paredes C, Guerrero R, Mieles M, Intriago MJ, Messina O, Ríos C. Comparative Study of Frax® Score in Ecuadorian Population [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 10). https://acrabstracts.org/abstract/comparative-study-of-frax-score-in-ecuadorian-population/. Accessed November 12, 2019.
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