ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 2940

Bechet’s Disease and Sleep Quality in Korean Patients

Chang-Nam Son1, Ji Min Lee1, Hye-Jin Jeong2, Ji-Min Kim1, Sang-Hyon Kim1, Sung Soo Kim3 and Seung-Hyeon Bae4, 1Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea, The Republic of, 2Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Ulsan University School of Medicine, GangNeung Asan Hospital, Gangneung, South Korea, 4Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

Meeting: 2016 ACR/ARHP Annual Meeting

Date of first publication: September 28, 2016

Keywords: , ,

Session Information

Date: Tuesday, November 15, 2016

Title: Vasculitis - Poster III: Rarer Vasculitides

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose:  Behcet’s disease is a chronic, systemic vasculitis that can involve all sizes of blood vessels. Sleep disturbance is one of the most particular concerns in patients with Behcet’s disease. It has been known that the disease activity of rheumatoid arthritis and ankylosing spondylosis is associated with the sleep quality. However, studies about the sleep quality of patients with Behcet’s disease in Korean population are limited. The purpose of this study was to find out the effects of sleep quality on Behcet’s disease in Korean population. We also investigated the relationship between depression, quality of life, other clinical findings and Behcet’s.

Methods:  The study was performed by cross-sectional design in two tertiary hospitals. We surveyed one hundred patients with Behcet’s disease. Sleep quality was assessed by the Korean version of Pittsburgh sleep quality index (PSQI). Disease activity of Behcet’s disease was evaluated by Behcet’s disease current activity form (BDCAF). Depression was assessed by the Korean version of Beck depression inventory second edition (BDI-2). Quality of life was assessed by the Korean version of the Leeds Behcet’s Disease Quality of Life Measure (BDQoL).

Results:  Among 100 patients, median age was 51 [44.5-56.0] years, median disease duration was 77.5 [24.0-136.0] months and 69% were female. Those who met the diagnostic critera of fibromyalgia were 28 patients. The frequency of poor sleep quality (PSQI ≥9) was 42%. Patients with poor sleep quality tend to have higher BDI2, BDCAF and pain VAS score (P = 0.022, P = 0.005 and P < 0.001). Female rate was significantly higher, and BDQoL was lower in poor sleeper group (P = 0.004 and P < 0.001). Among 7 PSQI components, daytime dysfunction was higher in patients with high disease activity (P = 0.03). Total PSQI score were strongly correlated with BDCAF score, BDI-2 score, BDQoL score, and pain VAS score (P = 0.02 , P < 0.001, P < 0.001, and P < 0.001, respectively).

Conclusion:  The low quality of sleep is associated with disease activity, depression and quality of life in Korean patients with Behcet’s disease. Better disease control will improve the sleep quality.

Disclosure: C. N. Son, None; J. M. Lee, None; H. J. Jeong, None; J. M. Kim, None; S. H. Kim, None; S. S. Kim, None; S. H. Bae, None.

To cite this abstract in AMA style:

Son CN, Lee JM, Jeong HJ, Kim JM, Kim SH, Kim SS, Bae SH. Bechet’s Disease and Sleep Quality in Korean Patients [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/bechets-disease-and-sleep-quality-in-korean-patients/. Accessed .

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