Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: To analyse the prevalence of autoimmune diseases (ADs) in Catalonia by using a public big data program (Public Data Analysis for Health Research and Innovation Program, PADRIS)
Methods: We used the health insurance database of the Catalan National Health Insurance (CNHI) which includes all catalan insured population in 2016 (7,483,761 inhabitants). ADs were identified according to the corresponding International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. A total of 33 autoimmune diseases were analysed classified in 4 main categories: rheumatic, systemic, organ-specific and immunodeficiency/autoinflammatory. The prevalence of ADs was calculated as the number of ADs patients divided by the total CNHI beneficiaries in the same year (rate per 100,000 persons, 95% confidence intervals -CI-).
Results: In Catalonia, the overall prevalence of ADs was 1,202 per 100,000 persons (95%CI 1,194-1,209); the prevalence was 1,455 (95%CI 1,443-1,467) in women and 939 (95%CI 929-949) in men. ADs were identified as organ-specific (43%), systemic (33%), rheumatic (23%) and immunodeficiency/autoinflammatory (1%) autoimmune diseases. The Top Ten of ADs with the highest prevalence rates included cutaneous psoriasis (282 cases per 100,000), rheumatoid arthritis (178 cases per 100,000), polymyalgia rheumatic (98 cases per 100,000), spondyloarthropathies (92 cases per 100,000), vasculitis (91 cases per 100,000), systemic lupus erythematosus (68 cases per 100,000), Sjšgren’s syndrome (59 cases per 100,000), celiac disease (58 cases per 100,000), multiple sclerosis (57 cases per 100,000) and psoriatic arthritis (43 cases per 100,000). In 26 (79%) of the 33 ADs, the female:male ratio was higher than 1; the highest ratios were reported for Sjšgren’s syndrome (10.5), primary biliary cholangitis (5.8), SLE (5.4), systemic sclerosis (3.4) and rheumatoid arthritis (2.6). We found a significant geographical variation in the prevalence of the main diseases (Figure 1).
Conclusion: Nearly 90,000 catalans are classified as having an autoimmune disease, representing a prevalence of 1.2% of the total population in Catalonia, a rate that reaches 1.5% in women. We found a different territorial distribution of the main diseases, suggesting a significant influence of geographically-driven determinants in the prevalence of autoimmune diseases.
To cite this abstract in AMA style:Sisó-Almirall A, Kostov B, Martínez Carbonell E, Retamozo S, Flores-Chavez A, González-Martínez S, Brito-Zerón P, Dedéu Baraldés A, Benavent Àreu J, Ramos-Casals M. Autoimmune Diseases in Catalonia: A Population Based Study Using a Public Big Data Program [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/autoimmune-diseases-in-catalonia-a-population-based-study-using-a-public-big-data-program/. Accessed October 30, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/autoimmune-diseases-in-catalonia-a-population-based-study-using-a-public-big-data-program/