Association of Smoking and Cognitive Function in Patients with Fibromyalgia

Lin Ge^1,2, Terry H. Oh³, Ann Vincent⁴, Arya Mohabbat⁵, li Jiang⁶, Mary Whipple⁷, Samantha McAllister⁸, Zhen Wang⁹ and WenChun Qu¹⁰, ¹Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, ²Rheumatology, Guang An Men Hospital, China Academy of Chinese Medical Science,, Beijing, China, ³Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, ⁴General Internal Medicine, Mayo Clinic, Rochester, MN, ⁵Department of Medicine, Mayo Clinic, Rochester, MN, ⁶Rehabilitation, The Third Affiliated Hospital，Sun Yat-sen University,China, Guangzhou, China, ⁷Fibromyalgia and Chronic Fatigue Clinic, Mayo Clinic, Rochester, MN, ⁸Mayo Clinic, Rochester, MN, ⁹Health Sciences Research, Mayo Clinic, Rochester, MN, ¹⁰Department Physical Medicine and Rehabilitation, Department of Anesthesiology Division of Pain Medicine, Mayo Clinic, Rochester, MN

Meeting: 2015 ACR/ARHP Annual Meeting

Date of first publication: September 29, 2015

Keywords: Cognitive dysfunction, fibromyalgia and tobacco use

Session Information

Date: Sunday, November 8, 2015

Title: Fibromyalgia, Soft Tissue Disorders, Regional and Specific Clinical Pain Syndromes Poster I

Session Type: ACR Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose:

To evaluate the association between smoking and cognitive function in patients with fibromyalgia (FM).

Methods:

We surveyed 668 patients with FM from May 2012 through November 2013. Patients were categorized by smoking status (non-smoker and smoker). Primary outcomes included cognitive symptoms (MASQ). Secondary outcomes include fatigue (MFI-20), sleep (MOS-sleep Scale), depression (PHQ-9), anxiety (GAD-7), overall FM symptom severity (FIQ-R), and quality of life (SF-36). Univariate and multivariate analyses were used.

Results:

Ninety-four (14.07%) patients self-identified as smokers. Smokers were associated with several demographic variables, including lower education, unmarried status, and younger age. Smokers reported worse cognitive functions, including total functional score and 4 out of 5 domains of the MASQ (all p<0.05) Secondary outcomes showed worse sleep (MOS-sleep scale p=0.01), anxiety (GAD-7 total p=0.001), depression (PHQ-9 p=0.04), FM symptom severity (FIQ-R total score p<0.01), and QoL in bodily pain(BP) and mental health(MCS) (SF-36: BP p=0.03; MCS p=0.02).

Conclusion:

The results of this study indicate that smokers with FM report worse cognitive function. Although the cause-effect relationship between smoking and cognition is unclear, clinicians who care for patients with FM should be aware of this association.

Disclosure: L. Ge, None; T. H. Oh, None; A. Vincent, None; A. Mohabbat, None; L. Jiang, None; M. Whipple, None; S. McAllister, None; Z. Wang, None; W. Qu, None.

To cite this abstract in AMA style:

Ge L, Oh TH, Vincent A, Mohabbat A, Jiang L, Whipple M, McAllister S, Wang Z, Qu W. Association of Smoking and Cognitive Function in Patients with Fibromyalgia [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/association-of-smoking-and-cognitive-function-in-patients-with-fibromyalgia/. Accessed .

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