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Abstract Number: 1791

Applicability of the 2006 European League Against Rheumatism (EULAR) Criteria for the Classification of Henoch-Schönlein Purpura. an Analysis Based on 766 Patients with Cutaneous Vasculitis

Montserrat Santos-Gómez1, Francisco Ortiz Sanjuan1, Jose L. Hernández2, Marcos A. González-López3, Ricardo Blanco1, Javier Loricera1, Vanesa Calvo-Río1, Trinitario Pina Murcia4, Carmen Gonzalez-Vela5, Marina Lacalle3, Javier Rueda-Gotor1, Lino Álvarez6, Leyre Riancho-Zarrabeitia1 and Miguel A. González-Gay1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 2Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Dermatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 4Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, 5Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 6Pediatrics, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: Henoch-Schönlein purpura and vasculitis

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Session Information

Session Title: Vasculitis

Session Type: Abstract Submissions (ACR)

Background/Purpose

The European League Against Rheumatism (EULAR) proposed in 2006 a new classification criteria for Henoch-Schönlein Purpura (HSP). We aimed to establish the applicability of these criteria in patients with primary cutaneous vasculitis (CV). We also compared these criteria with previously established classification criteria for HSP.

Methods

A series of 766 (346 women/420 men; mean age 34 years) consecutive unselected patients with CV was assessed. Of them, 124 with secondary CV or with CV associated to other well defined entities were excluded from the analysis. The 2006 EULAR criteria for HSP were tested in the remaining 642 patients with primary CV. Two sets of criteria for HSP were also used for comparisons: a) the 1990 American College of Rheumatology (Arthritis Rheum 1990; 33: 1114-21), and b)the ACR-modified criteria proposed by Michel et al. in 1992  (J Rheumatol 1992; 19: 721-8).

Results

451 (70.2%) of 642 patients were classified as having HSP according to the EULAR-2006 criteria, 405 (63.1%) using the ACR-1990 criteria, and 392 (61.1%) by the Michel-1992 criteria. However, only 336 patients (52.3%) met at the same time the EULAR-2006 and the ACR-1990 criteria, and only 229 patients (35.7%) fulfilled both the EULAR-2006 and Michel et al criteria. Noteworthy, only 276 (43%) patients met the three set of criteria. Children fulfilled all the sets of criteria more commonly than adults (215 [66.6%] of 323 versus 61 [19%] of 319 respectively; p<0.0001).  

Conclusion

According to our results, the EULAR-2006 criteria show a poor concordance with previous sets of classification criteria for HSP.


Disclosure:

M. Santos-Gómez,
None;

F. Ortiz Sanjuan,
None;

J. L. Hernández,
None;

M. A. González-López,
None;

R. Blanco,
None;

J. Loricera,
None;

V. Calvo-Río,
None;

T. Pina Murcia,
None;

C. Gonzalez-Vela,
None;

M. Lacalle,
None;

J. Rueda-Gotor,
None;

L. Álvarez,
None;

L. Riancho-Zarrabeitia,
None;

M. A. González-Gay,
None.

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