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  • Abstract Number: 0133 • ACR Convergence 2024

    The Association Between Gout and Gallstone Disease: US General Population Analysis

    Chio Yokose1, Bohang Jiang2, Natalie McCormick2, Sharan Rai2 and Hyon K. Choi3, 1Massachusetts General Hospital, Waltham, MA, 2Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital, Lexington, MA

    Background/Purpose: Gout is associated with kidney stones, but its association with gallstone disease is not known. Gout and gallstone disease have several shared risk factors…
  • Abstract Number: 0142 • ACR Convergence 2024

    The Impact of Hospital Region on Mortality and Other Outcomes in Patients with Gout: A Two-Year Nationwide Analysis

    Nidaa Rasheed1, kHALED ABDULLAH2 and Candice Reyes3, 1UCSF Fresno, Fresno, CA, 2UCSF FRESNO, FRESNO, 3VACCHCS, Fresno, CA

    Background/Purpose: Gout is characterized by chronic inflammatory arthritis caused by the deposition of monosodium urate crystals and leads to increased risk of complications, such as…
  • Abstract Number: 0153 • ACR Convergence 2024

    Frequencies and Rates of All-Cause Emergency Visits and Hospitalizations in Persons with Inflammatory Arthritis Conditions and Gout: A Systematic Review

    Kara Irwin, Ran Huo, Claire Barber and Cheryl Barnabe, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Despite advances in the management of inflammatory arthritis (IA) and gout, many patients still access acute care services. This may be related to their…
  • Abstract Number: 0178 • ACR Convergence 2024

    Are Participants in Gout Clinical Trials Representative of People with Gout in the General Population?

    Jendy Liu, Gregory Gamble and Nicola Dalbeth, University of Auckland, Auckland, New Zealand

    Background/Purpose: Ensuring study participants are representative of the general population is important to ensure that efficacy and safety findings of clinical trials are generalizable in…
  • Abstract Number: 0206 • ACR Convergence 2024

    Urate Lowering Therapy to Acute Treatment Ratio (ULTrA) Index – a Novel Quality Indicator Associated with Reduced Hospital Admissions for Gout

    May Shuen Tang, Frank Sen Hee Tay, Amelia Santosa, Shikha Kumari, Pamela Lim, Htet Htet Aung, Su Zin Thinn, Peter Cheung and Manjari Lahiri, National University Hospital, Singapore, Singapore

    Background/Purpose: Gout is sub-optimally managed with under-prescribed urate lowering therapy (ULT) leading to frequent flares, increased healthcare utilization and cost.To study the burden of gout…
  • Abstract Number: 0265 • ACR Convergence 2024

    Performance of Two Gout Remission Definitions in a Two-Year Randomized Controlled Trial of Nurse-led Care

    Dansoa Tabi-Amponsah1, Michael Doherty2, Aliya Sarmanova3, Weiya Zhang2, Sarah Stewart4, William Taylor5, Lisa Stamp6 and Nicola Dalbeth7, 1The University of Auckland, Auckland, New Zealand, 2Academic Rheumatology, School of Medicine, University of Nottingham; Pain Centre Versus Arthritis, University of Nottingham, Nottingham, United Kingdom, 3Roche Diagnostics International, Clinical Development and Medical Affairs, Nottingham, England, United Kingdom, 4Auckland University of Technology, Auckland, New Zealand, 5The University of Otago, Wellington, Wellington, New Zealand, 6University of Otago, Christchurch, Christchurch, New Zealand, 7University of Auckland, Auckland, New Zealand

    Background/Purpose: To compare the performance of the 2016 preliminary gout remission definition and a simplified gout remission definition in a clinical trial of nurse-led gout…
  • Abstract Number: 0266 • ACR Convergence 2024

    Analysis of Gout Remission Definitions in a Randomised Controlled Trial of Colchicine Prophylaxis for People with Gout Initiating Allopurinol

    Dansoa Tabi-Amponsah1, Lisa Stamp2, Anne Horne3, Jill Drake4, Sarah Stewart5, Gregory Gamble3, Keith Petrie1 and Nicola Dalbeth3, 1The University of Auckland, Auckland, New Zealand, 2University of Otago, Christchurch, Christchurch, New Zealand, 3University of Auckland, Auckland, New Zealand, 4University of Otago, Christchurch, New Zealand, 5Auckland University of Technology, Auckland, New Zealand

    Background/Purpose: To investigate the effect of colchicine prophylaxis on gout remission when commencing urate lowering therapy (ULT), and illness perceptions of people in remission, using…
  • Abstract Number: 0267 • ACR Convergence 2024

    IL-17 Participates in the Pathogenesis of Chronic Gouty Arthritis

    Hong Di1, Xinxin Han1, Yun Zhang2 and Xuejun Zeng1, 1Peking Union Medical College Hospital, Beijing, China, 2Peking Union Medical College Hospital (CAMS), Beijing, China

    Background/Purpose: Chronic gouty arthritis (CGA) is different from acute gouty arthritis  (AGA), its main characteristics include repeated or even persistent joint symptoms, tophus and bone destruction.…
  • Abstract Number: 0268 • ACR Convergence 2024

    Weight Loss Induced by Anti-obesity Medications and Gout Among Overweight and Obesity Individuals: A Population-based Cohort Study

    Jie Wei1, Yilun Wang2, Nicola Dalbeth3, Junqing Xie4, Jing Wu5, Chao Zeng6, Guanghua Lei7 and Yuqing Zhang8, 1Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic), 2Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 3University of Auckland, Auckland, New Zealand, 4Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 5Hunan Key Laboratory of Joint Degeneration and Injury, Changsha, China (People's Republic), 6Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China (People's Republic), 7Department of Orthopaedics, Xiangya Hospital, Central South University; Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China (People's Republic), 8Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School; The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Weight loss is conditionally recommended for gout management; however, the magnitude of the effect of weight loss on incident gout and recurrent gout flares…
  • Abstract Number: 0271 • ACR Convergence 2024

    Intercritical Gout Represents a Systemic Inflammatory State

    Tanner Ourada1, Austin Wheeler2, Michael Duryee2, Bryant England2, Richard Reynolds3, James O'Dell2, Jeff Newcomb2, Michael Pillinger4, Robert Terkeltaub5, Ryan Ferguson6, Mary Brophy6, Tony Merriman7 and Ted Mikuls2, 1University of Nebraska-Medical Center: College of Medicine, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University of Alabama at Birmingham, Birmingham, AL, 4New York University Grossman School of Medicine, New York,, NY, 5Retired, San Diego, CA, 6Veterans Affairs, Boston, MA, 7University of Alabama at Birmingham, Homewood, AL

    Background/Purpose: The presence of systemic inflammation during gout flares is well characterized. While initial research suggests inflammation persists in intercritical gout, these reports have come…
  • Abstract Number: 0273 • ACR Convergence 2024

    Barriers and Facilitators for Outpatient Follow-Up After an Acute Gout Flare: A Qualitative Research Study

    Elizabeth Lopez1, Lesley Jackson2, Kenneth Saag3 and Maria I. ("Maio") Danila4, 1University of Alabama at Birmingham, Montgomery, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3The University of Alabama at Birmingham, Birmingham, AL, 4University of Alabama at Birmingham (UAB), Birmingham VA Medical Center, Birmingham, AL

    Background/Purpose: Many people with gout utilize the emergency department (ED) for acute gout care, but many do not receive subsequent adequate outpatient care for long-term…
  • Abstract Number: 0274 • ACR Convergence 2024

    Cost-effectiveness of Low Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start-Low Go-Slow” Approach for Gout

    Yana Pryymachenko1, Ross Wilson1, Haxby Abbott1, Nicola Dalbeth2 and Lisa Stamp3, 1University of Otago, Dunedin, New Zealand, 2University of Auckland, Auckland, New Zealand, 3University of Otago, Christchurch, Christchurch, New Zealand

    Background/Purpose: To investigate the cost-effectiveness of low-dose colchicine prophylaxis for reducing gout flares when starting allopurinol using the “start-low go-slow” approach.Methods: This was a pre-planned…
  • Abstract Number: 0278 • ACR Convergence 2024

    Efficacy and Safety of Genakumab versus Compound Betamethasone in Gout: The GUARD-1 Study

    Yu Xue1, Tianshu Chu2, Jiankang Hu3, Wei Gou4, Ning Zhang5, Juan Li6, Jing Yu7, Songping Li8, Songbin Li9, Long Qian10, Xinwang Duan11, Lihua Duan12 and Hejian Zou1, 1Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China, Shanghai, China (People's Republic), 2Department of Rheumatology, Henan Provincial People's Hospital, Zhengzhou, China, Zhengzhou, China (People's Republic), 3Department of Rheumatology, Pingxiang People's Hospital, Pingxiang, China, Pingxiang, China (People's Republic), 4Department of Rheumatology, Hebei Petro China Central Hospital, Langfang, China, Langfang, China (People's Republic), 5Department of Rheumatology, Shengjing Hospital of China Medical University, Shenyang, China, Shenyang, China (People's Republic), 6Department of Rheumatology, The First Affiliated Hospital of Hainan Medical University, Haikou, China, Haikou, China (People's Republic), 7Department of Rheumatology, The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China, Shenyang, China (People's Republic), 8Department of Rheumatology, The First Affiliated Hospital of Ganna Medical University, Ganzhou, China, Ganzhou, China (People's Republic), 9Department of Rheumatology, The First Hospital of Qiqihar, Qiqihar, China, Qiqihar, China (People's Republic), 10Department of Rheumatology, The Second Hopital of Anhui Medical University, Hefei, China, Hefei, China (People's Republic), 11Department of Rheumatology, The Second Affiliated Hospital of Nanchang University, Nanchang, China, Nanchang, China (People's Republic), 12Department of Rheumatology, Jiangxi Provincial People's Hospital, Nanchang, China, Nanchang, China (People's Republic)

    Background/Purpose: The GUARD (Genakumab in high Uric Acid-induced Arthritis/goutfor Resolution and Delay study) program was designed to investigate the efficacy and safety of Genakumab, a…
  • Abstract Number: 0280 • ACR Convergence 2024

    Trends in Management and Consultations for Gout: A Study of 18 Million Adults Using the OpenSAFELY Platform

    Mark Russell1, Jon Massey2, Edward Roddy3, Brian MacKenna4, Seb Bacon4, Ben Goldacre4, Colm Andrews4, George Hickman4, Amir Mehrkar2, Arti Mahto5, Andrew Rutherford6, Samir Patel1, Maryam Adas7, Edward Alveyn7, deepak Nagra1, Katie Bechman7, Joanna Ledingham8, Joanna Hudson9, Sam Norton1, Andrew Cope7 and James Galloway10, 1King's College London, London, England, United Kingdom, 2University of Oxford, Oxford, England, United Kingdom, 3Keele University, Keele, England, United Kingdom, 4University of Oxford, Oxford, United Kingdom, 5King's College Hospital NHS Foundation Trust, London, United Kingdom, 6King's College Hospital NHS Foundation Trust, London, England, United Kingdom, 7King's College London, London, United Kingdom, 8Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom, 9King's College London, King's College London, United Kingdom, 10Centre for Rheumatic Diseases, King's College London, London, United Kingdom

    Background/Purpose: Data from before the COVID-19 pandemic had shown persistently poor care for people with gout in many countries worldwide. Whether this was further exacerbated…
  • Abstract Number: 0283 • ACR Convergence 2024

    Prophylaxis of Gout Flares in Patients with Renal Impairment: Dosing Adjustments with Colchicine Oral Solution Informed by a Pharmacokinetic Model

    Jaymin Shah, Elaine Chan and Dmitri Lissin, Scilex Holding Company, Palo Alto, CA

    Background/Purpose: Patients receiving colchicine for prophylaxis of gout flares are at risk for dose-related gastrointestinal toxicity (nausea, vomiting, diarrhea, abdominal pain) if they have pre-existing…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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