ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 2159

Autoimmune Diseases in Catalonia: A Population Based Study Using a Public Big Data Program

Antoni Sisó-Almirall1,2,3, Belchin Kostov1,2,3, Elisenda Martínez Carbonell4, Soledad Retamozo5,6,7, Alejandra Flores-Chavez8,9,10, S. González-Martínez1,2,3, Pilar Brito-Zerón5, Antoni Dedéu Baraldés11, Jaume Benavent Àreu1,2,3 and Manuel Ramos-Casals2,12, 1Consorci d’Atenció Primària de Salut Barcelona Esquerre (CAPSBE), Barcelona, Spain, 2Departament de Medicina, Universitat de Barcelona, Barcelona, Spain, 3Grup de Recerca Transversal en Atenció Primària, IDIBAPS, Barcelona, Barcelona, Spain, 4Agency for Health Quality and Assessment of Catalonia (AQuAS). Ministry of Health, Catalonia., Barcelona, Spain, 5Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona, Barcelona, Spain, 6Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas (INICSA-UNC-CONICET), Cordoba, Argentina, 7Rheumatology Unit, Hospital Privado Universitario de Córdoba, Institute University of Biomedical Sciences University of Córdoba (IUCBC), Cordoba, Argentina, 8Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona, Spain., Barcelona, Spain, 9Unidad de Investigación Biomédica 02, Unidad de Investigación en Epidemiología Clínica, Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Hospital de Especialidades, Guadalajara, Guadalajara, Mexico, 10Programa de Doctorado en Ciencias Médicas, Centro Universitario de Investigaciones Biomédicas (CUIB), Universidad de Colima, Colima, Mexico, Mexico, Mexico, 11Agency for Health Quality and Assessment of Catalonia (AQuAS). Ministry of Health, Catalonia, Barcelona, Spain, 12Department of Autoimmune Diseases, ICMiD, Hospital Clínic Barcelona., Barcelona, Spain

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords: ,

Session Information

Date: Tuesday, October 23, 2018

Title: Epidemiology and Public Health Poster III: SLE, SSc, APS, PsA, and Other Rheumatic Diseases

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: To analyse the prevalence of autoimmune diseases (ADs) in Catalonia by using a public big data program (Public Data Analysis for Health Research and Innovation Program, PADRIS)

Methods: We used the health insurance database of the Catalan National Health Insurance (CNHI) which includes all catalan insured population in 2016 (7,483,761 inhabitants). ADs were identified according to the corresponding International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. A total of 33 autoimmune diseases were analysed classified in 4 main categories: rheumatic, systemic, organ-specific and immunodeficiency/autoinflammatory. The prevalence of ADs was calculated as the number of ADs patients divided by the total CNHI beneficiaries in the same year (rate per 100,000 persons, 95% confidence intervals -CI-).

Results: In Catalonia, the overall prevalence of ADs was 1,202 per 100,000 persons (95%CI 1,194-1,209); the prevalence was 1,455 (95%CI 1,443-1,467) in women and 939 (95%CI 929-949) in men. ADs were identified as organ-specific (43%), systemic (33%), rheumatic (23%) and immunodeficiency/autoinflammatory (1%) autoimmune diseases. The Top Ten of ADs with the highest prevalence rates included cutaneous psoriasis (282 cases per 100,000), rheumatoid arthritis (178 cases per 100,000), polymyalgia rheumatic (98 cases per 100,000), spondyloarthropathies (92 cases per 100,000), vasculitis (91 cases per 100,000), systemic lupus erythematosus (68 cases per 100,000), Sjšgren’s syndrome (59 cases per 100,000), celiac disease (58 cases per 100,000), multiple sclerosis (57 cases per 100,000) and psoriatic arthritis (43 cases per 100,000). In 26 (79%) of the 33 ADs, the female:male ratio was higher than 1; the highest ratios were reported for Sjšgren’s syndrome (10.5), primary biliary cholangitis (5.8), SLE (5.4), systemic sclerosis (3.4) and rheumatoid arthritis (2.6). We found a significant geographical variation in the prevalence of the main diseases (Figure 1).

Conclusion: Nearly 90,000 catalans are classified as having an autoimmune disease, representing a prevalence of 1.2% of the total population in Catalonia, a rate that reaches 1.5% in women. We found a different territorial distribution of the main diseases, suggesting a significant influence of geographically-driven determinants in the prevalence of autoimmune diseases.


Figure 1.

Disclosure: A. Sisó-Almirall, None; B. Kostov, None; E. Martínez Carbonell, None; S. Retamozo, None; A. Flores-Chavez, None; S. González-Martínez, None; P. Brito-Zerón, None; A. Dedéu Baraldés, None; J. Benavent Àreu, None; M. Ramos-Casals, None.

To cite this abstract in AMA style:

Sisó-Almirall A, Kostov B, Martínez Carbonell E, Retamozo S, Flores-Chavez A, González-Martínez S, Brito-Zerón P, Dedéu Baraldés A, Benavent Àreu J, Ramos-Casals M. Autoimmune Diseases in Catalonia: A Population Based Study Using a Public Big Data Program [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 9). https://acrabstracts.org/abstract/autoimmune-diseases-in-catalonia-a-population-based-study-using-a-public-big-data-program/. Accessed .

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