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  • Abstract Number: 1442 • ACR Convergence 2024

    Relationship Between Degenerative Lesions over Time in Axial Spondyloarthritis: 10-year Follow-up of the DESIR Cohort

    Laura Pina Vegas1, Floris van Gaalen2, Miranda van Lunteren3, Damien Loeuille4, Caroline Morizot5, Esther Newsum6, Pascal Claudepierre7, Alain SARAUX8, Antoine Feydy9, Monique Reijnierse1, Desiree van der Heijde10 and Sofia Ramiro11, 1Leiden University Medical Center, Leiden, Netherlands, 2LUMC, Leiden, Zuid-Holland, Netherlands, 3Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 4Phd, Nancy Vandoeuvre, Lorraine, France, 5Nancy University hospital, Nancy, France, 6Nij Smellinghe, Drachten, Netherlands, 7CHU Henri Mondor, AP-HP/EpiDermE, UPEC, Créteil, France, 8CHU Brest, Brest, France, 9CHU Cochin, AP-HP, Paris, France, 10Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 11Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Spinal degenerative lesions (DLs) are commonly seen/reported in radiographs and MRI in axSpA. However, the relationship between the different DLs over time has not…
  • Abstract Number: 1442 • ACR Convergence 2023

    Incident Vascular Events in Danish Nationwide Cohort of Patients with Newly Diagnosed Systemic Lupus Erythematosus

    Renata Baronaite Hansen1, Julia Simard2, Mikkel Faurschou1 and Søren Jacobsen3, 1Copenhagen Research Center for Autoimmune Connective Tissue Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, 2Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, 3Copenhagen Research Center for Autoimmune Connective Tissue Diseases, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

    Background/Purpose: Awareness of comorbidity in patients with SLE is increasing. Most studies to date have described comorbidity burden in prevalent SLE. We estimated the incidence…
  • Abstract Number: 1442 • ACR Convergence 2022

    Role of Platelet-bound Complement Activation Product (PC4d) in Predicting Risk of Future Thrombotic Events in Systemic Lupus Erythematosus

    Anca Askanase1, John Conklin2, Michelle Petri3, Vasileios Kyttaris4, Yevgeniya Gartshteyn5, Wei Tang1, Anja Kammesheidt6 and Roberta Alexander2, 1Columbia University Medical Center, New York, NY, 2Exagen, Inc., Vista, CA, 3Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, 4Beth Israel Deaconess Medical Center, Boston, MA, 5Columbia University Medical Center, Glen Rock, NJ, 6self, Laguna Beach, CA

    Background/Purpose: Platelet-bound complement activation products (PC4d) are associated with a history of thrombosis in systemic lupus erythematosus (SLE) (Gartshteyn al., 2021; Petri et al., 2017).…
  • Abstract Number: 1442 • ACR Convergence 2021

    Effectiveness of Cycling JAKi Compared to Switching to bDMARD in Patients Who Failed a First JAKi in an International Collaboration of Registries of Rheumatoid Arthritis Patients (the JAK-pot Study)

    Manuel Pombo-Suarez1, Carlos Sanchez-Piedra2, Juan J Gomez-Reino3, Kim Lauper4, Nevsun Inanc5, Anja Strangfeld6, Doreen Huschek7, Karel Pavelka8, Eirik Kristianslund9, Tore Kvien10, Ziga Rotar11, Dan Nordström12, Denis Choquette13, Ori Elkayam14, Burkhard Leeb15, Maria José Santos16, Kimme Hyrich17, Lianne Kearsley-Fleet18, Catalin Codreanu19, Denis Monguin20, Delphine Courvoisier20 and Axel Finckh21, 1Rheumatology Service, Hospital Clinico Universitario, Santiago De Compostela, Santiago de Compostela, Spain, 2Research Unit, Spanish Society of Rheumatology, Madrid, Spain, 3Hospital Clínico Universitario, Santiago de Compostela, Spain, 4Geneva University Hospitals, Geneve, Switzerland, 5Division of Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 6Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, 7Epidemiology and Health Services Research, German Rheumatism Research Center, Berlin, Germany, Berlin, Germany, 8Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 9Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, 10Diakonhjemmet Hospital, Oslo, Norway, 11Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia, 12Division of Internal Medicine and Rheumatology, Helsinki University Hospital, Helsinki, Finland, 13Institut de Rhumatologie de Montréal, Montréal, QC, Canada, 14Tel Aviv Medical Center, Tel Aviv, Israel, 15Karl Landsteiner University for Health Sciences, Krems/Donau, Karl Landsteiner Institute for Clinical Rheumatology, Hollabrunn, Austria, 16Rheumatology Department, Hospital Garcia de Orta, Almada, Portugal, 17University of Manchester, Manchester, United Kingdom, 18Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 19Center of Rheumatic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania, 20Division of Rheumatology, Geneva University Hospital, Geneva, Switzerland, 21University Hospital of Geneva, Geneve - Vesenaz, Switzerland

    Background/Purpose: With the arrival of new Janus kinase inhibitors (JAKi), with different JAK inhibition profiles, there is the possibility of using a second JAKi in…
  • Abstract Number: 1442 • ACR Convergence 2020

    Denosumab versus Oral Bisphosphonate for Osteoporosis in Long-term Glucocorticoid Users: A 12-month Randomized Controlled Trial

    Chi Chiu Mok1, Ling Yin Ho1 and Kwok Man Ma1, 1Tuen Mun Hospital, Hong Kong, China (People's Republic)

    Background/Purpose: To compare the efficacy of denosumab (DEN) and oral alendronate (ALN) on spinal bone mineral density (BMD) in long-term glucocorticoid users.Methods: Patients receiving long-term…
  • Abstract Number: 1442 • 2019 ACR/ARP Annual Meeting

    Comparison of Sustained Clinical Remission And/or Low Disease Activity Rate Between Rapidly and Gradually De-escalation of Abatacept in Rheumatoid Arthritis

    MASAOMI YAMASAKI1, 1Shin-Yokohama Arthritis and Rheumatology Clinic, Yokohama, Japan

    Background/Purpose: However biological DMARDs (bDMARDs) and treatment strategies have improved the outcomes of rheumatoid arthritis (RA), it is unknown who can taper or stop bDMARDs…
  • Abstract Number: 1442 • 2018 ACR/ARHP Annual Meeting

    Differential Chemical Isotope Labeling Liquid Chromatography Mass Spectrometry and a Universal Metabolome Standard Reveals a Metabolome Profile with Consistent Accuracy for Rheumatoid Arthritis

    Walter P. Maksymowych1, Xiaohang Wang2, Joel Paschke1, Rana Dadashova1, Edna Hutchings1 and Liang Li2, 1CaRE Arthritis, Edmonton, AB, Canada, 2Chemistry, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Early diagnosis of rheumatoid arthritis (RA) is hampered by suboptimal accuracy of currently available serological biomarkers. Recent advancements in metabolomic profiling include dansylation liquid…
  • Abstract Number: 1442 • 2017 ACR/ARHP Annual Meeting

    Corticosteroid Sparing Effect of Non-TNF Targeted Biologics, Rituximab, Abatacept and Tocilizumab in Common Practice: Data from 3183 Patients Enrolled in the French Society of Rheumatology Registries

    Jacques-Eric Gottenberg1, Jacques Morel2, Arnaud Constantin3, Thomas Bardin4, Alain Cantagrel5, Bernard Combe2, Maxime Dougados6, René-Marc Flipo7, Alain Saraux8, Thierry Schaeverbeke9, Jean Sibilia10, Martin Soubrier11, Olivier Vittecoq12,13, Gabriel Baron14, Elodie Perrodeau15, Philippe Ravaud14 and Xavier Mariette16, 1CNRS, Immunopathologie et Chimie Thérapeutique/Laboratory of Excellence Medalis, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France, 2Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 3Rheumatology, CHU Purpan - Hopital Pierre-Paul Riquet, Toulouse, France, 4Clinique de Rhumatologie, Hopital Lariboisiere, Paris Cedex 10, France, 5Department of Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, Toulouse, France, 6Rheumatology, Paris Descartes University, Paris, France, 7Rheumatology, Department of Rheumatology, CHU Teaching Hospital Lille, France., Lille, France, 8Rheumatology, Brest University Hospital, Brest, France, 9Department of Rheumatology, Bordeaux University Hospital, BORDEAUX, France, 10Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, 11Rheumatology, Department of Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, 12INSERM U905 & Normandy University, Institute for Research and Innovation in Biomedicine, Rouen, France, 13Rheumatology Department and INSERM U 905, CHU Rouen, Rouen, France, 14Hôpital Hôtel Dieu, Paris, France, 15Epidemiology, Hopital Hotel Dieu, Paris Descartes University, Paris, France, 16Université Paris-Sud, AP-HP, Hôpitaux Universitaires Paris-Sud, Paris, France

    Background/Purpose: Little is known regarding the corticosteroid sparing effect of non-TNF biologics in rheumatoid arthritis (RA). Objectives : To compare the corticosteroid sparing effect of…
  • Abstract Number: 1442 • 2016 ACR/ARHP Annual Meeting

    Suppression of Acute Arthritis By N-Methyl-3,4-Dichloropropionaniline (N-MeDCPA), a Reversible Orai Calcium Channel Inhibitor

    John Barnett1, Lisa Robinson2, Jonathan Soboloff3, Rosana Schafer4, Ida Holaskova5, Meenal Elliott1, Michelle Witt2, Raphael Hirsch6 and Harry Blair7, 1Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV, 2Pathology, West Virginia University, Morgantown, WV, 3Dept of Medical Genetics and Molecular Biochemistry, Temple University, Philadelphia, PA, 4Dept Micro, Immun & Cell Biol, West Virginia University, Morgantown, WV, 5West Virginia University, Morgantown, WV, 6Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, 7pathology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:  Bone maintenance is a balance between the removal of old bone by osteoclasts (OCL) and the production of new bone by osteoblasts. In the…
  • Abstract Number: 1442 • 2015 ACR/ARHP Annual Meeting

    Descriptive Characteristics of Patients Prescribed Opioids for the Treatment of Chronic Pain

    Jenna Goesling1, Stephanie Moser2, Afton L. Hassett3, Chad Brummett1 and Natalie Gulau1, 1Anesthesiology, University of Michigan, Ann Arbor, MI, 2Department of Anesthesiology, University of Michigan, Ann Arbor, MI, 3Anesthesiology, University of Michigan Medical School, Ann Arbor, MI

    Background/Purpose: Opioids remain the cornerstone of acute pain therapy. However, there is little empirical evidence supporting the use of long-term opioid therapy for chronic pain.…
  • Abstract Number: 1442 • 2014 ACR/ARHP Annual Meeting

    The 2013 ACC/AHA Cardiovascular Risk Prediction Model and Coronary Atherosclerosis in Patients with Rheumatoid Arthritis

    Vivian K. Kawai1, Cecilia P. Chung2, Joseph F. Solus1, Annette Oeser1, Paolo Raggi3 and C. Michael Stein1, 1Vanderbilt University, Nashville, TN, 2Medicine, Vanderbilt University, Nashville, TN, 3University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Patients with rheumatoid arthritis (RA) have increased risk of atherosclerotic cardiovascular (CV) disease  that is underestimated by the Framingham risk score (FRS). We hypothesized…
  • Abstract Number: 1442 • 2013 ACR/ARHP Annual Meeting

    Three-Year Drug Survival and Effectiveness Of Abatacept and Tocilizumab In Patients with  Rheumatoid Arthritis Treated In Routine Care. Results From The Nationwide Danish Danbio Registry

    HCB Leffers1,2, Mikkel Østergaard3, Bente Glintborg4, Niels Steen Krogh5, Ulrik Tarp6, Tove Lorenzen7, Annette Hansen8, Lene Dreyer9 and Merete L. Hetland3, 1DANBIO, On behalf of Depts of Rheumatology, North, South, Central, Zealand and Capital Region, Glostrup, Denmark, 2Department of Rheumatology, Frederiksberg Hospital, Frderiksberg, Denmark, 3Copenhagen University Hospital Glostrup, Copenhagen, Denmark, 4Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, 5ZiteLab ApS, Copenhagen, Denmark, 6Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 7Department of Rheumatology, Region Hospital Silkeborg, Silkeborg, Denmark, 8Department of Rheumatology, Gentofte University Hospital, Copenhagen, Denmark, 9Internal Medicine - Rheumatology Section, Copenhagen University Hospital at Gentofte, Copenhagen, Denmark

    Background/Purpose: Treatment with abatacept and tocilizumab has been shown to be efficacious in rheumatoid arthritis (RA) patients refractory to tumor necrosis factor inhibitor (TNFi). However,…
  • Abstract Number: 1442 • 2012 ACR/ARHP Annual Meeting

    IRF-1 Deficient Lupus-Prone MRL/Lpr Mice Show Reduced Glomerulonephritis but Develop Severe Interstitial Nephritis, Renal Vasculitis and Pulmonary Granulomas with Propensity for Th2 Polarity

    Hidemaru Sekine1, Takeshi Machida1, Natsumi Sakamoto1, Eiji Suzuki2, Xian Zhang3, Christopher Reilly4 and Gary S. Gilkeson5, 1Immunology, Fukushima Medical University School of Medicine, Fukushima, Japan, 2Medicine, Medical University of South Carolina, Charleston, SC, 3Medicine, Medical University of South Carolina and Ralph H. Johnson VA Medical Center, Charleston, SC, 4Virginia Tech, Blacksburg, VA, 5Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC

    Background/Purpose: The transcription factor interferon regulatory factor-4 (IRF-4) and -1 (IRF-1) are members of the IRF family of transcription regulators and involved in the development…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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