Abstracts tagged "X-ray"

Abstract Number: 0687 • ACR Convergence 2020
Musculoskeletal Manifestations in Patients with CD73 Deficiency
Cornelia Cudrici¹, Kam Newman², Deepak Lakshmipathy¹, Elisa Ferrante¹, Rebecca Huffstutler¹, Katherine Carney¹, Blas Betancourt², Markku Miettinen³, James Katz⁴, Leon Nesti⁵, Han Wen¹, Manfred Boehm⁶ and Alessandra Brofferio¹, ¹National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ³National Cancer Institute, National Institutes of Health, Bethesda, MD, ⁴NIH NIAMS, Bethesda, MD, ⁵Clinical and Experimental Orthopaedics, Walter Reed National Military Medical Center, Bethesda, MD, ⁶Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
Background/Purpose: Arterial calcification due to deficiency of CD73 (ACDC) is a hereditary autosomal recessive ectopic mineralization syndrome caused by loss-of-function mutations in the 5'-nucleotidase Ecto…
Abstract Number: 0708 • ACR Convergence 2020
Differences in Treating Knee Osteoarthritis by Clinician Specialty
Denise Baldock¹ and Casey Zhang², ¹Ipsos MORI, London, England, United Kingdom, ²Ipsos Insight, New York, NY
Background/Purpose: Current treatment of knee osteoarthritis (OA) is focused primarily around pain relief offering sustained mobility and prioritizing symptom relief over disease progression potentially impacts…
Abstract Number: 0760 • ACR Convergence 2020
X-rays Bone Erosions Are Uncommon in Anti-CCP Positive Individuals At-risk of Rheumatoid Arthritis with Musculoskeletal Symptoms Without Clinical Synovitis, and Do Not Predict the Development of Inflammatory Arthritis
Andrea Di Matteo¹, Kulveer Mankia¹, Jacqueline L Nam¹, Edoardo Cipolletta², Leticia Garcia-Montoya³, Laurence Duquenne¹, Emma Rowbotham⁴ and Paul Emery⁵, ¹University of Leeds and Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ²Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi (AN), Italy, ³The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom, ⁴Department of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom
Background/Purpose: In individuals at-risk of RA, the identification of reliable biomarkers for the future development of clinical arthritis is of critical importance for risk-stratification and…
Abstract Number: 1114 • ACR Convergence 2020
Longitudinally Assessed Structural Abnormalities on MRI and Relative Contributions to Risk of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up
C. Kent Kwoh¹, Ali Guermazi², Erin Ashbeck³, Chengcheng Hu³, Edward Bedrick³, Leena Sharma⁴, Charles Eaton⁵, Marc Hochberg⁶, Rebecca Jackson⁷, Timothy McAlindon⁸, Michael Nevitt⁹, Jane Cauley¹⁰ and Frank Roemer¹¹, ¹University of Arizona of Arizona Arthritis Center and Division of Rheumatology, College of Medicine, University of Arizona, Tucson, AZ, ²Boston University School of Medicine, Boston, MA, ³University of Arizona, Tucson, AZ, ⁴Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Family Medicine and Epidemiology, Warren Alpert Medical School of Brown University,Department of Epidemiology, School of Public Health of Brown University, Providence, RI, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷Ohio State University, Columbus, OH, ⁸Tufts Medical Center, Boston, MA, ⁹University of California, San Francisco, San Francisco, CA, ¹⁰University of Pittsburgh, Pittsburgh, PA, ¹¹Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany
Background/Purpose: MRI has identified joint tissues affected during knee OA development, though the relative importance of structures in the pathogenic process is unknown. Our objective…
Abstract Number: 1541 • ACR Convergence 2020
Ultrasound in Knee Osteoarthritis: Reader Performance, Sonographic Features, and Correlation with Radiographic Findings
Ogonna Nwawka¹, Susan Lee¹, Bin Lin², Said Ibrahim³, Collin Brantner⁴, Peter Sculco⁵, Michael Parks¹, Mark Figgie⁶, Laura Donlin¹, Dana Orange⁷, Serene Mirza², Michael Cross¹, Jose Rodriguez¹, Thomas Sculco¹, Miguel Otero², William Robinson⁸, Susan Goodman⁶ and Bella Mehta⁵, ¹Hospital for Special Surgery, Weill Cornell Medicine, New York, ²Hospital for Special Surgery, New York, ³Weill Cornell Medicine, Cleveland, OH, ⁴Hospital for Special Surgery, New York, NY, ⁵Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁶Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ⁷Rockefeller University, New York, ⁸Stanford University, Palo Alto, CA
Background/Purpose: Radiography is the most widespread imaging technique used in the evaluation of knee osteoarthritis (KOA), and MRI is known to be specific in characterization…
Abstract Number: 1545 • ACR Convergence 2020
An Artificial Intelligence (AI) Assistant Identifying Spinal Diffuse Idiopathic Skeletal Hyperostosis on Plain X-rays: A Pilot Deep Learning Study
Sarah Ringsted¹, Nishad Sathe¹, Atul Deodhar² and Dongseok Choi², ¹Oregon Health and Science University, Portland, OR, ²Oregon Health & Science University, Portland, OR
Background/Purpose: Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition most classically seen in the spine, and is characterized by ossification of the spinal ligaments…
Abstract Number: 1546 • ACR Convergence 2020
Ultrasound, Magnetic Resonance Imaging and Radiography of the Fingers’ Joints of Psoriatic Arthritis Patients
Ari Polachek¹, Victoria Furer², Mirna Zureik³, Sharon Nevo³, Liran Mendel⁴, David Levartovsky², Jonathan Wollman⁴, Valerie Aloush², Reut Tzemach⁴, Ofir Elalouf⁵, Marina Anouk⁶, Mark Berman², Ilana Kaufman⁷, Yael Lahat goldstein², Hagit Sarbagil-Maman⁸, Sara Borok Lev-Ran², Adi Broide³, Lihi Eder⁹, Daphna Paran², Moshe Iluz¹⁰, Iris Eshed¹¹ and Ori Elkayam³, ¹Tel Aviv Sourasky Medical Center, Petah-Tikva, Israel, ²Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ³Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel, ⁴Souraaky Medical Center, Tel-Aviv, Israel, ⁵Souraaky Medical Center, Herzliya, Israel, ⁶Souraaky Medical Center, Tel Aviv, Israel, ⁷Tel Aviv Sourasky Medical Center, Petah-Tiqwa, Israel, ⁸Tel-Aviv Sourasky Medical Center, Kiryat Ono, Israel, ⁹University of Toronto, Toronto, ON, Canada, ¹⁰Souraaky Medical Center, Tel-Aviv, ¹¹Sheba Medical Center, Tel-Aviv, Israel
Background/Purpose: Ultrasound (US), magnetic resonance imaging (MRI) and conventional radiography are the leading imaging modalities for musculoskeletal (MSK) assessment in PsA. However, little is reported…
Abstract Number: 1561 • ACR Convergence 2020
Findings Compatible with Axial Spondyloarthritis in Radiologist Reports
Rouhin Sen¹, Emmeline Kim², Evan Manning³, Eric Anderson⁴, Kyle Maier⁵, Elizabeth Cheng⁶ and Liron Caplan⁶, ¹University of Colorado - Division of Rheumatology, Denver, CO, ²University of Colorado School of Medicine, Denver, ³University of Colorado - Department of Medicine, Denver, ⁴Washington University - Division of Rheumatology, St. Louis, ⁵United States Air Force, San Antonio, TX, ⁶Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO
Background/Purpose: The sacroiliac joint (SIJ) has a distinct anatomical shape that can pose challenges to standard planar imaging techniques making the detection of subtle changes…
Abstract Number: 1644 • ACR Convergence 2020
Radiographic Exclusionary Findings During Screening for Three Phase III Trials of Subcutaneous Tanezumab in Patients with Moderate to Severe Hip or Knee Osteoarthritis
Ali Guermazi¹, Frank Roemer², Andrew Kompel¹, Luis Diaz³, Michel Crema⁴, Mark Brown⁵, Anne Hickman⁵, Glenn Pixton⁶, Lars Viktrup⁷, Robert Fountaine⁵, Aimee Burr⁵, Sarah Sherlock⁵ and Christine West⁸, ¹Boston University School of Medicine, Boston, MA, ²Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany, ³Boston Veteran Affairs Healthcare System, Boston, MA, ⁴Boston University School of Medicine, Paris, France, ⁵Pfizer Inc., Groton, CT, ⁶Pfizer Inc., Morrisville, NC, ⁷Eli Lilly and Company, Indianapolis, IN, ⁸Pfizer Inc, Groton, CT
Background/Purpose: Tanezumab is a nerve growth factor monoclonal antibody in development for osteoarthritis (OA). Following a clinical hold due to concerns around adverse joint events,…
Abstract Number: 1730 • ACR Convergence 2020
Comparison of MBDA Score, Patient Global Assessment and Evaluator Global Assessment for Predicting Risk of Radiographic Progression
Leonard Calabrese¹, Michael Weinblatt², Nancy Shadick², Cecilie Hegaard Brahe³, Mikkel Østergaard⁴, Merete Hetland⁵, Megan Horton⁶, Darl Flake⁶ and Eric Sasso⁷, ¹Cleveland Clinic, Cleveland, OH, ²Brigham and Women's Hospital, Boston, MA, ³Center for Rheumatology and Spine diseases, Glostrup, Denmark, ⁴Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁵The DANBIO Registry, Rigshospitalet, Glostrup, Denmark, ⁶Myriad Genetics, Inc., Salt Lake City, UT, ⁷Myriad Autoimmune, South San Francisco, CA
Background/Purpose: To compare the abilities of MBDA score, patient global assessment (PGA) and evaluator global assessment (EGA) to assess risk for radiographic progression (RP), and…

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