ACR Meeting Abstracts

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Abstracts tagged "X-ray"

  • Abstract Number: 0820 • ACR Convergence 2023

    Radiographic and Pain Outcomes from a Phase 3 Extension Study Evaluating the Safety and Efficacy of Lorecivivint in Subjects with Severe Osteoarthritis of the Knee (OA-07): 36 Month Single Blind and Placebo Crossover Phase Results

    Yusuf Yazici1, Christopher Swearingen2, Victor Lopez3, Jon Britt4, Sarah Kennedy5, Jeyanesh Tambiah2 and Timothy McAlindon6, 1NYU Grossman School of Medicine, La Jolla, CA, 2Biosplice Therapeutics, Inc., San Diego, CA, 3Biosplice Therapeutics, Inc., Santa Clarita, CA, 4Biosplice Therapeutics, Inc., Los Angeles, CA, 5Biosplice Therapeutics, Inc., Superior, CO, 6Tufts Medical Center, Arlington, MA

    Background/Purpose: Knee osteoarthritis (OA) has unmet need for safe, efficacious symptom and disease-modifying treatments. Lorecivivint (LOR), an intra-articular (IA) CLK/DYRK inhibitor thought to modulate Wnt…
  • Abstract Number: 0992 • ACR Convergence 2023

    Association Between Metabolic Syndrome and the Presence of Enthesophytes on Musculoskeletal Ultrasound Compared to Joint X-ray

    Sean Brown1, John Hardin2 and Shereen Mahmood3, 1Montefiore Medical Center, Bronx, NY, 2Albert Einstein College of Medicine, Bronx, NY, 3Albert Einstein College of Medicine / Montefiore Medical Center, New York, NY

    Background/Purpose: Enthesophytes consist of calcium deposition on tendons or ligaments that are proposed to form in response to localized inflammation of the enthesis, either idiopathic…
  • Abstract Number: 1038 • ACR Convergence 2023

    Improved Assessment of Structural Damage in the Spine in Patients with Axial Spondyloarthritis by MRI-based Synthetic CT: A Comparison with Low-dose CT and X-ray

    Simone Tromborg Willesen1, Nora Vladimirova1, Jakob Moeller2, Anna Enevold Fløistrup Hadsbjerg1, Bimal Mayur Kumar Vora3, Sengul Seven1, Susanne Juhl Pedersen1 and Mikkel Østergaard1, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 2Herlev-Gentofte Hospital, Herlev, Denmark, 3Singapore General Hospital, Singapore, Singapore

    Background/Purpose: Whether a therapy has bone structure-modifying effects in the spine is crucial to determine since this is a prerequisite for a therapy to reduce…
  • Abstract Number: 1289 • ACR Convergence 2023

    Increases in Serum Levels of Tartrate-Resistant Acid Phosphatase 5b Reflected Radiographic Progression of Joint Damage in Treated Rheumatoid Arthritis

    Takayoshi Owada1, Takayuki Kobayashi1, Ayae Tanaka2, Kei Ikeda2, Hirokuni Hirata1, Masafumi Arima3, Kazuhiro Kurasawa2 and Yasutsugu Fukushima1, 1Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan, 2Dokkyo Medical University, Mibu-machi, Shimotsuga-gun, Japan, 3Dokkyo Medical University, Koshigaya, Japan

    Background/Purpose: Rheumatoid Arthritis (RA) is one of inflammatory arthritis, and this autoimmune-mediated polyarthritis results in structural joint destruction. Articular bone erosion leading to joint destruction in RA…
  • Abstract Number: 1310 • ACR Convergence 2023

    Comparison of Two Methotrexate Initiation Strategies in Rheumatoid Arthritis in Current Practice

    Paola Vidal-Montal1, Alice Combier2, Alexia STEELANDT2, Marion THOMAS2, Javier Narvaez3, Joan Miquel Nolla1, Yannick ALLANORE4 and Jerome AVOUAC5, 1Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, 3Hospital Universitario de Bellvitge, Barcelona, Spain, 4Université Paris Cité, Paris, France, 5Rheumatology A Department, Hôpital Cochin, AP-HP Centre - Université Paris Cité, Paris, France

    Background/Purpose: To compare the efficacy and tolerance at 3 and 6 months of two methotrexate (MTX) initiation strategies in rheumatoid arthritis (RA). Methods: Retrospective,monocentric,cross-sectionalstudy including…
  • Abstract Number: 1353 • ACR Convergence 2023

    Sexual Dysfunction in Women with Systemic Lupus Erythematosus: A Cross-Sectional Multicentre Study

    Maria Helena Lourenco1, Rita Torres2, Santiago Rodrigues-Manica3, Vanessa Fraga4, Ana Catarina Abreu5, Roberto Costa6, Carolina Ochôa Matos7, Beatriz Mendes8, Beatriz Samões9, Inês Silva1, Fernando Pimentel-Santos10, Manuela Costa1, Jaime Branco11 and Alexandre Sepriano12, 1Hospital Egas Moniz, Lisbon, Portugal, 2Hospital Egas Moniz, Lisboa, Portugal, 3Hospital Egas Moniz, CHLO, Lisboa, Portugal, 4Hospital Garcia de Orta, Nogueira da Regedoura, Portugal, 5Hospital Garcia de Orta, Lisboa, Portugal, 6Centro Hospitalar Lisboa Norte, Lisboa, Portugal, 7Centro Académico de Medicina de Lisboa, Lisbon, Portugal, 8Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 9Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal, 10NOVA Medical School; Universidade NOVA e Lisboa, Lisboa, Portugal, 11CHLO, EPE - Hospital Egas Moniz, Lisbon, Portugal, 12Leiden University Medical Centre, Portela Loures, Portugal

    Background/Purpose: Due to its multisystemic involvement, systemic lupus erythematosus (SLE) can have a significant impact on patients' quality of life (QoL). Sexual (dis)function is a…
  • Abstract Number: 1401 • ACR Convergence 2023

    The Association of 3VAS/4VAS and DAPSA with Radiographic Progression in Early PsA

    Gonul Hazal Koc1, Marc r. Kok2, Jolanda J. Luime1, ilja Tchetverikov3, William R Tillett4, Fazira R. Kasiem1, Lindy A. Korswagen5, J. Bijsterbosch6, Yvonne P. M. Goekoop-Ruiterman7, Maikel van oosterhout8, P. Baudoin9, Petra Kok10, radboud J.e.m. Dolhain11 and marijn vis1, 1Erasmus Medical Center, Rotterdam, Netherlands, 2Maasstad Hospital, Rotterdam, Netherlands, 3Albert Sweitzer Hospital, Dordrecht, Netherlands, 4Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 5Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands, 6Amphia Hospital, Rotterdam, Netherlands, 7Haga Ziekenhuis, The Hague, Netherlands, 8Groene Hart Ziekenhuis, Gouda, Netherlands, 9Reumazorg Zuid West Nederland, Roosendaal, Netherlands, 10Reinier de Graaf Gasthuis, Delft, Netherlands, 11Rheumatology, Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: A feasible, widely accepted, comprehensive disease activity measure is needed for daily use in psoriatic arthritis (PsA). Current measures are either complex (Psoriatic Arthritis…
  • Abstract Number: 1555 • ACR Convergence 2023

    Axial Spondyloarthritis in Patients with Gastrointestinal Involvement of Behçet Syndrome

    Musab Ozturk1, Sinem Nihal Esatoglu2, Ibrahim Hatemi3, Aykut Ferhat Celik3, Osman Aykan Kargin4, Ahmet Oz4, Erkan Yilmaz5, Didar Ucar6, Melike Melikoglu2, Hasan Yazici7, Ibrahim Adaletli4 and Gulen Hatemi2, 1Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Istanbul, Turkey, 2Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 3Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Internal Medicine, Division of Gastroenterology, Istanbul, Turkey, 4Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Radiology, Istanbul, Turkey, 5Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Tissue Typing Laboratory, Istanbul, Turkey, 6Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Department of Ophthalmology, Istanbul, Turkey, 7Academic Hospital, Istanbul, Turkey

    Background/Purpose: Controlled studies have shown that radiographic sacroiliitis was not increased in Behçet syndrome (BS), compared to other inflammatory diseases. However, gastrointestinal involvement of Behçet…
  • Abstract Number: 1825 • ACR Convergence 2022

    Vascular Calcifications Adjacent to the Involved Joint of Patients Diagnosed with Calcium Pyrophosphate Crystal Arthritis – a Retrospective Observational Study

    Shay Brikman1, Amir Bieber2 and Reuven Mader1, 1Rheumatic Diseases Unit, Emek Medical Center, Afula, Israel, 2Emek Medical Center, Raanana, Israel

    Background/Purpose: Prior studies have shown an association between chondrocalcinosis (CC) and vascular calcifications. In this study, we aimed to assess the presence of vascular calcifications…
  • Abstract Number: 1901 • ACR Convergence 2022

    What Does Radiographic Minimum JSW Actually Measure? Comparison of Radiographic and MRI Measures Using Data from the OAI

    Alan Brett1, Michael Bowes2 and Philip G Conaghan3, 1Stryker, Austin, TX, 2Stryker, Manchester, United Kingdom, 3University of Leeds, Leeds, United Kingdom

    Background/Purpose: Change in radiographic joint space width (JSW) is used as a surrogate for cartilage loss and recognized by regulatory bodies as a measure of…
  • Abstract Number: 2011 • ACR Convergence 2022

    More Meticulously Following Treat-to-target in RA Does Not Lead to Less Radiographic Progression: A Longitudinal Analysis in BIODAM

    Sofia Ramiro1, Robert Landewé2, Désirée van der Heijde3, Alexandre Sepriano4, Oliver FitzGerald5, Mikkel Østergaard6, Joanne Homik7, Ori Elkayam8, Carter Thorne9, Maggie Larche10, Gianfranco Ferraccioli11, Marina Backhaus12, Gilles Boire13, Bernard Combe14, Thierry Schaeverbeke15, Alain Saraux16, Maxime Dougados17, Maurizio Rossini18, Marcello Govoni19, Luigi Sinigaglia20, Alain Cantagrel21, CF Allaart1, Cheryl Barnabe22, Clifton O. Bingham III23, Dirkjan van Schaardenburg24, HIlde Hammer25, Rana Dadashova26, Edna Hutchings26, Joel Paschke26 and Walter P Maksymowych27, 1Leiden University Medical Center, Leiden, Netherlands, 2Amsterdam University Medical Center, Meerssen, Netherlands, 3Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 4Leiden University Medical Centre, Portela Loures, Portugal, 5Conway Institute, University College Dublin, Dublin, Ireland, 6Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 7Division of Rheumatology, University of Alberta, Edmonton, AB, Canada, 8Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 9Southlake Regional Health Centre, Newmarket, ON, Canada, 10McMaster University, Hamilton, ON, Canada, 11Catholic University of the Sacred Heart, Rome, Roma, Italy, 12Park-Klinik Weissensee Academic Hospital of the Charité, Berlin, Germany, 13Universite de Sherbrooke, Sherbrooke, QC, Canada, 14CHU Montpellier and Montpellier University, Monpellier, France, 15FHU ACRONIM, University Hospital of Bordeaux, University of Bordeaux, Bordeaux, France, 16CHU Brest, Brest, France, 17Department of Rheumatology, Hôpital Cochin, Paris, France, Paris, France, 18Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy, 19S. Anna Hospital and University of Ferrara, Ferrara, Italy, 20Gaetano Pini Institute, Milano, Italy, 21CHU Toulouse, Paul Sabatier University, Toulouse, France, 22University of Calgary, Calgary, AB, Canada, 23Johns Hopkins University, Baltimore, MD, 24Amsterdam UMC, Amsterdam, Netherlands, 25Diakonhjemmet Hospital, Oslo, Oslo, Norway, 26CARE Arthritis LTD, Edmonton, AB, Canada, 27Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: A Treat-to-Target approach (T2T) is broadly considered to lead to better clinical outcomes and recommended in patients with RA. However, very few studies have…
  • Abstract Number: 2255 • ACR Convergence 2022

    Do Fatty Lesions Explain the Association Between Inflammation and New Syndesmophytes in Patients with Radiographic Axial Spondyloarthritis?

    Rosalinde Stal1, Alexandre Sepriano2, Sofia Ramiro1, floris van Gaalen1, Pedro Machado3, Xenofon Baraliakos4, Manouk de Hooge5, Rosaline van den Berg1, Monique Reijnierse1, Juergen Braun6, Robert Landewé7 and Désirée van der Heijde8, 1Leiden University Medical Center, Leiden, Netherlands, 2Leiden University Medical Centre, Portela Loures, Portugal, 3University College London, London, United Kingdom, 4Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 5Ghent University Hospital, Luxembourg, Luxembourg, 6Rheumazentrum Ruhrgebiet, Herne, Germany, 7Amsterdam University Medical Center, Meerssen, Netherlands, 8Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands

    Background/Purpose: Presence of vertebral corner inflammation (VCI) increases the likelihood of a new syndesmophyte in the same vertebral corner (VC) in patients with r-axSpA. It…
  • Abstract Number: 0307 • ACR Convergence 2022

    Reduction in Structural Damage Progression and Improvement in Clinical Response with Abatacept Treatment in Patients with ACPA+, Early RA: Results from a Post Hoc Analysis of the AVERT-2 Study by Baseline Erosion Scores

    Chahin Pachai1, Sean E Connolly2, Yoshiya Tanaka3, Vivian Bykerk4, Tom Huizinga5, Gustavo Citera6, Clifton O. Bingham III7, Shuyan Du1, Godehard Hoexter8, Roy Fleischmann9, Subhashis Banerjee1 and Paul Emery10, 1Bristol Myers Squibb, Princeton, NJ, 2Bristol-Myers Squibb, Morrisville, PA, 3University of Occupational and Environmental Health, Kitakyusyu Fukuoka, Japan, 4Hospital for Special Surgery, New York, NY, 5Leiden University Medical Center, Leiden, Netherlands, 6Instituto de Rehabilitación Psicofísica (IREP), Buenos Aires, Argentina, 7Johns Hopkins University, Baltimore, MD, 8Bristol Myers Squibb GmbH & Co. KGaA, Munich, Germany, 9University of Texas Southwestern Medical Center and Metroplex Clinical Research Center, Dallas, TX, 10Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Presence of structural damage is an important risk factor for further damage progression over time in RA. Inhibition of damage progression is a key…
  • Abstract Number: 0383 • ACR Convergence 2022

    Analysis of the Performance of an Artificial Intelligence Algorithm for the Detection of Radiographic Sacroiliitis in an Independent Cohort of axSpA Patients Including Both Nr-axSpA and r-axSpA

    Fabian Proft1, Janis Vahldiek2, Joeri Nicolaes3, Rachel Tham4, Bengt Hoepken5, Baran Ufuktepe6, Denis Poddubnyy1 and Keno Kyrill Bressem2, 1Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, Berlin, Germany, 3UCB Pharma, Anderlecht, Belgium, 4UCB Pharma, Slough, UK, Overland Park, KS, 5UCB Pharma, Monheim am Rhein, Germany, 6UCB Pharma A.S., Istanbul, Turkey

    Background/Purpose: Conventional radiography of the sacroiliac joints is the first imaging method if axial spondyloarthritis (axSpA) is suspected. The presence of definite radiographic sacroiliitis is…
  • Abstract Number: 0396 • ACR Convergence 2022

    Validity of Syndesmophyte Detection on Low Dose Computed Tomography in Patients with Radiographic Axial Spondyloarthritis

    Rosalinde Stal1, Sofia Ramiro1, Xenofon Baraliakos2, Juergen Braun3, Monique Reijnierse1, Rosaline van den Berg1, floris van Gaalen1 and Désirée van der Heijde4, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands

    Background/Purpose: Low-dose Computed Tomography (ldCT), assessed with the CT syndesmophyte score (CTSS) in the whole spine, has been shown to detect more progression in the…
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