Abstracts tagged "wnt5a"

Abstract Number: 1943 • ACR/ARP Annual Meeting 2019
The Emerging Regulatory Function of microRNA146a in Bone Biology and Osteoporosis
Victoria Saferding¹, Melanie Hofmann ², Julia S. Brunner ², Mihaela F. Militaru ², Antonia Puchner ², Silvia Hayer ², Melanie Timmen ³, Richard Stange ³, Josef Smolen ² and Stephan Blüml ⁴, ¹Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, ²Medical University of Vienna, Vienna, Austria, ³University Hospital Muenster, Muenster, Germany, ⁴Medical University of Vienna, Vienna
Background/Purpose: Micro RNAs (miRNAs) play a crucial role in the regulation of bone metabolism. MiR-146a, an important anti-inflammatory miRNA, was found to negatively impact osteogenesis…