Abstracts tagged "WNT Signaling and ankylosing spondylitis (AS)"

Abstract Number: 1672 • 2016 ACR/ARHP Annual Meeting
Microrna-29a Activation of Canonical Wnt Signaling By Targeting LRP6 in Ankylosing Spondylitis
Jinxian Huang¹, Zhihua Yin², Zhongchao Fu³, Zhizhong Ye³ and Lijun Zhang⁴, ¹Rheumatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China, ²Rheumatology, The Fourth People’s Hospital of Shenzhen, Shenzhen, China, ³The Fourth People’s Hospital of Shenzhen, Shenzhen, China, ⁴The University of Hong Kong-Shenzhen Hospital, Shenzhen, China
Background/Purpose: Aberrant regulation of the Wnt pathway is a key element in the pathogenesis of Ankylosing spondylitis (AS). We previously found that miR-29a was significantly…
Abstract Number: 603 • 2014 ACR/ARHP Annual Meeting
Periostin May Have a Role in Ankylosing Spondylitis and It Is Associated with Wnt Signalling Pathway Regulators
Servet Akar¹, Saadettin Uslu², Leyla Didem Kozaci³, Gercek Can⁴, Neslihan Karaca⁵, Emine Figen Tarhan⁴, Mustafa Ozmen⁶ and Dilek Solmaz⁷, ¹Department of Internal Medicine, Division of Rheumatology, Izmir Katip Celebi University School of Medicine,, Izmir, Turkey, ²Department of Internal Medicine, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, ³Department of Medical Biochemistry, Adnan Menderes University School of Medicine, Aydin, Turkey, ⁴Internal Medicine Clinic, Division of Rheumatology, Izmir Ataturk Education and Reseach Hospital, Izmir, Turkey, ⁵Adnan Menderes University, Science Thecnology Research and Application Center, Aydin, Turkey, ⁶Internal Medicine Clinic, D,v,s,on of Rheumatology, Izmir Ataturk Education and Reseach Hospital, Izmir, Turkey, ⁷Department of Internal Medicine, Division of Rheumatology, Namik Kemal University School of Medicine, Tekirdag, Turkey
Background/Purpose: Ankylosing spondylitis (AS) is a chronic rheumatic disease characterized by sacroiliac and spinal inflammationand new bone formation (syndesmophyte). Molecular mechanisms underlying this process have…

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