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Abstracts tagged "Wegener’s granulomatosis and rituximab"

  • Abstract Number: 1654 • ACR/ARHP Annual Meeting 2012

    Primary Endpoint Failure in the Rituximab in ANCA-Associated Vasculitis Trial

    Eli Miloslavsky1, Ulrich Specks2, John H. Stone3 and RAVE/ITN Research Group4, 1Division of Rheumatology, Massachusetts General Hopsital, Boston, MA, 2Mayo Clinic, Rochester, MN, 3Rheumatology, Massachusetts General Hospital, Boston, MA, 4Bethesda, MD

    Primary Endpoint Failure in the Rituximab in ANCA-associated Vasculitis TrialBackground/Purpose: The RAVE trial demonstrated that rituximab (RTX) is non-inferior to cyclophosphamide (CYC) for remission induction…
  • Abstract Number: 1544 • ACR/ARHP Annual Meeting 2012

    Long-Term Outcome of Patients with Granulomatosis with Polyangiitis (Wegener’s) Treated with Rituximab

    Lama Azar1, Jason Springer2, Meng Xu3, Tiffany M. Clark4, Carol A. Langford5 and Gary S. Hoffman4, 1Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, Cleveland, OH, 2Dept of Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 3Section of biostatistics, Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 4Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, 5Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Rituximab (RTX) is an efficacious alternative to cyclophosphamide for treatment of granulomatosis with polyangiitis (GPA). However, relapses have been observed, long-term efficacy is not…
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