Abstracts tagged "Vitamin D"

Abstract Number: 2653 • 2013 ACR/ARHP Annual Meeting
Low Vitamin D Is Associated With Increased Risk of Venous Thrombosis in Systemic Lupus Erythematosus, Regardless of Lupus Anticoagulant Status
Michelle Petri and Hong Fang, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Vitamin D deficiency is common in SLE. Vitamin D deficiency is also associated with activation of Tissue Factor. In cross-sectional studies, vitamin D deficiency…
Abstract Number: 1690 • 2013 ACR/ARHP Annual Meeting
Impaired Vitamin D Receptor Signaling Upregulates Transforming Growth Factor Beta (TGFβ) Signaling In Systemic Sclerosis
Pawel Zerr¹, Stefan Vollath¹, Katrin Palumbo-Zerr¹, Michal Tomcik², Jingang Huang¹, Alfiya Distler¹, Christian Beyer¹, Clara Dees¹, Oliver Distler³, Georg Schett⁴ and Joerg H. W. Distler¹, ¹Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Vitamin D receptor (VDR) is a member of the nuclear receptor superfamily. Its ligand, 1,25-(OH)2D, is a metabolically active hormone derived from vitamin D3.…
Abstract Number: 1530 • 2013 ACR/ARHP Annual Meeting
Vitamin D Deficiency Is Associated With a More Active and Severe Disease In Early Axial Spondyloarthritis: Data From The DESIR Cohort
Ihsane Hmamouchi¹, Simon Paternotte², Didier Borderie³ and Maxime Dougados⁴, ¹Biostatistics, Epidemiology LBRCE, Mohamed V Souissi University, Rabat, Morocco, ²Rheumatology Department, Paris- Descartes University, Cochin hospital, Paris, France, ³Laboratoire de Biochimie, Hopital Cochin, Paris Descartes University, Pris, France, ⁴Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France
Background/Purpose: Objectives a) to describe the vitamin D status b) to assess the relationship between vitamin D status and disease activity/severity and c) to estimate…
Abstract Number: 1274 • 2013 ACR/ARHP Annual Meeting
Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus
Amit Saxena¹, Peter M. Izmirly², Joanne H. Reed³, Sara Sahl², Deborah Friedman⁴, Robert M. Clancy³ and Jill P. Buyon², ¹Rheumatology, New York University School of Medicine, New York, NY, ²Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Medicine, New York University School of Medicine, New York, NY, ⁴Division of Pediatric Cardiology, New York Medical College, Valhalla, NY
Background/Purpose: Women with anti-Ro antibodies face the risk of having a child with cardiac Neonatal Lupus (NL), characterized by congenital heart block and/or cardiomyopathy. Biomarkers…
Abstract Number: 1241 • 2013 ACR/ARHP Annual Meeting
A Low Serum 25(OH) Vitamin D Level As a Risk Factor For Incidence and Severity Of Vertebral Fracture In Glucocorticoid-Induced Osteoporosis In Japan
Mari Ushikubo¹, Harumi Kuda¹, Sayaka Kubo¹, Keisuke Izumi², Kumiko Akiya¹ and Hisaji Oshima¹, ¹Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ²Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Although levels of serum 25(OH) vitamin D (25(OH)D) have been discussed for preventing osteoporotic fractures in primary osteoporosis, an importance of the levels has…
Abstract Number: 1217 • 2013 ACR/ARHP Annual Meeting
Determination Of Vitamin D Level Prior To The Initiation Of Bisphosphonate Therapy
Chris T. Derk¹, Ruchika Patel², Rennie L. Rhee², Yiu Tak Leung¹, R. Michelle Koolaee², Shiv Sehra² and Ashwini Komarla³, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Rheumatology, University of Pennsylvania, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Vitamin D deficiency is under-recognized and in 18-35% of patients who do not respond to bisphosphonates, concurrent use of vitamin D 1000 units daily…
Abstract Number: 1096 • 2013 ACR/ARHP Annual Meeting
Is Vitamin D Deficiency a Risk Factor For The Development Of Statin Induced Myalgia, In Patients Treated With Statin?
Ozlem Tasoglu¹, Yesim Kutsal¹, Irfan Tasoglu², Oya Ozdemir³ and Yildiz Erdoganoglu⁴, ¹Physical Medicine and Rehabilitation, Hacettepe University Faculty of Medicine, Ankara, Turkey, ²Cardiovascular Surgery, Türkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey, ³Department of Physical Medicine and Rehabilitation, Hacettepe University Faculty of Medicine, Ankara, Turkey, ⁴Physiotherapy, Hacettepe University, Ankara, Turkey
Background/Purpose: Vitamin D deficiency has become pandemic in the industrializing societies. Recently, the role of vitamin D deficiency in the development of statin myopathy has…
Abstract Number: 711 • 2013 ACR/ARHP Annual Meeting
1,25(OH)₂D₃ Inhibits Th17 Cytokine Production and RORγt Expression Through GATA3/IL4-Dependent and -Independent Mechanisms
Wendy Dankers¹, Jan Piet van Hamburg^2,3, Anne-Marie Mus¹, Patrick S. Asmawidjaja¹, Johannes van Leeuwen⁴, Rudi W. Hendriks⁵, Louis Boon⁶, Edgar Colin⁷ and Erik Lubberts^1,8, ¹Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ²Rheumatology, Erasmus MC, Rotterdam, Netherlands, ³Immunology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁴Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁵Pulmonary Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁶Bioceros, Utrecht, Netherlands, ⁷Department of Rheumatology, ZGT, Almelo, Netherlands, ⁸Erasmus Medical Center, Rheumatology, Rotterdam, Netherlands
Background/Purpose: Vitamin D has suppressive effects on autoimmune diseases, such as rheumatoid arthritis (RA). One important mechanism of disease suppression by vitamin D is inhibition…
Abstract Number: 641 • 2013 ACR/ARHP Annual Meeting
Vitamin D Increases The Number and Function Of Myeloid Angiogenic Cells In Systemic Lupus Erythematosus
John A. Reynolds¹, David W. Ray², Terence O'Neill³, M. Yvonne Alexander⁴ and Ian N. Bruce⁵, ¹Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, United Kingdom, Manchester, United Kingdom, ²Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ⁴Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, ⁵Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Patients with Systemic Lupus Erythematosus (SLE) have an increased prevalence of cardiovascular disease (CVD). Vitamin D deficiency is common in SLE and an independent…
Abstract Number: 388 • 2013 ACR/ARHP Annual Meeting
Vitamin D Levels and Inflammation In The Aortic Wall Of Patients With Inflammatory Rheumatic Disease and Coronary Artery Disease
Ingvild Oma¹, Jacqueline Kirsti Andersen², Torstein Lyberg³, Øyvind Molberg⁴, Jon Elling Whist¹, Ingjerd Lien Kvelstad¹, Terje Veel⁵, Morten Fagerland⁶, Sven M. Almdahl⁷, Knut Mikkelsen⁸ and Ivana Hollan⁹, ¹Innlandet Hospital Trust, Lillehammer, Norway, ²Gjøvik University College, Gjøvik, Norway, ³Oslo University Hospital, Oslo, Norway, ⁴Institute of Clinical Medicine, University of Oslo, Oslo, Norway, ⁵Feiringklinikken, Feiring, Norway, ⁶Department of Biostatistics, Oslo University Hospital, Oslo, Norway, ⁷Cardiothoracic surgery, University Hospital of North Norway, Tromsø, Norway, ⁸Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁹Rheumatology, Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway
Background/Purpose: Vitamin D is involved in immune reactions, and vitamin D deficiency is associated with autoimmune diseases and with cardiovascular diseases. In Feiring Heart Biopsy…
Abstract Number: 394 • 2013 ACR/ARHP Annual Meeting
Vitamin D Deficiency In Patients With Early Inflammatory Arthritis
Seung-Geun Lee¹, Guen-Tae Kim², Joung-Wook Lee³, Seong-Ho Kim⁴ and Seung-Hoon Baek⁵, ¹Divsion of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Kosin University College of Medicine, Busan, South Korea, ³Divsion of Rheumatology, Department of Internal Medicine, Busan St. Mary’s Medical Center, Busan, South Korea, ⁴Division of Rheumatology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea, ⁵Divsion of Rheumatology, Department of Internal Medicine, Ilsin Christian Hospital, Busan, South Korea
Background/Purpose: To investigate the status of vitamin D in patients with early inflammatory arthritis (EIA) compared with healthy controls.Methods: The study included 101 patients with…
Abstract Number: 89 • 2013 ACR/ARHP Annual Meeting
Meta-Analysis of Randomized Controlled Trials Assessing the Effects of Vitamin D Supplementation On Skeletal Muscle Strength
Charlotte Beaudart¹, Fanny Buckinx², Véronique Rabenda³, Sophie Gillain⁴, Etienne Cavalier⁵, Jean Petermans⁴, Jean-Yves Reginster⁶ and Olivier Bruyere¹, ¹Public Health/Epidemiology, University of Liege, Liege, Belgium, ²Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, ³Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium, ⁴Geriatric Department, CHU de Liege, Liege, Belgium, ⁵Department of Clinical Chemistry, CHU de Liege, Liege, Belgium, ⁶Department of Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium
Background/Purpose: Currently, there is growing evidence that vitamin D plays a role on several tissues including skeletal muscle. Previous studies suggested that vitamin D deficiency is…

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