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Abstracts tagged "Vitamin D"

  • Abstract Number: 641 • 2013 ACR/ARHP Annual Meeting

    Vitamin D Increases The Number and Function Of Myeloid Angiogenic Cells In Systemic Lupus Erythematosus

    John A. Reynolds1, David W. Ray2, Terence O'Neill3, M. Yvonne Alexander4 and Ian N. Bruce5, 1Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, United Kingdom, Manchester, United Kingdom, 2Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom, 3Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, 4Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, 5Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: Patients with Systemic Lupus Erythematosus (SLE) have an increased prevalence of cardiovascular disease (CVD).  Vitamin D deficiency is common in SLE and an independent…
  • Abstract Number: 388 • 2013 ACR/ARHP Annual Meeting

    Vitamin D Levels and Inflammation In The Aortic Wall Of Patients With Inflammatory Rheumatic Disease and Coronary Artery Disease

    Ingvild Oma1, Jacqueline Kirsti Andersen2, Torstein Lyberg3, Øyvind Molberg4, Jon Elling Whist1, Ingjerd Lien Kvelstad1, Terje Veel5, Morten Fagerland6, Sven M. Almdahl7, Knut Mikkelsen8 and Ivana Hollan9, 1Innlandet Hospital Trust, Lillehammer, Norway, 2Gjøvik University College, Gjøvik, Norway, 3Oslo University Hospital, Oslo, Norway, 4Institute of Clinical Medicine, University of Oslo, Oslo, Norway, 5Feiringklinikken, Feiring, Norway, 6Department of Biostatistics, Oslo University Hospital, Oslo, Norway, 7Cardiothoracic surgery, University Hospital of North Norway, Tromsø, Norway, 8Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, 9Rheumatology, Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway

    Background/Purpose: Vitamin D is involved in immune reactions, and vitamin D deficiency is associated with autoimmune diseases and with cardiovascular diseases. In Feiring Heart Biopsy…
  • Abstract Number: 394 • 2013 ACR/ARHP Annual Meeting

    Vitamin D Deficiency In Patients With Early Inflammatory Arthritis

    Seung-Geun Lee1, Guen-Tae Kim2, Joung-Wook Lee3, Seong-Ho Kim4 and Seung-Hoon Baek5, 1Divsion of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Kosin University College of Medicine, Busan, South Korea, 3Divsion of Rheumatology, Department of Internal Medicine, Busan St. Mary’s Medical Center, Busan, South Korea, 4Division of Rheumatology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea, 5Divsion of Rheumatology, Department of Internal Medicine, Ilsin Christian Hospital, Busan, South Korea

    Background/Purpose: To investigate the status of vitamin D in patients with early inflammatory arthritis (EIA) compared with healthy controls.Methods: The study included 101 patients with…
  • Abstract Number: 89 • 2013 ACR/ARHP Annual Meeting

    Meta-Analysis of Randomized Controlled Trials Assessing the Effects of Vitamin D Supplementation On Skeletal Muscle Strength

    Charlotte Beaudart1, Fanny Buckinx2, Véronique Rabenda3, Sophie Gillain4, Etienne Cavalier5, Jean Petermans4, Jean-Yves Reginster6 and Olivier Bruyere1, 1Public Health/Epidemiology, University of Liege, Liege, Belgium, 2Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, 3Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium, 4Geriatric Department, CHU de Liege, Liege, Belgium, 5Department of Clinical Chemistry, CHU de Liege, Liege, Belgium, 6Department of Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium

    Background/Purpose: Currently, there is growing evidence that vitamin D plays a role on several tissues including skeletal muscle. Previous studies suggested that vitamin D deficiency is…
  • Abstract Number: 2674 • 2013 ACR/ARHP Annual Meeting

    Vitamin D Deficiency Is Common and Associated With Increased C-Reactive Protein In Children With Lupus: An Atherosclerosis Prevention In Pediatric Lupus Erythematosus Substudy

    Angela B. Robinson1, Vin Tangpricha2, Eric Yow3, Reut Gurion4, Grace McComsey4 and Laura E. Schanberg5, 1Pediatric Infectious Disease, Rheumatology and Geographic Medicine, Rainbow Babies and Children's Hospital / Case Medical Center, Cleveland, OH, 2Medicine, Emory University School of Medicine, Atlanta, GA, 3Biostatistics, Duke Clinical Research Institute, Durham, NC, 4Pediatric Infectious Diseases, Rheumatology, and Geographic Medicine, Rainbow Babies and Children's Hospital / Case Medical Center, Cleveland, OH, 5Pediatrics, Duke University Medical Center, Durham, NC

    Background/Purpose: Epidemiologic associations suggest vitamin D may play a role in inflammation and progression of atherosclerosis. Using frozen serum, carotid intima medial thickness (CIMT) measurements,…
  • Abstract Number: 2653 • 2013 ACR/ARHP Annual Meeting

    Low Vitamin D Is Associated With Increased Risk of Venous Thrombosis in Systemic Lupus Erythematosus, Regardless of Lupus Anticoagulant Status

    Michelle Petri and Hong Fang, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Vitamin D deficiency is common in SLE. Vitamin D deficiency is also associated with activation of Tissue Factor. In cross-sectional studies, vitamin D deficiency…
  • Abstract Number: 1690 • 2013 ACR/ARHP Annual Meeting

    Impaired Vitamin D Receptor Signaling Upregulates Transforming Growth Factor Beta (TGFβ) Signaling In Systemic Sclerosis

    Pawel Zerr1, Stefan Vollath1, Katrin Palumbo-Zerr1, Michal Tomcik2, Jingang Huang1, Alfiya Distler1, Christian Beyer1, Clara Dees1, Oliver Distler3, Georg Schett4 and Joerg H. W. Distler1, 1Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 2Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 3Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 4Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose: Vitamin D receptor (VDR) is a member of the nuclear receptor superfamily. Its ligand, 1,25-(OH)2D, is a metabolically active hormone derived from vitamin D3.…
  • Abstract Number: 1530 • 2013 ACR/ARHP Annual Meeting

    Vitamin D Deficiency Is Associated With a More Active and Severe Disease In Early Axial Spondyloarthritis: Data From The DESIR Cohort

    Ihsane Hmamouchi1, Simon Paternotte2, Didier Borderie3 and Maxime Dougados4, 1Biostatistics, Epidemiology LBRCE, Mohamed V Souissi University, Rabat, Morocco, 2Rheumatology Department, Paris- Descartes University, Cochin hospital, Paris, France, 3Laboratoire de Biochimie, Hopital Cochin, Paris Descartes University, Pris, France, 4Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France

    Background/Purpose: Objectives a) to describe the vitamin D status b) to assess the relationship between vitamin D status and disease activity/severity and c) to estimate…
  • Abstract Number: 1274 • 2013 ACR/ARHP Annual Meeting

    Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus

    Amit Saxena1, Peter M. Izmirly2, Joanne H. Reed3, Sara Sahl2, Deborah Friedman4, Robert M. Clancy3 and Jill P. Buyon2, 1Rheumatology, New York University School of Medicine, New York, NY, 2Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3Medicine, New York University School of Medicine, New York, NY, 4Division of Pediatric Cardiology, New York Medical College, Valhalla, NY

    Background/Purpose: Women with anti-Ro antibodies face the risk of having a child with cardiac Neonatal Lupus (NL), characterized by congenital heart block and/or cardiomyopathy.  Biomarkers…
  • Abstract Number: 1241 • 2013 ACR/ARHP Annual Meeting

    A Low Serum 25(OH) Vitamin D Level As a Risk Factor For Incidence and Severity Of Vertebral Fracture In Glucocorticoid-Induced Osteoporosis In Japan

    Mari Ushikubo1, Harumi Kuda1, Sayaka Kubo1, Keisuke Izumi2, Kumiko Akiya1 and Hisaji Oshima1, 1Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, 2Division of Rheumatology, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: Although levels of serum 25(OH) vitamin D (25(OH)D) have been discussed for preventing osteoporotic fractures in primary osteoporosis, an importance of the levels has…
  • Abstract Number: 1217 • 2013 ACR/ARHP Annual Meeting

    Determination Of Vitamin D Level Prior To The Initiation Of Bisphosphonate Therapy

    Chris T. Derk1, Ruchika Patel2, Rennie L. Rhee2, Yiu Tak Leung1, R. Michelle Koolaee2, Shiv Sehra2 and Ashwini Komarla3, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Rheumatology, University of Pennsylvania, Philadelphia, PA, 3University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Vitamin D deficiency is under-recognized and in 18-35% of patients who do not respond to bisphosphonates, concurrent use of vitamin D 1000 units daily…
  • Abstract Number: 1096 • 2013 ACR/ARHP Annual Meeting

    Is Vitamin D Deficiency a Risk Factor For The Development Of Statin Induced Myalgia, In Patients Treated With Statin?

    Ozlem Tasoglu1, Yesim Kutsal1, Irfan Tasoglu2, Oya Ozdemir3 and Yildiz Erdoganoglu4, 1Physical Medicine and Rehabilitation, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Cardiovascular Surgery, Türkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey, 3Department of Physical Medicine and Rehabilitation, Hacettepe University Faculty of Medicine, Ankara, Turkey, 4Physiotherapy, Hacettepe University, Ankara, Turkey

    Background/Purpose: Vitamin D deficiency has become pandemic in the industrializing societies. Recently, the role of vitamin D deficiency in the development of statin myopathy has…
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