Abstracts tagged "Vasculitis"

Abstract Number: 2493 • ACR Convergence 2024
Mortality in Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis: Study from a Single University Hospital
Fabricio Benavides¹, Alba Herrero-Morant², Diana Prieto-Peña³, Vanesa Calvo-Rio⁴, Salma Al Fazazi⁵, Adrián Martín-Gutiérrez⁶, Mónica Renuncio-García⁷, Amparo Sánchez-López⁸, Claudia Poo-fernandez⁸, Clara Escagedo-Cagigas⁸, Maria Rodríguez-Vidriales¹ and Ricardo Blanco-Alonso⁹, ¹Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, ²Hospital Universitario Marqués de Valdecilla, Ontinyent, Cantabria, Spain, ³Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, ⁴Valdecilla Hospital, Santander, Cantabria, Spain, ⁵Hospital Universitario Virgen de la Victoria, Málaga, Andalucia, Spain, ⁶Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, ⁷Division of Immunology, Hospital Universitario Marqués de Valdecilla, Immunopathology Group, IDIVAL, Santander, Spain, ⁸Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁹Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis (AAV) includes Granulomatosis with polyangiitis (GPA), Microscopic polyarteritis (MPA) and Eosinophilic granulomatosis with polyangiitis (EGPA). Due to clinical,…
Abstract Number: 2518 • ACR Convergence 2024
Behçet’s Disease Immune Landscape Exhibits a Universal NF-kB-mediated Hyperactivation Pattern with Cell-specific TNFAIP3 Responses and a Superimposed IFN-regulated Endotype
Yesim Ozguler¹, Olivier Manches², Didar Ucar³, Ziyan Lin², Alireza Khodadadi-Jamayran², Aristotelis Tsirigos², Gulen Hatemi¹ and Johannes Nowatzky⁴, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²NYU Grossman School of Medicine, New York, NY, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Ophthalmology, Istanbul, Turkey, ⁴New York University Grossman School of Medicine, New York, NY
Background/Purpose: The immune landscape of Behçet’s disease (BD) remains ill-defined, lacking a unifying picture, precise disease phenotype-endotype correlations, and an understanding of immunity at target…
Abstract Number: 0715 • ACR Convergence 2024
Diffuse Alveolar Hemorrhage in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Revisited
Samuel Falde¹, Elif Ediboglu¹, Misbah Baqir¹, Rodrigo Cartin-Ceba², Fernando C. Fervenza¹, Ladan Zand¹, Matthew Koster¹, Kenneth Warrington¹ and Ulrich Specks¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Scottsdale, AZ
Background/Purpose: We sought to characterize the most recent cohort of patients presenting with DAH and AAV and to identify risk factors for respiratory failure and…
Abstract Number: 0753 • ACR Convergence 2024
Treatment and Evolution in 134 Patients with Aortitis and Periaortitis. Experience of a Single Referral Centre
Carmen Secada Gómez¹, Javier Loricera², Adrián Martín-Gutiérrez³, Fernando Lopez-Gutierrez⁴, Santos Castañeda⁵ and Ricardo Blanco-Alonso⁶, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, ⁵Hospital Universitario de la Princesa, Madrid, Spain, ⁶Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Aortitis and periaortitis include a heterogeneous group of entities that may be idiopathic or secondary to infectious and non-infectious processes. Therefore, treatment will differ…
Abstract Number: 0849 • ACR Convergence 2024
Effectiveness of Tocilizumab in Aortitis and Aneurysms Associated with Giant Cell Arteritis. Multicenter Open-label Study
Adrián Martín-Gutiérrez¹, Javier Loricera², Carmen Secada Gómez³, Iñigo Hernández-Rodríguez⁴, Susana Romero Yuste⁵, Eugenio De Miguel⁶, Eva Galindez-Agirregoikoa⁷, ivan Ferraz-Amaro⁸, Julio Sánchez-Martín⁹, Patricia Moya Albarado¹⁰, Cristina Campos Fernández¹¹, Fernando Lopez-Gutierrez¹², Santos Castañeda¹³ and Ricardo Blanco-Alonso¹⁴, and the Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group, ¹Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ⁴Complejo Hospitalario Universitario de Vigo, Vigo, Spain, ⁵Department of Rheumatology, University Hospital Complex of Pontevedra, Pontevedra, Spain, ⁶Hospital Universitario La Paz, Madrid, Spain, ⁷BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, ⁸Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, ⁹Hospital Universitario 12 de Octubre, Madrid, Spain, ¹⁰Hospital de San Pau, Barcelona, Spain, ¹¹Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, ¹²Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, ¹³Hospital Universitario de la Princesa, Madrid, Spain, ¹⁴Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Giant Cell Arteritis (GCA) was initially described involving mainly the extracranial branches of the carotid arteries. However, GCA also may involve the aorta (GCA-aortitis)…
Abstract Number: 1615 • ACR Convergence 2024
Is Regular Vascular Imaging Scheduled Essential in the Follow-Up of Takayasu Arteritis? A Large-Scale Multicenter Cohort Study
Fatih Yildirim¹, Cemal Bes², Muhammet Emin Kutu³, Fatih Tastekin⁴, Gokhan Keser⁵, Tugba Ocak⁶, Ediz Dalkilic⁶, Yavuz Pehlivan⁶, Hasan Kocaayan⁷, Servet Akar⁷, Sema İsik⁸, Ahmet Omma⁹, Senar San¹⁰, Ayten Yazici¹¹, Ayse Cefle¹¹, Safiye Bakkal¹², Gökçe Kenar¹³, Fatos Onen¹², Aysegül Avcu¹⁴, Fatma Alibaz Öner¹⁵, Haner Direskeneli¹⁵, Burcu Ceren Uludogan¹⁶, Nazife Sule yaşar Bile¹⁶ and Nilüfer Alpay Kanıtez¹⁷, ¹University of Health Sciences Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey, İstanbul, Turkey, ²University of Health Sciences Başakşehir Çam and Sakura City HospitalUniversity of Health Sciences Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey, İstanbul, Turkey, ³Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey, ⁴Ege University School of Medicine, Rheumatology, İzmir, Turkey, İzmir, Turkey, ⁵Ege University School of Medicine, Rheumatology, İzmir, Turkey, Izmir, Turkey, ⁶Uludağ University Faculty of Medicine, Rheumatology, Bursa, Turkey, Bursa, Turkey, ⁷İzmir Katip Celebi University School of Medicine, Rheumatology, İzmir, Turkey, İzmir, Turkey, ⁸University of Health Sciences Ankara Bilkent City Hospital, Rheumatology, Ankara, Turkey, Ankara, Turkey, ⁹Ankara Bilkent City Hospital, Ankara, Turkey, ¹⁰Kocaeli University Faculty of Medicine, Rheumatology, Kocaeli, Turkey, Kocaeli, Turkey, ¹¹Kocaeli University Faculty of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ¹²Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, İzmir, Turkey, ¹³Dokuz Eylul University School of Medicine, Izmir, Turkey, ¹⁴Marmara University Faculty of Medicine, Rheumatology, İstanbul, Turkey, İstanbul, Turkey, ¹⁵Marmara University Faculty of Medicine, Rheumatology, İstanbul, Turkey, Istanbul, Turkey, ¹⁶Osmangazi University Faculty of Medicine, Rheumatology, Eskişehir, Turkey, Eskisehir, Turkey, ¹⁷Koc University Faculty of Medicine, Rheumatology, İstanbul, Turkey, Istanbul, Turkey
Background/Purpose: The understanding of progression or minimal disease activity in patients with Takayasu arteritis (TA) can be complicated due to the possibility of mild vascular…
Abstract Number: 1641 • ACR Convergence 2024
Orbital MRI as a Promising Approach for the Diagnosis of Giant Cell Arteritis in Case of Anterior Ischemic Optical Neuropathy or Central Retinal Artery Occlusion
Guillaume BRENAC¹, Angélique BERNARD¹, Hélène GREIGERT¹, Brivael LEMOGNE², Andre Ramon³, Sylvain AUDIA¹, Vanessa LEGUY-SEGUIN¹, Jérôme RAZANAMAHERY¹, Louis ARNOULD¹, Catherine CREUZOT-GARCHER¹, Bernard Bonnotte⁴ and Maxime SAMSON¹, ¹Dijon University Hospital, Dijon, France, ²Dijon University Hopital, Dijon, France, ³Dijon University Hospital, Besançon, France, ⁴Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France., Dijon, France
Background/Purpose: Vision loss associated with acute anterior ischemic optic neuropathy (AION) or central retinal artery occlusion (CRAO) can reveal giant cell arteritis (GCA). In this…
Abstract Number: 2495 • ACR Convergence 2024
Diffuse Alveolar Hemorrhage in Patient with ANCA-associated Vasculitis AndInterstitial Lung Disease
Elif Ediboglu¹, Samuel Falde¹, Misbah Baqir¹, Rodrigo Cartin-Ceba² and Ulrich Specks¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Scottsdale, AZ
Background/Purpose: The association of interstitial lung disease (ILD) and microscopic polyangiitis (MPA) is increasingly recognized. The implications of ILD as it relates to clinical outcomes…
Abstract Number: 2519 • ACR Convergence 2024
What Do We Know About Malignancies in IgA Vasculitis?
Alojzija Hocevar¹, Jaka Ostrovrsnik², vesna Jurcic³ and Ziga Rotar⁴, ¹University Medical Center Ljubljana, LJUBLJANA, Slovenia, ²UMC Ljubljana, Dpt. of Rheumatology, Ljubljana, Slovenia, ³Medical Faculty, University of Ljubljana, Institute of pathology, Ljubljana, Slovenia, ⁴University Medical Centre Ljubljana and University of Ljubljana, Ljubljana, Slovenia
Background/Purpose: Cancer has been reported as a potential trigger of IgA vasculitis (IgAV) in adults, however data on this topic is scarce. The aim of…
Abstract Number: 0717 • ACR Convergence 2024
Associations Between Calendar Time and Age at Diagnosis with Mortality in a National Cohort of Veterans with ANCA-Associated Vasculitis from 2001-2020
Jennifer Hanberg¹, Svetlana Eden², Amy Anderson-Mellies², Suman Kundu², Matthew Freiberg², Zachary Wallace³ and Evelyn Hsieh⁴, and the Veterans Aging Cohort Study Project Team, ¹Brigham and Women's Hospital, Boston, MA, ²Vanderbilt University Medical Center and Tennessee Valley VA, Nashville, TN, ³Massachusetts General Hospital, Newton, MA, ⁴Yale School of Medicine / VA Connecticut Healthcare System, West Haven, Connecticut, New Haven, CT
Background/Purpose: It is not clear whether advances in ANCA-associated vasculitis (AAV) management between 2001-2020 have translated to improvement in population-level outcomes, including among older adults.…
Abstract Number: 0754 • ACR Convergence 2024
Clinical Characterization of Aortitis and Periaortitis in a Cohort of 134 Patients from a Single Universitary Center. A Model-based Cluster Analysis
Carmen Secada Gómez¹, Javier Loricera², Adrián Martín-Gutiérrez³, Fernando Lopez-Gutierrez⁴, María Nuñez-Sayar⁵, Ander Ucelay-Aristi⁵, Isabel Martinez-Rodriguez⁶, ivan Ferraz-Amaro⁷, Santos Castañeda⁸ and Ricardo Blanco-Alonso⁹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, ⁵Cardiovascular Surgery, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, ⁶Nuclear Medicine, Hospital Universitario Marques de Valdecilla,IDIVAL, Santander, Cantabria, Spain, ⁷Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, ⁸Hospital Universitario de la Princesa, Madrid, Spain, ⁹Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain
Background/Purpose: Aortitis and periaortitis represent the inflammation of the aortic wall and the surrounding periaortic tissues, respectively. Both can be idiopathic or secondary to infectious…
Abstract Number: 0854 • ACR Convergence 2024
The OMERACT GCA Phantom Project: Validation of 3D Printed Ultrasound Training Models for Giant Cell Arteritis
Valentin Sebastian Schäfer¹, Tobias Schremmer², Florian Recker³, Wolfgang Hartung⁴, Christina Duftner⁵, Sara Monti⁶, Alojzija Hocevar⁷, Rositsa Karalilova⁸, Annamaria Iagnocco⁹, pierluigi macchioni¹⁰, Giuseppe Antonio Germano¹¹, ESPERANZA NAREDO¹², Eugenio De Miguel¹³, Luca Seitz¹⁴, Thomas Daikeler¹⁵, Dennis Boumans¹⁶, Chetan Mukhtyar¹⁷, Kate Smith¹⁸, Richard Wakefield¹⁸, Andreas Diamantopoulos¹⁹, Stavros Chrysidis²⁰, Berit Dalsgaard Nielsen²¹, Kresten Keller²², Uffe Moller Dohn²³, Lene Terslev²⁴, Marcin Milchert²⁵, Wolfgang Schmidt²⁶, George A. W. Bruyn²⁷, Aaron Juche²⁸ and Christian Dejaco²⁹, ¹Clinic of Internal Medicine III, Department of Rheumatology, University Hospital of Bonn, Bonn, Germany, 53127 Bonn, Nordrhein-Westfalen, Germany, ²Helios Klinikum Bonn/Rhein-Sieg, Bonn, Germany, ³Department for Gynecology and Obstetrics, University Hospital Bonn, Germany, Bonn, Germany, ⁴Asklepios Clinic, Tegernheim, Germany, ⁵Medical University Innsbruck/Tirol Kliniken GmbH, Innsbruck, Austria, ⁶IRCCS Istituto Auxologico Italiano, Milan, Italy, ⁷University Medical Center Ljubljana, LJUBLJANA, Slovenia, ⁸Medical University of Plovdiv, Bulgaria, Plovdiv, Bulgaria, ⁹University of Turin, Italy, Roma, Italy, ¹⁰SERVIZIO REUMATOLOGIA IRCCS REGGIO EMILIA, Reggio Emilia, Italy, ¹¹Rheumatology Unit- Arcispedale Santa Maria Nuova Reggio Emilia-Italy, Reggio Emilia, Italy, ¹²Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ¹³Hospital Universitario La Paz, Madrid, Spain, ¹⁴Inselspital, Liebefeld, Switzerland, ¹⁵university hospital, Basel, Switzerland, ¹⁶Ziekenhuisgroep Twente (Hospital Group Twente), Borne, Netherlands, ¹⁷Norfolk and Norwich University Hospital, Norwich, United Kingdom, ¹⁸NIHR Leeds Biomedical Research Centre, Leeds, UK., Leeds, United Kingdom, ¹⁹Akershus University Hospital, Lørenskog, Norway, ²⁰Department of Rheumatology, University Hospital of Southern Denmark, Esbjerg, Denmark, ²¹Department of Rheumatology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, Vejle, Denmark, ²²Aarhus University Hospital, Aarhus, Denmark, ²³Rigshospitalet-Glostrup, Glostrup, Denmark, ²⁴Rigshospitalet-Glostrup & COPECARE, Glostrup, Denmark, ²⁵Department of Rheumatology, Internal Medicine, Geriatrics and Clinical Immunology, Pomeranian Medical University, Szczecin, Poland., Szczecin, Poland, ²⁶Immanuel Krankenhaus Berlin, Berlin, Germany, ²⁷Reumakliniek Lelystad, Loenga, Netherlands, ²⁸Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, Berlin, Germany, ²⁹Azienda Sanitaria Alto Adige, Brunico, Italy
Background/Purpose: Ultrasonography has been validated as a diagnostic tool for giant cell arteritis (GCA). Due to the urgent need for glucocorticoid treatment in acute GCA…
Abstract Number: 1616 • ACR Convergence 2024
Vitamin D Supplementation in the Prevention of Severe Adverse Effects Caused ByGlucocorticoids: Study from the ARTESER Registry of Giant Cell Arteritis
Gaston Ariel Ghio¹, Marta Domínguez-Álvaro², Ricardo Blanco-Alonso³, Santos Castañeda⁴, Iñigo Hernández-Rodríguez⁵, Elisa Fernández-Fernández:⁶, Maite Silva-Diaz⁷, Joaquin María Belzunegui:⁸, Clara Moriano⁹, Julio Sánchez-Martín¹⁰, Javier Narvaez-García¹¹, Eva Galindez¹², Anne Riveros Frutos¹³, Francisco Ortiz Sanjuán¹⁴, Tarek Carlos Salman Monte:¹⁵, Margarida Vasques Rocha:¹⁶, Carlota L Iñiguez:¹⁷, Alicia García Dorta¹⁸, Clara Molina Almela¹⁹ and María Alcalde Villar:²⁰, and ARTESER Project Collaborative Group, ¹Hospital Universitari Mutua Terrassa, Terrassa, Catalonia, Spain, ²Sociedad Española de Reumatología, Madrid, Spain, ³Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain, ⁴Hospital Universitario de la Princesa, Madrid, Spain, ⁵Complejo Hospitalario Universitario de Vigo, Vigo, Spain, ⁶La Paz University Hospital, Alcalá de Henares, Madrid, Spain, ⁷Complejo Hospitalario Universitario A Coruña, A Coruña, Spain, ⁸H de Donostia, Donostia-San Sebasti, Spain, ⁹Hospital León, LEON, Spain, ¹⁰Hospital Universitario 12 de Octubre, Madrid, Spain, ¹¹Hospital Universitario de Bellvitge, Barcelona, Spain, ¹²Hospital Universitario de Cabueñes, Bilbao, Spain, ¹³Hospital Universitari Germans Trias i Pujol, Barcelona, Spain, ¹⁴Hospital Universitario de Cabueñes, Gijón, Asturias, Spain, ¹⁵Hospital del Mar/Parc de Salut Mar-IMIM, Barcelona, Spain, ¹⁶Hospital Universitario Araba, Vitoria, Spain, ¹⁷Hospital Universitario Lucus Augusti, Galicia, Spain, Galicia, Spain, ¹⁸Rheumatologist, La Laguna, Spain, ¹⁹Consorcio Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, ²⁰Hospital Universitario Severo Ochoa Leganés, Madrid, Spain, Madrid, Spain
Background/Purpose: Glucocorticoids (GC) are the gold standard for the treatment of giant cellarteritis (GCA). However, these drugs, when used at high doses and for prolonged…
Abstract Number: 1695 • ACR Convergence 2024
Efficacy of Upadacitinib in Patients with Giant Cell Arteritis: Subgroup Analysis of the SELECT-GCA Phase 3 Trial
Peter Merkel¹, Arathi Setty², Ricardo Blanco-Alonso³, Ravi Suppiah⁴, Thomas Daikeler⁵, Valerie Devauchelle⁶, Elisabeth Brouwer⁷, Hiromichi Tamaki⁸, Liu Meng², Yang Yang², Avani Joshi², Charles Phillips², Peter K. Wung² and Cristina Ponte⁹, ¹Division of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, ²AbbVie, North Chicago, IL, ³Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain, ⁴Health New Zealand, Te Toka Tumai Auckland, Auckland, New Zealand, ⁵university hospital, Basel, Switzerland, ⁶UBO, Brest, France, ⁷University Medical Center Groningen, Groningen, Netherlands, ⁸St. Luke's International Hospital, Tokyo, Japan, ⁹Unidade Local de Saúde Santa Maria, Serviço de Reumatologia e Doenças Ósseas Metabólicas, Lisboa, Portugal., Lisbon, Portugal
Background/Purpose: Giant cell arteritis (GCA) is a chronic systemic vasculitis with limited targeted therapeutic options. The recent SELECT-GCA phase 3 trial demonstrated a favorable benefit-risk…
Abstract Number: 2496 • ACR Convergence 2024
Clinical Features and Outcomes of Hydralazine-associated Vasculitis: A Case-Control Study
Elif Ediboglu¹, Samuel Falde¹, Misbah Baqir¹, Rodrigo Cartin-Ceba² and Ulrich Specks¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Scottsdale, AZ
Background/Purpose: We aimed to investigate the relationship between hydralazine and any form of vasculitis (small, medium, or large vessel), to describe clinical features and outcomes…

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