Abstract Number: 1680 • 2019 ACR/ARP Annual Meeting
Design of a Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of 2 Different Dose Regimens of IFX-1, a C5a Inhibitor, as an Add-On Therapy for Granulomatosis with Polyangiitis or Microscopic Polyangiitis
Background/Purpose: Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are life-threatening rare autoimmune diseases to anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Standard of care (SOC)…Abstract Number: 2630 • 2019 ACR/ARP Annual Meeting
A Dutch Consensus Statement on the Diagnosis and Treatment of ANCA Associated Vasculitis
Background/Purpose: Several guidelines have been published on the diagnosis and treatment of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis (AAV). These guidelines provide an evidence-based approach…Abstract Number: 810 • 2019 ACR/ARP Annual Meeting
Small Vessel Vasculitis Syndrome with Autoinflammation Caused by De Novo Mutations in LYN Kinase
Background/Purpose: Lyn kinase is a member of the Src family of non-receptor tyrosine-protein kinases that modifies signals from various cell surface receptors and regulates innate…Abstract Number: 1681 • 2019 ACR/ARP Annual Meeting
The Association of Reduced Low-Density Lipoprotein (LDL) Cholesterol Levels with ANCA-Associated Vasculitis (AAV)
Background/Purpose: ANCA-associated vasculitis (AAV) is a small vessel vasculitis associated with an intense inflammatory state. AAV patients are at a 2-fold higher risk of cardiovascular…Abstract Number: 2632 • 2019 ACR/ARP Annual Meeting
Changing Trends in the Management of ANCA-associated Vasculitis at an Academic Medical Center
Background/Purpose: For years, cyclophosphamide (CYC) has been the primary treatment for severe anca-associated vasculitides (AAV) and has significantly improved disease related mortality. In addition, maintenance…Abstract Number: 869 • 2019 ACR/ARP Annual Meeting
Clinical Manifestations of Patients with Eosinophilic Granulomatosis with Polyangiitis in a Large North American Cohort
Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, systemic necrotizing small-vessel vasculitis, with only a few published North American series. This project aimed to…Abstract Number: 1687 • 2019 ACR/ARP Annual Meeting
Dramatic but Suspensive Effect of interleukin-1 Inhibitors on Persistent Urticarial Vasculitis
Background/Purpose: Urticarial vasculitis (UV) is a rare disease characterized by dermal capillary inflammation responsible for long-lasting urticarial lesions. UV can be separated into 2 different…Abstract Number: 2634 • 2019 ACR/ARP Annual Meeting
ANCA Response upon Rituximab or Cyclophosphamide in ANCA-associated Vasculitis Patients
Background/Purpose: Recent studies have demonstrated that in patients with anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) with successful remission-induction (RI) after cyclophosphamide (CYC), maintenance treatment with…Abstract Number: 821 • 2018 ACR/ARHP Annual Meeting
Comparison of Aortitis Vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm Repair
Comparison of Aortitis vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm RepairBackground/Purpose: Distinguishing aortitis-induced aneurysms from more common non-inflammatory aortic aneurysms is…Abstract Number: 828 • 2018 ACR/ARHP Annual Meeting
Medium and Small-Sized Vessel Involvement in Hypereosinophilic Syndrome
Background/Purpose: Primary systemic vasculitis, especially eosinophilic granulomatosis with polyangiitis and polyarteritis nodosa, can be associated with blood and tissue eosinophilia. Conversely, eosinophilia in the context…Abstract Number: 833 • 2018 ACR/ARHP Annual Meeting
11 Patients with Relapsing Polychondritis Presenting with Severe Airways Disease in One Centre in UK
Background/Purpose: Relapsing polychondritis (RP) is a multi-system disease characterised by episodes of progressive inflammation and subsequent degeneration of cartilage and connective tissue throughout the body.…Abstract Number: 1317 • 2018 ACR/ARHP Annual Meeting
Tracheomalacia in Coventry in UK
Background/Purpose: Tracheomalacia (TM) is pathological diffuse or segmental narrowing of the tracheal lumen, caused by softening of the supporting cartilage and reduction in stiffness of…Abstract Number: 3079 • 2016 ACR/ARHP Annual Meeting
The Characteristic Features of the Patients with Deficiency of Adenosine Deaminase 2 (DADA2)
Background/Purpose: Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disease resulting from a loss-of-function mutation in Cat Eye Syndrome Chromosome Region Candidate…Abstract Number: 1339 • 2015 ACR/ARHP Annual Meeting
Granulomatosis with Polyangiitis or Post Pulmonary Tuberculosis: Can CT Chest Help in Differentiating in a Tuberculosis Endemic Area?
Background/Purpose: The data on the Computed tomography (CT) changes of chest in Granulomatosis with polyangiitis (GPA) is available mostly from low tuberculosis prevalence countries. We…Abstract Number: 1978 • 2015 ACR/ARHP Annual Meeting
Tocilizumab in Refractory Large Vessel Vasculitis with Aorta Involvement. Study on 10 Patients Evaluated By Positron Emission Tomoghraphy
Background/Purpose: Large vessel vasculitis (LVV) with aorta involvement are often refractory to common immunosuppressive therapy. Due to the pathogenic role of IL-6 in, we prospectively…