ACR Meeting Abstracts

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Abstracts tagged "Vasculitis"

  • Abstract Number: 1670 • 2019 ACR/ARP Annual Meeting

    Evaluation of Subclinical Coronary Atherosclerosis in ANCA-associated Small Vessel Vasculitides (AAVs) Compared to Matched Controls Through Visual Assessment of Coronary Arterial Calcium (CAC) Score Using Non-Gated Chest Computed Tomography (CT)

    Sohail Farshad1, Alexandra Halalau 2, Sayf Al-Katib 3, Julie George 4 and Elena Schiopu 5, 1Department of Internal Medicine, Beaumont Health System, Royal Oak, MI, 2Department of Internal Medicine, Beaumont Health System, Royal Oak, 3Department of Radiology, Beaumont Health System, Royal Oak, MI, 4Beaumont Health System, Royal Oak, MI, 5Department of Rheumatology, University of Michigan, Ann Arbor

    Background/Purpose: Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is the most prevalent adult vasculitis and is associated with significant inflammatory burden; chest computed tomography (CT)…
  • Abstract Number: 2104 • 2019 ACR/ARP Annual Meeting

    Vasculitis in HIV-Infected Individuals: Making the Case for an Antigen Driven Process

    Courtney McCray1, Gloria Salazar 2, Ryan Valicek 1, Binh Nguyen 3, Benjamin Naovarat 4, Francis Williams 2 and John Reveille 2, 1University of Texas McGovern Medical School, Houston, TX, 2University of Texas McGovern Medical School, Houston, 3University of Texas McGoven Medical School, Houston, 4University of Texas-McGovern Medical School, Houston, TX

    Background/Purpose: A large spectrum of vasculitides affecting small, medium, and large vessels have been reported in HIV-infected individuals. Although vasculitis is a rare manifestation of…
  • Abstract Number: 1671 • 2019 ACR/ARP Annual Meeting

    Hospital Admissions and Mortality in Patients with ANCA-associated Vasculitis

    Jon Golenbiewski1, Amanda Eudy 2, Megan Clowse 2 and Nancy Allen 2, 1Duke University, Durham, NC, 2Duke University, Durham

    Background/Purpose: ANCA-associated vasculitis (AAV) has a high rate of complications, both from disease itself and treatments. Hospital mortality rates for AAV range between 10-20%. There…
  • Abstract Number: 2281 • 2019 ACR/ARP Annual Meeting

    The Vasculitis Pregnancy Registry (V-PREG): Information from the First 3 Years

    Jon Golenbiewski1, Kalen Young 2, Cristina Burroughs 3, Joyce Kullman 2, Peter Merkel 4 and Megan Clowse 5, 1Duke University Medical Center, Durham, NC, 2Vasculitis Foundation, Kansas City, MO, 3University of South Florida, Tampa, FL, 4University of Pennsylvania, Philadelphia, PA, 5Duke University, Durham

    Background/Purpose: As outcomes for patients with vasculitis improve and treatments become less ovarian-toxic, more women with these diseases will become pregnant. How best to manage…
  • Abstract Number: 1675 • 2019 ACR/ARP Annual Meeting

    A Retrospective Cohort Study Using Clinical Notes and Latent Topic Modeling to Characterize the Natural History of ANCA-Associated Vasculitis

    Liqin Wang1, Eli Miloslavsky 2, John Stone 3, Hyon K. Choi 4, Li Zhou 5 and Zachary Wallace 2, 1Brigham and Women's Hospital, Boston, 2Massachusetts General Hospital, Boston, 3Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, 4Massachusetts General Hospital, Boston, MA, 5Brigham and Women's Hospital, Boston, MA

    Background/Purpose: ANCA-associated vasculitis (AAV) is associated with end-organ damage, complications of treatment, and excess death.  Retrospective studies on the clinical course of AAV, including the…
  • Abstract Number: 2620 • 2019 ACR/ARP Annual Meeting

    Effects of Tofacitinib Suppressed Pulmonary Vascular Remodeling of Allergic Vasculitis in a Murine Model

    Yuka Oikawa1, Kohei Yamauchi 2 and Makoto Maemondo 1, 1Iwate Medical University School of Medicine, Morioka, Japan, Division of Pulmonary medicine, Allergy and Rheumatology, Department of Internal Medicine, morioka, Japan, 2Takizawa central Hospital, morioka, Japan

    Background/Purpose: We reported allergic granulomatous vasculitis with eosinophil infiltration in an asthma model of C57BL/6 sensitized with ovalbumin (OVA). TGF-btea and IL-6 are thought to…
  • Abstract Number: 1677 • 2019 ACR/ARP Annual Meeting

    Management of Severe Renal Disease in Anti-Neutrophil-Cytoplasmic-Antibodies Associated Vasculitis: Role of Rituximab and Plasma Exchange?

    Pauline Morel 1, Alexandre Karras 2, Raphael Porcher 3, Xavier Belenfant 4, Vincent Audard 5, Cédric Rafat 6, Guillaume Hanouna 7, Séverine Beaudreuil 8, Cédric Vilain 9, Aurélie Hummel 10, Benjamin Terrier 11, Evangeline Pillebout 12, Matthieu Groh 13, Romain Jouenne 14, Robin Dhote 15, Olivier Fain 16, Matthieu Ponsoye 17, Nicolas Noel 18, Nicolas Limal 19, Loïc Guillevin 11, Luc Mouthon 11 and Alexis Régent11, 1Cochin Hospital, Paris, France, 2Paris HEGP, Paris, France, 3Hotel Dieu Hospital, Paris, France, 4Service de néphrologie, Hôpital André Grégoire, 56 Boulevard de la Boissière Montreuil, France, Montreuil, Ile-de-France, France, 5Henri Mondor Hospital, Créteil, France, 6Tenon Hospital, Paris, France, 7Service de néphrologie, Hôpital Bichat-Claude Bernard, AP-HP, 46 rue Henri Huchard, Paris, France., Paris, Ile-de-France, France, 8Bicetre Hospital, Le Kremlin Bicetre, France, 9Service de néphrologie hémodialyse, Hôpital Ambroise Paré, APHP, 9 avenue Charles de Gaulle, Boulogne-Billancourt, France, Boulogne-Billancourt, Ile-de-France, France, 10APHP, Paris, France, 11National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, 12Service de néphrologie et transplantation, Hôpital Saint-Louis, AP-HP, 1 avenue Claude Vellefaux, Paris, France., Paris, Ile-de-France, France, 13Service de médecine interne, maladies systémiques, Hôpital Saint Louis, AP-HP, 1 avenue Claude Vellefaux, Paris, France, Paris, Ile-de-France, France, 14Service de médecine interne, Hôpital Bichat-Claude Bernard, AP-HP, 46 rue Henri Huchard, Paris, France, Paris, Ile-de-France, France, 15Service de médecine interne, Hôpital Avicenne, AP-PH, 125 rue de Stalingrad, Bobigny, France, Bobigny, Ile-de-France, France, 16Service de médecine interne, Hôpital Saint-Antoine, AP-HP, 184 rue du Faubourg Saint-Antoine, Paris, France, Paris, Ile-de-France, France, 17Service de médecine interne, Hopital Ambroise Paré, Boulogne-Billancourt, Boulogne-Billancourt, Ile-de-France, France, 18Service de médecine interne et immunologie clinique, Hôpital Bicêtre, AP-HP, 78 rue du Général Leclerc, Kremlin-Bicêtre, France, Kremil-Bicêtre, Ile-de-France, France, 19Service de médecine interne, Hôpital Henri-Mondor, AP-HP, 51 Avenue du Maréchal de Lattre de Tassigny, Créteil, France, Créteil, Ile-de-France, France

    Background/Purpose: Induction therapy for severe ANCA-associated vasculitides (AAVs) is based on the combination of glucocorticoids and cyclophosphamide (CYC) or rituximab (RTX). For patients with severe…
  • Abstract Number: 2621 • 2019 ACR/ARP Annual Meeting

    Association Between Outcome Renal, Clinical Variables and Findings of Renal Biopsy in Patients with ANCA Vasculitis

    Linda Vergel Orduz1, Alejandro Brigante 2, Diego Marino 3, Natalia Perrotta 3, Romina Hassan 4, Gisele Verna 5, Adriana Hamaui 6, Eduardo Kerzberg 7 and Diana Dubinsky 6, 1Sanatorio Guemes, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina, 2Sanatorio Güemes, Servicio de Medicina Interna – Reumatología, Francisco Acuña de Figueroa 1240, C1180AAD, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 3Hospital de Clínicas José de San Martín, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 4Hospital Ramos Mejía, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 5Sanatorio Guemes, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 6Sanatorio Güemes, Buenos Aires, Argentina, 7Hospital Ramos Mejia, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: In associated ANCA vasculitis (AAV), rapidly progressive glomerulonephritis (GN) is one of the most serious complications. In 40% of cases they progress to chronic…
  • Abstract Number: 821 • 2018 ACR/ARHP Annual Meeting

    Comparison of Aortitis Vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm Repair

    Laarni Quimson1, Bryan Rea2 and Rennie L. Rhee3, 1Internal Medicine, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Comparison of Aortitis vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm RepairBackground/Purpose: Distinguishing aortitis-induced aneurysms from more common non-inflammatory aortic aneurysms is…
  • Abstract Number: 828 • 2018 ACR/ARHP Annual Meeting

    Medium and Small-Sized Vessel Involvement in Hypereosinophilic Syndrome

    Julien Rohmer1, Matthieu Groh2, Maxime Samson3, Jonathan London4, Marie JACHIET5, Diane Rouzaud6, Antoinette Perlat7, Romain Paule8, Felipe SUAREZ9, Jean-Emmanuel Kahn10, Loïc Guillevin11 and Benjamin Terrier12, 1National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Internal medicine, France, Paris, France, 2Internal Medicine, Foch, Suresnes, France, 3Dijon University Hospital, Dijon, France, 4Service de Médecine Interne, Hôpital Cochin, Centre de référence national pour les maladies systémiques autoimmunes rares d’Ile de France, DHU Authors, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France, Paris, France, 5Dermatology department, St Louis Hospital, Paris, France, 6Université Paris-Diderot, Paris, France, 7Internal medicine, CHU de Rennes, Rennes, France, 8Department of Internal Medicine, Department of Internal Medicine, Cochin University Hospital, Paris, France, 9Hematology Department, Necker Hospital, Paris, France, 10Service de Médecine Interne, Centre de Référence des Syndromes Hyperéosinophiliques-CEREO, Hôpital Foch, Université Versailles–Saint-Quentin-en-Yvelines, Suresnes, France, 11Medecine Interne, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 12National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France

    Background/Purpose: Primary systemic vasculitis, especially eosinophilic granulomatosis with polyangiitis and polyarteritis nodosa, can be associated with blood and tissue eosinophilia. Conversely, eosinophilia in the context…
  • Abstract Number: 833 • 2018 ACR/ARHP Annual Meeting

    11 Patients with Relapsing Polychondritis Presenting with Severe Airways Disease in One Centre in UK

    Shirish Dubey1, Grace Pink2, Asad Ali2, Nicholas Hart3, Patrick Murphy4, Joanne Shakespeare5, Colin Gelder6, Chris Taylor2 and David D'Cruz7, 1Rheumatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 2Respiratory medicine, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 3Respiratory medicine, St Thomas' Hospital, London, United Kingdom, 4Lane Fox Respiratory Unit, St Thomas' Hospital, London, United Kingdom, 5Respiratory physiology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 6University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 7Louise Coote Lupus Unit, Guy's and St. Thomas' Hospital, London, United Kingdom

    Background/Purpose: Relapsing polychondritis (RP) is a multi-system disease characterised by episodes of progressive inflammation and subsequent degeneration of cartilage and connective tissue throughout the body.…
  • Abstract Number: 1317 • 2018 ACR/ARHP Annual Meeting

    Tracheomalacia in Coventry in UK

    Grace Pink1, Shirish Dubey2, Asad Ali1, Joanna Shakespeare3, Chris Taylor1 and Colin Gelder4, 1Respiratory medicine, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 2Rheumatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 3Respiratory Physiology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 4University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom

    Background/Purpose: Tracheomalacia (TM) is pathological diffuse or segmental narrowing of the tracheal lumen, caused by softening of the supporting cartilage and reduction in stiffness of…
  • Abstract Number: 3079 • 2016 ACR/ARHP Annual Meeting

    The Characteristic Features of the Patients with Deficiency of Adenosine Deaminase 2 (DADA2)

    Abdulsamet Erden1, Ezgi Deniz Batu2, Ekim Z. Taskiran3, Hafize Emine Sonmez2, Alper Sari1, Berkan Armagan1, Levent Kilic1, Zehra Serap Arıcı4, Yelda Bilginer5, Ali Akdogan1, Omer Karadag1, Umut Kalyoncu1 and Seza Ozen6,7, 1Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 3Department of Medical Genetics, Hacettepe University Faculty of Medicine, ANKARA, Turkey, 4Departments of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 5Departments of Pediatric Nephrology and Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 6Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey, 7Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, ANKARA, Turkey

    Background/Purpose: Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disease resulting from a loss-of-function mutation in Cat Eye Syndrome Chromosome Region Candidate…
  • Abstract Number: 1339 • 2015 ACR/ARHP Annual Meeting

    Granulomatosis with Polyangiitis or Post Pulmonary Tuberculosis: Can CT Chest Help in Differentiating in a Tuberculosis Endemic Area?

    Aman Sharma1, Manphool Singhal2, Mitali Sen3, Manish Rathi4, Varun Dhir1, Kusum Sharma5, Ranjana Minz6, Surjit Singh3, Pradeep Bambery7 and Niranjan Khandelwal2, 1Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India, 2Department of Radiodiagnosis, PGIMER,, Chandigarh, India, 3Department of Internal Medicine,, PGIMER,, Chandigarh, India, 4Department of Nephrology,, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 5Department of Medical Microbiology,, PGIMER,, Chandigarh, India, 6Department of Immunopathology,, PGIMER,, Chandigarh, India, 7Rheumatology, Bundaberg base hospital, University of Queensland, Bundaberg, Australia

    Background/Purpose: The data on the Computed tomography (CT) changes of chest in Granulomatosis with polyangiitis (GPA) is available mostly from low tuberculosis prevalence countries. We…
  • Abstract Number: 1978 • 2015 ACR/ARHP Annual Meeting

    Tocilizumab in Refractory Large Vessel Vasculitis with Aorta Involvement. Study on 10 Patients Evaluated By Positron Emission Tomoghraphy

    Carlotta Nannini1, Stelvio Sestini2, Laura Niccoli3, Emanuele Cassarà4, Olga Kaloudi5 and Fabrizio Cantini6, 1Rheumatology, Prato Hospital, Prato, Italy, 2Radiology Department, Prato, Italy, 3Prato Hospital, Prato, Italy, 4Rheumatology, Hospital of Prato, Prato, Italy, 5PRato, Prato Hospital, Prato, Italy, 6Prato, Prato, Italy

    Background/Purpose: Large vessel vasculitis (LVV) with aorta involvement are often refractory to common immunosuppressive therapy. Due to the pathogenic role of IL-6 in, we prospectively…
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