Abstracts tagged "Validity"

Abstract Number: 1176 • 2014 ACR/ARHP Annual Meeting
Feasibility and Clinical Implication of Radiocarpal Cartilage T_1ρ MR Imaging in Rheumatoid Arthritis
Valentina Pedoia¹, Favian Su², Andrew J. Burghardt¹, Jonathan Graft³, John B. Imboden³, Mary Nakamura⁴, Ursula Heilmeier¹, Thomas M Link⁵ and Xiaojuan Li⁵, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ²Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, ⁴Arthritis/Rheumatology 111-R, SFVAMC/UCSF, San Francisco, CA, ⁵Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose Rheumatoid arthritic (RA) disease progression and anti-rheumatic treatment efficacy have traditionally been monitored by evaluation of radiographs. However, MRI has emerged as a more…
Abstract Number: 711 • 2014 ACR/ARHP Annual Meeting
Is the Disease-Specific Lupusqol Sensitive to Changes of Disease Activity in SLE Patients after Treatment of a Flare?
Kathleen McElhone¹, Jane Burnell², Chris Sutton², Janice Abbott³, Peter Lanyon⁴, Anisur Rahman⁵, Chee-Seng Yee⁶, Mohammed Akil⁷, Yasmeen Ahmad⁸, Ian Bruce⁹, Caroline Gordon¹⁰ and Lee-Suan Teh¹¹, ¹Rheumatology, Royal Blackburn Hospital, Blackburn, United Kingdom, ²School of Health, University of Central Lancashire, Preston, United Kingdom, ³University of Central Lancashire, Preston, United Kingdom, ⁴Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom, ⁵Centre for Rheumatology Research, University College London, London, United Kingdom, ⁶Department of Rheumatology, Doncaster and Bassetlaw Hospitals NHS Foundation Trust, Doncaster, United Kingdom, ⁷Sheffield Center Rheumatic Dis, Sheffield South Yorkshire, United Kingdom, ⁸Department of Rheumatology, Peter Maddison Research Centre, Bangor, United Kingdom, ⁹Kellgren Centre for Rheum, Arthritis Research UK Epidemiology Unit, Institution of Inflammation and Repair, University of Manchester, NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ¹⁰Rheumatology Research Group, School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ¹¹Department of Rheumatology, Royal Blackburn Hospital, Blackburn, United Kingdom
Background/Purpose With improving survival in SLE patients, patient-reported health-related quality of life (HRQoL) has become an important outcome. The LupusQoL is a disease-specific patient-derived HRQoL measure…
Abstract Number: 369 • 2014 ACR/ARHP Annual Meeting
Validation of Snapshot, a Rheumatoid Arthritis Assessment Tool, Against CDAI, DAS28 (ESR), and DAS28 (CRP) in Canadian Patients with Rheumatoid Arthritis
William G Bensen¹, Wynn Bensen², Melissa Deamude², Cynthia Mech³, Robert Bensen⁴, Arthur N. Lau⁵ and Alpesh Shah⁶, ¹St Josephs Hospital and McMaster University, Hamilton, ON, Canada, ²Dr William G Bensen Medicine Professional Corp, Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ³Dr. William G. Bensen, Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁴Rheumatology Health Team, Dr. Bensen's Rheumatology Clinic, Hamilton, ON, Canada, ⁵Rheumatology and Clinical Epidemiology, Division of Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Epidemiology and Biostatistics, University of Western Ontario, MSc in Clinical Epidemiology, University of Western Ontario, London, ON, Canada
Background/Purpose: Measuring disease activity in Rheumatoid Arthritis (RA) remains an elusive goal. Both DAS and CDAI have an inherent weakness because similar numbers can result…
Abstract Number: 377 • 2014 ACR/ARHP Annual Meeting
Fatigue Fluctuates Substantially over Time in Rheumatoid Arthritis Patients Despite Stable Disease Activity during Treatment with Biological Agents
Emilie Lund Egsmose¹, René Cordtz¹ and Ole Rintek Madsen², ¹Dept. of Rheumatology/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark, ²Dept. of Rheumatoglogy/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark
Background/Purpose Fatigue (FTG) is a symptom commonly reported by patients with rheumatoid arthritis (RA). Little is known about its nature and etiology. The number of…
Abstract Number: 1910 • 2013 ACR/ARHP Annual Meeting
Validation Of The Mayo Hip Questionnaire: Validity and Sensitivity To Change
Jasvinder A. Singh¹, Cathy Schleck², W. Scott Harmsen³ and David Lewallen⁴, ¹Department of Medicine, University of Alabama, Tuscaloosa, AL, ²Mayo Clinic College of Medicine, Rochester, MN, ³Mayo Clinic, Rochester, MN, ⁴Orthopedics, Mayo Clinic college of medicine, Rochester, MN
Background/Purpose: Mayo Hip questionnaire has previously been shown to have face, content and test-retest reliability. Our objective was to assess the validity and responsiveness of the…
Abstract Number: 1926 • 2013 ACR/ARHP Annual Meeting
Validation Of The Hospital For Special Surgery Knee Questionnaire: Convergent Validity, Responsiveness and Sensitivity To Change
Jasvinder A. Singh^1,2, Cathy Schleck³, W. Scott Harmsen⁴ and David Lewallen⁵, ¹Rheumatology, Birmingham VA, Birmingham, AL, ²Department of Medicine, University of Alabama, Tuscaloosa, AL, ³Mayo Clinic College of Medicine, Rochester, MN, ⁴Mayo Clinic, Rochester, MN, ⁵Orthopedics, Mayo Clinic college of medicine, Rochester, MN
Background/Purpose: Hospital for Special Surgery (HSS) Knee questionnaire has previously been shown to have construct validity. Our objective was to further assess the validity and responsiveness…
Abstract Number: 1578 • 2013 ACR/ARHP Annual Meeting
Decreased Sensitivity Of a Commercial Anti-dsDNA Assay In Patients With Moderately To Severely Active Systemic Lupus Erythematosus
Munther A. Khamashta¹, Gabor G. Illei², Stephen Yoo², Liangwei Wang³ and Warren Greth², ¹Lupus Research Unit, The Rayne Institute, St Thomas Hospital, Kings College London School of Medicine, London, United Kingdom, ²Clinical Development, MedImmune, LLC, Gaithersburg, MD, ³Biostatistics, MedImmune, LLC, Gaithersburg, MD
Background/Purpose: Anti-dsDNA autoantibodies are highly specific for SLE. Anti-dsDNA positivity is an important eligibility criterion in many SLE studies, and decreases in anti-dsDNA levels are…
Abstract Number: 1550 • 2013 ACR/ARHP Annual Meeting
Validation Of The Ankylosing Spondylitis Disease Activity Score and Effectiveness Of Infliximab In The Treatment Of Ankylosing Spondylitis Over 4 Years: The Canadian Experience
Proton Rahman¹, Denis Choquette², Majed M. Khraishi³, William G. Bensen⁴, Saeed A. Shaikh⁵, Dalton E. Sholter⁶, Maqbool K. Sheriff⁷, Emmanouil Rampakakis⁸, John S. Sampalis⁸, Francois Nantel⁹, Susan M. Otawa¹⁰, Allen J. Lehman¹⁰ and May Shawi¹¹, ¹Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ²Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ³Nexus Clinical Research, St John's, NF, Canada, ⁴Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁵Medicine, McMaster University, St Catharines, ON, Canada, ⁶Rheumatology Associates, Edmonton, AB, Canada, ⁷Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ⁸JSS Medical Research, Montreal, QC, Canada, ⁹Janssen Inc., Toronto, ON, Canada, ¹⁰Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹¹Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: The efficacy of anti-TNF in the management of Ankylosing Spondylitis (AS) has been demonstrated in numerous controlled clinical trials. The objective of this study…
Abstract Number: 2887 • 2013 ACR/ARHP Annual Meeting
The Spondyloarthritis Research Consortium Of Canada MRI Sacroiliac Joint Structural Score: A Method For Reliable Detection Of Structural Progression
Walter P. Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Robert GW Lambert³ and Susanne Juhl Pedersen⁴, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Mahidol University, Bangkok, Thailand, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark
Background/Purpose: With increasing focus on effective treatment intervention in early spondyloarthritis, there is an unmet need for reliable assessment of structural progression in the…
Abstract Number: 1182 • 2013 ACR/ARHP Annual Meeting
The Performance Of a Diagnostic Rule For Acute Gouty Arthritis Without Joint Fluid Analysis: a Validation Study
Laura Kienhorst¹, Hein Janssens², Jaap Fransen³ and Matthijs Janssen¹, ¹Department of Rheumatology, Rijnstate Hospital, Arnhem, Netherlands, ²Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: The gold standard to diagnose gout is the identification of monosodium urate (MSU) crystals in joint fluid. In primary care gout is mostly diagnosed…
Abstract Number: 2871 • 2013 ACR/ARHP Annual Meeting
Validation Of The FLARE Self-Report Questionnaire For Assessing FLARE Out Of The Clinical Visit In Rheumatoid Arthritis
Jacques Morel¹, Jean-Marie Berthelot², Arnaud L. Constantin³, Michel De Bandt⁴, Philippe Gaudin⁵, Olivier Vittecoq⁶, Jean Francis Maillefert⁷, Olivier Meyer⁸, Thao Pham⁹, Alain Saraux¹⁰, Elisabeth Solau Gervais¹¹, Elisabeth Spitz¹², Daniel Wendling¹³, Francis Guillemin¹⁴ and Bruno Fautrel¹⁵, ¹Department of Rheumatology, Hôpital Lapeyronie, Montpellier, France, ²Rheumatology Unit, Nantes University Hospital, Nantes, France, ³Rheumatology, Purpan University Hospital, Toulouse, France, ⁴Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, ⁵Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁶Rheumatology, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen, France, ⁷University Hospital, Department of Rheumatology, Dijon, France, ⁸Rheumatology, Bichat University Hospital, Paris, France, ⁹Rheumatology Department, Sainte Marguerite Hospital, Marseille, France, ¹⁰Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, ¹¹Departement of Rheumatology, CHU de Poitiers, Poitiers, France, ¹²UFR Sciences Humaines et Arts, APEMAC-EA4360, Metz, France, ¹³Rheumatology, University Hospital, Besancon, France, ¹⁴CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ¹⁵Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France
Background/Purpose: Defining flare in rheumatoid arthritis (RA) raises a complex issue related to the difference in perception or concept of flare between patients or health…
Abstract Number: 2692 • 2013 ACR/ARHP Annual Meeting
Evidence That Fat Metaplasia Is a Key Intermediary In The Development Of Sacroiliac Joint Ankylosis Following Repair Of Erosions In Patients With Spondyloarthritis
Walter P. Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Robert GW Lambert³ and Susanne Juhl Pedersen⁴, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Mahidol University, Bangkok, Thailand, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark
Background/Purpose: Fat metaplasia is detected as bright signal on T1W MRI and has been shown to develop after resolution of inflammation in spine and sacroiliac…
Abstract Number: 2520 • 2013 ACR/ARHP Annual Meeting
A Freely Accessible Toolbox For Patient-Reported Outcomes: Development and Systematic Literature Review For Lupus Instruments
Isabel Castrejón¹, Loreto Carmona^2,3, Robin Christensen⁴, Till Uhlig⁵, Birgit Prodinger⁶, Francis Guillemin⁷, Marieke Scholte-Voshaar⁸ and Laure Gossec^9,10, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Health Sciences School, Universidad Camilo José Cela, Villanueva de la Cañada, Spain, ³Institute for Musculoskeletal Health, Madrid, Spain, ⁴Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶ICF Research Branch, Swiss Paraplegic Group, Nottwil, Switzerland, Notwill, Switzerland, ⁷CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ⁸EULAR Standing Committee of People with Arthritis/Rheumatism in Europe, Zurich, Switzerland, ⁹Cochin University Hospital, Paris, France, ¹⁰Rheumatology, PitiéSalpêtrière Hospital, Pierre et Marie Curie University, Paris, France
Background/Purpose: Patient self-report has become prominent in the assessment of rheumatic and musculoskeletal diseases (RMD). In a workshop on priorities in PROs in 2009 it…
Abstract Number: 2481 • 2013 ACR/ARHP Annual Meeting
External Validation Of The Spondyloarthritis Radiography Online Reference Module For Training Readers To Score The Modified Stoke Ankylosing Spondylitis Score
Praveena Chiowchanwisawakit¹, Susanne Juhl Pedersen² and Walter P. Maksymowych³, ¹Mahidol University, Bangkok, Thailand, ²Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ³Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) is commonly used to assess disease severity and progression in patients with AS; however, the reliability…
Abstract Number: 2461 • 2013 ACR/ARHP Annual Meeting
Quality Of Life, Physical Function and Symptoms In Non-Radiographic Axial Spondyloarthritis:The Patient Perspective
Philip J. Mease¹, Sumati A Rao², Avani D. Joshi², Sarah Clifford³, Christina Vernon³ and Mary A. Cifaldi², ¹Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, ²AbbVie Inc., North Chicago, IL, ³United BioSource Corporation, Bethesda, MD
Background/Purpose: Pain, physical function impairment, and health-related quality of life (HRQoL) impact are substantial for patients with non-radiographic axial spondyloarthritis (nr-axSpA).1 Understanding the most important…

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